Long term malnutrition and mRNAs expression of RFRP-3 and KiSS-1 in hypothalamus of female ovariectomized rats

Physiology and Pharmacology

Volumn 17, Issue 4, 2014, Pages 370-378

  Jahanara, Maliheh ^a   Tamadon, Amin ^b   Shirazi, Mohammad Reza Jafarzadeh ^a   Rahmanifar, Farhad ^c   Sarvestani, Fatemeh Sabet ^a   Tanideh, Nader ^d   Moghadam, Ali ^a   Niazi, Ali ^a  

^a SHIRAZ UNIVERSITY   (Iran)

^b SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Hypothalamus; KiSS 1 mRNA; Malnutrition; Rat; RFRP 3 mRNA

Indexed keywords

ARGININE PHENYLALANINE AMIDE RELATED PEPTIDE 3; METASTIN; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARCUATE NUCLEUS; ARTICLE; CONTROLLED STUDY; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; FEMALE; GENE EXPRESSION; HYPOTHALAMUS; MALNUTRITION; NONHUMAN; RAT; REAL TIME POLYMERASE CHAIN REACTION;

EID: 84908376625     PISSN: 17350581     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Adam CL, Archer ZA, Findlay PA, Thomas L, Marie M, Hypothalamic gene expression in sheep for cocaine-and amphetamine-regulated transcript, proopiomelanocortin, neuropeptide Y, agouti-related peptide and leptin receptor and responses to negative energy balance. Neuroendocrinology 75 (2002) 250-256.
2. Booth PJ, Cosgrove JR, Foxcroft GR, Endocrine and metabolic responses to realimentation in feed-restricted prepubertal gilts: associations among gonadotropins, metabolic hormones, glucose, and uteroovarian development. J Anim Sci 74 (1996) 840-848.
3. Brito LFC, Barth AD, Rawlings NC, Wilde RE, Crews DH, Boisclair YR, Ehrhardt RA, Kastelic JP, Effect of feed restriction during calfhood on serum concentrations of metabolic hormones, gonadotropins, testosterone, and on sexual development in bulls. Reproduction 134 (2007) 171-181.
4. Brito LFC, Barth AD, Rawlings NC, Wilde RE, Crews Jr DH, Mir PS, Kastelic JP, Effect of nutrition during calfhood and peripubertal period on serum metabolic hormones, gonadotropins and testosterone concentrations, and on sexual development in bulls. Domest Anim Endocrinol 33 (2007) 1-18.
5. Calisi RM, Rizzo NO, Bentley GE, Seasonal differences in hypothalamic EGR-1 and GnIH expression following capture-handling stress in house sparrows (Passer domesticus). Gen Comp Endocrinol 157 (2008) 283-287.
6. Castellano JM, Navarro VM, Fernandez-Fernandez R, Nogueiras R, Tovar S, Roa J, Vazquez MJ, Vigo E, Casanueva FF, Aguilar E, Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition. Endocrinology 146 (2005) 3917-3925.
7. Castellano JM, Roa J, Luque RM, Dieguez C, Aguilar E, Pinilla L, Tena-Sempere M, KiSS-1/kisspeptins and the metabolic control of reproduction: physiologic roles and putative physiopathological implications. Peptides 30 (2009) 139-145.
8. Chowdhury VS, Tomonaga S, Nishimura S, Tabata S, Cockrem JF, Tsutsui K, Furuse M, Hypothalamic gonadotropin-inhibitory hormone precursor mRNA is increased during depressed food intake in heat-exposed chicks. Comp Biochem Physiol A Mol Integr Physiol 162 (2012) 227-233.
9. Clarke IJ, Qi Y, Puspita Sari I, Smith JT, Evidence that RF-amide related peptides are inhibitors of reproduction in mammals. Front Neuroendocrinol 30 (2009) 371-378.
10. Clarke IJ, Smith JT, Henry BA, Oldfield BJ, Stefanidis A, Millar RP, Sari IP, Chng K, Fabre-Nys C, Caraty A, Gonadotropin-inhibitory hormone is a hypothalamic peptide that provides a molecular switch between reproduction and feeding. Neuroendocrinology 95 (2012) 305-316.
