Oligodendrocyte lineage cells contribute unique features to rett syndrome neuropathology

Journal of Neuroscience

Volumn 33, Issue 48, 2013, Pages 18764-18774

  Nguyen, Minh Vu Chuong ^a   Felice, Christy A ^a   Du, Fang ^a   Covey, Matthew V ^a   Robinson, John K ^a   Mandel, Gail ^b   Ballas, Nurit ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYL CPG BINDING PROTEIN 2; PROTEOLIPID PROTEIN; MECP2 PROTEIN, MOUSE; MYELIN BASIC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BEHAVIOR DISORDER; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR ACTIVITY; MOTOR PERFORMANCE; MOUSE; NONHUMAN; OLIGODENDROGLIA; OPEN FIELD TEST; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETT SYNDROME; SCORING SYSTEM; WESTERN BLOTTING; ANIMAL; ASTROCYTE; DARKNESS; GENETICS; HAND STRENGTH; HINDLIMB; LIGHT; LOCOMOTION; MUTATION; PATHOLOGY; PHENOTYPE; PHYSIOLOGY;

ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELL LINEAGE; DARKNESS; FEMALE; HAND STRENGTH; HINDLIMB; IMMUNOHISTOCHEMISTRY; LIGHT; LOCOMOTION; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MUTATION; MYELIN BASIC PROTEIN; OLIGODENDROGLIA; PHENOTYPE; POLYMERASE CHAIN REACTION; RETT SYNDROME;

EID: 84888242980     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2657-13.2013     Document Type: Article

References (31)

1. Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet 23:185-188. CrossRef Medline
2. Ballas N, Lioy DT, Grunseich C, Mandel G (2009) Non-cell-autonomous influence of MeCP2-deficient glia on neuronal dendritic morphology. Nat Neurosci 12:311-317. CrossRef Medline
3. Baumann N, Pham-Dinh D (2001) Biology of oligodendrocyte and myelin in the mammalian central nervous system. Physiol Rev 81:871-927. Medline
4. Bergles DE, Jabs R, Steinhäuser C (2010) Neuron-glia synapses in the brain. Brain Res Rev 63:130-137. CrossRef Medline
5. Chahrour M, Zoghbi HY (2007) The story of Rett syndrome: from clinic to neurobiology. Neuron 56:422-437. CrossRef Medline
6. Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY (2010) Dysfunction in GABA signalling mediates autismlike stereotypies and Rett syndrome phenotypes. Nature 468:263-269. CrossRef Medline
7. Chen RZ, Akbarian S, Tudor M, Jaenisch R (2001) Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice. Nat Genet 27:327-331. CrossRef Medline
8. Cheval H, Guy J, Merusi C, De Sousa D, Selfridge J, Bird A (2012) Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows. Hum Mol Genet 21:3806-3814. CrossRef Medline
9. Derecki NC, Cronk JC, Lu Z, Xu E, Abbott SB, Guyenet PG, Kipnis J (2012) Wild-type microglia arrest pathology in a mouse model of Rett syndrome. Nature 484:105-109. CrossRef Medline
10. Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, Moretti P, McGill BE, Goulding EH, Sullivan E, Tecott LH, Zoghbi HY (2008) Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress. Neuron 59:947-958. CrossRef Medline
11. Gourine AV, Kasymov V, Marina N, Tang F, Figueiredo MF, Lane S, Teschemacher AG, Spyer KM, Deisseroth K, Kasparov S (2010) Astrocytes control breathing through pH-dependent release of ATP. Science 329:571-575. CrossRef Medline
12. Guy J, Hendrich B, Holmes M, Martin JE, Bird A (2001) A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome. Nat Genet 27:322-326. CrossRef Medline
13. Guy J, Gan J, Selfridge J, Cobb S, Bird A (2007) Reversal of neurological defects in a mouse model of Rett syndrome. Science 315:1143-1147. CrossRef Medline
14. Hagberg B (2002) Clinical manifestations and stages of Rett syndrome. Ment Retard Dev Disabil Res Rev 8:61-65. CrossRef Medline
15. Jahn O, Tenzer S, Werner HB (2009) Myelin proteomics: molecular anatomy of an insulating sheath. Mol Neurobiol 40:55-72. CrossRef Medline
16. Komitova M, Zhu X, Serwanski DR, Nishiyama A (2009) NG2 cells are distinct from neurogenic cells in the postnatal mouse subventricular zone. J Comp Neurol 512:702-716. CrossRef Medline
17. Lioy DT, Garg SK, Monaghan CE, Raber J, Foust KD, Kaspar BK, Hirrlinger PG, Kirchhoff F, Bissonnette JM, Ballas N, Mandel G (2011) A role for glia in the progression of Rett's syndrome. Nature 475:497-500. CrossRef Medline
18. Maezawa I, Jin LW (2010) Rett syndrome microglia damage dendrites and synapses by the elevated release of glutamate. J Neurosci 30:5346-5356. CrossRef Medline
19. McGill BE, Bundle SF, Yaylaoglu MB, Carson JP, Thaller C, Zoghbi HY (2006) Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome. Proc Natl Acad Sci U S A 103:18267-18272. CrossRef Medline
20. McGraw CM, Samaco RC, Zoghbi HY (2011) Adult neural function requires MeCP2. Science 333:186. CrossRef Medline
21. Nguyen MV, Du F, Felice CA, Shan X, Nigam A, Mandel G, Robinson JK, Ballas N (2012) MeCP2 is critical for maintaining mature neuronal networks and global brain anatomy during late stages of postnatal brain development and in the mature adult brain. J Neurosci 32:10021-10034. CrossRef Medline
22. Robinson L, Guy J, McKay L, Brockett E, Spike RC, Selfridge J, De Sousa D, Merusi C, Riedel G, Bird A, Cobb SR (2012) Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome. Brain 135:2699-2710. CrossRef Medline
23. Samaco RC, Fryer JD, Ren J, Fyffe S, Chao HT, Sun Y, Greer JJ, Zoghbi HY, Neul JL (2008) A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome. Hum Mol Genet 17:1718-1727. CrossRef Medline
24. Santos M, Silva-Fernandes A, Oliveira P, Sousa N, Maciel P (2007) Evidence for abnormal early development in a mouse model of Rett syndrome. Genes Brain Behav 6:277-286. CrossRef Medline
25. Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J, Armstrong D, Paylor R, Zoghbi H (2002) Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron 35:243-254. CrossRef Medline
26. Stearns NA, Schaevitz LR, Bowling H, Nag N, Berger UV, Berger-Sweeney J (2007) Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome. Neuroscience 146:907-921. CrossRef Medline
27. Stevens B, Porta S, Haak LL, Gallo V, Fields RD (2002) Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials. Neuron 36:855-868. CrossRef Medline
28. Tao J, Hu K, Chang Q, Wu H, Sherman NE, Martinowich K, Klose RJ, Schanen C, Jaenisch R, Wang W, Sun YE (2009) Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proc Natl Acad Sci U S A 106:4882-4887. CrossRef Medline
29. Temudo T, Santos M, Ramos E, Dias K, Vieira JP, Moreira A, Calado E, Carrilho I, Oliveira G, Levy A, Barbot C, Fonseca M, Cabral A, Cabral P, Monteiro J, Borges L, Gomes R, Mira G, Pereira SA, Santos M, et al. (2011) Rett syndrome with and without detected MECP2 mutations: an attempt to redefine phenotypes. Brain Dev 33:69-76. CrossRef Medline
30. Wake H, Lee PR, Fields RD (2011) Control of local protein synthesis and initial events in myelination by action potentials. Science 333:1647-1651. CrossRef Medline
31. Zhu X, Bergles DE, Nishiyama A (2008) NG2 cells generate both oligodendrocytes and gray matter astrocytes. Development 135:145-157. CrossRef Medline