MeCP2 deficiency enhances glutamate release through NF-κB signaling in myeloid derived cells

Journal of Neuroimmunology

Volumn 265, Issue 1-2, 2013, Pages 61-67

  O'Driscoll, Cliona M ^a,b   Kaufmann, Walter E ^a,c   Bressler, Joseph P ^a,b  

^a Hugo Moser Research Institute at Kennedy Krieger   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glutamate; MeCP2; Microglia; NF B; Peripheral blood mononuclear cells

Indexed keywords

GLUTAMIC ACID; GLUTAMINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JSH 23; LIPOPOLYSACCHARIDE; MESSENGER RNA; METHYL CPG BINDING PROTEIN 2; PROTEIN INHIBITOR; QUINAZOLINE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL ISOLATION; CONTROLLED STUDY; DRUG TARGETING; GLS GENE; GLUTAMATE RELEASE; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MALE; MECP2 GENE; MICROGLIAL CELL CULTURE; MOUSE; NEUROMODULATION; NEWBORN; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN SECRETION; PROTEIN TARGETING; RETT SYNDROME; TH1 CELL; TRANSCRIPTION REGULATION;

GLUTAMATE; MECP2; MICROGLIA; NF-ΚB; PERIPHERAL BLOOD MONONUCLEAR CELLS;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD11B; BETA-GALACTOSIDASE; BRAIN; CELLS, CULTURED; ENZYME INHIBITORS; GLUTAMIC ACID; GLUTAMINASE; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MICROGLIA; MYELOID CELLS; NF-KAPPA B; NITRIC OXIDE; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84888373081     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2013.09.002     Document Type: Article

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