Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat

Endocrinology

Volumn 146, Issue 4, 2005, Pages 1689-1697

  Navarro, V M ^a   Castellano, J M ^a   Fernandez Fernandez R ^a   Tovar, S ^b   Roa, J ^a   Mayen, A ^a   Barreiro, M L ^a   Casanueva, F F ^b   Aguilar, E ^a   Dieguez, C ^b   Pinilla, L ^a   Tena Sempere, Manuel ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; DIZOCILPINE; EXCITATORY AMINO ACID; FOLLITROPIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 54; GONADORELIN; GONADORELIN[1 (N ACETYL 4 CHLORO DEXTRO PHENYLALANINE) 2 (4 CHLORO DEXTRO PHENYLALANINE) 3 DEXTRO TRYPTOPHAN 6 DEXTRO ARGININE 10 DEXTRO ALANINE]; GONADOTROPIN; KISSPEPTIN; LEPTIN; LIGAND; LUTEINIZING HORMONE; METASTIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; FEMALE; FOLLITROPIN RELEASE; GONADOTROPIN RELEASE; HORMONE DEFICIENCY; HYPOPHYSIS; IN VITRO STUDY; IN VIVO STUDY; MALE; NEUROENDOCRINE SYSTEM; NONHUMAN; PREPUBERTY; PRIORITY JOURNAL; RAT; REPRODUCTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ANIMALS; EXCITATORY AMINO ACIDS; FEMALE; FOLLICLE STIMULATING HORMONE; GONADOTROPIN-RELEASING HORMONE; LUTEINIZING HORMONE; MALE; NITRIC OXIDE; PROTEINS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE;

EID: 20144372084     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2004-1353     Document Type: Article

References (44)

