-
1
-
-
34548715822
-
Cell-specific expression of wild-type MeCP2 in mouse models of Rett syndrome yields insight about pathogenesis
-
Alvarez-Saavedra, M., et al. Cell-specific expression of wild-type MeCP2 in mouse models of Rett syndrome yields insight about pathogenesis. Hum. Mol. Genet. 16 (2007), 2315–2325.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 2315-2325
-
-
Alvarez-Saavedra, M.1
-
2
-
-
77953533210
-
Elevated expression of MeCP2 in cardiac and skeletal tissues is detrimental for normal development
-
Alvarez-Saavedra, M., et al. Elevated expression of MeCP2 in cardiac and skeletal tissues is detrimental for normal development. Hum. Mol. Genet. 19 (2010), 2177–2190.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 2177-2190
-
-
Alvarez-Saavedra, M.1
-
4
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir, R.E., et al. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 23 (1999), 185–188.
-
(1999)
Nat. Genet.
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
-
5
-
-
29144440149
-
Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome
-
Asaka, Y., et al. Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol. Dis. 21 (2006), 217–227.
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 217-227
-
-
Asaka, Y.1
-
6
-
-
60749102039
-
Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology
-
Ballas, N., et al. Non-cell autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology. Nat. Neurosci. 12 (2009), 311–317.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 311-317
-
-
Ballas, N.1
-
7
-
-
84888348687
-
TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement
-
Bialas, A.R., Stevens, B., TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement. Nat. Neurosci. 16 (2013), 1773–1782.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1773-1782
-
-
Bialas, A.R.1
Stevens, B.2
-
8
-
-
84859233352
-
Pharmacological interference with the glucocorticoid system influences symptoms and lifespan in a mouse model of Rett syndrome
-
Braun, S., et al. Pharmacological interference with the glucocorticoid system influences symptoms and lifespan in a mouse model of Rett syndrome. Hum. Mol. Genet. 21 (2012), 1673–1680.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1673-1680
-
-
Braun, S.1
-
9
-
-
84883390784
-
A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome
-
Buchovecky, C.M., et al. A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome. Nat. Genet. 45 (2013), 1013–1020.
-
(2013)
Nat. Genet.
, vol.45
, pp. 1013-1020
-
-
Buchovecky, C.M.1
-
10
-
-
35648978121
-
The story of Rett syndrome: from clinic to neurobiology
-
Chahrour, M., Zoghbi, H.Y., The story of Rett syndrome: from clinic to neurobiology. Neuron 56 (2007), 422–437.
-
(2007)
Neuron
, vol.56
, pp. 422-437
-
-
Chahrour, M.1
Zoghbi, H.Y.2
-
11
-
-
45849105557
-
MeCP2, a key contributor to neurological disease, activates and represses transcription
-
Chahrour, M., et al. MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320 (2008), 1224–1229.
-
(2008)
Science
, vol.320
, pp. 1224-1229
-
-
Chahrour, M.1
-
12
-
-
34748831111
-
MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number
-
Chao, H.T., et al. MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron 56 (2007), 58–65.
-
(2007)
Neuron
, vol.56
, pp. 58-65
-
-
Chao, H.T.1
-
13
-
-
78149431869
-
Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes
-
Chao, H.T., et al. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature 468 (2010), 263–269.
-
(2010)
Nature
, vol.468
, pp. 263-269
-
-
Chao, H.T.1
-
14
-
-
0035093830
-
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice
-
Chen, R.Z., et al. Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat. Genet. 27 (2001), 327–331.
-
(2001)
Nat. Genet.
, vol.27
, pp. 327-331
-
-
Chen, R.Z.1
-
15
-
-
84875818042
-
Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression
-
Chen, Y., et al. Creb1-Mecp2-(m)CpG complex transactivates postnatal murine neuronal glucose transporter isoform 3 expression. Endocrinology 154 (2013), 1598–1611.
-
(2013)
Endocrinology
, vol.154
, pp. 1598-1611
-
-
Chen, Y.1
-
16
-
-
77955145342
-
Genetic association between methyl-CpG binding protein 2 (MECP2) and primary Sjogren's syndrome
-
Cobb, B.L., et al. Genetic association between methyl-CpG binding protein 2 (MECP2) and primary Sjogren's syndrome. Ann. Rheum. Dis. 69 (2010), 1731–1732.
