The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin

Human Molecular Genetics

Volumn 20, Issue 24, 2011, Pages 4865-4878

  Nölle, Anna ^a,b   Zeug, Andre ^a   Van bergeijk, Jeroen ^a   Tönges, Lars ^c   Gerhard, Ralf ^a   Brinkmann, Hella ^a   Al rayes, Sarah ^a   Hensel, Niko ^a,b   Schill, Yvonne ^a   Apkhazava, David ^a   Jablonka, Sibylle ^d   O'mer, Jana ^a   Kumar srivastav, Ratnesh ^a   Baasner, Anne ^e   Lingor, Paul ^c   Wirth, Brunhilde ^e   Ponimaskin, Evgeni ^a,b   Niedenthal, Rainer ^a   Grothe, Claudia ^a,b   Claus, Peter ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; COFILIN; MYOSIN LIGHT CHAIN PHOSPHATASE; PROFILIN; PROFILIN 2A; RHO KINASE; SURVIVAL MOTOR NEURON PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CYTOSKELETON; HUMAN; HUMAN CELL; IN VIVO STUDY; MISSENSE MUTATION; MOTONEURON; MOUSE; NEURITE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SPINAL MUSCULAR ATROPHY; SUMOYLATION;

ACTIN CYTOSKELETON; ACTINS; ANIMALS; DISEASE MODELS, ANIMAL; GENE KNOCKDOWN TECHNIQUES; GROWTH CONES; HUMANS; MICE; MODELS, BIOLOGICAL; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; MUTANT PROTEINS; MUTATION, MISSENSE; NEURITES; PHOSPHORYLATION; PROFILINS; PROTEIN BINDING; RATS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SURVIVAL OF MOTOR NEURON 1 PROTEIN;

EID: 81855166084     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr425     Document Type: Article

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