11. Dhillo W, Murphy K, Bloom S, The neuroendocrine physiology of kisspeptin in the human. Rev Endocr Metab Disord 8 (2007) 41-46.
12. Dorling AA, Todman MG, Korach KS, Herbison AE, Critical role for estrogen receptor alpha in negative feedback regulation of gonadotropin-releasing hormone mRNA expression in the female mouse. Neuroendocrinology 78 (2003) 204-209.
13. Fernandez-Fernandez R, Martini AC, Navarro VM, Castellano JM, Dieguez C, Aguilar E, Pinilla L, Tena-Sempere M, Novel signals for the integration of energy balance and reproduction. Mol Cell Endocrinol 254 (2006) 127-132.
14. Fraley GS, Coombs E, Gerometta E, Colton S, Sharp PJ, Li Q, Clarke IJ, Distribution and sequence of Gonadotropin-inhibitory hormone and its potential role as a molecular link between feeding and reproductive systems in the Pekin duck (Anas platyrhynchos domestica). Gen Comp Endocrinol 184 (2013) 103-110.
15. Gottsch ML, Cunningham MJ, Smith JT, Popa SM, Acohido BV, Crowley WF, Seminara S, Clifton DK, Steiner RA, A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145 (2004) 4073-4077.
16. Hill JW, Elmquist JK, Elias CF, Hypothalamic pathways linking energy balance and reproduction. Am J Physiol Endocrinol Metab 294 (2008) E827-E832.
17. Iwasa T, Matsuzaki T, Murakami M, Kinouchi R, Gereltsetseg G, Fujisawa S, Kuwahara A, Yasui T, Irahara M, Sensitivities of mRNA expression levels of Kiss1 and its receptor, Kiss1r, to nutritional status are changed during the developmental period in female rats. J Endocrinol 207 (2010) 195-202.
18. Johnson MA, Tsutsui K, Fraley GS, Rat RFamiderelated peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat. Horm Behav 51 (2007) 171-180.
19. Kirby ED, Geraghty AC, Ubuka T, Bentley GE, Kaufer D, Stress increases putative gonadotropin inhibitory hormone and decreases luteinizing hormone in male rats. Proc Natl Acad Sci 106 (2009) 11324-11329.
20. Klingerman CM, Williams Iii WP, Simberlund J, Brahme N, Prasad A, Schneider JE, Kriegsfeld LJ, Food restriction-induced changes in gonadotropin-inhibiting hormone cells are associated with changes in sexual motivation and food hoarding, but not sexual performance and food intake. Front Endocrinol 2 (2011) 1-15.
21. Kriegsfeld LJ, Mei DF, Bentley GE, Ubuka T, Mason AO, Inoue K, Ukena K, Tsutsui K, Silver R, Identification and characterization of a gonadotropininhibitory system in the brains of mammals. Proc Natl Acad Sci U S A 103 (2006) 2410-2415.
22. Kumar S, Kaur G, Intermittent fasting dietary restriction regimen negatively influences reproduction in young rats: a study of hypothalamo-hypophysial-gonadal axis. PLoS ONE 8 (2013) 1-15.
23. Luque RM, Kineman RD, Tena-Sempere M, Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line. Endocrinology 148 (2007) 4601-4611.
24. Matsui H, Takatsu Y, Kumano S, Matsumoto H, Ohtaki T, Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun 320 (2004) 383-388.
25. Paxinos G, Watson C, editors. The Rat Brain in Stereotaxic Coordinates. 6th ed. New York: Academic Press, 2007.
26. Pillon D, Caraty A, Fabre-Nys C, Bruneau G, Shortterm effect of oestradiol on neurokinin B mRNA expression in the infundibular nucleus of ewes. J Neuroendocrinol 15 (2003) 749-753.
