Analysis of the expression of neurokinin B, kisspeptin, and their cognate receptors NK3R and KISS1R in the human female genital tract

Fertility and Sterility

Volumn 97, Issue 5, 2012, Pages 1213-1219

  Cejudo Roman, Antonio ^a   Pinto, Francisco M ^a   Dorta, Idaira ^b   Almeida, Teresa A ^b   Hernández, Mariano ^b   Illanes, Matilde ^c   Tena Sempere, Manuel ^d   Candenas, Luz ^a  

^a INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

^b UNIVERSIDAD DE LA LAGUNA   (Spain)

^c UNIVERSITY OF SEVILLE   (Spain)

^d UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Human female reproductive tract; KISS1 receptor; kisspeptin; neurokinin B; NK3 receptor

Indexed keywords

G PROTEIN COUPLED RECEPTOR 54; KISSPEPTIN; MESSENGER RNA; NEUROKININ 3 RECEPTOR; NEUROKININ B;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENDOMETRIUM; ENDOMETRIUM CELL; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MYOMETRIUM; OVARY; OVIDUCT; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAINING; UTERINE TUBE; UTERUS;

ENDOMETRIUM; FALLOPIAN TUBES; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; KISSPEPTINS; NEUROKININ B; OVARY; POSTMENOPAUSE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROKININ-3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEXUAL MATURATION; UTERUS;

EID: 84860344698     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2012.02.021     Document Type: Article

References (43)

