Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes

PLoS Genetics

Volumn 11, Issue 5, 2015, Pages

  Lada, Artem G ^a   Kliver, Sergei F ^b   Dhar, Alok ^c   Polev, Dmitrii E ^b   Masharsky, Alexey E ^b   Rogozin, Igor B ^d,e,f   Pavlov, Youri I ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^f NOVOSIBIRSK STATE UNIVERSITY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CYTOSINE DEAMINASE; DNA BINDING PROTEIN; PROTEIN PMCDA1; PROTEIN SUB1; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; ASPARTATE CARBAMOYLTRANSFERASE; CAN1 PROTEIN, S CEREVISIAE; CARBAMOYL PHOSPHATE SYNTHASE (GLUTAMINE HYDROLYSING); CATION TRANSPORT PROTEIN; CYTIDINE DEAMINASE; SACCHAROMYCES CEREVISIAE PROTEIN; SUB1 PROTEIN, S CEREVISIAE; TRANSCRIPTION FACTOR; TRK1 PROTEIN, S CEREVISIAE; URA2 PROTEIN, S CEREVISIAE;

ARTICLE; CAN1 GENE; CELL CULTURE; FUNGAL GENE; GENE; GENE CLUSTER; GENE DISRUPTION; GENE LOCATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; MOLECULAR CLONING; NONHUMAN; PETROMYZON; PROTEIN DEPLETION; REGULATORY MECHANISM; SUB1 GENE; TRANSCRIPTION INITIATION; YEAST; YEAST CELL; ALLELE; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDY; GENETICS; HIGH THROUGHPUT SEQUENCING; METABOLISM; MUTATION; MUTATION RATE; PROMOTER REGION; REPORTER GENE; SACCHAROMYCES CEREVISIAE; SINGLE NUCLEOTIDE POLYMORPHISM;

PETROMYZON MARINUS;

ALLELES; AMINO ACID TRANSPORT SYSTEMS, BASIC; APOBEC-1 DEAMINASE; ASPARTATE CARBAMOYLTRANSFERASE; CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING); CATION TRANSPORT PROTEINS; CYTIDINE DEAMINASE; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, REPORTER; GENETIC ASSOCIATION STUDIES; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; MUTATION; MUTATION RATE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION;

EID: 84930795728     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005217     Document Type: Article

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