메뉴 건너뛰기




Volumn 225, Issue 2, 2015, Pages R49-R66

The involvement of gonadotropin inhibitory hormone and kisspeptin in the metabolic regulation of reproduction

Author keywords

Ghrelin; GnIH; GPR147; Kiss1r; Kisspeptin; Leptin; Metabolism; Reproduction

Indexed keywords

GONADOTROPIN; GONADOTROPIN INHIBITORY HORMONE; KISSPEPTIN; NEUROPEPTIDE; UNCLASSIFIED DRUG; HYPOTHALAMUS HORMONE;

EID: 84930811492     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1530/JOE-14-0688     Document Type: Review
Times cited : (45)

References (197)
  • 1
    • 84907221163 scopus 로고    scopus 로고
    • Selective deletion of leptin receptors in gonadotropes reveals activin and GnRH-binding sites as leptin targets in support of fertility
    • Akhter N, Carl Lee T, Syed MM, Odle AK, Cozart MA, Haney AC, Allensworth-James ML, Beneš H & Childs GV 2014 Selective deletion of leptin receptors in gonadotropes reveals activin and GnRH-binding sites as leptin targets in support of fertility. Endocrinology 155 4027-4042. (doi:10.1210/en.2014-1132)
    • (2014) Endocrinology , vol.155 , pp. 4027-4042
    • Akhter, N.1    Carl Lee, T.2    Syed, M.M.3    Odle, A.K.4    Cozart, M.A.5    Haney, A.C.6    Allensworth-James, M.L.7    Beneš, H.8    Childs, G.V.9
  • 2
    • 0030943482 scopus 로고    scopus 로고
    • Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men
    • Aloi JA, Bergendahl M, Iranmanesh A & Veldhuis JD 1997 Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men. Journal of Clinical Endocrinology and Metabolism 82 1543-1548.
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , pp. 1543-1548
    • Aloi, J.A.1    Bergendahl, M.2    Iranmanesh, A.3    Veldhuis, J.D.4
  • 3
    • 84907865005 scopus 로고    scopus 로고
    • Inhibitory roles of the mammalian GnIH ortholog RFRP3 in testicular activities in adult mice
    • Anjum S, Krishna A & Tsutsui K 2014 Inhibitory roles of the mammalian GnIH ortholog RFRP3 in testicular activities in adult mice. Journal of Endocrinology 223 79-91. (doi:10.1530/JOE-14-0333)
    • (2014) Journal of Endocrinology , vol.223 , pp. 79-91
    • Anjum, S.1    Krishna, A.2    Tsutsui, K.3
  • 4
    • 71949110404 scopus 로고    scopus 로고
    • Melanocortins may stimulate reproduction by activating orexin neurons in the dorsomedial hypothalamus and kisspeptin neurons in the preoptic area of the ewe
    • Backholer K, Smith J & Clarke IJ 2009 Melanocortins may stimulate reproduction by activating orexin neurons in the dorsomedial hypothalamus and kisspeptin neurons in the preoptic area of the ewe. Endocrinology 150 5488-5497. (doi:10.1210/en.2009-0604)
    • (2009) Endocrinology , vol.150 , pp. 5488-5497
    • Backholer, K.1    Smith, J.2    Clarke, I.J.3
  • 5
    • 77953148020 scopus 로고    scopus 로고
    • Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells
    • Backholer K, Smith JT, Rao A, Pereira A, Iqbal J, Ogawa S, Li Q & Clarke IJ 2010 Kisspeptin cells in the ewe brain respond to leptin and communicate with neuropeptide Y and proopiomelanocortin cells. Endocrinology 151 2233-2243. (doi:10.1210/en.2009-1190)
    • (2010) Endocrinology , vol.151 , pp. 2233-2243
    • Backholer, K.1    Smith, J.T.2    Rao, A.3    Pereira, A.4    Iqbal, J.5    Ogawa, S.6    Li, Q.7    Clarke, I.J.8
  • 6
    • 84915733714 scopus 로고    scopus 로고
    • Acute fasting-induced repression of the hypothalamic-pituitary-gonadal axis is reversed by RF-9 administration in the adult male macaque
    • Batool A, Naz R, Wazir M, Azam A, Ullah R, Wahab F & Shahab M 2014 Acute fasting-induced repression of the hypothalamic-pituitary-gonadal axis is reversed by RF-9 administration in the adult male macaque. Hormone and Metabolic Research 46 927-832. (doi:10.1055/s-0034-1387788)
    • (2014) Hormone and Metabolic Research , vol.46 , pp. 832-927
    • Batool, A.1    Naz, R.2    Wazir, M.3    Azam, A.4    Ullah, R.5    Wahab, F.6    Shahab, M.7
  • 7
    • 0029081066 scopus 로고
    • Herman Award Lecture, 1995: infection-induced malnutrition - from cholera to cytokines
    • Beisel WR 1995 Herman Award Lecture, 1995: infection-induced malnutrition - from cholera to cytokines. American Journal of Clinical Nutrition 62 813-819.
    • (1995) American Journal of Clinical Nutrition , vol.62 , pp. 813-819
    • Beisel, W.R.1
  • 9
    • 78649505408 scopus 로고    scopus 로고
    • Recent studies of gonadotropininhibitory hormone (GnIH) in the mammalian hypothalamus, pituitary and gonads
    • Bentley GE, Tsutsui K & Kriegsfeld LJ 2010 Recent studies of gonadotropininhibitory hormone (GnIH) in the mammalian hypothalamus, pituitary and gonads. Brain Research 1364 62-71. (doi:10.1016/j.brainres.2010.10.001)
    • (2010) Brain Research , vol.1364 , pp. 62-71
    • Bentley, G.E.1    Tsutsui, K.2    Kriegsfeld, L.J.3
  • 10
    • 0026031457 scopus 로고
    • Starvation-induced suppression of pituitary-testicular function in rats is reversed by pulsatile gonadotropin-releasing hormone substitution
    • Bergendahl M, Perheentupa A & Huhtaniemi I 1991 Starvation-induced suppression of pituitary-testicular function in rats is reversed by pulsatile gonadotropin-releasing hormone substitution. Biology of Reproduction 44 413-419. (doi:10.1095/biolreprod44.3.413)
    • (1991) Biology of Reproduction , vol.44 , pp. 413-419
    • Bergendahl, M.1    Perheentupa, A.2    Huhtaniemi, I.3
  • 12
    • 37549000647 scopus 로고    scopus 로고
    • Ki SS-1 mRNA in adipose tissue is regulated by sex hormones and food intake
    • Brown RE, Imran SA, Ur E & Wilkinson M 2008 Ki SS-1 mRNA in adipose tissue is regulated by sex hormones and food intake. Molecular and Cellular Endocrinology 281 64-72. (doi:10.1016/j.mce.2007.10.011)
    • (2008) Molecular and Cellular Endocrinology , vol.281 , pp. 64-72
    • Brown, R.E.1    Imran, S.A.2    Ur, E.3    Wilkinson, M.4
  • 13
    • 84910626146 scopus 로고    scopus 로고
    • Prolactin regulation of kisspeptin neurones in the mouse brain and its role in the lactation-induced suppression of kisspeptin expression
    • Brown RSE, Herbison AE & Grattan DR 2014 Prolactin regulation of kisspeptin neurones in the mouse brain and its role in the lactation-induced suppression of kisspeptin expression. Journal of Neuroendocrinology 26 898-908. (doi:10.1111/jne.12223)
    • (2014) Journal of Neuroendocrinology , vol.26 , pp. 898-908
    • Brown, R.S.E.1    Herbison, A.E.2    Grattan, D.R.3
  • 14
    • 33646422404 scopus 로고    scopus 로고
    • Interactions of the hormones leptin, ghrelin, adiponectin, resistin, and PYY3-36 with the reproductive system
    • Budak E, Fernández Sánchez M, Bellver J, Cerveró A, Simón C & Pellicer A 2006 Interactions of the hormones leptin, ghrelin, adiponectin, resistin, and PYY3-36 with the reproductive system. Fertility and Sterility 85 1563-1581. (doi:10.1016/j.fertnstert.2005.09.065)
    • (2006) Fertility and Sterility , vol.85 , pp. 1563-1581
    • Budak, E.1    Fernández Sánchez, M.2    Bellver, J.3    Cerveró, A.4    Simón, C.5    Pellicer, A.6
  • 15
    • 0026324549 scopus 로고
    • Metabolic cues for the onset of puberty
    • Cameron JL 1991 Metabolic cues for the onset of puberty. Hormone Research 36 97-103. (doi:10.1159/000182141)
    • (1991) Hormone Research , vol.36 , pp. 97-103
    • Cameron, J.L.1
  • 16
    • 0030131980 scopus 로고    scopus 로고
    • Regulation of reproductive hormone secretion in primates by short-term changes in nutrition
    • Cameron JL 1996 Regulation of reproductive hormone secretion in primates by short-term changes in nutrition. Reviews of Reproduction 1 117-126. (doi:10.1530/ror.0.0010117)
    • (1996) Reviews of Reproduction , vol.1 , pp. 117-126
    • Cameron, J.L.1
  • 24
    • 84860344698 scopus 로고    scopus 로고
    • Analysis of the expression of neurokinin B, kisspeptin, and their cognate receptors NK3R and KISS1R in the human female genital tract
    • Cejudo Roman A, Pinto FM, Dorta I, Almeida TA, Hernández M, Illanes M, Tena-Sempere M & Candenas L 2012 Analysis of the expression of neurokinin B, kisspeptin, and their cognate receptors NK3R and KISS1R in the human female genital tract. Fertility and Sterility 97 1213-1219. (doi:10.1016/j.fertnstert.2012.02.021)
    • (2012) Fertility and Sterility , vol.97 , pp. 1213-1219
    • Cejudo Roman, A.1    Pinto, F.M.2    Dorta, I.3    Almeida, T.A.4    Hernández, M.5    Illanes, M.6    Tena-Sempere, M.7    Candenas, L.8
  • 25
    • 79960555999 scopus 로고    scopus 로고
    • Control of GnRH secretion: one step back
    • Clarke IJ 2011 Control of GnRH secretion: one step back. Frontiers in Endocrinology 32 367-375.
