-
1
-
-
0030612740
-
PPARgamma induces cell cycle withdrawal: Inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A
-
Altiok, S., Xu, M., and Spiegelman, B. M. (1997). PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev. 11, 1987-1998.
-
(1997)
Genes Dev.
, vol.11
, pp. 1987-1998
-
-
Altiok, S.1
Xu, M.2
Spiegelman, B.M.3
-
2
-
-
0032489437
-
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)
-
Aoyama, T., Peters, J. M., Iritani, N., Nakajima, T., Furihata, K., Hashimoto, T., and Gonzalez, F. J. (1998). Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J. Biol. Chem. 273, 5678-5684.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5678-5684
-
-
Aoyama, T.1
Peters, J.M.2
Iritani, N.3
Nakajima, T.4
Furihata, K.5
Hashimoto, T.6
Gonzalez, F.J.7
-
3
-
-
0028172089
-
Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis
-
Ashby, J., Brady, A., Elcombe, C. R., Elliott, B. M., Ishmael, J., Odum, J., Tugwood, J. D., Kettle, S., and Purchase, I. F. (1994). Mechanistically-based human hazard assessment of peroxisome proliferator-induced hepatocarcinogenesis. Hum. Exp. Toxicol 13(Suppl. 2), S1-117.
-
(1994)
Hum. Exp. Toxicol
, vol.13
, Issue.SUPPL. 2
-
-
Ashby, J.1
Brady, A.2
Elcombe, C.R.3
Elliott, B.M.4
Ishmael, J.5
Odum, J.6
Tugwood, J.D.7
Kettle, S.8
Purchase, I.F.9
-
4
-
-
0030747895
-
Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: No alteration in adipose tissue of obese and NIDDM patients
-
Auboeuf, D., Rieusset, J., Fajas, L., Vallier, P., Frering, V., Riou, J. P., Staels, B., Auwerx, J., Laville, M., and Vidal, H. (1997). Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 48, 1319-1327.
-
(1997)
Diabetes
, vol.48
, pp. 1319-1327
-
-
Auboeuf, D.1
Rieusset, J.2
Fajas, L.3
Vallier, P.4
Frering, V.5
Riou, J.P.6
Staels, B.7
Auwerx, J.8
Laville, M.9
Vidal, H.10
-
5
-
-
0028826476
-
Delayed effects of ciprofibrate on rat liver peroxisomal properties and proto-oncogene expression
-
Bardot, O., Clemencet, M. C., Malki, M. C., and Latruffe, N. (1995). Delayed effects of ciprofibrate on rat liver peroxisomal properties and proto-oncogene expression. Biochem. Pharmacol. 50, 1001-1006.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 1001-1006
-
-
Bardot, O.1
Clemencet, M.C.2
Malki, M.C.3
Latruffe, N.4
-
6
-
-
0028208243
-
Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin
-
Bayly, A. C., Roberts, R. A., and Dive, C. (1994). Suppression of liver cell apoptosis in vitro by the non-genotoxic hepatocarcinogen and peroxisome proliferator nafenopin. J. Cell. Biol. 125, 197-203.
-
(1994)
J. Cell. Biol.
, vol.125
, pp. 197-203
-
-
Bayly, A.C.1
Roberts, R.A.2
Dive, C.3
-
7
-
-
0030776116
-
Dietary conjugated linoleic acid induces peroxisome-specific enzyme accumulation and ornithine decarboxylase activity in mouse liver
-
Belury, M. A., Moya-Camarena, S. Y., Liu, L.-L., and Vanden Heuvel, J. P. (1997). Dietary conjugated linoleic acid induces peroxisome-specific enzyme accumulation and ornithine decarboxylase activity in mouse liver. J. Nutr. Biochem. 8, 579-584.
-
(1997)
J. Nutr. Biochem.
, vol.8
, pp. 579-584
-
-
Belury, M.A.1
Moya-Camarena, S.Y.2
Liu, L.-L.3
Vanden Heuvel, J.P.4
-
8
-
-
0032135723
-
Comparison of dose-response relationships for induction of lipid metabolizing and growth regulatory genes by peroxisome proliferators in rat liver
-
Belury, M. A., Moya-Camarena, S. Y., Sun, H., Snyder, E., Davis II, J. W., Cunningham, M. L., and Vanden Heuvel, J. P. (1998). Comparison of dose-response relationships for induction of lipid metabolizing and growth regulatory genes by peroxisome proliferators in rat liver. Toxicol. Appl. Pharmacol. 151, 254-261.
