α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome

Free Radical Biology and Medicine

Volumn 50, Issue 12, 2011, Pages 1801-1811

  Shichiri, Mototada ^a,b   Yoshida, Yasukazu ^a   Ishida, Noriko ^a   Hagihara, Yoshihisa ^a   Iwahashi, Hitoshi ^a   Tamai, Hiroshi ^b   Niki, Etsuo ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Down syndrome; Free radicals; Lipid peroxidation; Oxidative stress; Ts65Dn mouse; Vitamin E

Indexed keywords

8 ISOPROSTAGLANDIN F2 ALPHA; ALPHA TOCOPHEROL; HYDROXY FATTY ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR DISORDER; BIRTH; BRAIN TISSUE; COGNITIVE DEFECT; CONCEPTION; CONTROLLED STUDY; DENTATE GYRUS; DIET SUPPLEMENTATION; DOWN SYNDROME; FEMALE; HIPPOCAMPUS; LEARNING DISORDER; LIFESPAN; LIPID PEROXIDATION; MALE; MAZE TEST; MOUSE; NEWBORN; NONHUMAN; PLASMA; PREGNANCY; PRIORITY JOURNAL; PUP (RODENT);

ALPHA-TOCOPHEROL; ANIMALS; ANIMALS, NEWBORN; BRAIN; COGNITION DISORDERS; DINOPROST; DISEASE MODELS, ANIMAL; DOWN SYNDROME; FATTY ACIDS, UNSATURATED; FEMALE; FREE RADICALS; HIPPOCAMPUS; HYDROXYCHOLESTEROLS; LIPID PEROXIDATION; MAZE LEARNING; MICE; MICE, NEUROLOGIC MUTANTS; OXIDATIVE STRESS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; SPACE PERCEPTION;

MUS;

EID: 79956146841     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.03.023     Document Type: Article

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