    • (2011) Frontiers in Endocrinology , vol.32 , pp. 367-375
    • Clarke, I.J.1
  • 27
    • 84896728516 scopus 로고    scopus 로고
    • Gonadotropin inhibitory hormone (GnIH) as a regulator of gonadotropes
    • Clarke IJ & Parkington HC 2014 Gonadotropin inhibitory hormone (GnIH) as a regulator of gonadotropes. Molecular and Cellular Endocrinology 385 36-44. (doi:10.1016/j.mce.2013.08.017)
    • (2014) Molecular and Cellular Endocrinology , vol.385 , pp. 36-44
    • Clarke, I.J.1    Parkington, H.C.2
  • 29
    • 33751538038 scopus 로고    scopus 로고
    • Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons
    • Clarkson J & Herbison AE 2006 Postnatal development of kisspeptin neurons in mouse hypothalamus; sexual dimorphism and projections to gonadotropin-releasing hormone neurons. Endocrinology 147 5817-5825. (doi:10.1210/en.2006-0787)
    • (2006) Endocrinology , vol.147 , pp. 5817-5825
    • Clarkson, J.1    Herbison, A.E.2
  • 31
    • 0031811710 scopus 로고    scopus 로고
    • Reproductive endocrinopathy in acute streptozotocin-induced diabetic male rats. Studies on LHRH
    • Clough RW, Kienast SG & Steger RW 1998 Reproductive endocrinopathy in acute streptozotocin-induced diabetic male rats. Studies on LHRH. Endocrine 8 37-43. (doi:10.1385/ENDO:8:1:37)
    • (1998) Endocrine , vol.8 , pp. 37-43
    • Clough, R.W.1    Kienast, S.G.2    Steger, R.W.3
  • 35
    • 35948997633 scopus 로고    scopus 로고
    • Neuropeptide signaling in the integration of metabolism and reproduction
    • Crown A, Clifton DK & Steiner RA 2007 Neuropeptide signaling in the integration of metabolism and reproduction. Neuroendocrinology 86 175-182. (doi:10.1159/000109095)
    • (2007) Neuroendocrinology , vol.86 , pp. 175-182
    • Crown, A.1    Clifton, D.K.2    Steiner, R.A.3
  • 37
    • 56549128570 scopus 로고    scopus 로고
    • Kisspeptin immunoreactive neurons in the equine hypothalamus Interactions with GnRH neuronal system
    • Decourt C, Tillet Y, Caraty A, Franceschini I & Briant C 2008 Kisspeptin immunoreactive neurons in the equine hypothalamus Interactions with GnRH neuronal system. Journal of Chemical Neuroanatomy 36 131-137. (doi:10.1016/j.jchemneu.2008.07.008)
    • (2008) Journal of Chemical Neuroanatomy , vol.36 , pp. 131-137
    • Decourt, C.1    Tillet, Y.2    Caraty, A.3    Franceschini, I.4    Briant, C.5
  • 38
    • 0037291831 scopus 로고    scopus 로고
    • Regulation of serum leptin and its role in the hyperphagia of lactation in the rat
    • Denis RG, Williams G & Vernon RG 2003 Regulation of serum leptin and its role in the hyperphagia of lactation in the rat. Journal of Endocrinology 176 193-203. (doi:10.1677/joe.0.1760193)
    • (2003) Journal of Endocrinology , vol.176 , pp. 193-203
    • Denis, R.G.1    Williams, G.2    Vernon, R.G.3
  • 39
    • 0141814637 scopus 로고    scopus 로고
    • Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
    • De Roux N, Genin E, Carel J-C, Matsuda F, Chaussain J-L & Milgrom E 2003 Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. PNAS 100 10972-10976. (doi:10.1073/pnas.1834399100)
    • (2003) PNAS , vol.100 , pp. 10972-10976
    • De Roux, N.1    Genin, E.2    Carel, J.-C.3    Matsuda, F.4    Chaussain, J.-L.5    Milgrom, E.6
  • 42
    • 61849153749 scopus 로고    scopus 로고
    • RFamide-related peptide-3, a mammalian gonadotropin-inhibitory hormone ortholog, regulates gonadotropin-releasing hormone neuron firing in the mouse
    • Ducret E, Anderson GM & Herbison AE 2009 RFamide-related peptide-3, a mammalian gonadotropin-inhibitory hormone ortholog, regulates gonadotropin-releasing hormone neuron firing in the mouse. Endocrinology 150 2799-2804. (doi:10.1210/en.2008-1623)
    • (2009) Endocrinology , vol.150 , pp. 2799-2804
    • Ducret, E.1    Anderson, G.M.2    Herbison, A.E.3
  • 43
    • 51149105501 scopus 로고    scopus 로고
    • Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons
    • Dumalska I, Wu M, Morozova E, Liu R, van den Pol A & Alreja M 2008 Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons. Journal of Neuroscience 28 8003-8013. (doi:10.1523/JNEUROSCI.1225-08.2008)
    • (2008) Journal of Neuroscience , vol.28 , pp. 8003-8013
    • Dumalska, I.1    Wu, M.2    Morozova, E.3    Liu, R.4    van den Pol, A.5    Alreja, M.6
  • 44
    • 84880711207 scopus 로고    scopus 로고
    • Expression of kisspeptins and kiss receptors suggests a large range of functions for kisspeptin systems in the brain of the European sea bass
    • Escobar S, Servili A, Espigares F, Gueguen M-M, Brocal I, Felip A, Gómez A, Carrillo M, Zanuy S & Kah O 2013 Expression of kisspeptins and kiss receptors suggests a large range of functions for kisspeptin systems in the brain of the European sea bass. PLoS ONE 8 e70177. (doi:10.1371/journal.pone.0070177)
    • (2013) PLoS ONE , vol.8 , pp. e70177
    • Escobar, S.1    Servili, A.2    Espigares, F.3    Gueguen, M.-M.4    Brocal, I.5    Felip, A.6    Gómez, A.7    Carrillo, M.8    Zanuy, S.9    Kah, O.10
  • 45
    • 67349194989 scopus 로고    scopus 로고
    • Effects of ghrelin on Kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinising hormone secretion in the female rat
    • Forbes S, Li XF, Kinsey-Jones J & O'Byrne K 2009 Effects of ghrelin on Kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinising hormone secretion in the female rat. Neuroscience Letters 460 143-147. (doi:10.1016/j.neulet.2009.05.060)
    • (2009) Neuroscience Letters , vol.460 , pp. 143-147
    • Forbes, S.1    Li, X.F.2    Kinsey-Jones, J.3    O'Byrne, K.4
  • 46
    • 0021921216 scopus 로고
    • Effect of restricted nutrition on puberty in the lamb: patterns of tonic luteinizing hormone (LH) secretion and competency of the LH surge system
    • Foster DL & Olster DH 1985 Effect of restricted nutrition on puberty in the lamb: patterns of tonic luteinizing hormone (LH) secretion and competency of the LH surge system. Endocrinology 116 375-381. (doi:10.1210/endo-116-1-375)
    • (1985) Endocrinology , vol.116 , pp. 375-381
    • Foster, D.L.1    Olster, D.H.2
  • 48
    • 77955373372 scopus 로고    scopus 로고
    • Kisspeptin directly excites anorexigenic proopiomelanocortin neurons but inhibits orexigenic neuropeptide Y cells by an indirect synaptic mechanism
    • Fu L-Y & van den Pol AN 2010 Kisspeptin directly excites anorexigenic proopiomelanocortin neurons but inhibits orexigenic neuropeptide Y cells by an indirect synaptic mechanism. Journal of Neuroscience 30 10205-10219. (doi:10.1523/JNEUROSCI.2098-10.2010)
    • (2010) Journal of Neuroscience , vol.30 , pp. 10205-10219
    • Fu, L.-Y.1    van den Pol, A.N.2
  • 52
    • 84867798461 scopus 로고    scopus 로고
    • Kisspeptin and the hypothalamic control of reproduction: lessons from the human
    • George JT & Seminara SB 2012 Kisspeptin and the hypothalamic control of reproduction: lessons from the human. Endocrinology 153 5130-5136. (doi:10.1210/en.2012-1429)
    • (2012) Endocrinology , vol.153 , pp. 5130-5136
    • George, J.T.1    Seminara, S.B.2
  • 53
    • 84878530524 scopus 로고    scopus 로고
    • Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism
    • George JT, Veldhuis JD, Tena-Sempere M, Millar RP & Anderson RA 2013 Exploring the pathophysiology of hypogonadism in men with type 2 diabetes: kisspeptin-10 stimulates serum testosterone and LH secretion in men with type 2 diabetes and mild biochemical hypogonadism. Clinical Endocrinology 79 100-104. (doi:10.1111/cen.12103)
