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Volumn 27, Issue 3, 2001, Pages 322-326

A mouse Mecp2-null mutation causes neurological symptoms that mimic rett syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN FUNCTION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; EMBRYO DEVELOPMENT; FEMALE; GENE MUTATION; GENE SILENCING; HETEROZYGOSITY; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETT SYNDROME; SEX DIFFERENCE; X CHROMOSOMAL INHERITANCE;

EID: 0035094767     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/85899     Document Type: Article
Times cited : (1277)

References (31)
  • 3
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • (1999) Nature Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1
  • 4
    • 17444440488 scopus 로고    scopus 로고
    • Influence of mutation type and X chromosome inactivation on Rett syndrome phenotypes
    • (2000) Ann. Neurol. , vol.47 , pp. 670-679
    • Amir, R.E.1
  • 5
    • 0033365401 scopus 로고    scopus 로고
    • Rett syndrome and beyond: Recurrent spontaneous and familial MECP2 mutations at CpG hotspots
    • (1999) Am. J. Hum. Genet. , vol.65 , pp. 1520-1529
    • Wan, M.1
  • 6
  • 7
    • 18144443930 scopus 로고    scopus 로고
    • Long-read sequence analysis of the MECP2 gene in Rett syndrome patients: Correlation of disease severity with mutation type and location
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 1119-1129
    • Cheadle, J.P.1
  • 10
    • 0033854457 scopus 로고    scopus 로고
    • Mutation analysis of the methyl-CpG-binding protein 2 gene (MECP2) in patients with Rett syndrome
    • (2000) J. Med. Genet. , vol.37 , pp. 608-610
    • Obata, K.1
  • 12
    • 0033646567 scopus 로고    scopus 로고
    • Diagnostic testing for Rett syndrome by DHPLC and direct sequencing analysis of the MECP2 gene: Identification of several novel mutations and polymorphisms
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1428-1436
    • Buyse, I.M.1
  • 13
    • 0026747761 scopus 로고
    • Purification, sequence and cellular localization of a novel chromosomal protein that binds to methylated DNA
    • (1992) Cell , vol.69 , pp. 905-914
    • Lewis, J.D.1
  • 15
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • (1997) Cell , vol.88 , pp. 471-481
    • Nan, X.1    Campoy, J.2    Bird, A.3
  • 16
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1
  • 17
    • 0031837109 scopus 로고    scopus 로고
    • Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
    • (1998) Nature Genet. , vol.19 , pp. 187-191
    • Jones, P.L.1
  • 20
    • 0032871399 scopus 로고    scopus 로고
    • MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
    • (1999) Nature Genet. , vol.23 , pp. 58-61
    • Ng, H.-H.1
  • 23
    • 0032842478 scopus 로고    scopus 로고
    • Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety
    • (1999) Nature Genet. , vol.23 , pp. 99-103
    • Tronche, F.1
  • 25
    • 0032772371 scopus 로고    scopus 로고
    • Methylation-mediated transcriptional silencing in euchromatin by methyl-CpG binding protein MBD1 isoforms
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6415-6426
    • Fujita, N.1
  • 27
    • 0009703087 scopus 로고    scopus 로고
    • Behavioural phenotypes of inbred mouse strains: Implications and recommendations for molecular studies
    • (1997) Psychopharmacology , vol.132 , pp. 107-124
    • Crawley, J.N.1
  • 31
    • 0031255352 scopus 로고    scopus 로고
    • Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment
    • (1997) Mamm. Genome , vol.8 , pp. 711-713
    • Rogers, D.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.