Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons

Journal of Clinical Investigation

Volumn 121, Issue 1, 2011, Pages 355-368

  Donato Jr , Jose ^a,b   Cravo, Roberta M ^a   Frazão, Renata ^a   Gautron, Laurent ^a   Scott, Michael M ^a   Lachey, Jennifer ^c   Castro, Inar A ^b   Margatho, Lisandra O ^a   Lee, Syann ^a   Lee, Charlotte ^a   Richardson, James A ^a   Friedman, Jeffrey ^d   Chua Jr , Streamson ^e   Coppari, Roberto ^a   Zigman, Jeffrey M ^a,f   Elmquist, Joel K ^a,f   Elias, Carol F ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Acceleron Pharma   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GONADORELIN; LEPTIN; LEPTIN RECEPTOR; METASTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; FERTILITY; GENE DELETION; HYPOTHALAMUS NUCLEUS; MALE; MAMMILLARY BODY; METABOLISM; MOUSE; NERVE CELL; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBERTY; REPRODUCTION; SEXUAL MATURATION; SIGNAL TRANSDUCTION; VENTRAL PREMAMMILLARY NUCLEUS;

ANIMALS; BASE SEQUENCE; FEMALE; FERTILITY; GENE EXPRESSION; HUMANS; HYPOTHALAMUS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MICE, TRANSGENIC; NEURONS; PREGNANCY; PROTEINS; RECEPTORS, LEPTIN; RNA, MESSENGER; SEXUAL MATURATION; SIGNAL TRANSDUCTION;

EID: 78650956096     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI45106     Document Type: Article

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