Rescue of anaemia and autoimmune responses in SOD1-deficient mice by transgenic expression of human SOD1 in erythrocytes

Biochemical Journal

Volumn 422, Issue 2, 2009, Pages 313-320

  Iuchi, Yoshihito ^a   Okada, Futoshi ^a   Takamiya, Rina ^b   Kibe, Noriko ^a   Tsunoda, Satoshi ^a   Nakajima, Osamu ^c   Toyoda, Kazuyo ^d   Nagae, Ritsuko ^d   Suematsu, Makoto ^b   Soga, Tomoyoshi ^b   Uchida, Koji ^d   Fujii, Junichi ^a  

^a YAMAGATA UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c YAMAGATA UNIVERSITY   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

Autoantibody; Oxidative stress; Superoxide dismutase; Transgenic rescue

Indexed keywords

4-HYDROXY-2-NONENAL; AUTOANTIBODIES; AUTOANTIBODY; BLOOD UREA; CARBON METABOLISM; CARBONIC ANHYDRASE II; CHARGE POTENTIALS; GLUCOSE METABOLISM; IMMUNE SYSTEMS; LIFE SPAN; LIPID PEROXIDATION; METABOLOMIC ANALYSIS; OXIDATION PRODUCTS; OXIDATIVE MODIFICATION; PENTOSE PHOSPHATE PATHWAY; REACTIVE OXYGEN SPECIES; RED BLOOD CELL; RENAL FUNCTIONS; SUPEROXIDE DISMUTASE; TRANSGENE; TRANSGENIC EXPRESSION; TRANSGENIC MICE; TRANSGENIC RESCUE;

ALDEHYDES; ANTIBODIES; ANTIGENS; BIOCHEMISTRY; BLOOD; GLUCOSE; METABOLISM; OXIDATION; OXIDATIVE STRESS; UREA; ZINC;

OXYGEN;

4 HYDROXYNONENAL; ACROLEIN; AUTOANTIBODY; CARBON; CARBONATE DEHYDRATASE II; COPPER ZINC SUPEROXIDE DISMUTASE; NITROGEN; PENTOSE PHOSPHATE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR GATA 1; UREA; SUPEROXIDE DISMUTASE;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; ERYTHROCYTE DISORDER; GENE EXPRESSION REGULATION; GLUCOSE METABOLISM; IMMUNOPATHOGENESIS; LIPID METABOLISM; LIPID PEROXIDATION; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METABOLISM; TRANSGENE; UREA NITROGEN BLOOD LEVEL; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; COMPARATIVE STUDY; ENZYMOLOGY; ERYTHROCYTE; GENETICS; HUMAN; MALE; MOUSE MUTANT; PHYSIOLOGY; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

ANEMIA; ANIMALS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; ERYTHROCYTES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 70149087726     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090176     Document Type: Article

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