-
(1998)
Toxicol. Appl. Pharmacol.
, vol.151
, pp. 254-261
-
-
Belury, M.A.1
Moya-Camarena, S.Y.2
Sun, H.3
Snyder, E.4
Davis J.W. II5
Cunningham, M.L.6
Vanden Heuvel, J.P.7
-
9
-
-
0001908284
-
Protection against cancer and heart disease by the dietary fat, conjugated linoleic acid: Potential mechanisms of action
-
Belury, M. A., and Vanden Heuvel, J. P. (1997). Protection against cancer and heart disease by the dietary fat, conjugated linoleic acid: Potential mechanisms of action. Nutr. Disease Update Journal, 1, 58-63.
-
(1997)
Nutr. Disease Update Journal
, vol.1
, pp. 58-63
-
-
Belury, M.A.1
Vanden Heuvel, J.P.2
-
10
-
-
0027763648
-
Hepatic peroxisome proliferation in rodents and its significance for humans
-
Bentley, P., Calder, I., Elcombe, C., Grasso, P., Stringer, D., and Wiegand, H. J. (1993). Hepatic peroxisome proliferation in rodents and its significance for humans. Food Chem. Toxicol. 31, 857-907.
-
(1993)
Food Chem. Toxicol.
, vol.31
, pp. 857-907
-
-
Bentley, P.1
Calder, I.2
Elcombe, C.3
Grasso, P.4
Stringer, D.5
Wiegand, H.J.6
-
11
-
-
0029745382
-
Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: Binding and activation correlate with antidiabetic actions in db/db mice
-
Berger, J., Bailey, P., Biswas, C., Cullinan, C. A., Doebber, T. W., Hayes, N. S., Saperstein, R., Smith, R. G., and Leibowitz, M. D. (1996). Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: Binding and activation correlate with antidiabetic actions in db/db mice. Endocrinology 137, 4189-4195.
-
(1996)
Endocrinology
, vol.137
, pp. 4189-4195
-
-
Berger, J.1
Bailey, P.2
Biswas, C.3
Cullinan, C.A.4
Doebber, T.W.5
Hayes, N.S.6
Saperstein, R.7
Smith, R.G.8
Leibowitz, M.D.9
-
12
-
-
77957180019
-
Comparison of the effects of Wyeth-14,643 in Crl:CD BR and Fisher-344 rats
-
Biegel, L. B., Hurtt, M. E., Frame, S. R., Applegate, M., O'Conner, J. C., and Cook, J. C. (1992). Comparison of the effects of Wyeth-14,643 in Crl:CD BR and Fisher-344 rats. Fundam. Appl. Toxicol. 19, 590-597.
-
(1992)
Fundam. Appl. Toxicol.
, vol.19
, pp. 590-597
-
-
Biegel, L.B.1
Hurtt, M.E.2
Frame, S.R.3
Applegate, M.4
O'Conner, J.C.5
Cook, J.C.6
-
13
-
-
0031417341
-
Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643
-
Bojes, H. K., Germolec, D. R., Simeonova, P., Bruccoleri, A., Schoonhoven, R., Luster, M. I., and Thurman, R. G. (1997). Antibodies to tumor necrosis factor alpha prevent increases in cell replication in liver due to the potent peroxisome proliferator, WY-14,643. Carcinogenesis 18, 669-674.
-
(1997)
Carcinogenesis
, vol.18
, pp. 669-674
-
-
Bojes, H.K.1
Germolec, D.R.2
Simeonova, P.3
Bruccoleri, A.4
Schoonhoven, R.5
Luster, M.I.6
Thurman, R.G.7
-
14
-
-
0030047806
-
Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
-
Braissant, O., Foufelle, F., Scotto, C., Dauca, M., and Wahli, W. (1996). Differential expression of peroxisome proliferator-activated receptors (PPARs): Tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137, 354-366.
-
(1996)
Endocrinology
, vol.137
, pp. 354-366
-
-
Braissant, O.1
Foufelle, F.2
Scotto, C.3
Dauca, M.4
Wahli, W.5
-
15
-
-
13144283625
-
Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library
-
Brown, P. J., Smith-Oliver, T. A., Charifson, P. S., Tomkinson, N. C., Fivush, A. M., Sternbach, D. D., Wade, L. E., Orband-Miller, L., Parks, D. J., Blanchard, S. G., Kliewer, S. A., Lehmann, J. M., and Willson, T. M. (1997). Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library. Chem. Biol. 4, 909-918.
-
(1997)
Chem. Biol.