27. Qi Y, Oldfield BJ, Clarke IJ, Projections of RFamiderelated peptide-3 neurones in the ovine hypothalamus, with special reference to regions regulating energy balance and reproduction. J Neuroendocrinol 21 (2009) 690-697.
28. Quesnel H, Pasquier A, Mounier AM, Prunier A, Influence of feed restriction during lactation on gonadotropic hormones and ovarian development in primiparous sows. J Anim Sci 76 (1998) 856-863.
29. Salehi MS, Namavar MR, Jafarzadeh Shirazi MR, Rahmanifar F, Tamadon A, A simple method for isolation of the anteroventral periventricular and arcuate nuclei in the rat hypothalamus. (2013) Anatomy in press.
30. Smith JT, Acohido BV, Clifton DK, Steiner RA, KiSS-1 neurones are direct targets for leptin in the ob/ob mouse. J Neuroendocrinol 18 (2006) 298-303.
31. Smith JT, Clarke IJ, Gonadotropin inhibitory hormone function in mammals. Trends Endocrinol Metab 21 (2010) 255-260.
32. Smith JT, Coolen LM, Kriegsfeld LJ, Sari IP, Jaafarzadehshirazi MR, Maltby M, Bateman K, Goodman RL, Tilbrook AJ, Ubuka T, Bentley GE, Clarke IJ, Lehman MN, Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep. Endocrinology 149 (2008) 5770-5782.
33. Smith JT, Cunningham MJ, Rissman EF, Clifton DK, Steiner RA, Regulation of Kiss1 gene expression in the brain of the female mouse. Endocrinology 146 (2005) 3686.
34. Smith JT, Rao A, Pereira A, Caraty A, Millar RP, Clarke IJ, Kisspeptin is present in ovine hypophysial portal blood but does not increase during the preovulatory luteinizing hormone surge: evidence that gonadotropes are not direct targets of kisspeptin in vivo. Endocrinology 149 (2008) 1951-1959.
35. Stutz AM, Morrison CD, Argyropoulos G, The Agoutirelated protein and its role in energy homeostasis. Peptides 26 (2005) 1771-1781.
36. Tachibana T, Sato M, Takahashi H, Ukena K, Tsutsui K, Furuse M, Gonadotropin-inhibiting hormone stimulates feeding behavior in chicks. Brain Res 1050 (2005) 94-100.
37. Tropp J, Markus EJ, Effects of mild food deprivation on the estrous cycle of rats. Physiol Behav 73 (2001) 553-559.
38. True C, Kirigiti MA, Kievit P, Grove KL, Smith MS, Leptin is not the critical signal for kisspeptin or luteinising hormone restoration during exit from negative energy balance. J Neuroendocrinol 23 (2011) 1099-1112.
39. Tsutsui K, Saigoh E, Ukena K, Teranishi H, Fujisawa Y, Kikuchi M, Ishii S, Sharp PJ, A novel avian hypothalamic peptide inhibiting gonadotropin release. Biochem Biophys Res Commun 275 (2000) 661-667.
40. Veldhuis JD, Iranmanesh A, Evans WS, Lizarralde G, Thorner MO, Vance ML, Amplitude suppression of the pulsatile mode of immunoradiometric luteinizing hormone release in fasting-induced hypoandrogenemia in normal men. J Clin Endocrinol Metab 76 (1993) 587-593.
41. Wade GN, Jones JE, Neuroendocrinology of nutritional infertility. Am J Physiol Regul Integr Comp Physiol 287 (2004) R1277-R1296.
42. Wahab F, Bano R, Jabeen S, Irfan S, Shahab M, Effect of peripheral kisspeptin administration on adiponectin, leptin, and resistin secretion under fed and fasting conditions in the adult male rhesus monkey (Macaca mulatta). Horm Metab Res 42 (2010) 570-574.
43. Wahab F, Riaz T, Shahab M, Study on the effect of peripheral kisspeptin administration on basal and glucose-induced insulin secretion under fed and fasting conditions in the adult male Rhesus monkey (Macaca mulatta). Horm Metab Res 43 (2010) 37-42.
44. Widmaier EP, Raff H, Strang KT, editors. Vander's human physiology. 11th ed.: McGraw-Hill Higher Education, 2006.