    • (2013) Clinical Endocrinology , vol.79 , pp. 100-104
    • George, J.T.1    Veldhuis, J.D.2    Tena-Sempere, M.3    Millar, R.P.4    Anderson, R.A.5
  • 54
    • 84892857000 scopus 로고    scopus 로고
    • Glucocorticoid receptor-mediated regulation of Rfrp (GnIH) and Gpr147 (GnIH-R) synthesis in immortalized hypothalamic neurons
    • Gojska NM & Belsham DD 2014 Glucocorticoid receptor-mediated regulation of Rfrp (GnIH) and Gpr147 (GnIH-R) synthesis in immortalized hypothalamic neurons. Molecular and Cellular Endocrinology 384 23-31. (doi:10.1016/j.mce.2013.12.015)
    • (2014) Molecular and Cellular Endocrinology , vol.384 , pp. 23-31
    • Gojska, N.M.1    Belsham, D.D.2
  • 57
    • 0036285444 scopus 로고    scopus 로고
    • The neuroendocrinology of human puberty revisited
    • Grumbach MM 2002 The neuroendocrinology of human puberty revisited. Hormone Research 57(Suppl 2) 2-14. (doi:10.1159/000058094)
    • (2002) Hormone Research , vol.57 , pp. 2-14
    • Grumbach, M.M.1
  • 63
    • 0017167075 scopus 로고
    • Some effects of experimentally-induced diabetes on pituitary-testicular relationships in rats
    • Howland BE & Zebrowski EJ 1976 Some effects of experimentally-induced diabetes on pituitary-testicular relationships in rats. Hormone and Metabolic Research 8 465-469. (doi:10.1055/s-0028-1093597)
    • (1976) Hormone and Metabolic Research , vol.8 , pp. 465-469
    • Howland, B.E.1    Zebrowski, E.J.2
  • 64
    • 0018975333 scopus 로고
    • Pituitary response to gonadotropinreleasing hormone in diabetic male rats
    • Howland BE & Zebrowski EJ 1980 Pituitary response to gonadotropinreleasing hormone in diabetic male rats. Experientia 36 610-611. (doi:10.1007/BF01965832)
    • (1980) Experientia , vol.36 , pp. 610-611
    • Howland, B.E.1    Zebrowski, E.J.2
  • 65
    • 84904318063 scopus 로고    scopus 로고
    • Intratesticular action of kisspeptin in rhesus monkey (Macaca mulatta)
    • Irfan S, Ehmcke J, Wahab F, Shahab M & Schlatt S 2014 Intratesticular action of kisspeptin in rhesus monkey (Macaca mulatta). Andrologia 46 610-617. (doi:10.1111/and.12121)
    • (2014) Andrologia , vol.46 , pp. 610-617
    • Irfan, S.1    Ehmcke, J.2    Wahab, F.3    Shahab, M.4    Schlatt, S.5
  • 67
    • 54949141523 scopus 로고    scopus 로고
    • Decreased expression of kisspeptin mediates acute immune/inflammatory stress-induced suppression of gonadotropin secretion in female rat
    • Iwasa T, Matsuzaki T, Murakami M, Shimizu F, Kuwahara A, Yasui T & Irahara M 2008 Decreased expression of kisspeptin mediates acute immune/inflammatory stress-induced suppression of gonadotropin secretion in female rat. Journal of Endocrinological Investigation 31 656-659. (doi:10.1007/BF03345620)
    • (2008) Journal of Endocrinological Investigation , vol.31 , pp. 656-659
    • Iwasa, T.1    Matsuzaki, T.2    Murakami, M.3    Shimizu, F.4    Kuwahara, A.5    Yasui, T.6    Irahara, M.7
  • 71
    • 33751524344 scopus 로고    scopus 로고
    • Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat
    • Johnson MA, Tsutsui K & Fraley GS 2007 Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat. Hormones and Behavior 51 171-180. (doi:10.1016/j.yhbeh.2006.09.009)
    • (2007) Hormones and Behavior , vol.51 , pp. 171-180
    • Johnson, M.A.1    Tsutsui, K.2    Fraley, G.S.3
  • 72
    • 78650141967 scopus 로고    scopus 로고
    • Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats
    • Kaewwongse M, Takayanagi Y & Onaka T 2011 Effects of RFamide-related peptide (RFRP)-1 and RFRP-3 on oxytocin release and anxiety-related behaviour in rats. Journal of Neuroendocrinology 23 20-27. (doi:10.1111/j.1365-2826.2010.02077.x)
    • (2011) Journal of Neuroendocrinology , vol.23 , pp. 20-27
    • Kaewwongse, M.1    Takayanagi, Y.2    Onaka, T.3
  • 73
    • 11144297187 scopus 로고    scopus 로고
    • Galaninlike peptide in the brain: effects on feeding, energy metabolism and reproduction
    • Kageyama H, Takenoya F, Kita T, Hori T, Guan J-L & Shioda S 2005 Galaninlike peptide in the brain: effects on feeding, energy metabolism and reproduction. Regulatory Peptides 126 21-26. (doi:10.1016/j.regpep.2004.08.029)
    • (2005) Regulatory Peptides , vol.126 , pp. 21-26
    • Kageyama, H.1    Takenoya, F.2    Kita, T.3    Hori, T.4    Guan, J.-L.5    Shioda, S.6
  • 74
    • 75449148131 scopus 로고
    • Body weight and food intake as initiating factors for puberty in the rat
    • Kennedy GC & Mitra J 1963a Body weight and food intake as initiating factors for puberty in the rat. Journal of Physiology 166 408-418. (doi:10.1113/jphysiol.1963.sp007112)
    • (1963) Journal of Physiology , vol.166 , pp. 408-418
    • Kennedy, G.C.1    Mitra, J.2
  • 75
    • 0000527354 scopus 로고
    • Hypothalamic control of energy balance and the reproductive cycle in the rat
    • Kennedy GC & Mitra J 1963b Hypothalamic control of energy balance and the reproductive cycle in the rat. Journal of Physiology 166 395-407. (doi:10.1113/jphysiol.1963.sp007111)
    • (1963) Journal of Physiology , vol.166 , pp. 395-407
    • Kennedy, G.C.1    Mitra, J.2
  • 76
    • 77957277596 scopus 로고    scopus 로고
    • Kisspeptin directly regulates neuropeptide Y synthesis and secretion via the ERK1/2 and p38 mitogen-activated protein kinase signaling pathways in NPY-secreting hypothalamic neurons
    • Kim GL, Dhillon SS & Belsham DD 2010 Kisspeptin directly regulates neuropeptide Y synthesis and secretion via the ERK1/2 and p38 mitogen-activated protein kinase signaling pathways in NPY-secreting hypothalamic neurons. Endocrinology 151 5038-5047. (doi:10.1210/en.2010-0521)
    • (2010) Endocrinology , vol.151 , pp. 5038-5047
    • Kim, G.L.1    Dhillon, S.S.2    Belsham, D.D.3
  • 77
    • 0141794168 scopus 로고    scopus 로고
    • A rat model for the energetic regulation of gonadotropin secretion: role of the glucosesensing mechanism in the brain
    • Kinoshita M, Moriyama R, Tsukamura H & Maeda K-I 2003 A rat model for the energetic regulation of gonadotropin secretion: role of the glucosesensing mechanism in the brain. Domestic Animal Endocrinology 25 109-120. (doi:10.1016/S0739-7240(03)00050-X)
    • (2003) Domestic Animal Endocrinology , vol.25 , pp. 109-120
    • Kinoshita, M.1    Moriyama, R.2    Tsukamura, H.3    Maeda, K.-I.4
  • 78
    • 57749201616 scopus 로고    scopus 로고
    • Down-regulation of hypothalamic kisspeptin and its receptor, Kiss1r, mRNA expression is associated with stress-induced suppression of luteinising hormone secretion in the female rat
    • Kinsey-Jones JS, Li XF, Knox AMI, Wilkinson ES, Zhu XL, Chaudhary AA, Milligan SR, Lightman SL & O'Byrne KT 2009 Down-regulation of hypothalamic kisspeptin and its receptor, Kiss1r, mRNA expression is associated with stress-induced suppression of luteinising hormone secretion in the female rat. Journal of Neuroendocrinology 21 20-29. (doi:10.1111/j.1365-2826.2008.01807.x)
    • (2009) Journal of Neuroendocrinology , vol.21 , pp. 20-29
    • Kinsey-Jones, J.S.1    Li, X.F.2    Knox, A.M.I.3    Wilkinson, E.S.4    Zhu, X.L.5    Chaudhary, A.A.6    Milligan, S.R.7    Lightman, S.L.8    O'Byrne, K.T.9
  • 79
    • 84934444157 scopus 로고    scopus 로고
    • Circadian regulation of kisspeptin in female reproductive functioning
    • Kriegsfeld LJ 2013 Circadian regulation of kisspeptin in female reproductive functioning. Advances in Experimental Medicine and Biology 784 385-410.