, vol.4
, pp. 909-918
-
-
Brown, P.J.1
Smith-Oliver, T.A.2
Charifson, P.S.3
Tomkinson, N.C.4
Fivush, A.M.5
Sternbach, D.D.6
Wade, L.E.7
Orband-Miller, L.8
Parks, D.J.9
Blanchard, S.G.10
Kliewer, S.A.11
Lehmann, J.M.12
Willson, T.M.13
-
16
-
-
0025561032
-
Differential proto-oncogene mRNA induction from rats treated with peroxisome proliferators
-
Cherkaoui-Malki, M., Lone, Y. C., Corral-Debrinski, M., and Latruffe, N. (1990). Differential proto-oncogene mRNA induction from rats treated with peroxisome proliferators. Biochem. Biophys. Res. Commun. 173, 855-861.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 855-861
-
-
Cherkaoui-Malki, M.1
Lone, Y.C.2
Corral-Debrinski, M.3
Latruffe, N.4
-
17
-
-
0031439111
-
p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha
-
Dowell, P., Ishmael, J. E., Avram, D., Peterson, V. J., Nevrivy, D. J., and Leid, M. (1997). p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha. J. Biol Chem. 272, 33435-33443.
-
(1997)
J. Biol Chem.
, vol.272
, pp. 33435-33443
-
-
Dowell, P.1
Ishmael, J.E.2
Avram, D.3
Peterson, V.J.4
Nevrivy, D.J.5
Leid, M.6
-
18
-
-
0026517010
-
Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors
-
Dreyer, C., Krey, G., Keller, H., Givel, F., Helftenbein, G., and Wahli, W. (1992). Control of the peroxisomal beta-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68, 879-887.
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, C.1
Krey, G.2
Keller, H.3
Givel, F.4
Helftenbein, G.5
Wahli, W.6
-
19
-
-
0023913120
-
The steroid and thyroid hormone receptor superfamily
-
Evans, R. M. (1988). The steroid and thyroid hormone receptor superfamily. Science 240, 889-895.
-
(1988)
Science
, vol.240
, pp. 889-895
-
-
Evans, R.M.1
-
20
-
-
0030835678
-
The organization, promoter analysis, and expression of the human PPARgamma gene
-
Fajas, L., Auboeuf, D., Raspe, E., Schoonjans, K., Lefebvre, A. M., Saladin, R., Najib, J., Laville, M., Fruchart, J. C., Deeb, S., Vidal-Puig, A., Flier, J., Briggs, M. R., Staels, B., Vidal, H., and Auwerx, J. (1997). The organization, promoter analysis, and expression of the human PPARgamma gene. J. Biol. Chem. 272, 18779-18789.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18779-18789
-
-
Fajas, L.1
Auboeuf, D.2
Raspe, E.3
Schoonjans, K.4
Lefebvre, A.M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
21
-
-
0020628062
-
Fenofibrate and human liver. Lack of proliferation of peroxisomes
-
Gariot, P., Barrat, E., Mejean, L., Pointel, J. P., Drouin, P., and Debry, G. (1983). Fenofibrate and human liver. Lack of proliferation of peroxisomes. Arch. Toxicol. 53, 151-163.
-
(1983)
Arch. Toxicol.
, vol.53
, pp. 151-163
-
-
Gariot, P.1
Barrat, E.2
Mejean, L.3
Pointel, J.P.4
Drouin, P.5
Debry, G.6
-
22
-
-
0021174837
-
Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella
-
Glauert, H. P., Reddy, J. K., Kennan, W. S., Sattler, G. L., Rao, V. S., and Pitot, H. C. (1984). Effect of hypolipidemic peroxisome proliferators on unscheduled DNA synthesis in cultured hepatocytes and on mutagenesis in Salmonella. Cancer Lett. 24, 147-156.
-
(1984)
Cancer Lett.
, vol.24
, pp. 147-156
-
-
Glauert, H.P.1
Reddy, J.K.2
Kennan, W.S.3
Sattler, G.L.4
Rao, V.S.5
Pitot, H.C.6
-
23
-
-
0026551309
-
Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
-
Gottlicher, M., Widmark, E., Li, Q., and Gustafsson, J. A. (1992). Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 89, 4654-4657.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4654-4657
-
-
Gottlicher, M.1
Widmark, E.2
Li, Q.3
Gustafsson, J.A.4
-
24
-
-
0032030951
-
Member of the peroxisome proliferator-activated receptor family of transcription factors is differentially expressed in oligodendrocytes
-
Granneman, J., Skoff, R., and Yang, X. (1998). Member of the peroxisome proliferator-activated receptor family of transcription factors is differentially expressed in oligodendrocytes. Journal of Neuroscience Research 51, 563-573.
