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Volumn 29, Issue 6, 2015, Pages 1233-1242

Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1C; DNA METHYLTRANSFERASE 1; GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; INSULIN RECEPTOR; PROTEIN DLK1; PROTEIN L3MBTL1; PROTEIN MEG3; RETINOBLASTOMA PROTEIN; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; STAT5 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; WT1 PROTEIN;

EID: 84930571431     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2015.47     Document Type: Review
Times cited : (5)

References (141)
  • 1
    • 84904563107 scopus 로고    scopus 로고
    • The role of genomic imprinting in biology and disease: An expanding view
    • Peters J. The role of genomic imprinting in biology and disease: an expanding view. Nat Rev Genet 2014; 15: 517-530.
    • (2014) Nat Rev Genet , vol.15 , pp. 517-530
    • Peters, J.1
  • 5
    • 79952535798 scopus 로고    scopus 로고
    • Genomic imprinting in mammals: Its life cycle, molecular mechanisms and reprogramming
    • Li Y, Sasaki H. Genomic imprinting in mammals: its life cycle, molecular mechanisms and reprogramming. Cell Res 2011; 21: 466-473.
    • (2011) Cell Res , vol.21 , pp. 466-473
    • Li, Y.1    Sasaki, H.2
  • 6
  • 7
    • 84900300766 scopus 로고    scopus 로고
    • Programming and inheritance of parental DNA methylomes in mammals
    • Wang L, Zhang J, Duan J, Gao X, Zhu W, Lu X et al. Programming and inheritance of parental DNA methylomes in mammals. Cell 2014; 157: 979-991.
    • (2014) Cell , vol.157 , pp. 979-991
    • Wang, L.1    Zhang, J.2    Duan, J.3    Gao, X.4    Zhu, W.5    Lu, X.6
  • 8
    • 84899644231 scopus 로고    scopus 로고
    • Genomic imprinting in development, growth, behavior and stem cells
    • Plasschaert RN, Bartolomei MS. Genomic imprinting in development, growth, behavior and stem cells. Development 2014; 141: 1805-1813.
    • (2014) Development , vol.141 , pp. 1805-1813
    • Plasschaert, R.N.1    Bartolomei, M.S.2
  • 9
    • 78650253763 scopus 로고    scopus 로고
    • Genome-wide identification of polycomb-associated RNAs by RIP-seq
    • Zhao J, Ohsumi TK, Kung JT, Ogawa Y, Grau DJ, Sarma K et al. Genome-wide identification of polycomb-associated RNAs by RIP-seq. Mol Cell 2010; 40: 939-953.
    • (2010) Mol Cell , vol.40 , pp. 939-953
    • Zhao, J.1    Ohsumi, T.K.2    Kung, J.T.3    Ogawa, Y.4    Grau, D.J.5    Sarma, K.6
  • 10
    • 84891898005 scopus 로고    scopus 로고
    • Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus
    • Zhang H, Zeitz MJ, Wang H, Niu B, Ge S, Li W et al. Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus. J Cell Biol 2014; 204: 61-75.
    • (2014) J Cell Biol , vol.204 , pp. 61-75
    • Zhang, H.1    Zeitz, M.J.2    Wang, H.3    Niu, B.4    Ge, S.5    Li, W.6
  • 11
    • 84875177348 scopus 로고    scopus 로고
    • X-inactivation imprinting, and long noncoding RNAs in health and disease
    • Lee JT, Bartolomei MS. X-inactivation imprinting, and long noncoding RNAs in health and disease. Cell 2013; 152: 1308-1323.
    • (2013) Cell , vol.152 , pp. 1308-1323
    • Lee, J.T.1    Bartolomei, M.S.2
  • 13
    • 84930576840 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes
    • Boucher J, Charalambous M, Zarse K, Mori MA, Kleinridders A, Ristow M et al. Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes. Proc Natl Acad Sci USA 2014; 111: 14512-14517.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 14512-14517
    • Boucher, J.1    Charalambous, M.2    Zarse, K.3    Mori, M.A.4    Kleinridders, A.5    Ristow, M.6
  • 14
    • 70450260628 scopus 로고    scopus 로고
    • Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells
    • Shin DM, Zuba-Surma EK, Wu W, Ratajczak J, Wysoczynski M, Ratajczak MZ et al. Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct4(+) very small embryonic-like stem cells. Leukemia 2009; 23: 2042-2051.
    • (2009) Leukemia , vol.23 , pp. 2042-2051
    • Shin, D.M.1    Zuba-Surma, E.K.2    Wu, W.3    Ratajczak, J.4    Wysoczynski, M.5    Ratajczak, M.Z.6
  • 15
    • 84895803604 scopus 로고    scopus 로고
    • Very small embryonic-like stem cells (VSELs) represent a real challenge in stem cell biology: Recent pros and cons in the midst of a lively debate
    • Ratajczak MZ, Zuba-Surma E, Wojakowski W, Suszynska M, Mierzejewska K, Liu R et al. Very small embryonic-like stem cells (VSELs) represent a real challenge in stem cell biology: recent pros and cons in the midst of a lively debate. Leukemia 2014; 28: 473-484.
    • (2014) Leukemia , vol.28 , pp. 473-484
    • Ratajczak, M.Z.1    Zuba-Surma, E.2    Wojakowski, W.3    Suszynska, M.4    Mierzejewska, K.5    Liu, R.6
  • 16
    • 78751500429 scopus 로고    scopus 로고
    • Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells
    • Ratajczak J, Wysoczynski M, Zuba-Surma E, Wan W, Kucia M, Yoder MC et al. Adult murine bone marrow-derived very small embryonic-like stem cells differentiate into the hematopoietic lineage after coculture over OP9 stromal cells. Exp Hematol 2011; 39: 225-237.
    • (2011) Exp Hematol , vol.39 , pp. 225-237
    • Ratajczak, J.1    Wysoczynski, M.2    Zuba-Surma, E.3    Wan, W.4    Kucia, M.5    Yoder, M.C.6
  • 17
    • 77955714512 scopus 로고    scopus 로고
    • Molecular signature of adult bone marrow-purified very small embryonic-like stem cells supports their developmental epiblast/germ line origin
    • Shin DM, Liu R, Klich I, Wu W, Ratajczak J, Kucia M et al. Molecular signature of adult bone marrow-purified very small embryonic-like stem cells supports their developmental epiblast/germ line origin. Leukemia 2010; 24: 1450-1461.
    • (2010) Leukemia , vol.24 , pp. 1450-1461
    • Shin, D.M.1    Liu, R.2    Klich, I.3    Wu, W.4    Ratajczak, J.5    Kucia, M.6
  • 18
    • 84886061098 scopus 로고    scopus 로고
    • DNA methylation errors in imprinting disorders and assisted reproductive technology
    • Chiba H, Hiura H, Okae H, Miyauchi N, Sato F, Sato A et al. DNA methylation errors in imprinting disorders and assisted reproductive technology. Pediatr Int 2013; 55: 542-549.
    • (2013) Pediatr Int , vol.55 , pp. 542-549
    • Chiba, H.1    Hiura, H.2    Okae, H.3    Miyauchi, N.4    Sato, F.5    Sato, A.6
  • 19
    • 84925287179 scopus 로고    scopus 로고
    • DLK1-DIO3 imprinted cluster in induced pluripotency: Landscape in the mist
    • Benetatos L, Vartholomatos G, Hatzimichael E. DLK1-DIO3 imprinted cluster in induced pluripotency: landscape in the mist. Cell Mol Life Sci 2014; 71: 4421-4430.
