Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: Clues for understanding the development of Alzheimer disease

Free Radical Biology and Medicine

Volumn 71, Issue , 2014, Pages 270-280

  Di Domenico, Fabio ^a   Pupo, Gilda ^a   Tramutola, Antonella ^a   Giorgi, Alessandra ^a   Schininà, Maria Eugenia ^a   Coccia, Raffaella ^a   Head, Elizabeth ^b   Butterfield, D Allan ^b,c   Perluigi, Marzia ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer disease; Down syndrome; Free radicals; HNE; Lipid peroxidation; Protein oxidation; Redox proteomics; Trisomy 21

Indexed keywords

ALDEHYDE; DNA; LIPID; PROTEIN; 4-HYDROXY-2-NONENAL; NERVE PROTEIN;

ADULT; AGE DISTRIBUTION; AGED; ALZHEIMER DISEASE; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DOWN SYNDROME; ENERGY METABOLISM; FEMALE; FRONTAL CORTEX; HUMAN; LIPID PEROXIDATION; MALE; NERVE DEGENERATION; NEUROPATHOLOGY; OXIDATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEOMICS; QUALITY CONTROL; REDOX PROTEOMICS; SCHOOL CHILD; ADOLESCENT; CHEMISTRY; DISEASE COURSE; FRONTAL LOBE; GENETICS; INFANT; METABOLISM; MIDDLE AGED; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PATHOLOGY; PROTEIN PROCESSING;

ADOLESCENT; ADULT; ALDEHYDES; ALZHEIMER DISEASE; CHILD; DISEASE PROGRESSION; DOWN SYNDROME; FEMALE; FRONTAL LOBE; HUMANS; INFANT; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; PROTEOMICS;

EID: 84898812067     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.03.027     Document Type: Article

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