    • (2013) Advances in Experimental Medicine and Biology , vol.784 , pp. 385-410
    • Kriegsfeld, L.J.1
  • 83
    • 0024389275 scopus 로고
    • Dose response effects of pulsatile GnRH administration on restoration of pituitary GnRH receptors and pulsatile LH secretion during lactation
    • Lee LR, Paul SJ & Smith MS 1989 Dose response effects of pulsatile GnRH administration on restoration of pituitary GnRH receptors and pulsatile LH secretion during lactation. Neuroendocrinology 49 664-668. (doi:10.1159/000125185)
    • (1989) Neuroendocrinology , vol.49 , pp. 664-668
    • Lee, L.R.1    Paul, S.J.2    Smith, M.S.3
  • 86
    • 45249113948 scopus 로고    scopus 로고
    • Central and peripheral administration of kisspeptin activates gonadotropin but not somatotropin secretion in prepubertal gilts
    • Lents CA, Heidorn NL, Barb CR & Ford JJ 2008 Central and peripheral administration of kisspeptin activates gonadotropin but not somatotropin secretion in prepubertal gilts. Reproduction 135 879-887. (doi:10.1530/REP-07-0502)
    • (2008) Reproduction , vol.135 , pp. 879-887
    • Lents, C.A.1    Heidorn, N.L.2    Barb, C.R.3    Ford, J.J.4
  • 87
    • 0030957954 scopus 로고    scopus 로고
    • Neuropeptide Y Y1-receptor stimulation is required for physiological amplification of preovulatory luteinizing hormone surges
    • Leupen SM, Besecke LM & Levine JE 1997 Neuropeptide Y Y1-receptor stimulation is required for physiological amplification of preovulatory luteinizing hormone surges. Endocrinology 138 2735-2739.
    • (1997) Endocrinology , vol.138 , pp. 2735-2739
    • Leupen, S.M.1    Besecke, L.M.2    Levine, J.E.3
  • 88
    • 84864135265 scopus 로고    scopus 로고
    • Gonadotropin-inhibitory hormone (GnIH) and its receptor in the female pig: cDNA cloning, expression in tissues and expression pattern in the reproductive axis during the estrous cycle
    • Li X, Su J, Lei Z, Zhao Y, Jin M, Fang R, Zheng L & Jiao Y 2012 Gonadotropin-inhibitory hormone (GnIH) and its receptor in the female pig: cDNA cloning, expression in tissues and expression pattern in the reproductive axis during the estrous cycle. Peptides 36 176-185. (doi:10.1016/j.peptides.2012.05.008)
    • (2012) Peptides , vol.36 , pp. 176-185
    • Li, X.1    Su, J.2    Lei, Z.3    Zhao, Y.4    Jin, M.5    Fang, R.6    Zheng, L.7    Jiao, Y.8
  • 89
    • 0015302342 scopus 로고
    • Serum levels of prolactin, luteinizing hormone, and follicle stimulating hormone during pregnancy in the rat
    • Linkie DM & Niswender GD 1972 Serum levels of prolactin, luteinizing hormone, and follicle stimulating hormone during pregnancy in the rat. Endocrinology 90 632-637. (doi:10.1210/endo-90-3-632)
    • (1972) Endocrinology , vol.90 , pp. 632-637
    • Linkie, D.M.1    Niswender, G.D.2
  • 90
    • 46349095554 scopus 로고    scopus 로고
    • Small-conductance calcium-activated potassium channels control excitability and firing dynamics in gonadotropinreleasing hormone (GnRH) neurons
    • Liu X & Herbison AE 2008 Small-conductance calcium-activated potassium channels control excitability and firing dynamics in gonadotropinreleasing hormone (GnRH) neurons. Endocrinology 149 3598-3604. (doi:10.1210/en.2007-1631)
    • (2008) Endocrinology , vol.149 , pp. 3598-3604
    • Liu, X.1    Herbison, A.E.2
  • 91
    • 50449087725 scopus 로고    scopus 로고
    • Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels
    • Liu X, Lee K & Herbison AE 2008 Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels. Endocrinology 149 4605-4614. (doi:10.1210/en.2008-0321)
    • (2008) Endocrinology , vol.149 , pp. 4605-4614
    • Liu, X.1    Lee, K.2    Herbison, A.E.3
  • 92
    • 84891396402 scopus 로고    scopus 로고
    • Lactational anovulation in mice results from a selective loss of kisspeptin input to GnRH neurons
    • Liu X, Brown RSE, Herbison AE & Grattan DR 2014 Lactational anovulation in mice results from a selective loss of kisspeptin input to GnRH neurons. Endocrinology 155 193-203. (doi:10.1210/en.2013-1621)
    • (2014) Endocrinology , vol.155 , pp. 193-203
    • Liu, X.1    Brown, R.S.E.2    Herbison, A.E.3    Grattan, D.R.4
  • 93
    • 84864300557 scopus 로고    scopus 로고
    • Lipopolysaccharide injection induces rapid decrease of hypothalamic GnRH mRNA and peptide, but does not affect GnIH in zebra finches
    • Lopes PC, Wingfield JC & Bentley GE 2012 Lipopolysaccharide injection induces rapid decrease of hypothalamic GnRH mRNA and peptide, but does not affect GnIH in zebra finches. Hormones and Behavior 62 173-179. (doi:10.1016/j.yhbeh.2012.06.007)
    • (2012) Hormones and Behavior , vol.62 , pp. 173-179
    • Lopes, P.C.1    Wingfield, J.C.2    Bentley, G.E.3
  • 94
    • 79956308808 scopus 로고    scopus 로고
    • Molecular mapping of the neural pathways linking leptin to the neuroendocrine reproductive axis
    • Louis GW, Greenwald-Yarnell M, Phillips R, Coolen LM, Lehman MN & Myers MG 2011 Molecular mapping of the neural pathways linking leptin to the neuroendocrine reproductive axis. Endocrinology 152 2302-2310. (doi:10.1210/en.2011-0096)
    • (2011) Endocrinology , vol.152 , pp. 2302-2310
    • Louis, G.W.1    Greenwald-Yarnell, M.2    Phillips, R.3    Coolen, L.M.4    Lehman, M.N.5    Myers, M.G.6
  • 95
    • 34748840772 scopus 로고    scopus 로고
    • Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line
    • Luque RM, Kineman RD & Tena-Sempere M 2007 Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line. Endocrinology 148 4601-4611. (doi:10.1210/en.2007-0500)
    • (2007) Endocrinology , vol.148 , pp. 4601-4611
    • Luque, R.M.1    Kineman, R.D.2    Tena-Sempere, M.3
  • 96
    • 0020554633 scopus 로고
    • Reproductive consequences of food restriction at low temperature in lines of mice divergently selected for thermoregulatory nesting
    • Marsteller FA & Lynch CB 1983 Reproductive consequences of food restriction at low temperature in lines of mice divergently selected for thermoregulatory nesting. Behavior Genetics 13 397-410. (doi:10.1007/BF01065777)
    • (1983) Behavior Genetics , vol.13 , pp. 397-410
    • Marsteller, F.A.1    Lynch, C.B.2
  • 97
    • 84899485312 scopus 로고    scopus 로고
    • Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone
    • Martin C, Navarro VM, Simavli S, Vong L, Carroll RS, Lowell BB & Kaiser UB 2014 Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone. Journal of Neuroscience 34 6047-6056. (doi:10.1523/JNEUROSCI.3003-13.2014)
    • (2014) Journal of Neuroscience , vol.34 , pp. 6047-6056
    • Martin, C.1    Navarro, V.M.2    Simavli, S.3    Vong, L.4    Carroll, R.S.5    Lowell, B.B.6    Kaiser, U.B.7
  • 100
    • 77951975331 scopus 로고    scopus 로고
    • A functional neuropeptide system in vertebrate gonads: gonadotropin-inhibitory hormone and its receptor in testes of field-caught house sparrow (Passer domesticus)
    • McGuire NL & Bentley GE 2010 A functional neuropeptide system in vertebrate gonads: gonadotropin-inhibitory hormone and its receptor in testes of field-caught house sparrow (Passer domesticus). General and Comparative Endocrinology 166 565-572. (doi:10.1016/j.ygcen.2010.01.010)
    • (2010) General and Comparative Endocrinology , vol.166 , pp. 565-572
    • McGuire, N.L.1    Bentley, G.E.2
  • 102
    • 0016711634 scopus 로고
    • Effects of various feeding regimens and photoperiod or pinealectomy on ovulation in the hamster
    • Morin LP 1975 Effects of various feeding regimens and photoperiod or pinealectomy on ovulation in the hamster. Biology of Reproduction 13 99-103. (doi:10.1095/biolreprod13.1.99)
    • (1975) Biology of Reproduction , vol.13 , pp. 99-103
    • Morin, L.P.1
  • 103
    • 0015739589 scopus 로고
    • Serum luteinizing hormone, prolactin and progesterone levels during pregnancy in the rat
    • Morishige WK, Pepe GJ & Rothchild I 1973 Serum luteinizing hormone, prolactin and progesterone levels during pregnancy in the rat. Endocrinology 92 1527-1530. (doi:10.1210/endo-92-5-1527)
    • (1973) Endocrinology , vol.92 , pp. 1527-1530
    • Morishige, W.K.1    Pepe, G.J.2    Rothchild, I.3
  • 105
    • 0031051499 scopus 로고    scopus 로고
    • Leptin treatment rescues the sterility of genetically obese ob/ob males
    • Mounzih K, Lu R & Chehab FF 1997 Leptin treatment rescues the sterility of genetically obese ob/ob males. Endocrinology 138 1190-1193.