    • (2014) Cell Mol Life Sci , vol.71 , pp. 4421-4430
    • Benetatos, L.1    Vartholomatos, G.2    Hatzimichael, E.3
  • 20
    • 84922637049 scopus 로고    scopus 로고
    • Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors
    • Johannesson B, Sagi I, Gore A, Paull D, Yamada M, Golan-Lev T et al. Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors. Cell Stem Cell 2014; 15: 634-642.
    • (2014) Cell Stem Cell , vol.15 , pp. 634-642
    • Johannesson, B.1    Sagi, I.2    Gore, A.3    Paull, D.4    Yamada, M.5    Golan-Lev, T.6
  • 21
    • 61449215237 scopus 로고    scopus 로고
    • Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: Implications for the evolution of imprinting
    • da Rocha ST, Charalambous M, Lin SP, Gutteridge I, Ito Y, Gray D et al. Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting. PLoS Genet 2009; 5: e1000392.
    • (2009) PLoS Genet , vol.5 , pp. e1000392
    • Da Rocha, S.T.1    Charalambous, M.2    Lin, S.P.3    Gutteridge, I.4    Ito, Y.5    Gray, D.6
  • 24
    • 84878341151 scopus 로고    scopus 로고
    • Dosage-sensitivity of imprinted genes expressed in the brain: 15q11-q13 and neuropsychiatric illness
    • McNamara GI, Isles AR. Dosage-sensitivity of imprinted genes expressed in the brain: 15q11-q13 and neuropsychiatric illness. Biochem Soc Trans 2013; 41: 721-726.
    • (2013) Biochem Soc Trans , vol.41 , pp. 721-726
    • McNamara, G.I.1    Isles, A.R.2
  • 25
    • 79959843335 scopus 로고    scopus 로고
    • Genomic imprinting as an adaptative model of developmental plasticity
    • Radford EJ, Ferrón SR, Ferguson-Smith AC. Genomic imprinting as an adaptative model of developmental plasticity. FEBS Lett 2011; 585: 2059-2066.
    • (2011) FEBS Lett , vol.585 , pp. 2059-2066
    • Radford, E.J.1    Ferrón, S.R.2    Ferguson-Smith, A.C.3
  • 26
    • 33847253548 scopus 로고    scopus 로고
    • A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis
    • Hancock AL, Brown KW, Moorwood K, Moon H, Holmgren C, Mardikar SH et al. A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis. Hum Mol Genet 2007; 16: 343-354.
    • (2007) Hum Mol Genet , vol.16 , pp. 343-354
    • Hancock, A.L.1    Brown, K.W.2    Moorwood, K.3    Moon, H.4    Holmgren, C.5    Mardikar, S.H.6
  • 27
    • 84904244537 scopus 로고    scopus 로고
    • Deregulation of RB expression by loss of imprinting in human hepatocellular carcinoma
    • Anwar SL, Krech T, Hasemeier B, Schipper E, Schweitzer N, Vogel A et al. Deregulation of RB expression by loss of imprinting in human hepatocellular carcinoma. J Pathol 2014; 233: 392-401.
    • (2014) J Pathol , vol.233 , pp. 392-401
    • Anwar, S.L.1    Krech, T.2    Hasemeier, B.3    Schipper, E.4    Schweitzer, N.5    Vogel, A.6
  • 28
    • 84876112831 scopus 로고    scopus 로고
    • Parental imprinting regulates insulin-like growth factor signaling: A Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis
    • Ratajczak MZ, Shin DM, Schneider G, Ratajczak J, Kucia M. Parental imprinting regulates insulin-like growth factor signaling: A Rosetta Stone for understanding the biology of pluripotent stem cells, aging and cancerogenesis. Leukemia 2013; 27: 773-779.
    • (2013) Leukemia , vol.27 , pp. 773-779
    • Ratajczak, M.Z.1    Shin, D.M.2    Schneider, G.3    Ratajczak, J.4    Kucia, M.5
  • 29
    • 84891010570 scopus 로고    scopus 로고
    • Comprehensive analyses of imprinted differentially methylated regions reveal epigenetic and genetic characteristics in hepatoblastoma
    • Rumbajan JM, Maeda T, Souzaki R, Mitsui K, Higashimoto K, Nakabayashi K et al. Comprehensive analyses of imprinted differentially methylated regions reveal epigenetic and genetic characteristics in hepatoblastoma. BMC Cancer 2013; 13: 608.
    • (2013) BMC Cancer , vol.13 , pp. 608
    • Rumbajan, J.M.1    Maeda, T.2    Souzaki, R.3    Mitsui, K.4    Higashimoto, K.5    Nakabayashi, K.6
  • 31
    • 82155186110 scopus 로고    scopus 로고
    • Breast cancer patients with lobular cancer more commonly have a father than a mother diagnosed with cancer
    • Ellberg C, Olsson H. Breast cancer patients with lobular cancer more commonly have a father than a mother diagnosed with cancer. BMC Cancer 2011; 11: 497.
    • (2011) BMC Cancer , vol.11 , pp. 497
    • Ellberg, C.1    Olsson, H.2
  • 33
    • 84905185118 scopus 로고    scopus 로고
    • Developmental hematopoiesis: Ontogeny, genetic programming and conservation
    • Ciau-Uitz A, Monteiro R, Kirmizitas A, Patient R. Developmental hematopoiesis: ontogeny, genetic programming and conservation. Exp Hematol 2014; 42: 669-683.
    • (2014) Exp Hematol , vol.42 , pp. 669-683
    • Ciau-Uitz, A.1    Monteiro, R.2    Kirmizitas, A.3    Patient, R.4
  • 35
    • 84926445768 scopus 로고    scopus 로고
    • A novel view of the adult bone marrow stem cell hierarchy and stem cell trafficking
    • Ratajczak MZ. A novel view of the adult bone marrow stem cell hierarchy and stem cell trafficking. Leukemia 2015; 29: 776-782.
    • (2015) Leukemia , vol.29 , pp. 776-782
    • Ratajczak, M.Z.1
  • 37
    • 84930574986 scopus 로고    scopus 로고
    • Chromatin dynamics during differentiation of myeloid cells
    • 00458-6
    • Schönheit J, Leutz A, Rosenbauer F. Chromatin dynamics during differentiation of myeloid cells. J Mol Biol 2014; pii S0022-2836: 00458-6.
    • (2014) J Mol Biol , vol.P2 , pp. S0022-2836
    • Schönheit, J.1    Leutz, A.2    Rosenbauer, F.3
  • 38
    • 84904043095 scopus 로고    scopus 로고
    • Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle
    • Beerman I, Seita J, Inlay MA, Weissman IL, Rossi DJ. Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle. Cell Stem Cell 2014; 15: 37-50.
    • (2014) Cell Stem Cell , vol.15 , pp. 37-50
    • Beerman, I.1    Seita, J.2    Inlay, M.A.3    Weissman, I.L.4    Rossi, D.J.5
  • 39
    • 84880235551 scopus 로고    scopus 로고
    • Aging of the hematopoietic system
    • Snoeck HW. Aging of the hematopoietic system. Curr Opin Hematol 2013; 20: 355-361.
