IκB Kinase, a Molecular Target for Inhibition by 4-Hydroxy-2-nonenal

Journal of Biological Chemistry

Volumn 276, Issue 21, 2001, Pages 18223-18228

  Ji, Chuan ^a   Kozak, Kevin R ^a   Marnett, Lawrence J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CARCINOGENS; CELL CULTURE; CHEMICAL ACTIVATION; CHEMICAL MODIFICATION; DEGRADATION; DNA; ENZYME INHIBITION;

PHOSPHORYLATION; PROTEOLYSIS;

BIOCHEMISTRY;

4 HYDROXYNONENAL; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; TRANSCRIPTION FACTOR; 4-HYDROXY-2-NONENAL; ALDEHYDE; CHUK PROTEIN, HUMAN; CYSTEINE PROTEINASE INHIBITOR; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; ARTICLE; CELL STIMULATION; COVALENT BOND; DNA ADDUCT; DNA DAMAGE; GENE TARGETING; HUMAN; HUMAN CELL; MOLECULAR GENETICS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; REPORTER GENE; TRANSACTIVATION; WESTERN BLOTTING; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ALDEHYDES; CYSTEINE PROTEINASE INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; I-KAPPA B KINASE; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; TUMOR CELLS, CULTURED;

EID: 0035947678     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101266200     Document Type: Article

References (48)