-
(2010)
Ann. Rheum. Dis.
, vol.69
, pp. 1731-1732
-
-
Cobb, B.L.1
-
17
-
-
80053579176
-
Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function
-
Cohen, S., et al. Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. Neuron 72 (2011), 72–85.
-
(2011)
Neuron
, vol.72
, pp. 72-85
-
-
Cohen, S.1
-
18
-
-
84928175766
-
Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli
-
Cronk, J.C., et al. Methyl-CpG Binding Protein 2 Regulates Microglia and Macrophage Gene Expression in Response to Inflammatory Stimuli. Immunity 42 (2015), 679–691.
-
(2015)
Immunity
, vol.42
, pp. 679-691
-
-
Cronk, J.C.1
-
19
-
-
84894438035
-
Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in Rett syndrome
-
Cuddapah, V.A., et al. Methyl-CpG-binding protein 2 (MECP2) mutation type is associated with disease severity in Rett syndrome. J. Med. Genet. 51 (2014), 152–158.
-
(2014)
J. Med. Genet.
, vol.51
, pp. 152-158
-
-
Cuddapah, V.A.1
-
20
-
-
84874586343
-
Microglia regulate the number of neural precursor cells in the developing cerebral cortex
-
Cunningham, C.L., et al. Microglia regulate the number of neural precursor cells in the developing cerebral cortex. J. Neurosci. 33 (2013), 4216–4233.
-
(2013)
J. Neurosci.
, vol.33
, pp. 4216-4233
-
-
Cunningham, C.L.1
-
21
-
-
73349128157
-
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines
-
Dandrea, M., et al. MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. Nucleic Acids Res. 37 (2009), 6681–6690.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 6681-6690
-
-
Dandrea, M.1
-
22
-
-
84886654275
-
Tissue-resident macrophages
-
Davies, L.C., et al. Tissue-resident macrophages. Nat. Immunol. 14 (2013), 986–995.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 986-995
-
-
Davies, L.C.1
-
23
-
-
84897523047
-
Inflammatory lung disease in Rett syndrome
-
De Felice, C., et al. Inflammatory lung disease in Rett syndrome. Mediat. Inflamm., 2014, 2014, 560120.
-
(2014)
Mediat. Inflamm.
, vol.2014
, pp. 560120
-
-
De Felice, C.1
-
24
-
-
84859454582
-
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
-
Derecki, N.C., et al. Wild-type microglia arrest pathology in a mouse model of Rett syndrome. Nature 484 (2012), 105–109.
-
(2012)
Nature
, vol.484
, pp. 105-109
-
-
Derecki, N.C.1
-
25
-
-
33845772985
-
Recurrent infections, hypotonia, and mental retardation caused by duplication of MECP2 and adjacent region in Xq28
-
Friez, M.J., et al. Recurrent infections, hypotonia, and mental retardation caused by duplication of MECP2 and adjacent region in Xq28. Pediatrics 118 (2006), e1687–e1695.
-
(2006)
Pediatrics
, vol.118
, pp. e1687-e1695
-
-
Friez, M.J.1
-
26
-
-
63049122784
-
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
-
Ghisletti, S., et al. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev. 23 (2009), 681–693.
-
(2009)
Genes Dev.
, vol.23
, pp. 681-693
-
-
Ghisletti, S.1
-
27
-
-
33846924001
-
Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2
-
Giacometti, E., et al. Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2. Proc. Natl. Acad. Sci. U. S. A. 104 (2007), 1931–1936.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 1931-1936
-
-
Giacometti, E.1
-
28
-
-
27144484259
-
Neurophysiology of Rett syndrome
-
Glaze, D.G., Neurophysiology of Rett syndrome. J. Child Neurol. 20 (2005), 740–746.
-
(2005)
J. Child Neurol.
, vol.20
, pp. 740-746
-
-
Glaze, D.G.1
-
29
-
-
84897440230
-
Mitochondrial dysfunction in the skeletal muscle of a mouse model of Rett syndrome (RTT): implications for the disease phenotype
-
Gold, W.A., et al. Mitochondrial dysfunction in the skeletal muscle of a mouse model of Rett syndrome (RTT): implications for the disease phenotype. Mitochondrion 15 (2014), 10–17.