    • (2013) Curr Opin Hematol , vol.20 , pp. 355-361
    • Snoeck, H.W.1
  • 40
    • 84918509951 scopus 로고    scopus 로고
    • Interferon gamma signaling positively regulates hematopoietic stem cell emergence
    • Sawamiphak S, Kontarakis Z, Stainier DY. Interferon gamma signaling positively regulates hematopoietic stem cell emergence. Dev Cell 2014; 31: 640-653.
    • (2014) Dev Cell , vol.31 , pp. 640-653
    • Sawamiphak, S.1    Kontarakis, Z.2    Stainier, D.Y.3
  • 41
    • 84922541996 scopus 로고    scopus 로고
    • Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis
    • Cabezas-Wallscheid N, Klimmeck D, Hansson J, Lipka DB, Reyes A, Wang Q et al. Identification of regulatory networks in HSCs and their immediate progeny via integrated proteome, transcriptome, and DNA methylome analysis. Cell Stem Cell 2014; 15: 507-522.
    • (2014) Cell Stem Cell , vol.15 , pp. 507-522
    • Cabezas-Wallscheid, N.1    Klimmeck, D.2    Hansson, J.3    Lipka, D.B.4    Reyes, A.5    Wang, Q.6
  • 42
    • 84855264059 scopus 로고    scopus 로고
    • Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1
    • Chau YY, Brownstein D, Mjoseng H, Lee WC, Buza-Vidas N, Nerlov C et al. Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1. PLoS Genet 2011; 7: e1002404.
    • (2011) PLoS Genet , vol.7 , pp. e1002404
    • Chau, Y.Y.1    Brownstein, D.2    Mjoseng, H.3    Lee, W.C.4    Buza-Vidas, N.5    Nerlov, C.6
  • 44
    • 0034329247 scopus 로고    scopus 로고
    • Imprinting of insulin-like growth factor 2 is modulated during hematopoiesis
    • Morison IM, Eccles MR, Reeve AE. Imprinting of insulin-like growth factor 2 is modulated during hematopoiesis. Blood 2000; 96: 3023-3028.
    • (2000) Blood , vol.96 , pp. 3023-3028
    • Morison, I.M.1    Eccles, M.R.2    Reeve, A.E.3
  • 45
    • 80054785092 scopus 로고    scopus 로고
    • Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells
    • Berg JS, Lin KK, Sonnet C, Boles NC, Weksberg DC, Nguyen H et al. Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One 2011; 6: e26410.
    • (2011) PLoS One , vol.6 , pp. e26410
    • Berg, J.S.1    Lin, K.K.2    Sonnet, C.3    Boles, N.C.4    Weksberg, D.C.5    Nguyen, H.6
  • 46
    • 84881668166 scopus 로고    scopus 로고
    • Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence
    • Venkatraman A, He XC, Thorvaldsen JL, Sugimura R, Perry JM, Tao F et al. Maternal imprinting at the H19-Igf2 locus maintains adult haematopoietic stem cell quiescence. Nature 2013; 500: 345-349.
    • (2013) Nature , vol.500 , pp. 345-349
    • Venkatraman, A.1    He, X.C.2    Thorvaldsen, J.L.3    Sugimura, R.4    Perry, J.M.5    Tao, F.6
  • 47
    • 84881127297 scopus 로고    scopus 로고
    • Parental permissions: H19 and keeping the stem cell progeny under control
    • Goodell MA. Parental permissions: H19 and keeping the stem cell progeny under control. Cell Stem Cell 2013; 13: 137-138.
    • (2013) Cell Stem Cell , vol.13 , pp. 137-138
    • Goodell, M.A.1
  • 48
    • 33750470266 scopus 로고    scopus 로고
    • Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth
    • Varrault A, Gueydan C, Delalbre A, Bellmann A, Houssami S, Aknin C et al. Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth. Dev Cell 2006; 11: 711-722.
    • (2006) Dev Cell , vol.11 , pp. 711-722
    • Varrault, A.1    Gueydan, C.2    Delalbre, A.3    Bellmann, A.4    Houssami, S.5    Aknin, C.6
  • 49
    • 44649089286 scopus 로고    scopus 로고
    • The role of parathyroid hormone and insulin-like growth factors in hematopoietic niches: Physiology and pharmacology
    • Garrett RW, Emerson SG. The role of parathyroid hormone and insulin-like growth factors in hematopoietic niches: physiology and pharmacology. Mol Cell Endocrinol 2008; 288: 6-10.
    • (2008) Mol Cell Endocrinol , vol.288 , pp. 6-10
    • Garrett, R.W.1    Emerson, S.G.2
  • 50
    • 1642371165 scopus 로고    scopus 로고
    • Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells
    • Zhang CC, Lodish HF. Insulin-like growth factor 2 expressed in a novel fetal liver cell population is a growth factor for hematopoietic stem cells. Blood 2004; 103: 2513-2521.
    • (2004) Blood , vol.103 , pp. 2513-2521
    • Zhang, C.C.1    Lodish, H.F.2
  • 51
    • 46349084823 scopus 로고    scopus 로고
    • Synergistic role of Igf2 and Dlk1 in fetal liver development and hematopoiesis in bi-maternal mice
    • Wu Q, Kawahara M, Kono T. Synergistic role of Igf2 and Dlk1 in fetal liver development and hematopoiesis in bi-maternal mice. J Reprod Dev 2008; 54: 177-182.
    • (2008) J Reprod Dev , vol.54 , pp. 177-182
    • Wu, Q.1    Kawahara, M.2    Kono, T.3
  • 52
    • 84922656553 scopus 로고    scopus 로고
    • Delta-like homologue 1 and its role in the bone marrow niche and hematologic malignancies
    • Benetatos L, Hatzimichael E. Delta-like homologue 1 and its role in the bone marrow niche and hematologic malignancies. Clin Lymphoma Myeloma Leuk 2014; 14: 451-455.
    • (2014) Clin Lymphoma Myeloma Leuk , vol.14 , pp. 451-455
    • Benetatos, L.1    Hatzimichael, E.2
  • 53
    • 84922539408 scopus 로고    scopus 로고
    • Transcriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitment
    • Klimmeck D, Cabezas-Wallscheid N, Reyes A, von Paleske L, Renders S, Hansson J et al. Transcriptome-wide profiling and posttranscriptional analysis of hematopoietic stem/progenitor cell differentiation toward myeloid commitment. Stem Cell Rep 2014; 3: 858-875.
    • (2014) Stem Cell Rep , vol.3 , pp. 858-875
    • Klimmeck, D.1    Cabezas-Wallscheid, N.2    Reyes, A.3    Von Paleske, L.4    Renders, S.5    Hansson, J.6
  • 54
    • 84899768899 scopus 로고    scopus 로고
    • Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal
    • Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R et al. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell 2014; 14: 673-688.
    • (2014) Cell Stem Cell , vol.14 , pp. 673-688
    • Sun, D.1    Luo, M.2    Jeong, M.3    Rodriguez, B.4    Xia, Z.5    Hannah, R.6
  • 55
    • 80052281899 scopus 로고    scopus 로고
    • P57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70
    • Zou P, Yoshihara H, Hosokawa K, Tai I, Shinmyozu K, Tsukahara F et al. p57(Kip2) and p27(Kip1) cooperate to maintain hematopoietic stem cell quiescence through interactions with Hsc70. Cell Stem Cell 2011; 9: 247-261.