    • (1997) Endocrinology , vol.138 , pp. 1190-1193
    • Mounzih, K.1    Lu, R.2    Chehab, F.F.3
  • 109
    • 84926610080 scopus 로고    scopus 로고
    • Cross-talk between reproduction and energy homeostasis: central impact of estrogens, leptin and kisspeptin signaling
    • Nestor CC, Kelly MJ & Rønnekleiv OK 2014 Cross-talk between reproduction and energy homeostasis: central impact of estrogens, leptin and kisspeptin signaling. Hormone Molecular Biology and Clinical Investigation 17 109-128. (doi:10.1515/hmbci-2013-0050)
    • (2014) Hormone Molecular Biology and Clinical Investigation , vol.17 , pp. 109-128
    • Nestor, C.C.1    Kelly, M.J.2    Rønnekleiv, O.K.3
  • 110
    • 84919773873 scopus 로고    scopus 로고
    • Structural and functional divergence of gonadotropin-inhibitory hormone from jawless fish to mammals
    • Ogawa S & Parhar IS 2014 Structural and functional divergence of gonadotropin-inhibitory hormone from jawless fish to mammals. Frontiers in Endocrinology 5 177. (doi:10.3389/fendo.2014.00177)
    • (2014) Frontiers in Endocrinology , vol.5 , pp. 177
    • Ogawa, S.1    Parhar, I.S.2
  • 111
    • 0018876099 scopus 로고
    • Increase in oxytocin secretion at ejaculation in male
    • Ogawa S, Kudo S, Kitsunai Y & Fukuchi S 1980 Increase in oxytocin secretion at ejaculation in male. Clinical Endocrinology 13 95-97. (doi:10.1111/j.1365-2265.1980.tb01027.x)
    • (1980) Clinical Endocrinology , vol.13 , pp. 95-97
    • Ogawa, S.1    Kudo, S.2    Kitsunai, Y.3    Fukuchi, S.4
  • 115
    • 84905907540 scopus 로고    scopus 로고
    • Review: evolution of GnIH and related peptides structure and function in the chordates
    • Osugi T, Ubuka T & Tsutsui K 2014 Review: evolution of GnIH and related peptides structure and function in the chordates. Frontiers in Neuroscience 8 255. (doi:10.3389/fnins.2014.00255)
    • (2014) Frontiers in Neuroscience , vol.8 , pp. 255
    • Osugi, T.1    Ubuka, T.2    Tsutsui, K.3
  • 116
    • 0026095990 scopus 로고
    • Restoration of pulsatile luteinizing hormone secretion after fasting in rhesus monkeys (Macaca mulatta): dependence on size of the refeed meal
    • Parfitt DB, Church KR & Cameron JL 1991 Restoration of pulsatile luteinizing hormone secretion after fasting in rhesus monkeys (Macaca mulatta): dependence on size of the refeed meal. Endocrinology 129 749-756. (doi:10.1210/endo-129-2-749)
    • (1991) Endocrinology , vol.129 , pp. 749-756
    • Parfitt, D.B.1    Church, K.R.2    Cameron, J.L.3
  • 117
    • 3843063447 scopus 로고    scopus 로고
    • Laser-captured single digoxigeninlabeled neurons of gonadotropin-releasing hormone types reveal a novel G protein-coupled receptor (Gpr54) during maturation in cichlid fish
    • Parhar IS, Ogawa S & Sakuma Y 2004 Laser-captured single digoxigeninlabeled neurons of gonadotropin-releasing hormone types reveal a novel G protein-coupled receptor (Gpr54) during maturation in cichlid fish. Endocrinology 145 3613-3618. (doi:10.1210/en.2004-0395)
    • (2004) Endocrinology , vol.145 , pp. 3613-3618
    • Parhar, I.S.1    Ogawa, S.2    Sakuma, Y.3
  • 118
    • 84946049543 scopus 로고    scopus 로고
    • Effect of gonadotropin inhibitory hormone (GnIH) secretion on post-ejaculatory refractory period: a hypothesis
    • Pazhoohi F & Saied Salehi M 2013 Effect of gonadotropin inhibitory hormone (GnIH) secretion on post-ejaculatory refractory period: a hypothesis. Hypothesis 11. (doi:10.5779/hypothesis.v11i1.286)
    • (2013) Hypothesis , pp. 11
    • Pazhoohi, F.1    Saied Salehi, M.2
  • 119
    • 0020819342 scopus 로고
    • Foraging effort, food intake, fat deposition and puberty in female mice
    • Perrigo G & Bronson FH 1983 Foraging effort, food intake, fat deposition and puberty in female mice. Biology of Reproduction 29 455-463. (doi:10.1095/biolreprod29.2.455)
    • (1983) Biology of Reproduction , vol.29 , pp. 455-463
    • Perrigo, G.1    Bronson, F.H.2
  • 120
    • 41549121999 scopus 로고    scopus 로고
    • Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol
    • Pielecka-Fortuna J, Chu Z & Moenter SM 2008 Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology 149 1979-1986. (doi:10.1210/en.2007-1365)
    • (2008) Endocrinology , vol.149 , pp. 1979-1986
    • Pielecka-Fortuna, J.1    Chu, Z.2    Moenter, S.M.3
  • 122
    • 77950268600 scopus 로고    scopus 로고
    • Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications
    • Pineda R, Garcia-Galiano D, Sanchez-Garrido MA, Romero M, Ruiz-Pino F, Aguilar E, Dijcks FA, Blomenröhr M, Pinilla L, van Noort PI et al. 2010b Characterization of the potent gonadotropin-releasing activity of RF9, a selective antagonist of RF-amide-related peptides and neuropeptide FF receptors: physiological and pharmacological implications. Endocrinology 151 1902-1913. (doi:10.1210/en.2009-1259)
    • (2010) Endocrinology , vol.151 , pp. 1902-1913
    • Pineda, R.1    Garcia-Galiano, D.2    Sanchez-Garrido, M.A.3    Romero, M.4    Ruiz-Pino, F.5    Aguilar, E.6    Dijcks, F.A.7    Blomenröhr, M.8    Pinilla, L.9    van Noort, P.I.10
  • 123
    • 84864067222 scopus 로고    scopus 로고
    • Kisspeptins and reproduction: physiological roles and regulatory mechanisms
    • Pinilla L, Aguilar E, Dieguez C, Millar RP & Tena-Sempere M 2012 Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiological Reviews 92 1235-1316. (doi:10.1152/physrev.00037.2010)
    • (2012) Physiological Reviews , vol.92 , pp. 1235-1316
    • Pinilla, L.1    Aguilar, E.2    Dieguez, C.3    Millar, R.P.4    Tena-Sempere, M.5
  • 124
    • 84923060590 scopus 로고    scopus 로고
    • Examination of the Influence of leptin and acute metabolic challenge on RFRP-3 neurons of mice in development and adulthood
    • Poling MC, Shieh MP, Munaganuru N, Luo E & Kauffman AS 2014 Examination of the Influence of leptin and acute metabolic challenge on RFRP-3 neurons of mice in development and adulthood. Neuroendocrinology. (doi:10.1159/000369276)
    • (2014) Neuroendocrinology
    • Poling, M.C.1    Shieh, M.P.2    Munaganuru, N.3    Luo, E.4    Kauffman, A.S.5
  • 125
    • 0035695028 scopus 로고    scopus 로고
    • Neuroendocrine effects of leptin
    • Pralong FP & Gaillard RC 2001 Neuroendocrine effects of leptin. Pituitary 4 25-32. (doi:10.1023/A:1012930609563)
    • (2001) Pituitary , vol.4 , pp. 25-32
    • Pralong, F.P.1    Gaillard, R.C.2
  • 127
    • 67650770048 scopus 로고    scopus 로고
    • Projections of RFamide-related peptide-3 neurones inthe ovine hypothalamus,with special reference to regions regulating energy balance and reproduction
    • Qi Y, Oldfield BJ & Clarke IJ 2009 Projections of RFamide-related peptide-3 neurones inthe ovine hypothalamus,with special reference to regions regulating energy balance and reproduction. Journal of Neuroendocrinology 21 690-697. (doi:10.1111/j.1365-2826.2009.01886.x)
    • (2009) Journal of Neuroendocrinology , vol.21 , pp. 690-697
    • Qi, Y.1    Oldfield, B.J.2    Clarke, I.J.3
  • 128
  • 129
    • 36849001888 scopus 로고    scopus 로고
    • Expression of a functional g protein-coupled receptor 54-kisspeptin autoregulatory system in hypothalamic gonadotropinreleasing hormone neurons
    • Quaynor S, Hu L, Leung PK, Feng H, Mores N, Krsmanovic LZ & Catt KJ 2007 Expression of a functional g protein-coupled receptor 54-kisspeptin autoregulatory system in hypothalamic gonadotropinreleasing hormone neurons. Molecular Endocrinology 21 3062-3070. (doi:10.1210/me.2007-0207)
    • (2007) Molecular Endocrinology , vol.21 , pp. 3062-3070
    • Quaynor, S.1    Hu, L.2    Leung, P.K.3    Feng, H.4    Mores, N.5    Krsmanovic, L.Z.6    Catt, K.J.7
  • 131
    • 79953209692 scopus 로고    scopus 로고
    • Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice
    • Quennell JH, Howell CS, Roa J, Augustine RA, Grattan DR & Anderson GM 2011 Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice. Endocrinology 152 1541-1550. (doi:10.1210/en.2010-1100)
    • (2011) Endocrinology , vol.152 , pp. 1541-1550
    • Quennell, J.H.1    Howell, C.S.2    Roa, J.3    Augustine, R.A.4    Grattan, D.R.5    Anderson, G.M.6
  • 132
    • 84916603593 scopus 로고    scopus 로고
    • Chemical identity of hypothalamic neurons engaged by leptin in reproductive control
    • Ratra DV & Elias CF 2014 Chemical identity of hypothalamic neurons engaged by leptin in reproductive control. Journal of Chemical Neuroanatomy 61-62 233-238.