-
(2014)
Mitochondrion
, vol.15
, pp. 10-17
-
-
Gold, W.A.1
-
30
-
-
84886953273
-
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
-
Goldmann, T., et al. A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation. Nat. Neurosci. 16 (2013), 1618–1626.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 1618-1626
-
-
Goldmann, T.1
-
31
-
-
0035094767
-
A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome
-
Guy, J., et al. A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat. Genet. 27 (2001), 322–326.
-
(2001)
Nat. Genet.
, vol.27
, pp. 322-326
-
-
Guy, J.1
-
32
-
-
33847266846
-
Reversal of neurological defects in a mouse model of Rett syndrome
-
Guy, J., et al. Reversal of neurological defects in a mouse model of Rett syndrome. Science 315 (2007), 1143–1147.
-
(2007)
Science
, vol.315
, pp. 1143-1147
-
-
Guy, J.1
-
33
-
-
80054047383
-
The role of MeCP2 in the brain
-
Guy, J., et al. The role of MeCP2 in the brain. Annu. Rev. Cell Dev. Biol. 27 (2011), 631–652.
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 631-652
-
-
Guy, J.1
-
34
-
-
0020507697
-
A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases
-
Hagberg, B., et al. A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases. Ann. Neurol. 14 (1983), 471–479.
-
(1983)
Ann. Neurol.
, vol.14
, pp. 471-479
-
-
Hagberg, B.1
-
35
-
-
84907746150
-
Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone
-
Haim, Y.O., et al. Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone. Sci. Rep., 4, 2014, 4323.
-
(2014)
Sci. Rep.
, vol.4
, pp. 4323
-
-
Haim, Y.O.1
-
36
-
-
84864520051
-
Modeling an autism risk factor in mice leads to permanent immune dysregulation
-
Hsiao, E.Y., et al. Modeling an autism risk factor in mice leads to permanent immune dysregulation. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 12776–12781.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 12776-12781
-
-
Hsiao, E.Y.1
-
37
-
-
33846839170
-
Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains
-
Itoh, M., et al. Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains. J. Neuropathol. Exp. Neurol. 66 (2007), 117–123.
-
(2007)
J. Neuropathol. Exp. Neurol.
, vol.66
, pp. 117-123
-
-
Itoh, M.1
-
38
-
-
84896103307
-
MeCP2 reinforces STAT3 signaling and the generation of effector CD4 + T cells by promoting miR-124-mediated suppression of SOCS5
-
Jiang, S., et al. MeCP2 reinforces STAT3 signaling and the generation of effector CD4 + T cells by promoting miR-124-mediated suppression of SOCS5. Sci. Signal., 7, 2014, ra25.
-
(2014)
Sci. Signal.
, vol.7
, pp. ra25
-
-
Jiang, S.1
-
39
-
-
84922513388
-
Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity
-
Jin, L.W., et al. Dysregulation of glutamine transporter SNAT1 in Rett syndrome microglia: a mechanism for mitochondrial dysfunction and neurotoxicity. J. Neurosci. 35 (2015), 2516–2529.
-
(2015)
J. Neurosci.
, vol.35
, pp. 2516-2529
-
-
Jin, L.W.1
-
40
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones, P.L., et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19 (1998), 187–191.
-
(1998)
Nat. Genet.
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
-
41
-
-
84873744778
-
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups
-
Kaufman, K.M., et al. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann. Rheum. Dis. 72 (2013), 437–444.
-
(2013)
Ann. Rheum. Dis.
, vol.72
, pp. 437-444
-
-
Kaufman, K.M.1
-
42
-
-
7244243971
-
MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions
-
Kishi, N., Macklis, J.D., MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions. Mol. Cell. Neurosci. 27 (2004), 306–321.
-
(2004)
Mol. Cell. Neurosci.
, vol.27
, pp. 306-321
-
-
Kishi, N.1
Macklis, J.D.2
-
43
-
-
84875946223
-
Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse
-
Koelsch, K.A., et al. Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse. J. Autoimmun. 41 (2013), 168–174.
-
(2013)
J. Autoimmun.
, vol.41
, pp. 168-174
-
-
Koelsch, K.A.1
-
44
-
-
78149306478
-
Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid predendritic cells (pDCs)
-
Lepelletier, Y., et al. Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid predendritic cells (pDCs). Blood 116 (2010), 3389–3397.