    • (2011) Cell Stem Cell , vol.9 , pp. 247-261
    • Zou, P.1    Yoshihara, H.2    Hosokawa, K.3    Tai, I.4    Shinmyozu, K.5    Tsukahara, F.6
  • 56
    • 84866129506 scopus 로고    scopus 로고
    • Less is more: Unveiling the functional core of hematopoietic stem cells through knockout mice
    • Rossi L, Lin KK, Boles NC, Yang L, King KY, Jeong M et al. Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell 2012; 11: 302-317.
    • (2012) Cell Stem Cell , vol.11 , pp. 302-317
    • Rossi, L.1    Lin, K.K.2    Boles, N.C.3    Yang, L.4    King, K.Y.5    Jeong, M.6
  • 59
    • 84884969443 scopus 로고    scopus 로고
    • DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation
    • Das R, Lee YK, Strogantsev R, Jin S, Lim YC, Ng PY et al. DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation. BMC Genomics 2013; 14: 685.
    • (2013) BMC Genomics , vol.14 , pp. 685
    • Das, R.1    Lee, Y.K.2    Strogantsev, R.3    Jin, S.4    Lim, Y.C.5    Ng, P.Y.6
  • 61
    • 70349469788 scopus 로고    scopus 로고
    • DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
    • Trowbridge JJ, Snow JW, Kim J, Orkin SH. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 2009; 5: 442-449.
    • (2009) Cell Stem Cell , vol.5 , pp. 442-449
    • Trowbridge, J.J.1    Snow, J.W.2    Kim, J.3    Orkin, S.H.4
  • 63
    • 84920973388 scopus 로고    scopus 로고
    • Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation
    • Reinisch A, Etchart N, Thomas D, Hofmann NA, Fruehwirth M, Sinha S et al. Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation. Blood 2014; 125: 249-260.
    • (2014) Blood , vol.125 , pp. 249-260
    • Reinisch, A.1    Etchart, N.2    Thomas, D.3    Hofmann, N.A.4    Fruehwirth, M.5    Sinha, S.6
  • 64
    • 84923776535 scopus 로고    scopus 로고
    • RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells
    • Lin SP, Chiu FY, Wang Y, Yen ML, Kao SY, Hung SC. RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells. Stem Cell Rep 2014; 3: 975-986.
    • (2014) Stem Cell Rep , vol.3 , pp. 975-986
    • Lin, S.P.1    Chiu, F.Y.2    Wang, Y.3    Yen, M.L.4    Kao, S.Y.5    Hung, S.C.6
  • 66
    • 84882412558 scopus 로고    scopus 로고
    • Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation
    • Miraki-Moud F, Anjos-Afonso F, Hodby KA, Griessinger E, Rosignoli G, Lillington D et al. Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation. Proc Natl Acad Sci USA 2013; 110: 13576-13581.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 13576-13581
    • Miraki-Moud, F.1    Anjos-Afonso, F.2    Hodby, K.A.3    Griessinger, E.4    Rosignoli, G.5    Lillington, D.6
  • 67
    • 84908112555 scopus 로고    scopus 로고
    • Concise reviews: Cancer stem cells: From concept to cure
    • Matchett KB, Lappin TR. Concise reviews: cancer stem cells: from concept to cure. Stem Cells 2014; 32: 2563-2570.
    • (2014) Stem Cells , vol.32 , pp. 2563-2570
    • Matchett, K.B.1    Lappin, T.R.2
  • 69
    • 78651416188 scopus 로고    scopus 로고
    • Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia
    • Goardon N, Marchi E, Atzberger A, Quek L, Schuh A, Soneji S et al. Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia. Cancer Cell 2011; 19: 138-152.
    • (2011) Cancer Cell , vol.19 , pp. 138-152
    • Goardon, N.1    Marchi, E.2    Atzberger, A.3    Quek, L.4    Schuh, A.5    Soneji, S.6
  • 70
    • 0031566230 scopus 로고    scopus 로고
    • Loss of imprinting of human insulinlike growth factor II gene, IGF2, in acute myeloid leukemia
    • Wu HK, Weksberg R, Minden MD, Squire JA. Loss of imprinting of human insulinlike growth factor II gene, IGF2, in acute myeloid leukemia. Biochem Biophys Res Commun 1997; 231: 466-472.
    • (1997) Biochem Biophys Res Commun , vol.231 , pp. 466-472
    • Wu, H.K.1    Weksberg, R.2    Minden, M.D.3    Squire, J.A.4
  • 71
    • 0036215814 scopus 로고    scopus 로고
    • Loss of genomic imprinting of insulin-like growth factor 2 is strongly associated with cellular proliferation in normal hematopoietic cells
    • Hofmann WK, Takeuchi S, Frantzen MA, Hoelzer D, Koeffler HP. Loss of genomic imprinting of insulin-like growth factor 2 is strongly associated with cellular proliferation in normal hematopoietic cells. Exp Hematol 2002; 30: 318-323.
    • (2002) Exp Hematol , vol.30 , pp. 318-323
    • Hofmann, W.K.1    Takeuchi, S.2    Frantzen, M.A.3    Hoelzer, D.4    Koeffler, H.P.5
  • 72
    • 0037396541 scopus 로고    scopus 로고
    • Reduced expression of H19 in bone marrow cells from chronic myeloproliferative disorders
    • Bock O, Schlué J, Kreipe H. Reduced expression of H19 in bone marrow cells from chronic myeloproliferative disorders. Leukemia 2003; 17: 815-816.
    • (2003) Leukemia , vol.17 , pp. 815-816
    • Bock, O.1    Schlué, J.2    Kreipe, H.3
  • 73
    • 0033485290 scopus 로고    scopus 로고
    • The insulin-like growth factor system in normal and malignant hematopoietic cells
    • Zumkeller W, Burdach S. The insulin-like growth factor system in normal and malignant hematopoietic cells. Blood 1999; 94: 3653-3657.
    • (1999) Blood , vol.94 , pp. 3653-3657
    • Zumkeller, W.1    Burdach, S.2
  • 74
    • 0342979785 scopus 로고    scopus 로고
    • Expression of the imprinted tumour-suppressor gene H19 is tightly regulated during normal haematopoiesis and is reduced in haematopoietic precursors of patients with the myeloproliferative disease polycythaemia vera
    • Núnez C, Bashein AM, Brunet CL, Hoyland JA, Freemont AJ, Buckle AM et al. Expression of the imprinted tumour-suppressor gene H19 is tightly regulated during normal haematopoiesis and is reduced in haematopoietic precursors of patients with the myeloproliferative disease polycythaemia vera. J Pathol 2000; 190: 61-68.
    • (2000) J Pathol , vol.190 , pp. 61-68
    • Núnez, C.1    Bashein, A.M.2    Brunet, C.L.3    Hoyland, J.A.4    Freemont, A.J.5    Buckle, A.M.6
  • 76
    • 84899649692 scopus 로고    scopus 로고
    • High expression of long non-coding RNA H19 is required for efficient tumorigenesis induced by Bcr-Abl oncogene
    • Guo G, Kang Q, Chen Q, Chen Z, Wang J, Tan L et al. High expression of long non-coding RNA H19 is required for efficient tumorigenesis induced by Bcr-Abl oncogene. FEBS Lett 2014; 588: 1780-1786.
