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Volumn 40, Issue 4, 2003, Pages 685-694

A rapid cellular FRET assay of polyglutamine aggregation identifies a novel inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; POLYGLUTAMINE; PROTEIN P160; RHO KINASE;

EID: 0242657586     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(03)00697-4     Document Type: Article
Times cited : (137)

References (40)
  • 1
    • 0035862754 scopus 로고    scopus 로고
    • Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice
    • Abel A., Walcott J., Woods J., Duda J., Merry D. Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice. Hum. Mol. Genet. 10:2001;107-116.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 107-116
    • Abel, A.1    Walcott, J.2    Woods, J.3    Duda, J.4    Merry, D.5
  • 2
    • 0035881211 scopus 로고    scopus 로고
    • A microtiter plate assay for polyglutamine aggregate extension
    • Berthelier V., Hamilton J.B., Chen S., Wetzel R. A microtiter plate assay for polyglutamine aggregate extension. Anal. Biochem. 295:2001;227-236.
    • (2001) Anal. Biochem. , vol.295 , pp. 227-236
    • Berthelier, V.1    Hamilton, J.B.2    Chen, S.3    Wetzel, R.4
  • 4
    • 0038039288 scopus 로고    scopus 로고
    • Polyglutamine protein aggregation and toxicity are linked to the cellular stress response
    • Cowan K.J., Diamond M.I., Welch W.J. Polyglutamine protein aggregation and toxicity are linked to the cellular stress response. Hum. Mol. Genet. 12:2003;1377-1391.
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 1377-1391
    • Cowan, K.J.1    Diamond, M.I.2    Welch, W.J.3
  • 5
    • 0034681144 scopus 로고    scopus 로고
    • Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor
    • Diamond M.I., Robinson M.R., Yamamoto K.R. Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA. 97:2000;657-661.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 657-661
    • Diamond, M.I.1    Robinson, M.R.2    Yamamoto, K.R.3
  • 6
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DiFiglia M., Sapp E., Chase K.O., Davies S.W., Bates G.P., Vonsattel J.P., Aronin N. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science. 277:1997;1990-1993.
    • (1997) Science , vol.277 , pp. 1990-1993
    • Difiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 9
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville S., Hall A. Rho GTPases in cell biology. Nature. 420:2002;629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 10
    • 0344466781 scopus 로고    scopus 로고
    • Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera
    • Garcia-Mata R., Bebok Z., Sorscher E.J., Sztul E.S. Characterization and dynamics of aggresome formation by a cytosolic GFP-chimera. J. Cell Biol. 146:1999;1239-1254.
    • (1999) J. Cell Biol. , vol.146 , pp. 1239-1254
    • Garcia-Mata, R.1    Bebok, Z.2    Sorscher, E.J.3    Sztul, E.S.4
  • 15
    • 0000723251 scopus 로고
    • A novel (The Huntington's Disease Collaborative Research Group) gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington Collaborative A novel (The Huntington's Disease Collaborative Research Group) gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 72:1993;971-983.
    • (1993) Cell , vol.72 , pp. 971-983
    • Huntington Collaborative1
  • 16
    • 0030615004 scopus 로고    scopus 로고
    • P160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions
    • Ishizaki T., Naito M., Fujisawa K., Maekawa M., Watanabe N., Saito Y., Narumiya S. p160ROCK, a Rho-associated coiled-coil forming protein kinase, works downstream of Rho and induces focal adhesions. FEBS Lett. 404:1997;118-124.
    • (1997) FEBS Lett. , vol.404 , pp. 118-124
    • Ishizaki, T.1    Naito, M.2    Fujisawa, K.3    Maekawa, M.4    Watanabe, N.5    Saito, Y.6    Narumiya, S.7
  • 18
    • 0032576605 scopus 로고    scopus 로고
    • Aggresomes: A cellular response to misfolded proteins
    • Johnston J.A., Ward C.L., Kopito R.R. Aggresomes. a cellular response to misfolded proteins J. Cell Biol. 143:1998;1883-1898.
    • (1998) J. Cell Biol. , vol.143 , pp. 1883-1898
    • Johnston, J.A.1    Ward, C.L.2    Kopito, R.R.3
  • 19
    • 0014310582 scopus 로고
    • Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait
    • Kennedy W.R., Alter M., Sung J.H. Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait. Neurology. 18:1968;671-680.
    • (1968) Neurology , vol.18 , pp. 671-680
    • Kennedy, W.R.1    Alter, M.2    Sung, J.H.3
  • 21
    • 0030298138 scopus 로고    scopus 로고
    • Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade
    • Lamarche N., Tapon N., Stowers L., Burbelo P.D., Aspenstrom P., Bridges T., Chant J., Hall A. Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade. Cell. 87:1996;519-529.
    • (1996) Cell , vol.87 , pp. 519-529
    • Lamarche, N.1    Tapon, N.2    Stowers, L.3    Burbelo, P.D.4    Aspenstrom, P.5    Bridges, T.6    Chant, J.7    Hall, A.8
  • 22
    • 0025800526 scopus 로고
    • Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
    • La Spada A.R., Wilson E.M., Lubahn D.B., Harding A.E., Fischbeck K.H. Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature. 352:1991;77-79.
    • (1991) Nature , vol.352 , pp. 77-79
    • La Spada, A.R.1    Wilson, E.M.2    Lubahn, D.B.3    Harding, A.E.4    Fischbeck, K.H.5
  • 24
    • 0035858883 scopus 로고    scopus 로고
    • Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1