-
(2010)
Blood
, vol.116
, pp. 3389-3397
-
-
Lepelletier, Y.1
-
45
-
-
0000341684
-
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus
-
Lerner, M.R., Steitz, J.A., Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc. Natl. Acad. Sci. U. S. A. 76 (1979), 5495–5499.
-
(1979)
Proc. Natl. Acad. Sci. U. S. A.
, vol.76
, pp. 5495-5499
-
-
Lerner, M.R.1
Steitz, J.A.2
-
46
-
-
84903950937
-
MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation
-
Li, C., et al. MeCP2 enforces Foxp3 expression to promote regulatory T cells' resilience to inflammation. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), E2807–E2816.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. E2807-E2816
-
-
Li, C.1
-
47
-
-
79960907896
-
A role for glia in the progression of Rett's syndrome
-
Lioy, D.T., et al. A role for glia in the progression of Rett's syndrome. Nature 475 (2011), 497–500.
-
(2011)
Nature
, vol.475
, pp. 497-500
-
-
Lioy, D.T.1
-
48
-
-
84867688629
-
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses
-
Litvak, V., et al. A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses. Nature 490 (2012), 421–425.
-
(2012)
Nature
, vol.490
, pp. 421-425
-
-
Litvak, V.1
-
49
-
-
1942533500
-
Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice
-
Luikenhuis, S., et al. Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 6033–6038.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6033-6038
-
-
Luikenhuis, S.1
-
50
-
-
84883462358
-
Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor
-
Lyst, M.J., et al. Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor. Nat. Neurosci. 16 (2013), 898–902.
-
(2013)
Nat. Neurosci.
, vol.16
, pp. 898-902
-
-
Lyst, M.J.1
-
51
-
-
77951020598
-
Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate
-
Maezawa, I., Jin, L.W., Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate. J. Neurosci. 30 (2010), 5346–5356.
-
(2010)
J. Neurosci.
, vol.30
, pp. 5346-5356
-
-
Maezawa, I.1
Jin, L.W.2
-
52
-
-
65549144456
-
Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions
-
Maezawa, I., et al. Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J. Neurosci. 29 (2009), 5051–5061.
-
(2009)
J. Neurosci.
, vol.29
, pp. 5051-5061
-
-
Maezawa, I.1
-
53
-
-
78149488365
-
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto, M.C., et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 143 (2010), 527–539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
-
54
-
-
79960075356
-
Adult neural function requires MeCP2
-
McGraw, C.M., et al. Adult neural function requires MeCP2. Science, 333, 2011, 186.
-
(2011)
Science
, vol.333
, pp. 186
-
-
McGraw, C.M.1
-
55
-
-
0026658662
-
Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA
-
Meehan, R.R., et al. Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. Nucleic Acids Res. 20 (1992), 5085–5092.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 5085-5092
-
-
Meehan, R.R.1
-
56
-
-
84871563384
-
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
Mellen, M., et al. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 151 (2012), 1417–1430.
-
(2012)
Cell
, vol.151
, pp. 1417-1430
-
-
Mellen, M.1
-
57
-
-
30644479042
-
Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome
-
Moretti, P., et al. Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome. J. Neurosci. 26 (2006), 319–327.
-
(2006)
J. Neurosci.
, vol.26
, pp. 319-327
-
-
Moretti, P.1
-
58
-
-
84865702920
-
Gastrointestinal and nutritional problems occur frequently throughout life in girls and women with Rett syndrome
-
Motil, K.J., et al. Gastrointestinal and nutritional problems occur frequently throughout life in girls and women with Rett syndrome. J. Pediatr. Gastroenterol. Nutr. 55 (2012), 292–298.
-
(2012)
J. Pediatr. Gastroenterol. Nutr.
, vol.55
, pp. 292-298
-
-
Motil, K.J.1
-
59
-
-
84907312653
-
Low bone mineral mass is associated with decreased bone formation and diet in girls with Rett syndrome
-
Motil, K.J., et al. Low bone mineral mass is associated with decreased bone formation and diet in girls with Rett syndrome. J. Pediatr. Gastroenterol. Nutr. 59 (2014), 386–392.
-
(2014)
J. Pediatr. Gastroenterol. Nutr.
, vol.59
, pp. 386-392
-
-
Motil, K.J.1
-
60
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan, X., et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393 (1998), 386–389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
-
61
-
-
78650903501
-
Rett syndrome: revised diagnostic criteria and nomenclature
-
Neul, J.L., et al. Rett syndrome: revised diagnostic criteria and nomenclature. Ann. Neurol. 68 (2010), 944–950.