    • (2014) FEBS Lett , vol.588 , pp. 1780-1786
    • Guo, G.1    Kang, Q.2    Chen, Q.3    Chen, Z.4    Wang, J.5    Tan, L.6
  • 78
    • 33845982875 scopus 로고    scopus 로고
    • Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1)
    • Guglielmelli P, Zini R, Bogani C, Salati S, Pancrazzi A, Bianchi E et al. Molecular profiling of CD34+ cells in idiopathic myelofibrosis identifies a set of disease-associated genes and reveals the clinical significance of Wilms' tumor gene 1 (WT1). Stem Cells 2007; 25: 165-173.
    • (2007) Stem Cells , vol.25 , pp. 165-173
    • Guglielmelli, P.1    Zini, R.2    Bogani, C.3    Salati, S.4    Pancrazzi, A.5    Bianchi, E.6
  • 79
    • 84878290096 scopus 로고    scopus 로고
    • Effect of DLK1 on tumorigenesis in CD34+CD38-bone marrow cells in myelodysplastic syndromes
    • Zhang W, Shao Z, Fu R, Wang H, Li L, Yue L. Effect of DLK1 on tumorigenesis in CD34+CD38-bone marrow cells in myelodysplastic syndromes. Oncol Lett 2013; 6: 203-206.
    • (2013) Oncol Lett , vol.6 , pp. 203-206
    • Zhang, W.1    Shao, Z.2    Fu, R.3    Wang, H.4    Li, L.5    Yue, L.6
  • 80
    • 21744438770 scopus 로고    scopus 로고
    • Expression of DLK1 in hematopoietic cells results in inhibition of differentiation and proliferation
    • Li L, Forman SJ, Bhatia R. Expression of DLK1 in hematopoietic cells results in inhibition of differentiation and proliferation. Oncogene 2005; 24: 4472-4476.
    • (2005) Oncogene , vol.24 , pp. 4472-4476
    • Li, L.1    Forman, S.J.2    Bhatia, R.3
  • 81
    • 77957997617 scopus 로고    scopus 로고
    • Meis1 disrupts the genomic imprint of Dlk1 in a NUP98-HOXD13 leukemia model
    • Argiropoulos B, Palmqvist L, Imren S, Miller M, Rouhi A, Mager DL et al. Meis1 disrupts the genomic imprint of Dlk1 in a NUP98-HOXD13 leukemia model. Leukemia 2010; 24: 1788-1791.
    • (2010) Leukemia , vol.24 , pp. 1788-1791
    • Argiropoulos, B.1    Palmqvist, L.2    Imren, S.3    Miller, M.4    Rouhi, A.5    Mager, D.L.6
  • 82
    • 74849131060 scopus 로고    scopus 로고
    • CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes
    • Benetatos L, Hatzimichael E, Dasoula A, Dranitsaris G, Tsiara S, Syrrou M et al. CpG methylation analysis of the MEG3 and SNRPN imprinted genes in acute myeloid leukemia and myelodysplastic syndromes. Leuk Res 2010; 34: 148-153.
    • (2010) Leuk Res , vol.34 , pp. 148-153
    • Benetatos, L.1    Hatzimichael, E.2    Dasoula, A.3    Dranitsaris, G.4    Tsiara, S.5    Syrrou, M.6
  • 83
    • 77950430320 scopus 로고    scopus 로고
    • An upstream insulator regulates DLK1 imprinting in AML
    • Khoury H, Suarez-Saiz F, Wu S, Minden MD. An upstream insulator regulates DLK1 imprinting in AML. Blood 2010; 115: 2260-2263.
    • (2010) Blood , vol.115 , pp. 2260-2263
    • Khoury, H.1    Suarez-Saiz, F.2    Wu, S.3    Minden, M.D.4
  • 84
    • 84897512906 scopus 로고    scopus 로고
    • Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia
    • Manodoro F, Marzec J, Chaplin T, Miraki-Moud F, Moravcsik E, Jovanovic JV et al. Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia. Blood 2014; 123: 2066-2074.
    • (2014) Blood , vol.123 , pp. 2066-2074
    • Manodoro, F.1    Marzec, J.2    Chaplin, T.3    Miraki-Moud, F.4    Moravcsik, E.5    Jovanovic, J.V.6
  • 85
    • 84923887243 scopus 로고    scopus 로고
    • Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34 + cells from patients with primary myelofibrosis and their clinical correlations
    • Pennucci V, Zini R, Norfo R, Guglielmelli P, Bianchi E, Salati S et al. Abnormal expression patterns of WT1-as, MEG3 and ANRIL long non-coding RNAs in CD34 + cells from patients with primary myelofibrosis and their clinical correlations. Leuk Lymphoma 2014; 56: 492-496.
    • (2014) Leuk Lymphoma , vol.56 , pp. 492-496
    • Pennucci, V.1    Zini, R.2    Norfo, R.3    Guglielmelli, P.4    Bianchi, E.5    Salati, S.6
  • 87
    • 84877622988 scopus 로고    scopus 로고
    • Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells
    • Kustikova OS, Schwarzer A, Stahlhut M, Brugman MH, Neumann T, Yang M et al. Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells. Leukemia 2013; 27: 1127-1138.
    • (2013) Leukemia , vol.27 , pp. 1127-1138
    • Kustikova, O.S.1    Schwarzer, A.2    Stahlhut, M.3    Brugman, M.H.4    Neumann, T.5    Yang, M.6
  • 88
    • 80053653651 scopus 로고    scopus 로고
    • PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function
    • Zhang Y, Stehling-Sun S, Lezon-Geyda K, Juneja SC, Coillard L, Chatterjee G et al. PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function. Blood 2011; 118: 3853-3861.
    • (2011) Blood , vol.118 , pp. 3853-3861
    • Zhang, Y.1    Stehling-Sun, S.2    Lezon-Geyda, K.3    Juneja, S.C.4    Coillard, L.5    Chatterjee, G.6
  • 89
    • 6344293545 scopus 로고    scopus 로고
    • Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation
    • Scandura JM, Boccuni P, Massagué J, Nimer SD. Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation. Proc Natl Acad Sci USA 2004; 101: 15231-15236.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15231-15236
    • Scandura, J.M.1    Boccuni, P.2    Massagué, J.3    Nimer, S.D.4
  • 90
    • 42249091050 scopus 로고    scopus 로고
    • The absence of CDKN1C (p57KIP2) promoter methylation in myeloid malignancies also characterizes plasma cell neoplasms
    • Hatzimichael E, Dasoula A, Benetatos L, Makis A, Stebbing J, Crook T et al. The absence of CDKN1C (p57KIP2) promoter methylation in myeloid malignancies also characterizes plasma cell neoplasms. Br J Haematol 2008; 141: 557-558.
    • (2008) Br J Haematol , vol.141 , pp. 557-558
    • Hatzimichael, E.1    Dasoula, A.2    Benetatos, L.3    Makis, A.4    Stebbing, J.5    Crook, T.6
  • 91
    • 24744470483 scopus 로고    scopus 로고
    • Absence of p21(CIP 1), p27(KIP 1) and p 57(KIP 2) methylation in MDS and AML
    • Brakensiek K, Länger F, Kreipe H, Lehmann U. Absence of p21(CIP 1), p27(KIP 1) and p 57(KIP 2) methylation in MDS and AML. Leuk Res 2005; 29: 1357-1360.
