Short-term fasting attenuates the response of the HPG axis to kisspeptin challenge in the adult male rhesus monkey (Macaca mulatta)

Life Sciences

Volumn 83, Issue 19-20, 2008, Pages 633-637

  Wahab, Fazal ^a   Aziz, Farzana ^a   Irfan, Shahzad ^a   Zaman, Waheed uz ^a   Shahab, Muhammad ^a  

^a Faculty of Biological Sciences   (Pakistan)

Author keywords

Fasting; GnRH; GPR54; HPG axis; Kisspeptin; Monkey; Testosterone

Indexed keywords

CHORIONIC GONADOTROPIN; GLUCOSE; HEPARIN; HYDROCORTISONE; KETAMINE; KISSPEPTIN; KISSPEPTIN 10; TESTOSTERONE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; MALE; NEUROENDOCRINE SYSTEM; NONHUMAN; NUTRITIONAL STATUS; RADIOIMMUNOASSAY; RHESUS MONKEY; TESTOSTERONE BLOOD LEVEL;

ANIMALS; AREA UNDER CURVE; BLOOD GLUCOSE; CHORIONIC GONADOTROPIN; EXCITATORY AMINO ACID ANTAGONISTS; FASTING; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; KETAMINE; MACACA MULATTA; MALE; RADIOIMMUNOASSAY; TESTOSTERONE; TUMOR SUPPRESSOR PROTEINS;

MACACA MULATTA; PRIMATES;

EID: 54949113577     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.09.001     Document Type: Article

References (42)