-
(1998)
Journal of Neuroscience Research
, vol.51
, pp. 563-573
-
-
Granneman, J.1
Skoff, R.2
Yang, X.3
-
25
-
-
0026704218
-
Peroxisome proliferators: A model for receptor mediated carcinogenesis
-
Green, S. (1992). Peroxisome proliferators: A model for receptor mediated carcinogenesis. Cancer Surv. 14, 221-232.
-
(1992)
Cancer Surv.
, vol.14
, pp. 221-232
-
-
Green, S.1
-
26
-
-
0030792539
-
Trans-differentiation of myoblasts to adipoblasts: Triggering effects of fatty acids and thiazolidinediones
-
Grimaldi, P. A., Teboul, L., Inadera, H., Gaillard, D., and Amri, E. Z. (1997). Trans-differentiation of myoblasts to adipoblasts: Triggering effects of fatty acids and thiazolidinediones. Prostaglandins Leukot. Essent. Fatty Acids 57, 71-75.
-
(1997)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.57
, pp. 71-75
-
-
Grimaldi, P.A.1
Teboul, L.2
Inadera, H.3
Gaillard, D.4
Amri, E.Z.5
-
27
-
-
0031945627
-
Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARα
-
Hanley, K., Yan, J., He, S. S., Friedman, M., Elias, P. M., Bikle, D. D., Williams, M. L., and Feingold, K. R. (1998). Keratinocyte differentiation is stimulated by activators of the nuclear hormone receptor PPARα. J. Invest. Dermatol. 110, 368-375.
-
(1998)
J. Invest. Dermatol.
, vol.110
, pp. 368-375
-
-
Hanley, K.1
Yan, J.2
He, S.S.3
Friedman, M.4
Elias, P.M.5
Bikle, D.D.6
Williams, M.L.7
Feingold, K.R.8
-
28
-
-
0028309738
-
Association of peroxisome proliferator-activated receptor and Hsp72
-
Huang, Q., Alvares, K., Chu, R., Bradfield, C. A., and Reddy, J. K. (1994). Association of peroxisome proliferator-activated receptor and Hsp72. J. Biol. Chem. 269, 8493-8497.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 8493-8497
-
-
Huang, Q.1
Alvares, K.2
Chu, R.3
Bradfield, C.A.4
Reddy, J.K.5
-
29
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
Issemann, I., and Green, S. (1990). Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators [see Comments]. Nature 347, 645-650.
-
(1990)
Nature
, vol.347
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
30
-
-
0026545711
-
A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation?
-
Issemann, I., Prince, R., Tugwood, J., and Green, S. (1992). A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation? Biochem. Soc. Trans. 20, 824-827.
-
(1992)
Biochem. Soc. Trans.
, vol.20
, pp. 824-827
-
-
Issemann, I.1
Prince, R.2
Tugwood, J.3
Green, S.4
-
31
-
-
0031409897
-
Induction of replicative DNA synthesis and PPAR alpha-dependent gene transcription by Wy-14 643 in primary rat hepatocyte and non-parenchymal cell co-cultures
-
Karam, W. G., and Ghanayem, B. I. (1997). Induction of replicative DNA synthesis and PPAR alpha-dependent gene transcription by Wy-14 643 in primary rat hepatocyte and non-parenchymal cell co-cultures. Carcinogenesis 18, 2077-2083.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2077-2083
-
-
Karam, W.G.1
Ghanayem, B.I.2
-
32
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
-
Kliewer, S. A., Umesono, K., Noonan, D. J., Heyman, R. A., and Evans, R. M. (1992). Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358, 771-774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
-
33
-
-
0028972026
-
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation
-
Kliewer, S. A., Lenhard, J. M., Willson, T. M., Patel, I., Morris, D. C., and Lehmann, J. M. (1995). A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83, 813-819.
-
(1995)
Cell
, vol.83
, pp. 813-819
-
-
Kliewer, S.A.1
Lenhard, J.M.2
Willson, T.M.3
Patel, I.4
Morris, D.C.5
Lehmann, J.M.6
-
34
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
-
Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., and Lehmann, J. M. (1997). Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proc. Natl. Acad. Sci. USA 94, 4318-4323.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
Sundseth, S.S.2
Jones, S.A.3
Brown, P.J.4
Wisely, G.B.5
Koble, C.S.6
Devchand, P.7
Wahli, W.8
Willson, T.M.9
Lenhard, J.M.10
Lehmann, J.M.11
-
35
-
-
0030985318
-
Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay
-
Krey, G., Braissant, O., L'Horset, F., Kalkhoven, E., Perroud, M., Parker, M. G., and Wahli, W. (1997). Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay. Mol. Endocrinol. 11, 779-791.