    • (2005) Leuk Res , vol.29 , pp. 1357-1360
    • Brakensiek, K.1    Länger, F.2    Kreipe, H.3    Lehmann, U.4
  • 92
    • 0036785401 scopus 로고    scopus 로고
    • Aberrant DNA methylation of p57(KIP2) gene in the promoter region in lymphoid malignancies of B-cell phenotype
    • Li Y, Nagai H, Ohno T, Yuge M, Hatano S, Ito E et al. Aberrant DNA methylation of p57(KIP2) gene in the promoter region in lymphoid malignancies of B-cell phenotype. Blood 2002; 100: 2572-2577.
    • (2002) Blood , vol.100 , pp. 2572-2577
    • Li, Y.1    Nagai, H.2    Ohno, T.3    Yuge, M.4    Hatano, S.5    Ito, E.6
  • 93
    • 79952202038 scopus 로고    scopus 로고
    • P57Kip2 is a downstream effector of BCR-ABL kinase inhibitors in chronic myelogenous leukemia cells
    • Borriello A, Caldarelli I, Bencivenga D, Cucciolla V, Oliva A, Usala E et al. p57Kip2 is a downstream effector of BCR-ABL kinase inhibitors in chronic myelogenous leukemia cells. Carcinogenesis 2011; 32: 10-18.
    • (2011) Carcinogenesis , vol.32 , pp. 10-18
    • Borriello, A.1    Caldarelli, I.2    Bencivenga, D.3    Cucciolla, V.4    Oliva, A.5    Usala, E.6
  • 94
    • 2442544539 scopus 로고    scopus 로고
    • Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies
    • Li J, Bench AJ, Vassiliou GS, Fourouclas N, Ferguson-Smith AC, Green AR. Imprinting of the human L3MBTL gene, a polycomb family member located in a region of chromosome 20 deleted in human myeloid malignancies. Proc Natl Acad Sci USA 2004; 101: 7341-7346.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7341-7346
    • Li, J.1    Bench, A.J.2    Vassiliou, G.S.3    Fourouclas, N.4    Ferguson-Smith, A.C.5    Green, A.R.6
  • 95
    • 78651107405 scopus 로고    scopus 로고
    • L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability
    • Gurvich N, Perna F, Farina A, Voza F, Menendez S, Hurwitz J et al. L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability. Proc Natl Acad Sci USA 2010; 107: 22552-22557.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 22552-22557
    • Gurvich, N.1    Perna, F.2    Farina, A.3    Voza, F.4    Menendez, S.5    Hurwitz, J.6
  • 96
    • 10344262019 scopus 로고    scopus 로고
    • Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignancies
    • Bench AJ, Li J, Huntly BJ, Delabesse E, Fourouclas N, Hunt AR et al. Characterization of the imprinted polycomb gene L3MBTL, a candidate 20q tumour suppressor gene, in patients with myeloid malignancies. Br J Haematol 2004; 127: 509-518.
    • (2004) Br J Haematol , vol.127 , pp. 509-518
    • Bench, A.J.1    Li, J.2    Huntly, B.J.3    Delabesse, E.4    Fourouclas, N.5    Hunt, A.R.6
  • 97
    • 77957945719 scopus 로고    scopus 로고
    • Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: Possible role in 20q-polycythemia vera
    • Perna F, Gurvich N, Hoya-Arias R, Abdel-Wahab O, Levine RL, Asai T et al. Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q-polycythemia vera. Blood 2010; 116: 2812-2821.
    • (2010) Blood , vol.116 , pp. 2812-2821
    • Perna, F.1    Gurvich, N.2    Hoya-Arias, R.3    Abdel-Wahab, O.4    Levine, R.L.5    Asai, T.6
  • 98
    • 84877153495 scopus 로고    scopus 로고
    • Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions
    • Aziz A, Baxter EJ, Edwards C, Cheong CY, Ito M, Bench A et al. Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions. J Clin Invest 2013; 123: 2169-2182.
    • (2013) J Clin Invest , vol.123 , pp. 2169-2182
    • Aziz, A.1    Baxter, E.J.2    Edwards, C.3    Cheong, C.Y.4    Ito, M.5    Bench, A.6
  • 99
    • 34247579714 scopus 로고    scopus 로고
    • A tumor suppressor and oncogene: The WT1 story
    • Yang L, Han Y, Suarez Saiz F, Minden MD. A tumor suppressor and oncogene: the WT1 story. Leukemia 2007; 21: 868-876.
    • (2007) Leukemia , vol.21 , pp. 868-876
    • Yang, L.1    Han, Y.2    Suarez Saiz, F.3    Minden, M.D.4
  • 100
    • 0038780854 scopus 로고    scopus 로고
    • WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: Therapeutic potential of WT1 targeted therapies
    • Rosenfeld C, Cheever MA, Gaiger A. WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies. Leukemia 2003; 17: 1301-1312.
    • (2003) Leukemia , vol.17 , pp. 1301-1312
    • Rosenfeld, C.1    Cheever, M.A.2    Gaiger, A.3
  • 101
    • 51649098597 scopus 로고    scopus 로고
    • Frequency and timing of loss of imprinting at 11p13 and 11p15 in Wilms' tumor development
    • Brown KW, Power F, Moore B, Charles AK, Malik KT. Frequency and timing of loss of imprinting at 11p13 and 11p15 in Wilms' tumor development. Mol Cancer Res 2008; 6: 1114-1123.
    • (2008) Mol Cancer Res , vol.6 , pp. 1114-1123
    • Brown, K.W.1    Power, F.2    Moore, B.3    Charles, A.K.4    Malik, K.T.5
  • 102
    • 84893386005 scopus 로고    scopus 로고
    • Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels
    • Guillaumet-Adkins A, Richter J, Odero MD, Sandoval J, Agirre X, Catala A et al. Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels. J. Hematol Oncol 2014; 7: 4.
    • (2014) J. Hematol Oncol , vol.7 , pp. 4
    • Guillaumet-Adkins, A.1    Richter, J.2    Odero, M.D.3    Sandoval, J.4    Agirre, X.5    Catala, A.6
  • 103
    • 84912531145 scopus 로고    scopus 로고
    • Wilms' tumor gene 1 transcript levels in leukapheresis of peripheral blood hematopoietic cells predict relapse risk in patients autografted for acute myeloid leukemia
    • Messina C, Candoni A, Carrabba MG, Tresoldi C, Sala E, Tassara M et al. Wilms' tumor gene 1 transcript levels in leukapheresis of peripheral blood hematopoietic cells predict relapse risk in patients autografted for acute myeloid leukemia. Biol Blood Marrow Transplant 2014; 20: 1586-1591.
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. 1586-1591
    • Messina, C.1    Candoni, A.2    Carrabba, M.G.3    Tresoldi, C.4    Sala, E.5    Tassara, M.6
  • 104
    • 84888219405 scopus 로고    scopus 로고
    • Clinical and biological implications of driver mutations in myelodysplastic syndromes
    • Papaemmanuil E, Gerstung M, Malcovati L, Tauro S, Gundem G, Van Loo P et al. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood 2013; 122: 3616-3627.
    • (2013) Blood , vol.122 , pp. 3616-3627
    • Papaemmanuil, E.1    Gerstung, M.2    Malcovati, L.3    Tauro, S.4    Gundem, G.5    Van Loo, P.6
  • 105
    • 84907346397 scopus 로고    scopus 로고
    • Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia
    • Malcovati L, Papaemmanuil E, Ambaglio I, Elena C, Gallì A, Della Porta MG et al. Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia. Blood 2014; 124: 1513-1521.