1. J.N. Pennefather, A. Lecci, M.L. Candenas, E. Patak, F.M. Pinto, and C.A. Maggi Tachykinins and tachykinin receptors: a growing family Life Sci 74 2004 1445 1463 (Pubitemid 38077208)
2. H. Satake, and T. Kawada Overview of the primary structure, tissue-distribution, and functions of tachykinins and their receptors Curr Drug Targets 7 2006 963 974
3. T.A. Almeida, J. Rojo, P.M. Nieto, F.M. Pinto, M. Hernandez, J.D. Martin, and M.L. Candenas Tachykinins and tachykinin receptors: structure and activity relationships Curr Med Chem 11 2004 2045 2081 (Pubitemid 38967729)
4. M. Lasaga, and L. Debeljuk Tachykinins and the hypothalamo-pituitary- gonadal axis: an update Peptides 32 2011 1972 1978
5. A.K. Topaloglu, F. Reimann, M. Guclu, A.S. Yalin, L.D. Kotan, and K.M. Porter TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for neurokinin B in the central control of reproduction Nature Genet 41 2009 354 358
6. R.K. Semple, and A.K. Topaloglu Neurokinin B and its receptor in hypogonadotropic hypogonadism Front Horm Res 39 2010 1333 1341
7. J. Young, J. Bouligand, B. Francou, M.L. Raffin-Sanson, S. Gaillez, and M. Jeanpierre TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans J Clin Endocrinol Metab 95 2010 2287 2295
8. E. Gianetti, C. Tusset, S.D. Noel, M.G. Au, A.A. Dwyer, and V.A. Hughes TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood J Clin Endocrinol Metab 95 2010 2857 2867
9. M.N. Lehman, L.M. Coolen, and R.L. Goodman Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion Endocrinology 151 2010 3479 3489
10. N. de Roux, E. Genin, J.C. Carel, F. Matsuda, J.L. Chaussain, and E. Milgrom Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54 Proc Natl Acad Sci USA 100 2003 10972 10976 (Pubitemid 37140137)
11. S.B. Seminara, S. Messager, E.E. Chatzidaki, R.R. Thresher, J.S. Acierno Jr., and J.K. Shagoury The GPR54 gene as a regulator of puberty N Engl J Med 349 2003 1614 1627 (Pubitemid 37303886)
12. V.M. Navarro, J.M. Castellano, R. Fernandez-Fernandez, M.L. Barreiro, J. Roa, and J.E. Sanchez-Criado Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide Endocrinology 145 2004 4565 4574 (Pubitemid 39281449)
13. V.M. Navarro, and M. Tena-Sempere Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility Nature Rev Endocrinol 8 2011 40 53
14. N.E. Rance, and W.S. Young III Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women Endocrinology 128 1991 2239 2247
15. N.E. Rance Menopause and the human hypothalamus: evidence for the role of kisspeptin/neurokinin B neurons in the regulation of estrogen negative feedback Peptides 30 2009 111 122
16. R.L. Goodman, M.N. Lehman, J.T. Smith, L.M. Coolen, C.V. de Oliveira, and M.R. Jafarzadehshirazi Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B Endocrinology 148 2007 5752 5760 (Pubitemid 350146171)
17. F.M. Pinto, C.P. Armesto, J. Magraner, M. Trujillo, J.D. Martín, and M.L. Candenas Tachykinin receptor and neutral endopeptidase gene expression in the rat uterus: characterization and regulation in response to ovarian steroid treatment Endocrinology 140 1999 2526 2532 (Pubitemid 32245129)
18. N.M. Page, R.J. Woods, S.M. Gardiner, K. Lomthaisong, R.T. Gladwell, and D.J. Butlin Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia Nature 405 2000 797 800 (Pubitemid 30407852)
19. N.M. Page, J. Dakour, and D.W. Morrish Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsia Mol Hum Reprod 12 2006 427 433 (Pubitemid 44288201)
20. J.N. Pennefather, E. Patak, F.M. Pinto, and M.L. Candenas Mammalian tachykinins and uterine smooth muscle: the challenge escalates Eur J Pharmacol 500 2004 15 26 (Pubitemid 39303993)
21. C.O. Pintado, F.M. Pinto, J.N. Pennefather, A. Hidalgo, A. Baamonde, T. Sanchez, and M.L. Candenas A role for tachykinins in female mouse and rat reproductive function Biol Reprod 69 2003 940 946 (Pubitemid 37064623)
22. S. Löffler, A. Schulz, E. Brylla, K. Nieber, and K. Spanel-Borowski Transcripts of neurokinin B and neurokinin 3 receptor in superovulated rat ovaries and increased number of corpora lutea as a non-specific effect of intraperitoneal agonist application Regul Pept 122 2004 131 137 (Pubitemid 39233646)
23. F.M. Pinto, T.A. Almeida, M. Hernandez, P. Devillier, C. Advenier, and M.L. Candenas mRNA expression of tachykinins and tachykinin receptors in different human tissues Eur J Pharmacol 494 2004 233 239 (Pubitemid 38798110)
24. L. Candenas, A. Lecci, F.M. Pinto, E. Patak, C.A. Maggi, and J.N. Pennefather Tachykinins and tachykinin receptors: effects in the genitourinary tract Life Sci 76 2005 835 862 (Pubitemid 39601890)
25. C.G. Ravina, M. Seda, F.M. Pinto, A. Orea, M. Fernandez-Sanchez, C.O. Pintado, and M.L. Candenas A role for tachykinins in the regulation of human sperm motility Hum Reprod 22 2007 1617 1625 (Pubitemid 47055151)
26. G.P. Hamlin, M.J. Williams, A.J. Nimmo, and L.H. Crane Hormonal variation of rat uterine contractile responsiveness to selective neurokinin receptor agonists Biol Reprod 62 2000 1661 1666 (Pubitemid 30333749)
27. C.G. Cintado, F.M. Pinto, P. Devillier, A. Merida, and M.L. Candenas Increase in neurokinin B expression and in tachykinin NK(3) receptor-mediated response and expression in the rat uterus with age J Pharmacol Exp Ther 299 2001 934 938 (Pubitemid 33104962)
28. M.L. Candenas, J. Magraner, C.P. Armesto, E. Anselmi, P.M. Nieto, and J.D. Martín Changes in the expression of tachykinin receptors in the rat uterus during the course of pregnancy Biol Reprod 65 2001 538 543 (Pubitemid 32702319)
29. E. Patak, M.L. Candenas, J.N. Pennefather, S. Ziccone, A. Lilley, and J.D. Martin Tachykinins and tachykinin receptors in human uterus Br J Pharmacol 139 2003 523 532 (Pubitemid 36819622)
30. E. Patak, F.M. Pinto, M.E. Story, C.O. Pintado, A. Fleming, and N.M. Page Functional and molecular characterization of tachykinins and tachykinin receptors in the mouse uterus Biol Reprod 72 2005 1125 1133 (Pubitemid 40547976)
31. F.M. Pinto, C.O. Pintado, J.N. Pennefather, E. Patak, and L. Candenas Ovarian steroids regulate tachykinin and tachykinin receptor gene expression in the mouse uterus Reprod Biol Endocrinol 7 2009 77
32. J.M. Castellano, M. Gaytan, J. Roa, E. Vigo, V.M. Navarro, and C. Bellido Expression of KiSS-1 in rat ovary: putative local regulator of ovulation? Endocrinology 147 2006 4852 4862 (Pubitemid 44402192)
33. M. Gaytán, J.M. Castellano, J. Roa, J.E. Sánchez-Criado, M. Tena-Sempere, and F. Gaytán Expression of KiSS-1 in rat oviduct: possible involvement in prevention of ectopic implantation? Cell Tiss Res 329 2007 571 579 (Pubitemid 47231292)
34. F. Gaytán, M. Gaytán, J.M. Castellano, M. Romero, J. Roa, and B. Aparicio KiSS-1 in the mammalian ovary: distribution of kisspeptin in human and marmoset and alterations in KiSS-1 mRNA levels in a rat model of ovulatory dysfunction Am J Physiol Endocrinol Metab 296 2009 E520 E531
35. F.M. Pinto, A. Cejudo-Román, C.G. Ravina, M. Fernández- Sánchez, D. Martín-Lozano, and M. Illanes Characterization of the kisspeptin system in human spermatozoa Int J Androl 35 2012 63 73
36. T. Kawada, T. Sekiguchi, T. Sakai, M. Aoyama, and H. Satake Neuropeptides, hormone peptides, and their receptors in Ciona intestinalis: an update Zoolog Sci 27 2010 134 153
37. M. Aoyama, T. Kawada, M. Fujie, K. Hotta, T. Sakai, and T. Sekiguchi A novel biological role of tachykinins as an up-regulator of oocyte growth: identification of an evolutionary origin of tachykininergic functions in the ovary of the ascidian, Ciona intestinalis Endocrinology 149 2008 4346 4356
38. N.L. McGuire, and G.E. Bentley Neuropeptides in the gonads: from evolution to pharmacology Front Pharmacol 1 2010 114
39. W.H. Colledge GPR54 and kisspeptins Results Probl Cell Differ 46 2008 117 143
40. C. Mayer, and U. Boehm Female reproductive maturation in the absence of kisspeptin/GPR54 signaling Nat Neurosci 14 2011 704 710
41. S. Wray Insights into the uterus Exp Physiol 92 2007 621 631 (Pubitemid 47024941)
42. E.M. Casañ, F. Raga, F. Bonilla-Musoles, and M.L. Polan Human oviductal gonadotropin-releasing hormone: possible implications in fertilization, early embryonic development, and implantation J Clin Endocrinol Metab 5 2000 1377 1381 (Pubitemid 32289476)
43. Y. Xiao, Y. Ni, Y. Huang, J. Wu, R. Grossmann, and R. Zhao Effects of kisspeptin-10 on progesterone secretion in cultured chicken ovarian granulosa cells from preovulatory (F1-F3) follicles Peptides 32 2011 2091 2097