MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions

Molecular and Cellular Neuroscience

Volumn 27, Issue 3, 2004, Pages 306-321

  Kishi, Noriyuki ^a   Macklis, Jeffrey D ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYL CPG BINDING PROTEIN 2;

ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL FATE; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; DENDRITIC CELL; EMBRYO; IN VITRO STUDY; IN VIVO STUDY; MACROGLIA; MOUSE; MOUSE STRAIN; NEOCORTEX; NERVE CELL DIFFERENTIATION; NEUROBLAST; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; STATISTICAL SIGNIFICANCE; STRAIN DIFFERENCE; WILD TYPE;

ANIMALS; CELL MOVEMENT; CELLS, CULTURED; CHROMOSOMAL PROTEINS, NON-HISTONE; DENDRITES; DNA-BINDING PROTEINS; FEMALE; MALE; METHYL-CPG-BINDING PROTEIN 2; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; REPRESSOR PROTEINS;

EID: 7244243971     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2004.07.006     Document Type: Article

References (76)

1. R.E. Amir, I.B. Van den Veyver, M. Wan, C.Q. Tran, U. Francke, and H.Y. Zoghbi Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 Nat. Genet. 23 1999 185 188
2. D.D. Armstrong Neuropathology of Rett syndrome Ment. Retard. Dev. Disabil. Res. Rev. 8 2002 72 76
3. D. Armstrong, J.K. Dunn, B. Antalffy, and R. Trivedi Selective dendritic alterations in the cortex of Rett syndrome J. Neuropathol. Exp. Neurol. 54 1995 195 201
4. M.L. Bauman, T.L. Kemper, and D.M. Arin Microscopic observations of the brain in Rett syndrome Neuropediatrics 26 1995 105 108
5. M.L. Bauman, T.L. Kemper, and D.M. Arin Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome Neurology 45 1995 1581 1586
6. P.V. Belichenko, A. Oldfors, B. Hagberg, and A. Dahlstrom Rett syndrome: 3-D confocal microscopy of cortical pyramidal dendrites and afferents NeuroReport 5 1994 1509 1513
7. A. Bird DNA methylation patterns and epigenetic memory Genes Dev. 16 2002 6 21
8. H.A. Cameron, and R. McKay Stem cells and neurogenesis in the adult brain Curr. Opin. Neurobiol. 8 1998 677 680
9. M.F. Casanova, S. Naidu, T.E. Goldberg, H.W. Moser, S. Khoromi, A. Kumar, J.E. Kleinman, and D.R. Weinberger Quantitative magnetic resonance imaging in Rett syndrome J. Neuropsychiatry Clin. Neurosci. 3 1991 66 72
10. S. Cassel, M.O. Revel, C. Kelche, and J. Zwiller Expression of the methyl-CpG-binding protein MeCP2 in rat brain. An ontogenetic study Neurobiol. Dis. 15 2004 206 211
11. R.Z. Chen, S. Akbarian, M. Tudor, and R. Jaenisch Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice Nat. Genet. 27 2001 327 331
12. W.G. Chen, Q. Chang, Y. Lin, A. Meissner, A.E. West, E.C. Griffith, R. Jaenisch, and M.E. Greenberg Depression of BDNF Transcription involves calcium-dependent phosphorylation of MECP2 Science 302 2003 885 889
13. J. Christodoulou, A. Grimm, T. Maher, and B. Bennetts RettBASE: the IRSA MECP2 variation database-A new mutation database in evolution Hum. Mutat. 21 2003 466 472
14. D.R. Cohen, V. Matarazzo, A.M. Palmer, Y. Tu, O.H. Jeon, J. Pevsner, and G.V. Ronnett Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis Mol. Cell. Neurosci. 22 2003 417 429
15. F. Conti, and T. Manzoni The neurotransmitters and postsynaptic actions of callosally projecting neurons Behav. Brain Res. 64 1994 37 53
16. J.F. Coy, Z. Sedlacek, D. Bachner, H. Delius, and A. Poustka A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3″-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression Hum. Mol. Genet. 8 1999 1253 1262
17. E. Debus, K. Weber, and M. Osborn Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides Differentiation 25 1983 193 203
18. B. Egaas, E. Courchesne, and O. Saitoh Reduced size of corpus callosum in autism Arch. Neurol. 52 1995 794 801
19. A. Escayg, B.T. MacDonald, M.H. Meisler, S. Baulac, G. Huberfeld, I. An-Gourfinkel, A. Brice, E. LeGuern, B. Moulard, D. Chaigne, C. Buresi, and A. Malafosse Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2 Nat. Genet. 24 2000 343 345