1. Esterbauer, H., Schaur, R. J., and Zollner, H. (1991) Free Radic. Biol. Med. 11, 81-128
2. Esterbauer, H. (1993) Am. J. Clin. Nutr. 57, (suppl.) 779-785
3. Marnett, L. J. (1999) Mutat. Res. 424, 83-95
4. Chaudhary, A. K., Nokubo, M., Reddy, G. R., Yeola, S. N., Morrow, J. D., Blair, I. A., and Marnett, L. J. (1994) Science 265, 1580-1582
5. Nath, R. G., and Chung, F.-L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 7491-7495
6. Chung, F. L., Nath, R. G., Ocando, J., Nishikawa, A., and Zhang, L. (2000) Cancer Res. 60, 1507-1511
7. Ji, C., Rouzer, C. A., Marnett, L. J., and Pietenpol, J. A. (1998) Carcinogenesis 19, 1275-1283
8. Kirichenko, A., Li, L., Morandi, M. T., and Holian, A. (1996) Toxicol. Appl. Pharmacol. 141, 416-424
9. Kruman, I., Bruce-Keller, A. J., Bredesen, D., Waeg, G., and Mattson, M. P. (1997) J. Neurosci. 17, 5089-5100
10. Liu, W., Kato, M., Akhand, A. A., Hayakawa, A., Suzuki, H., Miyata, T., Kurokawa, K., Hotta, Y., Ishikawa, N., and Nakashima, I. (2000) J. Cell Sci. 113, 635-641
11. Fazio, V. M., Barrera, G., Martinotti, S., Farace, M. G., Giglioni, B., Frati, L., Manzari, V., and Dianzani, M. U. (1992) Cancer Res. 52, 4866-4871
12. Barrera, G., Martinotti, S., Fazio, V., Manzari, V., Paradisi, L., Parola, M., Frati, L., and Dianzani, M. U. (1987) Toxicol. Pathol. 15, 238-240
13. Schauenstein, E., Esterbauer, H., and Zollner, H. (1977) Aldehydes in Biological Systems: Their Natural Occurrence and Biological Activities, Piol Limited, London
14. Barrera, G., Pizzimenti, S., Serra, A., Ferretti, C., Fazio, V. M., Saglio, G., and Dianzani, M. U. (1996) Biochem. Biophys. Res. Commun. 227, 589-593
15. Soh, Y., Jeong, K. S., Lee, I. J., Bae, M. A., Kim, Y. C., and Song, B. J. (2000) Mol. Pharmacol. 58, 535-541
16. Parola, M., Robino, G., Marra, F., Pinzani, M., Bellomo, G., Leonarduzzi, G., Chiarugi, P., Camandola, S., Poli, G., Waeg, G., Gentilini, P., and Dianzani, M. U. (1998) J. Clin. Invest. 102, 1942-1950
17. Lenardo, M. J., and Baltimore, D. (1989) Cell 58, 227-229
18. Mercurio, F., and Manning, A. M. (1999) Oncogene 18, 6163-6171
19. Janssen-Heininger, Y. M., Poynter, M. E., and Baeuerle, P. A. (2000) Free Radic. Biol. Med. 28, 1317-1327
20. Muller, C. W., Rey, F. A., Sodeoka, M., Verdine, G. L., and Harrison, S. C. (1995) Nature 373, 311-317
21. Ghosh, G., van Duyne, G., Ghosh, S., and Sigler, P. B. (1995) Nature 373, 303-310
22. Karin, M. (1999) J. Biol. Chem. 274, 27339-27342
23. Brown, K., Gerstberger, S., Carlson, L., Franzoso, G., and Siebenlist, U. (1995) Science 267, 1485-1488
24. DiDonato, J., Mercurio, F., Rosette, C., Wu-Li, J., Suyang, H., Ghosh, S., and Karin, M. (1996) Mol. Cell. Biol. 16, 1295-1304
25. Alkalay, I., Yaron, A., Hatzubai, A., Orian, A., Ciechanover, A., and Ben-Neriah, Y. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 10599-10603
26. Beg, A. A., Finco, T. S., Nantermet, P. V., and Baldwin, A. S., Jr. (1993) Mol. Cell. Biol. 13, 3301-3310
27. Brown, K., Park, S., Kanno, T., Franzoso, G., and Siebenlist, U. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2532-2536
28. Regnier, C. H., Song, H. Y., Gao, X., Goeddel, D. V., Cao, Z., and Rothe, M. (1997) Cell 90, 373-383
29. Yin, M. J., Christerson, L. B., Yamamoto, Y., Kwak, Y. T., Xu, S., Mercurio, F., Barbosa, M., Cobb, M. H., and Gaynor, R. B. (1998) Cell 93, 875-884
30. Delhase, M., Hayakawa, M., Chen, Y., and Karin, M. (1999) Science 284, 309-313
31. Cordle, S. R., Donald, R., Read, M. A., and Hawiger, J. (1993) J. Biol. Chem. 268, 11803-11810
32. Henkel, T., Machleidt, T., Alkalay, I., Kronke, M., Ben-Neriah, Y., and Baeuerle, P. A. (1993) Nature 365, 182-185
33. Page, S., Fischer, C., Baumgartner, B., Haas, M., Kreusel, U., Loidl, G., Hayn, M., Ziegler-Heitbrock, H. W., Neumeier, D., and Brand, K. (1999) J. Biol. Chem. 274, 11611-11618
34. Imbert, V., Rupec, R. A., Livolsi, A., Pahl, H. L., Traenckner, E. B., Mueller-Dieckmann, C., Farahifar, D., Rossi, B., Auberger, P., Baeuerle, P. A., and Peyron, J. F. (1996) Cell 86, 787-798
35. Li, N., and Karin, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 13012-13017
36. Bender, K., Gottlicher, M., Whiteside, S., Rahmsdorf, H. J., and Herrlich, P. (1998) EMBO J. 17, 5170-5181
37. DiDonato, J. A., Hayakawa, M., Rothwarf, D. M., Zandi, E., and Karin, M. (1997) Nature 388, 548-554
38. Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J., Young, D. B., Barbosa, M., Mann, M., Manning, A., and Rao, A. (1997) Science 278, 860-866
39. Yamaoka, S., Courtois, G., Bessia, C., Whiteside, S. T., Weil, R., Agou, F., Kirk, H. E., Kay, R. J., and Israel, A. (1998) Cell 93, 1231-1240
40. Rothwarf, D. M., Zandi, E., Natoli, G., and Karin, M. (1998) Nature 395, 297-300
41. Nakano, H., Shindo, M., Sakon, S., Nishinaka, S., Mihara, M., Yagita, H., and Okumura, K. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3537-3542
42. Uchida, K., Shiraishi, M., Naito, Y., Torii, Y., Nakamura, Y., and Osawa, T. (1999) J. Biol. Chem. 274, 4909-4912
43. Yin, M. J., Yamamoto, Y., and Gaynor, R. B. (1998) Nature 396, 77-80
44. Yamamoto, Y., Yin, M. J., Lin, K. M., and Gaynor, R. B. (1999) J. Biol. Chem. 274, 27307-27314
45. Rossi, A., Kapahi, P., Natoli, G., Takahashi, T., Chen, Y., Karin, M., and Santoro, M. G. (2000) Nature 403, 103-108
46. Friguet, B., Stadtman, E. R., and Szweda, L. I. (1994) J. Biol. Chem. 269, 21639-21643
47. Castrillo, A., Diaz-Guerra, M. J., Hortelano, S., Martin-Sanz, P., and Bosca, L. (2000) Mol. Cell. Biol. 20, 1692-1698
48. Li, L., Hamilton, R. F., Jr., and Holian, A. (1999) Am. J. Physiol. 277, L550-L557