    • (2014) Journal of Chemical Neuroanatomy , vol.61-62 , pp. 233-238
    • Ratra, D.V.1    Elias, C.F.2
  • 135
    • 84897475747 scopus 로고    scopus 로고
    • Evidence that hypothalamic RFamide related peptide-3 neurones are not leptin-responsive in mice and rats
    • Rizwan MZ, Harbid AA, Inglis MA, Quennell JH & Anderson GM 2014 Evidence that hypothalamic RFamide related peptide-3 neurones are not leptin-responsive in mice and rats. Journal of Neuroendocrinology 26 247-257. (doi:10.1111/jne.12140)
    • (2014) Journal of Neuroendocrinology , vol.26 , pp. 247-257
    • Rizwan, M.Z.1    Harbid, A.A.2    Inglis, M.A.3    Quennell, J.H.4    Anderson, G.M.5
  • 136
    • 84914133446 scopus 로고    scopus 로고
    • Connecting metabolism and reproduction: roles of central energy sensors and key molecular mediators
    • Roa J & Tena-Sempere M 2014 Connecting metabolism and reproduction: roles of central energy sensors and key molecular mediators. Molecular and Cellular Endocrinology 397 4-14. (doi:10.1016/j.mce.2014.09.027)
    • (2014) Molecular and Cellular Endocrinology , vol.397 , pp. 4-14
    • Roa, J.1    Tena-Sempere, M.2
  • 138
    • 0035225243 scopus 로고    scopus 로고
    • Brain preparations for maternity -adaptive changes in behavioral and neuroendocrine systems during pregnancyand lactation. Anoverview
    • Russell JA, Douglas AJ & Ingram CD 2001 Brain preparations for maternity -adaptive changes in behavioral and neuroendocrine systems during pregnancyand lactation. Anoverview. Progress in Brain Research1331-38.
    • (2001) Progress in Brain Research , pp. 1331-1338
    • Russell, J.A.1    Douglas, A.J.2    Ingram, C.D.3
  • 140
    • 84883374084 scopus 로고    scopus 로고
    • Metabolic control of puberty: roles of leptin and kisspeptins
    • Sanchez-Garrido MA & Tena-Sempere M 2013 Metabolic control of puberty: roles of leptin and kisspeptins. Hormones and Behavior 64 187-194. (doi:10.1016/j.yhbeh.2013.01.014)
    • (2013) Hormones and Behavior , vol.64 , pp. 187-194
    • Sanchez-Garrido, M.A.1    Tena-Sempere, M.2
  • 141
    • 71949109633 scopus 로고    scopus 로고
    • Effect of RF-amiderelated peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes
    • Sari IP, Rao A, Smith JT, Tilbrook AJ & Clarke IJ 2009 Effect of RF-amiderelated peptide-3 on luteinizing hormone and follicle-stimulating hormone synthesis and secretion in ovine pituitary gonadotropes. Endocrinology 150 5549-5556. (doi:10.1210/en.2009-0775)
    • (2009) Endocrinology , vol.150 , pp. 5549-5556
    • Sari, I.P.1    Rao, A.2    Smith, J.T.3    Tilbrook, A.J.4    Clarke, I.J.5
  • 142
    • 0019256663 scopus 로고
    • Effect of neonatal undernutrition on serum follicle-stimulating hormone levels and ovarian development in the female rat
    • Schenck PE, Slob AK, Uilenbroek JT & van der Werff ten Bosch JJ 1980 Effect of neonatal undernutrition on serum follicle-stimulating hormone levels and ovarian development in the female rat. British Journal of Nutrition 44 179-182. (doi:10.1079/BJN19800025)
    • (1980) British Journal of Nutrition , vol.44 , pp. 179-182
    • Schenck, P.E.1    Slob, A.K.2    Uilenbroek, J.T.3    van der Werff ten Bosch, J.J.4
  • 143
    • 15444364846 scopus 로고    scopus 로고
    • New gatekeepers of reproduction: GPR54 and its cognate ligand, KiSS-1
    • Seminara SB & Kaiser UB 2005 New gatekeepers of reproduction: GPR54 and its cognate ligand, KiSS-1. Endocrinology 146 1686-1688. (doi:10.1210/en.2005-0070)
    • (2005) Endocrinology , vol.146 , pp. 1686-1688
    • Seminara, S.B.1    Kaiser, U.B.2
  • 145
    • 0030889371 scopus 로고    scopus 로고
    • Effect of diabetes mellitus upon male reproductive function
    • Sexton WJ & Jarow JP 1997 Effect of diabetes mellitus upon male reproductive function. Urology 49 508-513. (doi:10.1016/S0090-4295(96)00573-0)
    • (1997) Urology , vol.49 , pp. 508-513
    • Sexton, W.J.1    Jarow, J.P.2
  • 146
    • 0030851180 scopus 로고    scopus 로고
    • Fasting-induced suppression of hypothalamic-pituitary-gonadal axis in the adult rhesus monkey: evidence for involvement of excitatory amino acid neurotransmitters
    • Shahab M, Zaman W, Bashir K & Arslan M 1997 Fasting-induced suppression of hypothalamic-pituitary-gonadal axis in the adult rhesus monkey: evidence for involvement of excitatory amino acid neurotransmitters. Life Sciences 61 1293-1300. (doi:10.1016/S0024-3205(97)00674-7)
    • (1997) Life Sciences , vol.61 , pp. 1293-1300
    • Shahab, M.1    Zaman, W.2    Bashir, K.3    Arslan, M.4
  • 147
    • 13844317911 scopus 로고    scopus 로고
    • Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates
    • Shahab M, Mastronardi C, Seminara SB, Crowley WF, Ojeda SR & Plant TM 2005 Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates. PNAS 102 2129-2134. (doi:10.1073/pnas.0409822102)
    • (2005) PNAS , vol.102 , pp. 2129-2134
    • Shahab, M.1    Mastronardi, C.2    Seminara, S.B.3    Crowley, W.F.4    Ojeda, S.R.5    Plant, T.M.6
  • 148
    • 0017875979 scopus 로고
    • A comparison of pituitary responsiveness to luteinizing hormone-releasing hormone during lactation and the estrous cycle of the rat
    • Smith MS 1978 A comparison of pituitary responsiveness to luteinizing hormone-releasing hormone during lactation and the estrous cycle of the rat. Endocrinology 102 114-120. (doi:10.1210/endo-102-1-114)
    • (1978) Endocrinology , vol.102 , pp. 114-120
    • Smith, M.S.1
  • 149
    • 57849108455 scopus 로고    scopus 로고
    • Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: comparative aspects
    • Smith JT 2009 Sex steroid control of hypothalamic Kiss1 expression in sheep and rodents: comparative aspects. Peptides 30 94-102. (doi:10.1016/j.peptides.2008.08.013)
    • (2009) Peptides , vol.30 , pp. 94-102
    • Smith, J.T.1
  • 150
    • 84863778191 scopus 로고    scopus 로고
    • The role of kisspeptin and gonadotropin inhibitory hormone in the seasonal regulation of reproduction in sheep
    • Smith JT 2012 The role of kisspeptin and gonadotropin inhibitory hormone in the seasonal regulation of reproduction in sheep. Domestic Animal Endocrinology 43 75-84. (doi:10.1016/j.domaniend.2011.11.003)
    • (2012) Domestic Animal Endocrinology , vol.43 , pp. 75-84
    • Smith, J.T.1
  • 152
    • 77950620742 scopus 로고    scopus 로고
    • Gonadotropin inhibitory hormone function in mammals
    • Smith JT & Clarke IJ 2010 Gonadotropin inhibitory hormone function in mammals. Trends in Endocrinology and Metabolism 21 255-260. (doi:10.1016/j.tem.2009.11.010)
    • (2010) Trends in Endocrinology and Metabolism , vol.21 , pp. 255-260
    • Smith, J.T.1    Clarke, I.J.2
  • 153
    • 0036334426 scopus 로고    scopus 로고
    • Integration of the regulation of reproductive function and energy balance: lactation as a model
    • Smith MS & Grove KL 2002 Integration of the regulation of reproductive function and energy balance: lactation as a model. Frontiers in Endocrinology 23 225-256.