-
(2010)
Ann. Neurol.
, vol.68
, pp. 944-950
-
-
Neul, J.L.1
-
62
-
-
84952877388
-
Developmental delay in Rett syndrome: data from the natural history study
-
Neul, J.L., et al. Developmental delay in Rett syndrome: data from the natural history study. J. Neurodev. Disord., 6, 2014, 20.
-
(2014)
J. Neurodev. Disord.
, vol.6
, pp. 20
-
-
Neul, J.L.1
-
63
-
-
84888242980
-
Oligodendrocyte lineage cells contribute unique features to Rett syndrome neuropathology
-
Nguyen, M.V., et al. Oligodendrocyte lineage cells contribute unique features to Rett syndrome neuropathology. J. Neurosci. 33 (2013), 18764–18774.
-
(2013)
J. Neurosci.
, vol.33
, pp. 18764-18774
-
-
Nguyen, M.V.1
-
64
-
-
26444516160
-
Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome
-
Nuber, U.A., et al. Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome. Hum. Mol. Genet. 14 (2005), 2247–2256.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 2247-2256
-
-
Nuber, U.A.1
-
65
-
-
84888373081
-
MeCP2 deficiency enhances glutamate release through NF-kappaB signaling in myeloid derived cells
-
O'Driscoll, C.M., et al. MeCP2 deficiency enhances glutamate release through NF-kappaB signaling in myeloid derived cells. J. Neuroimmunol. 265 (2013), 61–67.
-
(2013)
J. Neuroimmunol.
, vol.265
, pp. 61-67
-
-
O'Driscoll, C.M.1
-
66
-
-
24144465889
-
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
-
Ogawa, S., et al. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell 122 (2005), 707–721.
-
(2005)
Cell
, vol.122
, pp. 707-721
-
-
Ogawa, S.1
-
67
-
-
84860015853
-
Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome
-
Okabe, Y., et al. Alterations of gene expression and glutamate clearance in astrocytes derived from an MeCP2-null mouse model of Rett syndrome. PLoS One, 7, 2012, e35354.
-
(2012)
PLoS One
, vol.7
, pp. e35354
-
-
Okabe, Y.1
-
68
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
Paolicelli, R.C., et al. Synaptic pruning by microglia is necessary for normal brain development. Science 333 (2011), 1456–1458.
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
-
69
-
-
0014011176
-
On a unusual brain atrophy syndrome in hyperammonemia in childhood
-
Rett, A., On a unusual brain atrophy syndrome in hyperammonemia in childhood. Wien. Med. Wochenschr. 116 (1966), 723–726.
-
(1966)
Wien. Med. Wochenschr.
, vol.116
, pp. 723-726
-
-
Rett, A.1
-
70
-
-
44849101156
-
A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome
-
Samaco, R.C., et al. A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome. Hum. Mol. Genet. 17 (2008), 1718–1727.
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 1718-1727
-
-
Samaco, R.C.1
-
71
-
-
76049091733
-
Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities
-
Samaco, R.C., et al. Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 21966–21971.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 21966-21971
-
-
Samaco, R.C.1
-
72
-
-
45849119873
-
Common variants within MECP2 confer risk of systemic lupus erythematosus
-
Sawalha, A.H., et al. Common variants within MECP2 confer risk of systemic lupus erythematosus. PLoS One, 3, 2008, e1727.
-
(2008)
PLoS One
, vol.3
, pp. e1727
-
-
Sawalha, A.H.1
-
73
-
-
84861427387
-
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
-
Schafer, D.P., et al. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron 74 (2012), 691–705.
-
(2012)
Neuron
, vol.74
, pp. 691-705
-
-
Schafer, D.P.1
-
74
-
-
34547890019
-
Functions of site-specific histone acetylation and deacetylation
-
Shahbazian, M.D., Grunstein, M., Functions of site-specific histone acetylation and deacetylation. Annu. Rev. Biochem. 76 (2007), 75–100.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 75-100
-
-
Shahbazian, M.D.1
Grunstein, M.2
-
75
-
-
0036917867
-
Rett syndrome and MeCP2: linking epigenetics and neuronal function
-
Shahbazian, M.D., Zoghbi, H.Y., Rett syndrome and MeCP2: linking epigenetics and neuronal function. Am. J. Hum. Genet. 71 (2002), 1259–1272.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 1259-1272
-
-
Shahbazian, M.D.1
Zoghbi, H.Y.2
-
76
-
-
76849094693
-
Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state
-
Skene, P.J., et al. Neuronal MeCP2 is expressed at near histone-octamer levels and globally alters the chromatin state. Mol. Cell 37 (2010), 457–468.
