Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo

Journal of Controlled Release

Volumn 74, Issue 1-3, 2001, Pages 243-247

  Singer, Jack W ^a   Bhatt, Rama ^a   Tulinsky, John ^a   Buhler, Kent R ^a   Heasley, Eveline ^a   Klein, Peter ^a   De Vries, Peter ^a  

^a Cell Therapeutics Inc   (United States)

Author keywords

Camptothecins; Drug delivery; Poly (L glutamic acid); Polymer conjugates

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; GLYCINE; POLYGLUTAMIC ACID; POLYGLUTAMIC ACID GLYCINE CAMPTOTHECIN CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; COLON CANCER; CONFERENCE PAPER; CONTROLLED STUDY; DRUG CONJUGATION; DRUG EFFICACY; DRUG STABILITY; FEMALE; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL CARCINOMA; MAXIMUM TOLERATED DOSE; MELANOMA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; GLYCINE; HT29 CELLS; HUMANS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, NUDE; MOLECULAR WEIGHT; NEOPLASM TRANSPLANTATION; POLYGLUTAMIC ACID; SOLUBILITY;

EID: 0035816202     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(01)00323-6     Document Type: Conference Paper

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