Nuclear factor erythroid 2-related factor-2 activity controls 4-hydroxynonenal metabolism and activity in prostate cancer cells

Free Radical Biology and Medicine

Volumn 51, Issue 8, 2011, Pages 1610-1618

  Pettazzoni, Piergiorgio ^a,b   Ciamporcero, Eric ^a   Medana, Claudio ^a   Pizzimenti, Stefania ^a   Dal Bello, Federica ^a   Minero, Valerio Giacomo ^a   Toaldo, Cristina ^a   Minelli, Rosalba ^b   Uchida, Koji ^c   Dianzani, Mario Umberto ^a   Pili, Roberto ^b   Barrera, Giuseppina ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

4 Hydroxynonenal; Aldehyde metabolism; Apoptosis; DNA damage; Free radicals; Glutathione; GS HNE adduct; GST A4; KEAP1; Nrf2; Oxidative stress; Prostate cancer

Indexed keywords

4 HYDROXYNONENAL; GLUTATHIONE; GLUTATHIONE TRANSFERASE A4; KELCH LIKE ECH ASSOCIATED PROTEIN 1; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DETOXIFICATION; DNA DAMAGE; DRUG EFFICACY; DRUG METABOLISM; GENE SILENCING; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN CONTENT; PROTEIN EXPRESSION;

ALDEHYDES; APOPTOSIS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL NUCLEUS; DNA DAMAGE; GENE EXPRESSION REGULATION; GLUTATHIONE TRANSFERASE; HUMANS; LIPID PEROXIDATION; MALE; NF-E2-RELATED FACTOR 2; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING;

EID: 80052731775     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.07.009     Document Type: Article

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