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 779-791
-
-
Krey, G.1
Braissant, O.2
L'Horset, F.3
Kalkhoven, E.4
Perroud, M.5
Parker, M.G.6
Wahli, W.7
-
36
-
-
0027265355
-
Activation of immediate-early gene expression by peroxisome proliferators in vitro
-
Ledwith, B. J., Manam, S., Troilo, P., Joslyn, D. J., Galloway, S. M., and Nichols, W. W. (1993). Activation of immediate-early gene expression by peroxisome proliferators in vitro. Mol. Carcinog. 8, 20-27.
-
(1993)
Mol. Carcinog.
, vol.8
, pp. 20-27
-
-
Ledwith, B.J.1
Manam, S.2
Troilo, P.3
Joslyn, D.J.4
Galloway, S.M.5
Nichols, W.W.6
-
37
-
-
0030013157
-
Growth regulation by peroxisome proliferators: Opposing activities in early and late G1
-
Ledwith, B. J., Johnson, T. E., Wagner, L. K., Pauley, C. J., Manam, S., Galloway, S. M., and Nichols, W. W. (1996). Growth regulation by peroxisome proliferators: Opposing activities in early and late G1. Cancer Res. 56, 3257-3264.
-
(1996)
Cancer Res.
, vol.56
, pp. 3257-3264
-
-
Ledwith, B.J.1
Johnson, T.E.2
Wagner, L.K.3
Pauley, C.J.4
Manam, S.5
Galloway, S.M.6
Nichols, W.W.7
-
38
-
-
0031022340
-
Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells
-
Ledwith, B. J., Pauley, C. J., Wagner, L. K., Rokos, C. L., Alberts, D. W., and Manam, S. (1997). Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells. J. Biol. Chem. 272, 3707-3714.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3707-3714
-
-
Ledwith, B.J.1
Pauley, C.J.2
Wagner, L.K.3
Rokos, C.L.4
Alberts, D.W.5
Manam, S.6
-
39
-
-
0028997684
-
Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators
-
Lee, S. S., Pineau, T., Drago, J., Lee, E. J., Owens, J. W., Kroetz, D. L., Fernandez-Salguero, P. M., Westphal, H., and Gonzalez, F. J. (1995). Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators. Mol. Cell. Biol. 15, 3012-3022.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drago, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
40
-
-
0029016829
-
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
-
Lehmann, J. M., Moore, L. B., Smith-Oliver, T. A., Wilkison, W. O., Willson, T. M., and Kliewer, S. A. (1995). An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J. Biol. Chem. 270, 12953-12956.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12953-12956
-
-
Lehmann, J.M.1
Moore, L.B.2
Smith-Oliver, T.A.3
Wilkison, W.O.4
Willson, T.M.5
Kliewer, S.A.6
-
41
-
-
0024509605
-
Biochemical mechanisms of induction of hepatic peroxisome proliferation
-
Lock, E. A., Mitchell, A. M., and Elcombe, C. R. (1989). Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu. Rev. Pharmacol. Toxicol. 29, 145-163.
-
(1989)
Annu. Rev. Pharmacol. Toxicol.
, vol.29
, pp. 145-163
-
-
Lock, E.A.1
Mitchell, A.M.2
Elcombe, C.R.3
-
42
-
-
0024241608
-
Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats
-
Marsman, D. S., Cattley, R. C., Conway, J. G., and Popp, J. A. (1988). Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Cancer Res. 48, 6739-6744.
-
(1988)
Cancer Res.
