A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis

Human Molecular Genetics

Volumn 16, Issue 3, 2007, Pages 343-354

  Hancock, Anne L ^a   Brown, Keith W ^a   Moorwood, Kim ^a,e   Moon, Hanlim ^b   Holmgren, Claes ^b   Mardikar, Sudhanshu H ^c   Dallosso, Anthony R ^a   Klenova, Elena ^d   Loukinov, Dmitri ^b   Ohlsson, Rolf ^c   Lobanenkov, Victor V ^b   Malik, Karim ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSITY OF ESSEX   (United Kingdom)

^e University of Bath   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; WT1 PROTEIN;

ALLELE; ARTICLE; CARCINOGENESIS; CHROMOSOME 11P; CONTROLLED STUDY; CPG ISLAND; DATA ANALYSIS; DNA METHYLATION; EPIGENETICS; GENE CONTROL; GENE EXPRESSION; GENOME IMPRINTING; HUMAN; HUMAN CELL; KIDNEY DEVELOPMENT; NEPHROBLASTOMA; PRIORITY JOURNAL; PROMOTER REGION; SILENCER ELEMENT; TRANSCRIPTION REGULATION;

CELLS, CULTURED; DNA METHYLATION; DNA-BINDING PROTEINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, WILMS TUMOR; GENOMIC IMPRINTING; HUMANS; KIDNEY; KIDNEY NEOPLASMS; MODELS, BIOLOGICAL; PROTEIN ISOFORMS; REPRESSOR PROTEINS; SILENCER ELEMENTS, TRANSCRIPTIONAL; WILMS TUMOR;

EID: 33847253548     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl478     Document Type: Article

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