Epigenetic targeting of activation-induced cytidine deaminase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 52, 2014, Pages 18667-18672

  Wang, Qiao ^a   Oliveira, Thiago ^a   Jankovic, Mila ^a   Silva, Israel T ^a   Hakim, Ofir ^b,c   Yao, Kaihui ^a   Gazumyan, Anna ^a   Mayer, Christian T ^a   Pavri, Rushad ^a,d   Casellas, Rafael ^b   Nussenzweig, Michel C ^a   Robbiani, Davide F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^c BAR ILAN UNIVERSITY   (Israel)

^d RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Active enhancer; Chromosome translocation; Lymphoma; Mouse embryonic fibroblast; Transcription elongation

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CASPASE 9; RNA POLYMERASE II; URACIL DNA GLYCOSIDASE; AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; HISTONE; IMMUNOGLOBULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELLS BY BODY ANATOMY; CHROMOSOME REARRANGEMENT; CLINICAL EVALUATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DAMAGE; DNA SEQUENCE; EMBRYO; ENHANCER REGION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME MODIFICATION; EPIGENETICS; FIBROBLAST; GENE TARGETING; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSCRIPTION ELONGATION; ANIMAL; ANIMAL EMBRYO; BIOSYNTHESIS; CELL LINE; CYTOLOGY; ENZYMOLOGY; GENETIC EPIGENESIS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; B-LYMPHOCYTES; CELL LINE; CYTIDINE DEAMINASE; EMBRYO, MAMMALIAN; EPIGENESIS, GENETIC; FIBROBLASTS; GENE TARGETING; HISTONES; IMMUNOGLOBULINS; MICE; MICE, KNOCKOUT; TRANSCRIPTION, GENETIC;

EID: 84924352927     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420575111     Document Type: Article

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