, vol.48
, pp. 6739-6744
-
-
Marsman, D.S.1
Cattley, R.C.2
Conway, J.G.3
Popp, J.A.4
-
43
-
-
0029931972
-
The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling
-
Miyata, K. S., McCaw, S. E., Patel, H. V., Rachubinski, R. A., and Capone, J. P. (1996). The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling. J. Biol. Chem. 271, 9189-9192.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9189-9192
-
-
Miyata, K.S.1
McCaw, S.E.2
Patel, H.V.3
Rachubinski, R.A.4
Capone, J.P.5
-
44
-
-
0031558788
-
The antidiabetic agent thiazolidinedione stimulates the interaction between PPAR gamma and CBP
-
Mizukami, J., and Taniguchi, T. (1997). The antidiabetic agent thiazolidinedione stimulates the interaction between PPAR gamma and CBP. Biochem. Biophys. Res. Commun. 240, 61-64.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.240
, pp. 61-64
-
-
Mizukami, J.1
Taniguchi, T.2
-
45
-
-
0026100678
-
Peroxisome proliferation and nongenotoxic carcinogenesis: Commentary on a symposium
-
Moody, D. E., Reddy, J. K., Lake, B. G., Popp, J. A., and Reese, D. H. (1991). Peroxisome proliferation and nongenotoxic carcinogenesis: commentary on a symposium. Fundam. Appl. Toxicol. 16, 233-248.
-
(1991)
Fundam. Appl. Toxicol.
, vol.16
, pp. 233-248
-
-
Moody, D.E.1
Reddy, J.K.2
Lake, B.G.3
Popp, J.A.4
Reese, D.H.5
-
46
-
-
0026730908
-
The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome p450 fatty acid omega-hydroxylase, by clofibric acid
-
Muerhoff, A. S., Griffin, K. J., and Johnson, E. F. (1992). The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid omega-hydroxylase, by clofibric acid. J. Biol. Chem. 267, 19051-19053.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 19051-19053
-
-
Muerhoff, A.S.1
Griffin, K.J.2
Johnson, E.F.3
-
47
-
-
0031418657
-
Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
-
Peters, J. M., Cattley, R. C., and Gonzalez, F. J. (1997). Role of PPAR alpha in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis 18, 2029-2033.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
Gonzalez, F.J.3
-
48
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice
-
Peters, J. M., Hennuyer, N., Staels, B., Fruchart, J. C., Fievet, C., Gonzalez, F. J., and Auwerx, J. (1997). Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice. J. Biol. Chem. 272, 27307-27312.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.C.4
Fievet, C.5
Gonzalez, F.J.6
Auwerx, J.7
-
49
-
-
0029999619
-
Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs
-
Pineau, T., Hudgins, W. R., Liu, L., Chen, L. C., Sher, T., Gonzalez, F. J., and Samid, D. (1996). Activation of a human peroxisome proliferator-activated receptor by the antitumor agent phenylacetate and its analogs. Biochem. Pharmacol. 52, 659-667.
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 659-667
-
-
Pineau, T.1
Hudgins, W.R.2
Liu, L.3
Chen, L.C.4
Sher, T.5
Gonzalez, F.J.6
Samid, D.7
-
50
-
-
0016709214
-
Hepatic peroxisome proliferation: Induction by two novel compounds structurally unrelated to clofibrate
-
Reddy, J. K., and Krishnakantha, T. P. (1975). Hepatic peroxisome proliferation: induction by two novel compounds structurally unrelated to clofibrate. Science 190, 787-789.
-
(1975)
Science
, vol.190
, pp. 787-789
-
-
Reddy, J.K.1
Krishnakantha, T.P.2
-
51
-
-
0021051308
-
Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans
-
Reddy, J. K., and Lalwani, N. D. (1983). Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol. 12, 1-58.
-
(1983)
Crit. Rev. Toxicol.
, vol.12
, pp. 1-58
-
-
Reddy, J.K.1
Lalwani, N.D.2
-
52
-
-
0017571584
-
Malignant tumors in rats fed nafenopin, a hepatic peroxisome proliferator
-
Reddy, J. K., and Rao, M. S. (1977). Malignant tumors in rats fed nafenopin, a hepatic peroxisome proliferator. J. Natl. Cancer Inst. 59, 1645-1650.
-
(1977)
J. Natl. Cancer Inst.
, vol.59
, pp. 1645-1650
-
-
Reddy, J.K.1
Rao, M.S.2
-
53
-
-
0030462771
-
Non-genotoxic hepatocarcinogenesis: Suppression of apoptosis by peroxisome proliferators
-
Roberts, R. A. (1996). Non-genotoxic hepatocarcinogenesis: Suppression of apoptosis by peroxisome proliferators. Ann. N. Y. Acad. Sci. 804, 588-611.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.804
, pp. 588-611
-
-
Roberts, R.A.1
-
54
-
-
0031819433
-
Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPARalpha)
-
Roberts, R. A., James, N. H., Woodyatt, N. J., Macdonald, N., and Tugwood, J. D. (1998). Evidence for the suppression of apoptosis by the peroxisome proliferator activated receptor alpha (PPARalpha). Carcinogenesis 19, 43-48.
