Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins

Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2000, Pages 2285-2289

  Lavergne, Olivier ^a   Demarquay, Daniele ^a   Bailly, Christian ^b   Lanco, Christophe ^a   Rolland, Alain ^a   Huchet, Marion ^a   Coulomb, Helène ^a   Muller, Nicole ^a   Baroggi, Nicole ^a   Camara, José ^a   Le Breton, Christine ^c   Manginot, Eric ^c   Cazaux, Jean Bernard ^c   Bigg, Dennis C H ^a  

^a Institut Henri Beaufour   (France)

^b CENTRE OSCAR LAMBRET   (France)

^c Expansia   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN DERIVATIVE; DNA TOPOISOMERASE; FLUORINE;

ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DNA CLEAVAGE; ENANTIOMER; ENZYME ACTIVITY; FLUORINATION; HUMAN; HUMAN CELL; IC 50;

ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; DNA TOPOISOMERASES, TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; HT29 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; STEREOISOMERISM; TUMOR CELLS, CULTURED;

EID: 0034214095     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000129j     Document Type: Article

References (20)

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