1. Fink G 2000 Neuroendocrine regulation of pituitary function: general principles. In: Conn PM, Freeman ME, eds. Neuroendocrinology in physiology and medicine. Totowa, NJ: Humana Press; 107-134
2. Tena-Sempere M, Huhtaniemi I 2003 Gonadotropins and gonadotropin receptors. In: Fauser BCJM, ed. Reproductive medicine: molecular, cellular and genetic fundamentals. New York: Parthenon Publishing; 225-244
3. Ojeda SR, Urbanski HF 1994 Puberty in the rat. In: Knobil E, Neill JD, eds. The physiology of reproduction. New York: Raven Press; 363-410
4. Limonta P, Moretti RM, Montagnani M, Motta M 2003 The biology of gonadotropin hormone-releasing hormone: role in the control of tumor growth and progression in humans. Front Neuroendocrinol 24:279-295
5. de Roux N, Genin E, Carel JC, Matsuda F, Chaussain JL, Milgrom E 2003 Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci USA 100:10972-10976
6. Seminara SB, Messager S, Chatzidaki EE, Thresher RR, Acierno JS, Shagoury JK, Bo-Abbas Y, Kuohung W, Schwinof KM, Hendrick AG, Zahn D, Dixon J, Kaiser UB, Slaugenhaupt SA, Gusella JF, O'Rahilly S, Carlton MB, Crowley WF, Aparicio SA, Colledge WH 2003 The GPR54 gene as a regulator of puberty. New Engl J Med 349:1614-1627
7. Funes S, Hendrick JA, Vassileva G, Markowitz L, Abbondanzo S, Golovko A, Yang S, Monsma FJ, Gustafson EL 2003 The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system. Biochem Biophys Res Commun 312:1357-1363
8. Ohtaki T, Shintani Y, Honda S, Matsumoto H, Hori A, Kanehashi K, Terao Y, Kumano S, Takatsu Y, Masuda Y, Ishibashi Y, Watanabe T, Asada M, Yamada T, Suenaga M, Fujino C, Usuki S, Kurokawa T, Onda H, Nishimura O, Fujino M 2001 Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G protein-coupled receptor. Nature 411:613-617
9. Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CGC, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC 2001 AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. J Biol Chem 276:28969-28975
10. Kotani M, Detheux M, Vandenbogaerde A, Communi D, Vanderwinden JM, Le Poul E, Brezillon S, Tyldesley R, Suarez-Huerta N, Vandeput F, Blanpain C, Schiffmann SN, Vassart G, Parmentier M 2001 The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem 276:34631-34636
11. Lee DK, Nguyen T, O'Neill GP, Chang R, Liu Y, Howard AD, Coulombe N, Tan CP, Tang-Nguyen AT, George SR, O'Dowd BF 1999 Discovery of a receptor related to the galanin receptors. FEBS Lett 446:103-107
12. Lee JH, Welch DR 1997 Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1. Cancer Res 57:2384-2387
13. Ringel MD, Hardy E, Bernet VJ, Burch HB, Schuppert F, Burman KD, Saji M 2002 Metastin receptor is overexpressed in papillary thyroid cancer and activates MAP kinase in thyroid cancer cells. J Clin Endocrinol Metab 87: 2399-2402
14. Masui T, Doi R, Mori T, Toyoda E, Koizumi M, Kami K, Ito D, Peiper SC, Broach JR, Oishi S, Niida A, Fujii N, Imamura M 2004 Metastin and its variant forms suppress migration of pancreatic cancer cells. Biochem Biophys Res Commun 315:85-92
15. Bilban M, Ghaffari-Tabrizi N, Hintermann E, Bauer S, Molzer S, Zoratti C, Malli R, Sharabi A, Hiden U, Graier W, Knofler M, Andreae F, Wagner O, Quaranta V, Desoye G 2004 Kisspeptin-10, a KiSS-1/metastin-derived decapeptide, is a physiological invasion inhibitor of primary human trophoblasts. J Cell Sci 117:1319-1328
16. Horikoshi Y, Matsumoto H, Takatsu Y, Ohtaki T, Kitada C, Usuki S, Fujino M 2003 Dramatic elevation of plasma metastin concentrations in human pregnancy: metastin as a novel placental-derived hormone in humans. J Clin Endocrinol Metab 88:914-919
17. Gottsch ML, Cunningham MJ, Smith JT, Popa SM, Acohido BV, Crowley WF, Seminara S, Clifton DK, Steiner RA 2004 A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145:4073-4077
18. Matsui H, Takatsu Y, Kumano S, Matsumoto H, Ohtaki T 2004 Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun 320:383-388
19. Navarro VM, Castellano JM, Fernandez-Fernandez R, Barreiro ML, Roa J, Sanchez-Criado JE, Aguilar E, Dieguez C, Pinilla L, Tena-Sempere M 2004 Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor GPR54 in rat hypothalamus and potent LH releasing activity of KiSS-1 peptide. Endocrinology 145:4565-4574
20. Sanchez-Criado JE, Bellido C, Lopez FJ, Galiot F 1992 Antiprogesterone RU486 induces dissociation of LH and FSH secretion in the cyclic rat: effect of anti-inhibin serum. J Endocrinol 134:43-49
21. Moran C, Garcia-Hernandez E, Barahona E, Gonzalez S, Bermudez JA 2003 Relationship between insulin resistance and gonadotropin dissociation in obese and nonobese women with polycystic ovary syndrome. Fertil Steril 80:1466-1472