    • (2014) Blood , vol.124 , pp. 1513-1521
    • Malcovati, L.1    Papaemmanuil, E.2    Ambaglio, I.3    Elena, C.4    Gallì, A.5    Della Porta, M.G.6
  • 106
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications
    • Marcucci G, Haferlach T, Döhner H. Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications. J Clin Oncol 2011; 29: 475-486.
    • (2011) J Clin Oncol , vol.29 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Döhner, H.3
  • 107
    • 66549116716 scopus 로고    scopus 로고
    • Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: A study of the German-Austrian AML Study Group
    • Gaidzik VI, Schlenk RF, Moschny S, Becker A, Bullinger L, Corbacioglu A et al. Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: A study of the German-Austrian AML Study Group. Blood 2009; 113: 4505-4511.
    • (2009) Blood , vol.113 , pp. 4505-4511
    • Gaidzik, V.I.1    Schlenk, R.F.2    Moschny, S.3    Becker, A.4    Bullinger, L.5    Corbacioglu, A.6
  • 108
    • 34447634119 scopus 로고    scopus 로고
    • The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis
    • Hosen N, Shirakata T, Nishida S, Yanagihara M, Tsuboi A, Kawakami M et al. The Wilms' tumor gene WT1-GFP knock-in mouse reveals the dynamic regulation of WT1 expression in normal and leukemic hematopoiesis. Leukemia 2007; 21: 1783-1791.
    • (2007) Leukemia , vol.21 , pp. 1783-1791
    • Hosen, N.1    Shirakata, T.2    Nishida, S.3    Yanagihara, M.4    Tsuboi, A.5    Kawakami, M.6
  • 109
    • 33645729159 scopus 로고    scopus 로고
    • AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1
    • Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M et al. AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1. Blood 2006; 107: 3303-3312.
    • (2006) Blood , vol.107 , pp. 3303-3312
    • Nishida, S.1    Hosen, N.2    Shirakata, T.3    Kanato, K.4    Yanagihara, M.5
  • 110
    • 77956294488 scopus 로고    scopus 로고
    • Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
    • Becker H, Marcucci G, Maharry K, Radmacher MD, Mrózek K, Margeson D et al. Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study. Blood 2010; 116: 788-792.
    • (2010) Blood , vol.116 , pp. 788-792
    • Becker, H.1    Marcucci, G.2    Maharry, K.3    Radmacher, M.D.4    Mrózek, K.5    Margeson, D.6
  • 111
    • 78649461721 scopus 로고    scopus 로고
    • Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias
    • Bansal H, Bansal S, Rao M, Foley KP, Sang J, Proia DA et al. Heat shock protein 90 regulates the expression of Wilms tumor 1 protein in myeloid leukemias. Blood 2010; 116: 4591-4599.
    • (2010) Blood , vol.116 , pp. 4591-4599
    • Bansal, H.1    Bansal, S.2    Rao, M.3    Foley, K.P.4    Sang, J.5    Proia, D.A.6
  • 112
    • 84920994589 scopus 로고    scopus 로고
    • Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition
    • Sinha S, Thomas D, Yu L, Gentles A, Jung N, Corces-Zimmerman MR et al. Mutant WT1 is associated with DNA hypermethylation of PRC2 targets in AML and responds to EZH2 inhibition. Blood 2014; 125: 316-326.
    • (2014) Blood , vol.125 , pp. 316-326
    • Sinha, S.1    Thomas, D.2    Yu, L.3    Gentles, A.4    Jung, N.5    Corces-Zimmerman, M.R.6
  • 113
    • 84915789576 scopus 로고    scopus 로고
    • DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of tet2 function in acute myeloid leukemia
    • Rampal R, Alkalin A, Madzo J, Vasanthakumar A, Pronier E, Patel J et al. DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia. Cell Rep 2014; 9: 1841-1855.
    • (2014) Cell Rep , vol.9 , pp. 1841-1855
    • Rampal, R.1    Alkalin, A.2    Madzo, J.3    Vasanthakumar, A.4    Pronier, E.5    Patel, J.6
  • 114
    • 84923847396 scopus 로고    scopus 로고
    • WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation
    • 01001-01006
    • Wang Y, Xiao M, Chen X, Chen L, Xu Y, Lv L et al. WT1 Recruits TET2 to Regulate Its Target Gene Expression and Suppress Leukemia Cell Proliferation. Mol Cell 2015; pii S1097-2765: 01001-01006.
    • (2015) Mol Cell , vol.P2 , pp. S1097-2765
    • Wang, Y.1    Xiao, M.2    Chen, X.3    Chen, L.4    Xu, Y.5    Lv, L.6
  • 115
    • 70350654370 scopus 로고    scopus 로고
    • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
    • Bröske AM, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet 2009; 41: 1207-1215.
    • (2009) Nat Genet , vol.41 , pp. 1207-1215
    • Bröske, A.M.1    Vockentanz, L.2    Kharazi, S.3    Huska, M.R.4    Mancini, E.5    Scheller, M.6
  • 116
    • 67650588646 scopus 로고    scopus 로고
    • MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
    • Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 2009; 113: 6411-6418.
    • (2009) Blood , vol.113 , pp. 6411-6418
    • Garzon, R.1    Liu, S.2    Fabbri, M.3    Liu, Z.4    Heaphy, C.E.5    Callegari, E.6
  • 119
    • 84863176405 scopus 로고    scopus 로고
    • Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains
    • Trowbridge JJ, Sinha AU, Zhu N, Li M, Armstrong SA, Orkin SH. Haploinsufficiency of Dnmt1 impairs leukemia stem cell function through derepression of bivalent chromatin domains. Genes Dev 2012; 26: 344-349.
    • (2012) Genes Dev , vol.26 , pp. 344-349
    • Trowbridge, J.J.1    Sinha, A.U.2    Zhu, N.3    Li, M.4    Armstrong, S.A.5    Orkin, S.H.6
  • 120
    • 0033917545 scopus 로고    scopus 로고
    • Relative locations of the centromere and imprinted SNRPN gene within chromosome 15 territories during the cell cycle in HL60 cells
    • Nogami M, Kohda A, Taguchi H, Nakao M, Ikemura T, Okumura K. Relative locations of the centromere and imprinted SNRPN gene within chromosome 15 territories during the cell cycle in HL60 cells. J Cell Sci 2000; 113(Pt 12): 2157-2165.
    • (2000) J Cell Sci , vol.113 , pp. 2157-2165
    • Nogami, M.1    Kohda, A.2    Taguchi, H.3    Nakao, M.4    Ikemura, T.5    Okumura, K.6
  • 121
    • 84930003179 scopus 로고    scopus 로고
    • Age-related mutations associated with clonal hematopoietic expansion and malignancies
    • Xie M, Lu C, Wang J, McLellan MD, Johnson KJ, Wendl MC et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med 2014; 20: 1472-1478.
    • (2014) Nat Med , vol.20 , pp. 1472-1478
    • Xie, M.1    Lu, C.2    Wang, J.3    McLellan, M.D.4    Johnson, K.J.5    Wendl, M.C.6
  • 122
    • 84893772765 scopus 로고    scopus 로고
    • Landscape of genetic lesions in patients with myelodysplastic syndromes
    • Haferlach T, Nagata Y, Grossmann V, Okuno Y, Bacher U, Nagae G et al. Landscape of genetic lesions in patients with myelodysplastic syndromes. Leukemia 2014; 28: 241-247.
