Camptothecin, over four decades of surprising findings

Phytochemistry

Volumn 65, Issue 20, 2004, Pages 2735-2749

  Lorence, Argelia ^a   Nessler, Craig L ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Camptotheca acuminata; Camptothecin; Metabolic engineering; Monoterpene indole alkaloids; Ophiorrhiza pumila

Indexed keywords

AMSACRINE; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; CAMPTOTHECIN; DNA TOPOISOMERASE; ETOPOSIDE; FLUOROPYRIMIDINE; FLUOROURACIL; INDOLE ALKALOID; IRINOTECAN; MITOXANTRONE; TOPOTECAN;

ANGIOGENESIS; ANGIOSPERM; ANTINEOPLASTIC ACTIVITY; APOCYNACEAE; APOPTOSIS; BARK; BIOSYNTHESIS; CAMPTOTHECA; CELL KILLING; CELLULAR DISTRIBUTION; CLADISTICS; COLON CANCER; COLORECTAL CANCER; CROSS LINKING; CYTOTOXICITY; DNA DAMAGE; DNA STRAND BREAKAGE; DNA SYNTHESIS; DRUG APPROVAL; DRUG EFFICACY; DRUG MARKETING; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; DRUG SOLUBILITY; DRUG STABILITY; DRUG TOLERABILITY; ESTERIFICATION; GLIOMA; HEMATOLOGIC MALIGNANCY; HUMAN; LEUKEMIA; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MITOSIS INHIBITION; MOLECULAR CLONING; MOLECULAR EVOLUTION; NONHUMAN; NYSSACEAE; OVARY CANCER; PHYLOGENY; PLANT LEAF; REVIEW; RUBIACEAE; STOMACH CANCER; UTERINE CERVIX CANCER;

APOCYNACEAE; CAMPTOTHECA ACUMINATA; ERVATAMIA HEYNEANA; GELSEMIACEAE; ICACINACEAE; MAGNOLIOPHYTA; MERRILLIODENDRON MEGACARPUM; MOSTUEA BRUNONIS; NOTHAPODYTES FOETIDA; NYSSACEAE; OPHIORRHIZA PUMILA; PYRENACANTHA; PYRENACANTHA KLAINEANA; RUBIACEAE;

EID: 4944264246     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2004.09.001     Document Type: Article

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