1. Abbud R., and Smith M.S. Altered luteinizing hormone and prolactin responses to excitatory amino acids during lactation. Neuroendocrinology 58 4 (1993) 454-464
2. Aloi J.A., Bergendahl M., Iranmanesh A., and Veldhuis J.D. Pulsatile intravenous gonadotropin-releasing hormone administration averts fasting-induced hypogonadotropism and hypoandrogenemia in healthy, normal weight men. Journal of Clinical Endocrinology and Metabolism 82 5 (1997) 1543-1548
3. Badger T.M., Lynch E.A., and Fox P.H. Effects of fasting on luteinizing hormone dynamics in the male rat. The Journal of Nutrition 115 6 (1985) 788-797
4. Bergendahl M., Perheentupa A., and Huhtaniemi I. Starvation-induced suppression of pituitary-testicular function in rats is reversed by pulsatile gonadotropin-releasing hormone substitution. Biology of Reproduction 44 3 (1991) 413-419
5. Cameron J.L. Regulation of reproductive hormone secretion in primates by short-term changes in nutrition. Reviews of Reproduction 1 2 (1996) 117-126
6. Cameron J.L., and Nosbisch C. Suppression of pulsatile luteinizing hormone and testosterone secretion during short term food restriction in the adult male rhesus monkey (Macaca mulatta). Endocrinology 128 3 (1991) 1532-1540
7. Cameron J.L., Helmreich D.L., and Schreihofer D.A. Modulation of reproductive hormone secretion by nutritional intake: stress signals versus metabolic signals. Human Reproduction 8 2 (1993) 162-167
8. Castellano J.M., Navarro V.M., Fernández-Fernández R., Nogueiras R., Tovar S., Roa J., Vazquez M.J., Vigo E., Casanueva F.F., Aguilar E., Pinilla L., Dieguez C., and Tena-Sempere M. Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition. Endocrinology 146 9 (2005) 3917-3925
9. Castellano J.M., Navarro V.M., Fernandez-Fernandez R., Castellano J.M., Navarro V.M., Fernandez-Fernandez R., Roa J., Vigo E., Pineda R., Dieguez C., Aguilar E., Pinilla L., and Tena-Sempere M. Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats. Diabetes 55 9 (2006) 2602-2610
10. Dhillo W.S., Chaudhri O.B., Patterson M., Thompson E.L., Murphy K.G., Badman M.K., McGowan B.M., Amber V., Patel S., Ghatei M.A., and Bloom S.R. Kisspeptin-54 stimulates the hypothalamic-pituitary-gonadal axis in human males. The Journal of Clinical Endocrinology and Metabolism 90 12 (2005) 6609-6615
11. Dubey A.K., and Plant T.M. A suppression of gonadotropin secretion by cortisol in castrated male rhesus monkeys (Macaca mulatta) mediated by the interruption of hypothalamic gonadotropin-releasing hormone release. Biology of Reproduction 33 2 (1985) 423-431
12. Ebling F.J. The neuroendocrine timing of puberty. Reproduction 129 6 (2005) 675-683
13. Gottsch M.L., Clifton D.K., and Steiner R.A. Kisspepeptin-GPR54 signaling in the neuroendocrine reproductive axis. Molecular and Cellular Endocrinology 254-255 (2006) 91-96
14. Han S.K., Gottsch M.L., Lee K.J., Popa S.M., Smith J.T., Jakawich S.K., Clifton D.K., Steiner R.A., and Herbison A.E. Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of Puberty. The Journal of Neuroscience 25 49 (2005) 11349-11356
15. Helmreich D.L., Mattern L.G., and Cameron J.L. Lack of a role of the hypothalamic-pituitary-adrenal axis in the fasting-induced suppression of luteinizing hormone secretion in adult male rhesus monkeys (Macaca mulatta). Endocrinology 132 6 (1993) 2427-2437
16. Irfan S., Anees M., Wahab F., Zaman U., Shahab M., and Plant T.M. Evidence for a direct intratesticular action of kisspeptin in the adult rhesus monkey (Macaca mulatta). Program of the 90th Annual Meeting of the Endocrine Society, San Francisco, CA, USA, (abstract) OR52-6 (2008)
17. Kinoshita M., Moriyama R., Tsukamura H., and Maeda K.I. A rat model for the energetic regulation of gonadotropin secretion: role of the glucose-sensing mechanism in the brain. Domestic Animal Endocrinology 25 1 (2003) 109-120
18. Kotani M., Detheux M., Vandenbogaerde A., Communi D., Vanderwinden J.M., Le Poul E., Brezillon S., Tyldesley R., Suarez-Huerta N., Vandeput F., Blanpain C., Schiffmann S.W., Vassart G., and Parmentiex M. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligand of the orphan G protein coupled receptor GPR54. The Journal of Biological Chemistry 276 37 (2001) 34631-34536
19. Kuderling I., Dorsch G., Warnhoff M., and Pirke K.M. The actions of prostaglandin E2, naloxone and testosterone on starvation-induced suppression of luteinizing hormone-releasing hormone and luteinizing-hormone secretion. In vitro and in vivo studies. Neuroendocrinology 39 6 (1984) 530-537
20. Lado-Abeal J., Hickox J.R., Cheung T.L., Veldhuis J.D., Hardy D.M., and Norman R.L. Neuroendocrine consequences of fasting in adult male macaques: effects of recombinant rhesus macaque leptin infusion. Neuroendocrinology 71 3 (2000) 196-208