    • Meriin A.B., Mabuchi K., Gabai V.L., Yaglom J.A., Kazantsev A., Sherman M.Y. Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1. J. Cell Biol. 153:2001;851-864.
    • (2001) J. Cell Biol. , vol.153 , pp. 851-864
    • Meriin, A.B.1    Mabuchi, K.2    Gabai, V.L.3    Yaglom, J.A.4    Kazantsev, A.5    Sherman, M.Y.6
  • 25
    • 0031948607 scopus 로고    scopus 로고
    • Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy
    • Merry D.E., Kobayashi Y., Bailey C.K., Taye A.A., Fischbeck K.H. Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy. Hum. Mol. Genet. 7:1998;693-701.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 693-701
    • Merry, D.E.1    Kobayashi, Y.2    Bailey, C.K.3    Taye, A.A.4    Fischbeck, K.H.5
  • 26
    • 0037154229 scopus 로고    scopus 로고
    • Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment
    • Muchowski P.J., Ning K., D'Souza-Schorey C., Fields S. Requirement of an intact microtubule cytoskeleton for aggregation and inclusion body formation by a mutant huntingtin fragment. Proc. Natl. Acad. Sci. USA. 99:2002;727-732.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 727-732
    • Muchowski, P.J.1    Ning, K.2    D'souza-Schorey, C.3    Fields, S.4
  • 27
    • 0033772834 scopus 로고    scopus 로고
    • Use and properties of ROCK-specific inhibitor Y-27632
    • Narumiya S., Ishizaki T., Uehata M. Use and properties of ROCK-specific inhibitor Y-27632. Methods Enzymol. 325:2000;273-284.
    • (2000) Methods Enzymol. , vol.325 , pp. 273-284
    • Narumiya, S.1    Ishizaki, T.2    Uehata, M.3
  • 30
    • 0141521869 scopus 로고    scopus 로고
    • Biological mechanism profiling using an annotated compound library
    • Root D.E., Flaherty S.P., Kelley B.P., Stockwell B.R. Biological mechanism profiling using an annotated compound library. Chem. Biol. 10:2003;881-892.
    • (2003) Chem. Biol. , vol.10 , pp. 881-892
    • Root, D.E.1    Flaherty, S.P.2    Kelley, B.P.3    Stockwell, B.R.4
  • 31
    • 0037855765 scopus 로고    scopus 로고
    • Conformation of CCAAT/enhancer-binding protein alpha dimers varies with intranuclear location in living cells
    • Schaufele F., Wang X., Liu X., Day R.N. Conformation of CCAAT/enhancer-binding protein alpha dimers varies with intranuclear location in living cells. J. Biol. Chem. 278:2003;10578-10587.
    • (2003) J. Biol. Chem. , vol.278 , pp. 10578-10587
    • Schaufele, F.1    Wang, X.2    Liu, X.3    Day, R.N.4
  • 32
    • 0037416207 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations
    • Sekar R.B., Periasamy A. Fluorescence resonance energy transfer (FRET) microscopy imaging of live cell protein localizations. J. Cell Biol. 160:2003;629-633.
    • (2003) J. Cell Biol. , vol.160 , pp. 629-633
    • Sekar, R.B.1    Periasamy, A.2
  • 33
    • 0026501444 scopus 로고
    • Multipotent neural cell lines can engraft and participate in development of mouse cerebellum
    • Snyder E.Y., Deitcher D.L., Walsh C., Arnold-Aldea S., Hartwieg E.A., Cepko C.L. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell. 68:1992;33-51.
    • (1992) Cell , vol.68 , pp. 33-51
    • Snyder, E.Y.1    Deitcher, D.L.2    Walsh, C.3    Arnold-Aldea, S.4    Hartwieg, E.A.5    Cepko, C.L.6
  • 36
    • 0032879437 scopus 로고    scopus 로고
    • Membrane filter assay for detection of amyloid-like polyglutamine- containing protein aggregates
    • Wanker E.E., Scherzinger E., Heiser V., Sittler A., Eickhoff H., Lehrach H. Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates. Methods Enzymol. 309:1999;375-386.
    • (1999) Methods Enzymol. , vol.309 , pp. 375-386
    • Wanker, E.E.1    Scherzinger, E.2    Heiser, V.3    Sittler, A.4    Eickhoff, H.5    Lehrach, H.6
  • 38
    • 0035894659 scopus 로고    scopus 로고
    • Glucocorticoid modulation of androgen receptor nuclear aggregation and cellular toxicity is associated with distinct forms of soluble expanded polyglutamine protein
    • Welch W.J., Diamond M.I. Glucocorticoid modulation of androgen receptor nuclear aggregation and cellular toxicity is associated with distinct forms of soluble expanded polyglutamine protein. Hum. Mol. Genet. 10:2001;3063-3074.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 3063-3074
    • Welch, W.J.1    Diamond, M.I.2
  • 39
    • 0034646426 scopus 로고    scopus 로고
    • Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease
    • Wyttenbach A., Carmichael J., Swartz J., Furlong R.A., Narain Y., Rankin J., Rubinsztein D.C. Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease. Proc. Natl. Acad. Sci. USA. 97:2000;2898-2903.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 2898-2903
    • Wyttenbach, A.1    Carmichael, J.2    Swartz, J.3    Furlong, R.A.4    Narain, Y.5    Rankin, J.6    Rubinsztein, D.C.7
  • 40
    • 0034181706 scopus 로고    scopus 로고
    • Confirmation of primary active substances from high throughput screening of chemical and biological populations: A statistical approach and practical considerations
    • Zhang J.H., Chung T.D., Oldenburg K.R. Confirmation of primary active substances from high throughput screening of chemical and biological populations. a statistical approach and practical considerations J. Comb. Chem. 2:2000;258-265.
    • (2000) J. Comb. Chem. , vol.2 , pp. 258-265
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3


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