-
(1998)
Carcinogenesis
, vol.19
, pp. 43-48
-
-
Roberts, R.A.1
James, N.H.2
Woodyatt, N.J.3
Macdonald, N.4
Tugwood, J.D.5
-
55
-
-
85033543738
-
Perturbation of the mitosis/apoptosis balance: A fundamental mechanism in toxicology
-
Roberts, R. A., Nebert, D. W., Hickman, J. A., Richburg, J. H., and Goldsworthy, T. L. (1997). Perturbation of the mitosis/apoptosis balance: a fundamental mechanism in toxicology. Fundam. Appl. Toxicol. 38, 107-115.
-
(1997)
Fundam. Appl. Toxicol.
, vol.38
, pp. 107-115
-
-
Roberts, R.A.1
Nebert, D.W.2
Hickman, J.A.3
Richburg, J.H.4
Goldsworthy, T.L.5
-
56
-
-
0030965266
-
Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells
-
Rokos, C. L., and Ledwith, B. J. (1997). Peroxisome proliferators activate extracellular signal-regulated kinases in immortalized mouse liver cells. J. Biol. Chem. 272, 13452-13457.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13452-13457
-
-
Rokos, C.L.1
Ledwith, B.J.2
-
57
-
-
0031419250
-
Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators
-
Rose, M. L., Germolec, D. R., Schoonhoven, R., and Thurman, R. G. (1997). Kupffer cells are causally responsible for the mitogenic effect of peroxisome proliferators. Carcinogenesis 18, 1453-1456.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1453-1456
-
-
Rose, M.L.1
Germolec, D.R.2
Schoonhoven, R.3
Thurman, R.G.4
-
58
-
-
0028827635
-
Suppression of rat glutathione transferase P expression by peroxisome proliferators: Interaction between Jun and peroxisome proliferator-activated receptor alpha
-
Sakai, M., Matsushima-Hibiya, Y., Nishizawa, M., and Nishi, S. (1995). Suppression of rat glutathione transferase P expression by peroxisome proliferators: interaction between Jun and peroxisome proliferator-activated receptor alpha. Cancer Res. 55, 5370-5376.
-
(1995)
Cancer Res.
, vol.55
, pp. 5370-5376
-
-
Sakai, M.1
Matsushima-Hibiya, Y.2
Nishizawa, M.3
Nishi, S.4
-
59
-
-
0030794057
-
Peroxisome proliferator-activated receptors, orphans with ligands and functions
-
Schoonjans, K., Martin, G., Staels, B., and Auwerx, J. (1997). Peroxisome proliferator-activated receptors, orphans with ligands and functions. Curr. Opin. Lipidol. 8, 159-166.
-
(1997)
Curr. Opin. Lipidol.
, vol.8
, pp. 159-166
-
-
Schoonjans, K.1
Martin, G.2
Staels, B.3
Auwerx, J.4
-
60
-
-
0030602866
-
The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation
-
Schoonjans, K., Staels, B., and Auwerx, J. (1996). The peroxisome proliferator activated receptors (PPARS) and their effects on lipid metabolism and adipocyte differentiation. Biochim. Biophys. Acta. 1302, 93-109.
-
(1996)
Biochim. Biophys. Acta.
, vol.1302
, pp. 93-109
-
-
Schoonjans, K.1
Staels, B.2
Auwerx, J.3
-
61
-
-
0027191040
-
cDna cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
-
Sher, T., Yi, H. F., McBride, O. W., and Gonzalez, F. J. (1993). cDna cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor. Biochemistry 32, 5598-5604.
-
(1993)
Biochemistry
, vol.32
, pp. 5598-5604
-
-
Sher, T.1
Yi, H.F.2
McBride, O.W.3
Gonzalez, F.J.4
-
62
-
-
0030759196
-
PPAR gamma and the control of adipogenesis
-
Spiegelman, B. M., Hu, E., Kim, J. B., and Brun, R. (1997). PPAR gamma and the control of adipogenesis. Biochimie 79, 111-112.
-
(1997)
Biochimie
, vol.79
, pp. 111-112
-
-
Spiegelman, B.M.1
Hu, E.2
Kim, J.B.3
Brun, R.4
-
63
-
-
0030057564
-
Regulation of peroxisome proliferator-activated receptor-alpha mRNA in rat liver
-
Sterchele, P. F., Sun, H., Peterson, R. E., and Vanden Heuvel, J. P. (1996). Regulation of peroxisome proliferator-activated receptor-alpha mRNA in rat liver. Arch. Biochem. Biophys. 326, 281-289.