    • (2014) Leukemia , vol.28 , pp. 241-247
    • Haferlach, T.1    Nagata, Y.2    Grossmann, V.3    Okuno, Y.4    Bacher, U.5    Nagae, G.6
  • 124
    • 84925451545 scopus 로고    scopus 로고
    • A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies
    • Sun J, Li W, Sun Y, Yu D, Wen X, Wang H et al. A novel antisense long noncoding RNA within the IGF1R gene locus is imprinted in hematopoietic malignancies. Nucleic Acids Res 2014; 42: 9588-9601.
    • (2014) Nucleic Acids Res , vol.42 , pp. 9588-9601
    • Sun, J.1    Li, W.2    Sun, Y.3    Yu, D.4    Wen, X.5    Wang, H.6
  • 125
    • 0036253182 scopus 로고    scopus 로고
    • Hypermethylation of the imprinted NNAT locus occurs frequently in pediatric acute leukemia
    • Kuerbitz SJ, Pahys J, Wilson A, Compitello N, Gray TA. Hypermethylation of the imprinted NNAT locus occurs frequently in pediatric acute leukemia. Carcinogenesis 2002; 23: 559-564.
    • (2002) Carcinogenesis , vol.23 , pp. 559-564
    • Kuerbitz, S.J.1    Pahys, J.2    Wilson, A.3    Compitello, N.4    Gray, T.A.5
  • 126
    • 84855282492 scopus 로고    scopus 로고
    • Epigenetic regulation by RAR? Maintains ligand-independent transcriptional activity
    • Laursen KB, Wong PM, Gudas LJ. Epigenetic regulation by RAR? maintains ligand-independent transcriptional activity. Nucleic Acids Res 2012; 40: 102-115.
    • (2012) Nucleic Acids Res , vol.40 , pp. 102-115
    • Laursen, K.B.1    Wong, P.M.2    Gudas, L.J.3
  • 127
    • 78650444882 scopus 로고    scopus 로고
    • Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia
    • Gentles AJ, Plevritis SK, Majeti R, Alizadeh AA. Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia. JAMA 2010; 304: 2706-2715.
    • (2010) JAMA , vol.304 , pp. 2706-2715
    • Gentles, A.J.1    Plevritis, S.K.2    Majeti, R.3    Alizadeh, A.A.4
  • 128
    • 84863910743 scopus 로고    scopus 로고
    • Recent advances in acute myeloid leukemia stem cell biology
    • Horton SJ, Huntly BJ. Recent advances in acute myeloid leukemia stem cell biology. Haematologica 2012; 97: 966-974.
    • (2012) Haematologica , vol.97 , pp. 966-974
    • Horton, S.J.1    Huntly, B.J.2
  • 129
    • 84877589557 scopus 로고    scopus 로고
    • Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia
    • Craddock C, Quek L, Goardon N, Freeman S, Siddique S, Raghavan M et al. Azacitidine fails to eradicate leukemic stem/progenitor cell populations in patients with acute myeloid leukemia and myelodysplasia. Leukemia 2013; 27: 1028-1036.
    • (2013) Leukemia , vol.27 , pp. 1028-1036
    • Craddock, C.1    Quek, L.2    Goardon, N.3    Freeman, S.4    Siddique, S.5    Raghavan, M.6
  • 130
    • 77950809059 scopus 로고    scopus 로고
    • A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
    • Sharma SV, Lee DY, Li B, Quinlan MP, Takahashi F, Maheswaran S et al. A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations. Cell 2010; 141: 69-80.
    • (2010) Cell , vol.141 , pp. 69-80
    • Sharma, S.V.1    Lee, D.Y.2    Li, B.3    Quinlan, M.P.4    Takahashi, F.5    Maheswaran, S.6
  • 131
    • 84891842006 scopus 로고    scopus 로고
    • Origins of aberrant DNA methylation in acute myeloid leukemia
    • Schoofs T, Berdel WE, Müller-Tidow C. Origins of aberrant DNA methylation in acute myeloid leukemia. Leukemia 2014; 28: 1-14.
    • (2014) Leukemia , vol.28 , pp. 1-14
    • Schoofs, T.1    Berdel, W.E.2    Müller-Tidow, C.3
  • 132
  • 133
    • 84858988409 scopus 로고    scopus 로고
    • Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration
    • Zhu NL, Asahina K, Wang J, Ueno A, Lazaro R, Miyaoka Y et al. Hepatic stellate cell-derived delta-like homolog 1 (DLK1) protein in liver regeneration. J Biol Chem 2012; 287: 10355-10367.
    • (2012) J Biol Chem , vol.287 , pp. 10355-10367
    • Zhu, N.L.1    Asahina, K.2    Wang, J.3    Ueno, A.4    Lazaro, R.5    Miyaoka, Y.6
  • 134
    • 84893917461 scopus 로고    scopus 로고
    • Leukaemogenesis induced by an activating -catenin mutation in osteoblasts
    • Kode A, Manavalan JS, Mosialou I, Bhagat G, Rathinam CV, Luo N et al. Leukaemogenesis induced by an activating -catenin mutation in osteoblasts. Nature 2014; 506: 240-244.
    • (2014) Nature , vol.506 , pp. 240-244
    • Kode, A.1    Manavalan, J.S.2    Mosialou, I.3    Bhagat, G.4    Rathinam, C.V.5    Luo, N.6
  • 135
    • 84918538918 scopus 로고    scopus 로고
    • Refining the role of adult stem cells as cancer cells of origin
    • White AC, Lowry WE. Refining the role of adult stem cells as cancer cells of origin. Trends Cell Biol 2015; 25: 11-20.
    • (2015) Trends Cell Biol , vol.25 , pp. 11-20
    • White, A.C.1    Lowry, W.E.2
  • 136
    • 78751676408 scopus 로고    scopus 로고
    • Cells of origin in cancer
    • Visvader JE. Cells of origin in cancer. Nature 2011; 469: 314-322.
    • (2011) Nature , vol.469 , pp. 314-322
    • Visvader, J.E.1
  • 137
    • 84902480315 scopus 로고    scopus 로고
    • Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
    • Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S et al. Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo. Cancer Cell 2014; 25: 794-808.
    • (2014) Cancer Cell , vol.25 , pp. 794-808
    • Woll, P.S.1    Kjällquist, U.2    Chowdhury, O.3    Doolittle, H.4    Wedge, D.C.5    Thongjuea, S.6
  • 138
    • 84894245627 scopus 로고    scopus 로고
    • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 2014; 506: 328-333.
    • (2014) Nature , vol.506 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3    Chen, W.C.4    Brandwein, J.M.5    Gupta, V.6
  • 139
    • 84894304555 scopus 로고    scopus 로고
    • Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
    • Corces-Zimmerman MR, Hong WJ, Weissman IL, Medeiros BC, Majeti R. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci USA 2014; 111: 2548-2553.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. 2548-2553
    • Corces-Zimmerman, M.R.1    Hong, W.J.2    Weissman, I.L.3    Medeiros, B.C.4    Majeti, R.5
  • 140
  • 141
    • 84879698783 scopus 로고    scopus 로고
    • Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia
    • Abdel-Wahab O, Levine RL. Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia. Blood 2013; 121: 3563-3572.
    • (2013) Blood , vol.121 , pp. 3563-3572
    • Abdel-Wahab, O.1    Levine, R.L.2


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