    • (2002) Frontiers in Endocrinology , vol.23 , pp. 225-256
    • Smith, M.S.1    Grove, K.L.2
  • 155
    • 33847008349 scopus 로고    scopus 로고
    • KiSS-1messenger ribonucleic acid expressioninthehypothalamusof theewe is regulated bysex steroids and season
    • Smith JT, Clay CM, Caraty A & Clarke IJ 2007 KiSS-1messenger ribonucleic acid expressioninthehypothalamusof theewe is regulated bysex steroids and season. Endocrinology 148 1150-1157. (doi:10.1210/en.2006-1435)
    • (2007) Endocrinology , vol.148 , pp. 1150-1157
    • Smith, J.T.1    Clay, C.M.2    Caraty, A.3    Clarke, I.J.4
  • 156
    • 54349094522 scopus 로고    scopus 로고
    • Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep
    • Smith JT, Coolen LM, Kriegsfeld LJ, Sari IP, Jaafarzadehshirazi MR, Maltby M, Bateman K, Goodman RL, Tilbrook AJ, Ubuka T et al. 2008 Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep. Endocrinology 149 5770-5782. (doi:10.1210/en.2008-0581)
    • (2008) Endocrinology , vol.149 , pp. 5770-5782
    • Smith, J.T.1    Coolen, L.M.2    Kriegsfeld, L.J.3    Sari, I.P.4    Jaafarzadehshirazi, M.R.5    Maltby, M.6    Bateman, K.7    Goodman, R.L.8    Tilbrook, A.J.9    Ubuka, T.10
  • 157
    • 78649496535 scopus 로고    scopus 로고
    • The neuroendocrine basis of lactationinduced suppression of GnRH: role of kisspeptin and leptin
    • Smith MS, True C & Grove KL 2010a The neuroendocrine basis of lactationinduced suppression of GnRH: role of kisspeptin and leptin. Brain Research 1364 139-152. (doi:10.1016/j.brainres.2010.08.038)
    • (2010) Brain Research , vol.1364 , pp. 139-152
    • Smith, M.S.1    True, C.2    Grove, K.L.3
  • 158
    • 77957558583 scopus 로고    scopus 로고
    • Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate
    • Smith JT, Shahab M, Pereira A, Pau K-YF & Clarke IJ 2010b Hypothalamic expression of KISS1 and gonadotropin inhibitory hormone genes during the menstrual cycle of a non-human primate. Biology of Reproduction 83 568-577. (doi:10.1095/biolreprod.110.085407)
    • (2010) Biology of Reproduction , vol.83 , pp. 568-577
    • Smith, J.T.1    Shahab, M.2    Pereira, A.3    Pau, K.-Y.F.4    Clarke, I.J.5
  • 159
    • 0021990046 scopus 로고
    • Altered hypothalamic-pituitary function in the adult female rat with streptozotocin-induced diabetes
    • Spindler-Vomachka M & Johnson DC 1985 Altered hypothalamic-pituitary function in the adult female rat with streptozotocin-induced diabetes. Diabetologia 28 38-44. (doi:10.1007/BF00276998)
    • (1985) Diabetologia , vol.28 , pp. 38-44
    • Spindler-Vomachka, M.1    Johnson, D.C.2
  • 160
    • 79952911323 scopus 로고    scopus 로고
    • Centrally injected kisspeptin reduces food intake by increasing meal intervals in mice
    • Stengel A, Wang L, Goebel-Stengel M & Taché Y 2011 Centrally injected kisspeptin reduces food intake by increasing meal intervals in mice. Neuroreport 22 253-257. (doi:10.1097/WNR.0b013e32834558df)
    • (2011) Neuroreport , vol.22 , pp. 253-257
    • Stengel, A.1    Wang, L.2    Goebel-Stengel, M.3    Taché, Y.4
  • 162
    • 21544441490 scopus 로고    scopus 로고
    • Gonadotropin-inhibiting hormone stimulates feeding behavior in chicks
    • Tachibana T, Sato M, Takahashi H, Ukena K, Tsutsui K & Furuse M 2005 Gonadotropin-inhibiting hormone stimulates feeding behavior in chicks. Brain Research 1050 94-100. (doi:10.1016/j.brainres.2005.05.035)
    • (2005) Brain Research , vol.1050 , pp. 94-100
    • Tachibana, T.1    Sato, M.2    Takahashi, H.3    Ukena, K.4    Tsutsui, K.5    Furuse, M.6
  • 164
    • 84890546876 scopus 로고    scopus 로고
    • Interaction between energy homeostasis and reproduction: central effects of leptin and ghrelin on the reproductive axis
    • Tena-Sempere M 2013 Interaction between energy homeostasis and reproduction: central effects of leptin and ghrelin on the reproductive axis. Hormone and Metabolic Research 45 919-927. (doi:10.1055/s-0033-1355399)
    • (2013) Hormone and Metabolic Research , vol.45 , pp. 919-927
    • Tena-Sempere, M.1
  • 165
    • 84855243037 scopus 로고    scopus 로고
    • Comparative insights of the kisspeptin/kisspeptin receptor system: lessons from non-mammalian vertebrates
    • Tena-Sempere M, Felip A, Gómez A, Zanuy S & Carrillo M 2012 Comparative insights of the kisspeptin/kisspeptin receptor system: lessons from non-mammalian vertebrates. General and Comparative Endocrinology 175 234-243. (doi:10.1016/j.ygcen.2011.11.015)
    • (2012) General and Comparative Endocrinology , vol.175 , pp. 234-243
    • Tena-Sempere, M.1    Felip, A.2    Gómez, A.3    Zanuy, S.4    Carrillo, M.5
  • 166
    • 0035112245 scopus 로고    scopus 로고
    • Neurobiological mechanisms of the onset of puberty in primates
    • Terasawa E & Fernandez DL 2001 Neurobiological mechanisms of the onset of puberty in primates. Endocrine Reviews 22 111-151.
