Chatting with the neighbors: Crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders

Frontiers in Neuroscience

Volumn 9, Issue MAY, 2015, Pages

  Hensel, Niko ^a,c   Rademacher, Sebastian ^a,b   Claus, Peter ^a,b,c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

^c Niedersachsen Research Network on Neuroinfectiology (N RENNT)   (Germany)

Author keywords

Actomyosin; Akt; Alzheimer disease; Amyotrophic lateral sclerosis (ALS); ERK signaling; Fasudil; Huntingtin; Huntington disease; Kinase inhibitor; Microglia; Multiple sclerosis; Neuroinflammation; Parkinson disease; Profilin; PTEN regulation; SMN; Spinal muscular atrophy

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PRESENILIN 1; PRESENILIN 2; PROTEIN KINASE B; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STAT3 PROTEIN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; CELL ACTIVATION; CELL SURVIVAL; DEGENERATIVE DISEASE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUNTINGTON CHOREA; MICROGLIA; MULTIPLE SCLEROSIS; NEUROPATHOLOGY; NONHUMAN; PARKINSON DISEASE; PROTEIN EXPRESSION; PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; SPINAL MUSCULAR ATROPHY; UPREGULATION;

EID: 84930651058     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2015.00198     Document Type: Review

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