Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 40, 2014, Pages 14512-14517

  Boucher, Jeremie ^a,d   Charalambous, Marika ^b   Zarse, Kim ^a,c   Mori, Marcelo A ^a   Kleinridders, Andre ^a   Ristow, Michael ^c   Ferguson Smith, Anne C ^b   Kahn, C Ronald ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ETH ZURICH   (Switzerland)

^d ASTRAZENECA R AND D   (Sweden)

Author keywords

Developmental control; Diabetes; Transcriptional control

Indexed keywords

ARGONAUTE 2 PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1C; DICER; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; HISTONE H3; INSULIN RECEPTOR; MESSENGER RNA; MICRORNA; NECDIN; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZAC1; UNCLASSIFIED DRUG; UNTRANSLATED RNA; ZINC FINGER PROTEIN; ZINC FINGER PROTEIN 57; AZACITIDINE; ENZYME INHIBITOR; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; INSULIN; SOMATOMEDIN C; TRICHOSTATIN A;

ANIMAL EXPERIMENT; ANIMAL TISSUE; BROWN ADIPOSE TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; DNA METHYLATION; GENE EXPRESSION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING; ANIMAL; CELL CULTURE; CYTOLOGY; DEFICIENCY; DNA MICROARRAY; DRUG EFFECTS; FIBROBLAST; GENE EXPRESSION PROFILING; GENETICS; GENOME IMPRINTING; KNOCKOUT MOUSE; MAMMALIAN EMBRYO; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSFORMED CELL LINE;

ADIPOSE TISSUE, BROWN; ANIMALS; AZACITIDINE; CELL LINE, TRANSFORMED; CELLS, CULTURED; DNA METHYLATION; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; FIBROBLASTS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOMIC IMPRINTING; HISTONE DEACETYLASE INHIBITORS; HYDROXAMIC ACIDS; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MICE, KNOCKOUT; MICRORNAS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84930576840     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1415475111     Document Type: Article

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