-
(2010)
Mol. Cell
, vol.37
, pp. 457-468
-
-
Skene, P.J.1
-
77
-
-
36849076770
-
The classical complement cascade mediates CNS synapse elimination
-
Stevens, B., et al. The classical complement cascade mediates CNS synapse elimination. Cell 131 (2007), 1164–1178.
-
(2007)
Cell
, vol.131
, pp. 1164-1178
-
-
Stevens, B.1
-
78
-
-
0037180492
-
Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain
-
Tudor, M., et al. Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain. Proc. Natl. Acad. Sci. U. S. A. 99 (2002), 15536–15541.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 15536-15541
-
-
Tudor, M.1
-
79
-
-
56649107908
-
Mecp2-null mice provide new neuronal targets for Rett syndrome
-
Urdinguio, R.G., et al. Mecp2-null mice provide new neuronal targets for Rett syndrome. PLoS One, 3, 2008, e3669.
-
(2008)
PLoS One
, vol.3
, pp. e3669
-
-
Urdinguio, R.G.1
-
80
-
-
0031590442
-
Dexamethasone and interleukin-1 potently synergize to stimulate the production of granulocyte colony-stimulating factor in differentiated THP-1 cells
-
Wang, Y., et al. Dexamethasone and interleukin-1 potently synergize to stimulate the production of granulocyte colony-stimulating factor in differentiated THP-1 cells. Biochem. Biophys. Res. Commun. 239 (1997), 676–680.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.239
, pp. 676-680
-
-
Wang, Y.1
-
81
-
-
65249109807
-
Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus
-
Webb, R., et al. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum. 60 (2009), 1076–1084.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1076-1084
-
-
Webb, R.1
-
82
-
-
84898441524
-
Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons
-
Williams, E.C., et al. Mutant astrocytes differentiated from Rett syndrome patients-specific iPSCs have adverse effects on wild-type neurons. Hum. Mol. Genet. 23 (2014), 2968–2980.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 2968-2980
-
-
Williams, E.C.1
-
83
-
-
84944737090
-
Glucocorticoid augments lipopolysaccharide-induced activation of the IkappaBzeta-dependent genes encoding the anti-microbial glycoproteins lipocalin 2 and pentraxin 3
-
Yamazaki, S., et al. Glucocorticoid augments lipopolysaccharide-induced activation of the IkappaBzeta-dependent genes encoding the anti-microbial glycoproteins lipocalin 2 and pentraxin 3. J. Biochem. 157:5 (2015), 399–410.
-
(2015)
J. Biochem.
, vol.157
, Issue.5
, pp. 399-410
-
-
Yamazaki, S.1
-
84
-
-
84865547244
-
Nuclear factor-kappaB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome
-
Yan, Q., et al. Nuclear factor-kappaB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 14140–14145.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 14140-14145
-
-
Yan, Q.1
-
85
-
-
84870720893
-
Overexpression of methyl-CpG binding protein 2 impairs T(H)1 responses
-
(163ra158)
-
Yang, T., et al. Overexpression of methyl-CpG binding protein 2 impairs T(H)1 responses. Sci. Transl. Med., 4, 2012 (163ra158).
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Yang, T.1
-
86
-
-
37649022627
-
Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes
-
Yasui, D.H., et al. Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc. Natl. Acad. Sci. U. S. A. 104 (2007), 19416–19421.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 19416-19421
-
-
Yasui, D.H.1
-
87
-
-
84886298903
-
MeCP2 modulates gene expression pathways in astrocytes
-
Yasui, D.H., et al. MeCP2 modulates gene expression pathways in astrocytes. Mol. Autism, 4, 2013, 3.
-
(2013)
Mol. Autism
, vol.4
, pp. 3
-
-
Yasui, D.H.1
-
88
-
-
84897401619
-
Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase
-
Zhang, J., et al. Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase. Neuron 82 (2014), 195–207.
-
(2014)
Neuron
, vol.82
, pp. 195-207
-
-
Zhang, J.1
|