21. Lado-Abeal J., Veldhuis J.D., and Norman R.L. Glucose relays information regarding nutritional status to the neural circuits that control the somatotropic, corticotropic, and gonadotropic axes in adult male rhesus macaques. Endocrinology 143 2 (2002) 403-410
22. Lado-Abeal J., Robert-McComb J.J., Qian X.-P., Leproll R., Cauter E.V., and Norman R.L. Sex differences in the neuroendocrine response to Short-term fasting in rhesus macaques. Journal of Neuroendocrinology 17 7 (2005) 435-444
23. Luque R.M., Kineman R.D., and Tena-Sempere M. Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: Analyses using mouse models and a cell line. Endocrinology 148 10 (2007) 4601-4611
24. Matsuzaki T., Iwasa T., Minakuchi M., and Irahara M. Decreased expression of kisspeptin mediates acute immune/inflammatory stress induced suppression of gonadotropin secretion in female rat. Program of the 90th Annual Meeting of the Endocrine Society, San Francisco, CA, USA, (abstract) P2-669 (2008)
25. Muir A.I., Chamberlain L., Elshourbagy N.A., Michalovich D., Moore D.J., Calamari A., Szekers P.G., Sarav H.M., Chambers J.K., Murdock P., Steplewski K., Shabon U., Miller J.E., Middleton S.E., Darker J.G., Larminie C.G., Wilson S., Bergsma D.J., Einson P., Faull R., Philpott K.L., and Hanison D.C. AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1. The Journal of Biological Chemistry 276 31 (2001) 28969-28975
26. Patterson M., Murphy K.G., Thompson E.L., Patel S., Ghatei M.A., and Bloom S.R. Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats. Journal of Neuroendocrinology 18 5 (2006) 349-354
27. Plant T.M. The role of KiSS-1 in the regulation of puberty in higher primates. European Journal of Endocrinology 155 1 (2006) S11-16
28. Plant T.M., and Barker-Gibb M.L. Neurobiological mechanisms of puberty in higher primates. Human Reproduction Update 10 1 (2004) 67-77
29. Plant T.M., and Shahab M. Neuroendocrine mechanisms that delay and initiate puberty in higher primates. Physiology and Behavior 77 4-5 (2002) 717-722
30. Plant T.M., Ramaswamy S., and Dipietro M. Repetitive activation of hypothalamic G protein-coupled receptor 54 with intravenous pulses of kisspeptin in the juvenile monkey (Macaca mulatta) elicits a sustained train of gonadotropin-releasing hormone discharges. Endocrinology 147 2 (2006) 1007-1013
31. Ramaswamy S., Seminara S.B., Pohl C.R., DiPietro M.J., Crowley W.F., and Plant T.M. Effect of continuous intravenous administration of human metastin 45-54 on the neuroendocrine activity of the hypothalamic-pituitary-testicular axis in the adult male rhesus monkey (Macaca mulatta). Endocrinology 148 7 (2007) 3364-3370
32. Schneider J.E. Energy balance and reproduction. Physiology and Behavior 81 2 (2004) 289-317
33. Shahab M., Zaman W., Bashir K., and Arslan M. Fasting-induced suppression of hypothalamic-pituitary-gonadal axis in the adult rhesus monkey: evidence for involvement of excitatory amino acid neurotransmitters. Life Sciences 61 13 (1997) 1293-1300
34. Shahab M., Mastronardi C., Seminara S.B., Crowley W.F., Ojeda S.R., and Plant T.M. Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates. Proceedings of the National Academy of Sciences United States of America 102 6 (2005) 2129-2134
35. Shibata M., Gibbs R.B., Shahab M., and Plant T.M. GnRH neurons in the peripubertal male rhesus monkey (Macaca mulatta) express GPR54: Implication for the control of primate puberty. Program of the 87th Annual Meeting of the Endocrine Society, San Diego, CA, USA, (abstract) P1-98 (2005)
36. Smith J.T., Acohido B.V., Clifton D.K., and Steiner R.A. KiSS-1 neurones are direct targets for leptin in the ob/ob mouse. Journal of Neuroendocrinology 18 (2006) 298-303
37. Tena-Sempere M. GPR54 and kisspeptin in reproduction. Human Reproduction Update 12 5 (2006) 631-639
38. Terasawa E., and Fernandez D.L. Neurobiological mechanisms of the onset of puberty in primates. Endocrine Reviews 22 1 (2001) 111-151
39. Wade G.N., and Jones J.E. Neuroendocrinology of nutritional infertility. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 287 6 (2004) R1277-R1296
40. Wade G.N., Schneider J.E., and Li H.Y. Control of fertility by metabolic cues. American Journal of Physiology-Endocrinology and Metabolism 270 1 (1996) E1-E19
41. Wang O., JL Basko J.L., and Majzoub J.A. Stress inhibits Kiss1 mRNA expression in the arcuate nucleus of male mice. Program of the 90th Annual of the Endocrine Society, San Francisco, CA, USA, (abstract) OR17-3 (2008)
42. Yamada S., Uenoyama Y., Kinoshita M., Iwata K., Takase K., Matsui H., Adachi S., Inoue K., Maeda K.I., and Tsukamura H. Inhibition of metastin (kisspeptin-54)-GPR54 signaling in the arcuate nucleus-median eminence region during lactation in rats. Endocrinology 148 5 (2007) 2226-2232