    • (2001) Endocrine Reviews , vol.22 , pp. 111-151
    • Terasawa, E.1    Fernandez, D.L.2
  • 167
    • 84859415932 scopus 로고    scopus 로고
    • Body weight impact on puberty: effects of high-calorie diet on puberty onset in female rhesus monkeys
    • Terasawa E, Kurian JR, Keen KL, Shiel NA, Colman RJ & Capuano SV 2012 Body weight impact on puberty: effects of high-calorie diet on puberty onset in female rhesus monkeys. Endocrinology 153 1696-1705. (doi:10.1210/en.2011-1970)
    • (2012) Endocrinology , vol.153 , pp. 1696-1705
    • Terasawa, E.1    Kurian, J.R.2    Keen, K.L.3    Shiel, N.A.4    Colman, R.J.5    Capuano, S.V.6
  • 171
    • 84880655267 scopus 로고    scopus 로고
    • Cocaine- and amphetamineregulated transcript is a potent stimulator of GnRH and kisspeptin cells and may contribute to negative energy balance-induced reproductive inhibition in females
    • True C, Verma S, Grove KL & Smith MS 2013 Cocaine- and amphetamineregulated transcript is a potent stimulator of GnRH and kisspeptin cells and may contribute to negative energy balance-induced reproductive inhibition in females. Endocrinology 154 2821-2832. (doi:10.1210/en.2013-1156)
    • (2013) Endocrinology , vol.154 , pp. 2821-2832
    • True, C.1    Verma, S.2    Grove, K.L.3    Smith, M.S.4
  • 174
    • 37549002536 scopus 로고    scopus 로고
    • Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and -II neurons in European starling brain
    • Ubuka T, Kim S, Huang Y, Reid J, Jiang J, Osugi T, Chowdhury VS, Tsutsui K & Bentley GE 2008 Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and -II neurons in European starling brain. Endocrinology 149 268-278. (doi:10.1210/en.2007-0983)
    • (2008) Endocrinology , vol.149 , pp. 268-278
    • Ubuka, T.1    Kim, S.2    Huang, Y.3    Reid, J.4    Jiang, J.5    Osugi, T.6    Chowdhury, V.S.7    Tsutsui, K.8    Bentley, G.E.9
  • 176
    • 77949494829 scopus 로고    scopus 로고
    • Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic-pituitary axis
    • Ubuka T, Morgan K, Pawson AJ, Osugi T, Chowdhury VS, Minakata H, Tsutsui K, Millar RP & Bentley GE 2009b Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic-pituitary axis. PLoS ONE 4 e8400. (doi:10.1371/journal.pone.0008400)
    • (2009) PLoS ONE , vol.4 , pp. e8400
    • Ubuka, T.1    Morgan, K.2    Pawson, A.J.3    Osugi, T.4    Chowdhury, V.S.5    Minakata, H.6    Tsutsui, K.7    Millar, R.P.8    Bentley, G.E.9
  • 177
    • 84455185108 scopus 로고    scopus 로고
    • Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone
    • Ubuka T, Inoue K, Fukuda Y, Mizuno T, Ukena K, Kriegsfeld LJ & Tsutsui K 2012 Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory hormone. Endocrinology 153 373-385. (doi:10.1210/en.2011-1110)
    • (2012) Endocrinology , vol.153 , pp. 373-385
    • Ubuka, T.1    Inoue, K.2    Fukuda, Y.3    Mizuno, T.4    Ukena, K.5    Kriegsfeld, L.J.6    Tsutsui, K.7
  • 180
    • 84908613414 scopus 로고    scopus 로고
    • Endogenous kisspeptin tone is a critical excitatory component of spontaneous GnRH activity and the GnRH response to NPY and CART
    • Verma S, Kirigiti MA, Millar RP, Grove KL & Smith MS 2014 Endogenous kisspeptin tone is a critical excitatory component of spontaneous GnRH activity and the GnRH response to NPY and CART. Neuroendocrinology 99 190-203. (doi:10.1159/000365419)
    • (2014) Neuroendocrinology , vol.99 , pp. 190-203
    • Verma, S.1    Kirigiti, M.A.2    Millar, R.P.3    Grove, K.L.4    Smith, M.S.5
  • 183
    • 54949113577 scopus 로고    scopus 로고
    • Short-term fasting attenuates the response of the HPG axis to kisspeptin challenge in the adult male rhesus monkey (Macaca mulatta)
    • Wahab F, Aziz F, Irfan S, Zaman W-U & Shahab M 2008 Short-term fasting attenuates the response of the HPG axis to kisspeptin challenge in the adult male rhesus monkey (Macaca mulatta). Life Sciences 83 633-637. (doi:10.1016/j.lfs.2008.09.001)
    • (2008) Life Sciences , vol.83 , pp. 633-637
    • Wahab, F.1    Aziz, F.2    Irfan, S.3    Zaman, W.-U.4    Shahab, M.5
  • 184
    • 77954220347 scopus 로고    scopus 로고
    • Effect of peripheral kisspeptin administration on adiponectin, leptin, and resistin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta)
    • Wahab F, Bano R, Jabeen S, Irfan S & Shahab M 2010 Effect of peripheral kisspeptin administration on adiponectin, leptin, and resistin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta). Hormone and Metabolic Research 42 570-574. (doi:10.1055/s-0030-1252016)
    • (2010) Hormone and Metabolic Research , vol.42 , pp. 570-574
    • Wahab, F.1    Bano, R.2    Jabeen, S.3    Irfan, S.4    Shahab, M.5
  • 185
    • 79551610919 scopus 로고    scopus 로고
    • Decrease in hypothalamic Kiss1 and Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta)
    • Wahab F, Ullah F, Chan Y-M, Seminara SB & Shahab M 2011a Decrease in hypothalamic Kiss1 and Kiss1r expression: a potential mechanism for fasting-induced suppression of the HPG axis in the adult male rhesus monkey (Macaca mulatta). Hormone and Metabolic Research 43 81-85. (doi:10.1055/s-0030-1269852)
    • (2011) Hormone and Metabolic Research , vol.43 , pp. 81-85
    • Wahab, F.1    Ullah, F.2    Chan, Y.-M.3    Seminara, S.B.4    Shahab, M.5
  • 186
    • 80053383522 scopus 로고    scopus 로고
    • The kisspeptin signaling pathway and its role in human isolated GnRH deficiency
    • Wahab F, Quinton R & Seminara SB 2011b The kisspeptin signaling pathway and its role in human isolated GnRH deficiency. Molecular and Cellular Endocrinology 346 29-36. (doi:10.1016/j.mce.2011.05.043)
    • (2011) Molecular and Cellular Endocrinology , vol.346 , pp. 29-36
    • Wahab, F.1    Quinton, R.2    Seminara, S.B.3
  • 187
    • 78650949114 scopus 로고    scopus 로고
    • Study on the effect of peripheral kisspeptin administration on basal and glucose-induced insulin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta)
    • Wahab F, Riaz T & Shahab M 2011c Study on the effect of peripheral kisspeptin administration on basal and glucose-induced insulin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta). Hormone and Metabolic Research 43 37-42. (doi:10.1055/s-0030-1268458)
    • (2011) Hormone and Metabolic Research , vol.43 , pp. 37-42
    • Wahab, F.1    Riaz, T.2    Shahab, M.3
  • 188
    • 84861703177 scopus 로고    scopus 로고
    • Differential response of the primate HPG axis to N-methyl-D, L-aspartate, but not to Kisspeptin challenge under euglycemic and hypoglycemic conditions
    • Wahab F, Zaman W-U & Shahab M 2012 Differential response of the primate HPG axis to N-methyl-D, L-aspartate, but not to Kisspeptin challenge under euglycemic and hypoglycemic conditions. Hormone and Metabolic Research 44 451-457. (doi:10.1055/s-0032-1306309)
    • (2012) Hormone and Metabolic Research , vol.44 , pp. 451-457
    • Wahab, F.1    Zaman, W.-U.2    Shahab, M.3
  • 189
    • 84879554065 scopus 로고    scopus 로고
    • Kisspeptin as a link between metabolism and reproduction: evidences from rodent and primate studies
    • Wahab F, Atika B & Shahab M 2013a Kisspeptin as a link between metabolism and reproduction: evidences from rodent and primate studies. Metabolism: Clinical and Experimental 62 898-910. (doi:10.1016/j.metabol.2013.01.015)
    • (2013) Metabolism: Clinical and Experimental , vol.62 , pp. 898-910
    • Wahab, F.1    Atika, B.2    Shahab, M.3
  • 191
    • 84895520553 scopus 로고    scopus 로고
    • Primate HPT axis response to the peripheral kisspeptin challenge under different time periods of food restriction in monkeys
    • Wahab F, Atika B, Huma T & Shahab M 2014 Primate HPT axis response to the peripheral kisspeptin challenge under different time periods of food restriction in monkeys. Hormone and Metabolic Research 46 187-192. (doi:10.1055/s-0033-1363263)
    • (2014) Hormone and Metabolic Research , vol.46 , pp. 187-192
    • Wahab, F.1    Atika, B.2    Huma, T.3    Shahab, M.4
  • 192
    • 70350127131 scopus 로고    scopus 로고
    • Melaninconcentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction
    • Wu M, Dumalska I, Morozova E, van den Pol A & Alreja M 2009 Melaninconcentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction. PNAS 106 17217-17222. (doi:10.1073/pnas.0908200106)
    • (2009) PNAS , vol.106 , pp. 17217-17222
    • Wu, M.1    Dumalska, I.2    Morozova, E.3    van den Pol, A.4    Alreja, M.5
  • 195
    • 0037441867 scopus 로고    scopus 로고
    • Molecular properties of endogenous RFamide-related peptide-3 and its interaction with receptors
    • Yoshida H, Habata Y, Hosoya M, Kawamata Y, Kitada C & Hinuma S 2003 Molecular properties of endogenous RFamide-related peptide-3 and its interaction with receptors. Biochimica et Biophysica Acta 1593 151-157. (doi:10.1016/S0167-4889(02)00389-0)
    • (2003) Biochimica et Biophysica Acta , vol.1593 , pp. 151-157
    • Yoshida, H.1    Habata, Y.2    Hosoya, M.3    Kawamata, Y.4    Kitada, C.5    Hinuma, S.6
  • 197
    • 84887064714 scopus 로고    scopus 로고
    • Leptin signaling in GABA neurons, but not glutamate neurons, is required for reproductive function
    • Zuure WA, Roberts AL, Quennell JH & Anderson GM 2013 Leptin signaling in GABA neurons, but not glutamate neurons, is required for reproductive function. Journal of Neuroscience 33 17874-17883. (doi:10.1523/JNEUROSCI.2278-13.2013)
    • (2013) Journal of Neuroscience , vol.33 , pp. 17874-17883
    • Zuure, W.A.1    Roberts, A.L.2    Quennell, J.H.3    Anderson, G.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.