Shift from extracellular signal-regulated kinase to AKT/ cAMP response element-binding protein pathway increases survival-motor-neuron expression in spinal-muscular- atrophy-like mice and patient cells

Journal of Neuroscience

Volumn 33, Issue 10, 2013, Pages 4280-4294

  Branchu, Julien ^a   Biondi, Olivier ^a   Chali, Farah ^a   Collin, Thibault ^a   Leroy, Felix ^a   Mamchaoui, Kamel ^b   Makoukji, Joelle ^a   Pariset, Claude ^a   Lopes, Philippe ^a,c   Massaad, Charbel ^a   Chanoine, Christophe ^a   Charbonnier, Frédéric ^a  

^a CNRS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ D EVRY VAL D ESSONNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SELUMETINIB; SURVIVAL MOTOR NEURON PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MYOTUBE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPINAL MUSCULAR ATROPHY; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BUTADIENES; CALCIUM; CELL SURVIVAL; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; COCULTURE TECHNIQUES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; EXPLORATORY BEHAVIOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GANGLIA, SPINAL; HUMANS; MALE; MICE; MICE, KNOCKOUT; MOTOR NEURONS; MUSCLE CELLS; MUSCULAR ATROPHY, SPINAL; N-METHYLASPARTATE; NITRILES; SIGNAL TRANSDUCTION; STEM CELLS; SURVIVAL OF MOTOR NEURON 2 PROTEIN;

EID: 84874802390     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2728-12.2013     Document Type: Article

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