-
(1996)
Arch. Biochem. Biophys.
, vol.326
, pp. 281-289
-
-
Sterchele, P.F.1
Sun, H.2
Peterson, R.E.3
Vanden Heuvel, J.P.4
-
64
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
-
[published erratum appears in Cell 1995 Mar 24;80(6): following 957]
-
Tontonoz, P., Hu, E., and Spiegelman, B. M. (1994). Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor [published erratum appears in Cell 1995 Mar 24;80(6): following 957]. Cell 79, 1147-1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
65
-
-
0032540012
-
PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz, P., Nagy, L., Alvarez, J. G. A., Thomazy, V. A., and Evans, R. M. (1998). PPARγ promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 93, 241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.A.3
Thomazy, V.A.4
Evans, R.M.5
-
66
-
-
0030454445
-
Peroxisome proliferator-activated receptors: Structures and function
-
Tugwood, J. D., Aldridge, T. C., Lambe, K. G., Macdonald, N., and Woodyatt, N. J. (1996). Peroxisome proliferator-activated receptors: structures and function. Ann. N. Y. Acad. Sci. 804, 252-265.
-
(1996)
Ann. N. Y. Acad. Sci.
, vol.804
, pp. 252-265
-
-
Tugwood, J.D.1
Aldridge, T.C.2
Lambe, K.G.3
Macdonald, N.4
Woodyatt, N.J.5
-
67
-
-
0026541591
-
The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
-
Tugwood, J. D., Issemann, I., Anderson, R. G., Bundell, K. R., McPheat, W. L., and Green, S. (1992). The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. Embo. J. 11, 433-439.
-
(1992)
Embo. J.
, vol.11
, pp. 433-439
-
-
Tugwood, J.D.1
Issemann, I.2
Anderson, R.G.3
Bundell, K.R.4
McPheat, W.L.5
Green, S.6
-
68
-
-
0030273512
-
Perfluorodecanoic acid as a useful pharmacologic tool for the study of peroxisome proliferation
-
Vanden Heuvel, J. P. (1996). Perfluorodecanoic acid as a useful pharmacologic tool for the study of peroxisome proliferation. Gen. Pharmacol. 27, 1123-1129.
-
(1996)
Gen. Pharmacol.
, vol.27
, pp. 1123-1129
-
-
Vanden Heuvel, J.P.1
-
69
-
-
0031793057
-
Identification of a novel peroxisome proliferator responsive cDNA isolated from rat hepatocytes as the zinc-finger protein ZFP-37
-
Vanden Heuvel, J. P., Holden, P., Tugwood, J., Ingle, C., Yen, W., Galjart, N., and Greenlee, W. F. (1998). Identification of a novel peroxisome proliferator responsive cDNA isolated from rat hepatocytes as the zinc-finger protein ZFP-37. Toxicol. Appl. Pharmacol 152, 107-118.
-
(1998)
Toxicol. Appl. Pharmacol
, vol.152
, pp. 107-118
-
-
Vanden Heuvel, J.P.1
Holden, P.2
Tugwood, J.3
Ingle, C.4
Yen, W.5
Galjart, N.6
Greenlee, W.F.7
-
70
-
-
0027265115
-
Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene
-
Zhang, B., Marcus, S. L., Miyata, K. S., Subramani, S., Capone, J. P., and Rachubinski, R. A. (1993). Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene. J. Biol. Chem. 268, 12939-12945.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12939-12945
-
-
Zhang, B.1
Marcus, S.L.2
Miyata, K.S.3
Subramani, S.4
Capone, J.P.5
Rachubinski, R.A.6
-
71
-
-
0030341454
-
Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma
-
Zhu, Y., Qi, C., Calandra, C., Rao, M. S., and Reddy, J. K. (1996). Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma. Gene Expr. 6, 185-195.
-
(1996)
Gene Expr.
, vol.6
, pp. 185-195
-
-
Zhu, Y.1
Qi, C.2
Calandra, C.3
Rao, M.S.4
Reddy, J.K.5
-
72
-
-
0030771856
-
Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
-
Zhu, Y., Qi, C., Jain, S., Rao, M. S., and Reddy, J. K. (1997). Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor. J. Biol. Chem. 272, 25500-25506.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25500-25506
-
-
Zhu, Y.1
Qi, C.2
Jain, S.3
Rao, M.S.4
Reddy, J.K.5
|