A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

Nature

Volumn 490, Issue 7420, 2012, Pages 421-425

  Litvak, Vladimir ^a   Ratushny, Alexander V ^a,b   Lampano, Aaron E ^a   Schmitz, Frank ^a   Huang, Albert C ^b   Raman, Ayush ^b   Rust, Alistair G ^c   Bergthaler, Andreas ^d   Aitchison, John D ^a,b   Aderem, Alan ^a  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON REGULATORY FACTOR 7; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR FKHRL1;

ANTIMICROBIAL ACTIVITY; GENE EXPRESSION; GENOME; PHYSIOLOGICAL RESPONSE; RODENT;

ANIMAL CELL; ANTIVIRAL RESPONSE; GENE CONTROL; GENE DELETION; GENE REGULATORY NETWORK; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; IMMUNE RESPONSE; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE DELETION; GENE EXPRESSION REGULATION; INFLAMMATION; INTERFERON REGULATORY FACTOR-7; INTERFERON TYPE I; LUNG; MACROPHAGES; MICE; MICE, INBRED C57BL; REPRODUCIBILITY OF RESULTS; VESICULOVIRUS;

MUS;

EID: 84867688629     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11428     Document Type: Review

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