22. Moore Jr JP, Wilson L, Dalkin AC, Winters SJ 2003 Differential expression of the pituitary gonadotropin subunit genes during male rat sexual maturation: reciprocal relationship between hypothalamic pituitary adenylate cyclase-activating polypeptide and follicle-stimulating hormone beta expression. Biol Reprod 69:234-241
23. Yu WH, Karanth S, Walczewska, Sower SA, McCann SM 1997 A hypothalamic follicle-stimulating hormone-releasing hormone decapeptide in the rat. Proc Natl Acad Sci USA 94:9499-9503
24. Yu WH, Karanth S, Sower SA, Parlow AF, McCann SM 2002 The similarity of FSH-releasing factor to lamprey gonadotropin-releasing hormone III (GnRH-III). Proc Soc Exp Biol Med 224:87-92
25. Tena-Sempere M, Aguilar E, Fernandez-Fernandez R, Pinilla L 2004 Ghrelin inhibits prolactin secretion in prepubertal rats. Neuroendocrinology 79:133-141
26. Pinilla L, Gonzalez LC, Tena-Sempere M, Aguilar E 2000 Activation of AMPA receptors inhibits prolactin and estradiol secretion and delays the onset of puberty in female rats. J Steroid Biochem Mol Biol 75:277-281
27. Furuta M, Funabashi T, Kimura F 2001 Intracerebroventricular administration of ghrelin rapidly suppresses pulsatile luteinizing hormone secretion in ovariectomized rats. Biochem Biophys Res Commun 288:780-785
28. Gonzalez LC, Pinilla L, Tena-Sempere M, Aguilar E 1999 Regulation of growth hormone secretion by α-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptors in infantile, prepubertal, and adult male rats. Endocrinology 140:1279-1284
29. Tena-Sempere M, Pinilla L, Aguilar E 1995 Orchidectomy selectively increases follicle-stimulating hormone secretion in gonadotropin-releasing hormone antagonist-treated male rats. Eur J Endocrinol 132:357-362
30. Pinilla L, Gonzalez L, Tena Sempere M, Dieguez C, Aguilar E 1999 Gonadal and age-related influences on NMDA-induced growth hormone secretion in male rats. Neuroendocrinology 69:11-19
31. Casanueva FF, Dieguez C 1999 Neuroendocrine regulation and actions of leptin. Front Neuroendocrinol 20:317-363
32. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF 1996 Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295
33. Brann DW, Mahesh VB 1997 Excitatory amino acids: evidence for a role in the control of reproduction and anterior pituitary hormone secretion. Endocr Rev 18:678-700
34. Knauf C, Prevot V, Stefano GB, Mortreux G, Beauvillain JC, Croix D 2001 Evidence for a spontaneous nitric oxide release from the rat median eminence: influence on gonadotropin-releasing hormone release. Endocrinology 142:4288-4294
35. Carro E, Pinilla L, Seoane LM, Considine RV, Aguilar E, Casanueva FF, Dieguez C 1997 Influence of endogenous leptin tone on the estrous cycle and luteinizing hormone pulsatility in female rats. Neuroendocrinology 66:375-377
36. Navarro VM, Castellano JM, Fernandez-Fernandez R, Tovar S, Roa J, Mayen A, Nogueiras R, Vazquez MJ, Barreiro ML, Magni P, Aguilar E, Dieguez C, Pinilla L, Tena-Sempere M 2005 Characterization of the potent LH releasing activity of KiSS-1 peptide, the natural ligand of GPR54. Endocrinology 146: 156-163
37. Navarro VM, Fernandez-Fernandez R, Castellano JM, Roa J, Mayen A, Barreiro ML, Gaytan F, Aguilar E, Pinilla L, Dieguez C, Tena-Sempere M 2004 Advanced vaginal opening and precocious activation of the reproductive axis by KiSS-1 peptide, the endogenous ligand of GPR54. J Physiol 561:379-386
38. Millar RP, Lu Z-L, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR 2004 Gonadotropin-releasing hormone receptors. Endocr Rev 25:235-275
39. Wildt L, Hausler A, Marshall G, Hutchison JS, Plant TM, Belchetz PE, Knobil E 1981 Frequency and amplitude of gonadotropin-releasing hormone stimulation and gonadotropin secretion in the rhesus monkey. Endocrinology 109: 376-385
40. Burger LL, Dalkin AC, Aylor KW, Haisenleder DJ, Marshall JC 2002 GnRH pulse frequency modulation of gonadotropin subunit gene transcription in normal gonadotropes: assessment by primary transcript assay provides evidence for roles of GnRH and follistatin. Endocrinology 143:3243-3249
41. Bedecarrats GY, Kaiser UB 2003 Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused LβT2 cells: role of GnRH receptor concentration. Endocrinology 144:1802-1811
42. Thompson EL, Patterson M, Murphy KG, Smith KL, Dhillo WS, Todd JF, Ghatei MA, Bloom SR 2004 Central and peripheral administration of Kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol 16:850-858
43. Peruzzo B, Pastor FE, Blazquez JL, Schobitz K, Pelaez B, Amat P, Rodriguez EM 2000 A second look at the barriers of the mediaibasal hypothalamus. Exp Brain Res 132:10-26
44. Crowley WF, Bedside to bench research in the 21st century: the critical role of human disease models in understanding reproduction. 12th International Congress of Endocrinology, Lisbon, Portugal, 2004, p 59 (Abstract PL4)