Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 7, 2014, Pages 2548-2553

  Corces Zimmerman, M Ryan ^a   Hong, Wan Jen ^a,b   Weissman, Irving L ^a   Medeiros, Bruno C ^b   Majeti, Ravindra ^a,b  

^a Institute for Stem Cell Biology and Regenerative Medicine   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Clonal evolution; Preleukemia

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; AMPLICON; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; EXOME; GENE FREQUENCY; GENOTYPE; HEMATOPOIETIC STEM CELL; HISTONE MODIFICATION; HUMAN; HUMAN CELL; INDUCTION CHEMOTHERAPY; LEUKEMIA REMISSION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PRELEUKEMIA; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC MUTATION;

CLONAL EVOLUTION; PRELEUKEMIA;

ANTIGENS, CD34; BASE SEQUENCE; CLONAL EVOLUTION; EPIGENESIS, GENETIC; EXOME; FLOW CYTOMETRY; GENOTYPE; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; PRELEUKEMIA; SEQUENCE ANALYSIS, DNA;

EID: 84894304555     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1324297111     Document Type: Article

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