20. M.K. Floeter, and E.G. Jones The morphology and phased outgrowth of callosal axons in the fetal rat Brain Res. 354 1985 7 18
21. F. Francis, A. Koulakoff, D. Boucher, P. Chafey, B. Schaar, M.C. Vinet, G. Friocourt, N. McDonnell, O. Reiner, A. Kahn, S.K. McConnell, Y. Berwald-Netter, P. Denoulet, and J. Chelly Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons Neuron 23 1999 247 256
22. M. Frotscher Cajal-Retzius cells, Reelin, and the formation of layers Curr. Opin. Neurobiol. 8 1998 570 575
23. F.H. Gage Mammalian neural stem cells Science 287 2000 1433 1438
24. M.A. Gates, C.C. Tai, and J.D. Macklis Neocortical neurons lacking the protein-tyrosine kinase B receptor display abnormal differentiation and process elongation in vitro and in vivo Neuroscience 98 2000 437 447
25. P.T. Georgel, R.A. Horowitz-Scherer, N. Adkins, C.L. Woodcock, P.A. Wade, and J.C. Hansen Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation J. Biol. Chem. 278 2003 32181 32188
26. D.G. Glaze Neurophysiology of Rett syndrome Ment. Retard. Dev. Disabil. Res. Rev. 8 2002 66 71
27. J.G. Gleeson, P.T. Lin, L.A. Flanagan, and C.A. Walsh Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons Neuron 23 1999 257 271
28. J.A. Gorski, S.R. Zeiler, S. Tamowski, and K.R. Jones Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites J. Neurosci. 23 2003 6856 6865
29. H. Gotoh, I. Suzuki, K. Maruki, M. Mitomo, K. Hirasawa, and N. Sasaki Magnetic resonance imaging and clinical findings examined in adulthood-studies on three adults with Rett syndrome Brain Dev. 23 Suppl. 1 2001 S118 S121
30. J. Guy, B. Hendrich, M. Holmes, J.E. Martin, and A. Bird A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome Nat. Genet. 27 2001 322 326
31. B. Hagberg Clinical manifestations and stages of Rett syndrome Ment. Retard. Dev. Disabil. Res. Rev. 8 2002 61 65
32. R. Hulspas, C. Tiarks, J. Reilly, C.C. Hsieh, L. Recht, and P.J. Quesenberry In vitro cell density-dependent clonal growth of EGF-responsive murine neural progenitor cells under serum-free conditions Exp. Neurol. 148 1997 147 156
33. T.M. Jessell, and J.R. Sanes Development. The decade of the developing brain Curr. Opin. Neurobiol. 10 2000 599 611
34. K.K. Johe, T.G. Hazel, T. Muller, M.M. Dugich-Djordjevic, and R.D. McKay Single factors direct the differentiation of stem cells from the fetal and adult central nervous system Genes Dev. 10 1996 3129 3140
35. B.P. Jung, D.G. Jugloff, G. Zhang, R. Logan, S. Brown, and J.H. Eubanks The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells J. Neurobiol. 55 2003 86 96
36. D. Kligman, and D.C. Hilt The S100 protein family Trends Biochem. Sci. 13 1988 437 443
37. S. Kriaucionis, and A. Bird DNA methylation and Rett syndrome Hum. Mol. Genet. 12 Suppl. 2 2003 R221 R227
38. S. Kriaucionis, and A. Bird The major form of MeCP2 has a novel N-terminus generated by alternative splicing Nucleic Acids Res. 32 2004 1818 1823
39. U. Lendahl, L.B. Zimmerman, and R.D. McKay CNS stem cells express a new class of intermediate filament protein Cell 60 1990 585 595
40. J.D. Lewis, R.R. Meehan, W.J. Henzel, I. Maurer-Fogy, P. Jeppesen, F. Klein, and A. Bird Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA Cell 69 1992 905 914
41. S. Luikenhuis, E. Giacometti, C.F. Beard, and R. Jaenisch Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice Proc. Natl. Acad. Sci. U. S. A. 101 2004 6033 6038
42. V.V. Lunyak, R. Burgess, G.G. Prefontaine, C. Nelson, S.H. Sze, J. Chenoweth, P. Schwartz, P.A. Pevzner, C. Glass, G. Mandel, and M.G. Rosenfeld Corepressor-dependent silencing of chromosomal regions encoding neuronal genes Science 298 2002 1747 1752
43. S.S. Magavi, B.R. Leavitt, and J.D. Macklis Induction of neurogenesis in the neocortex of adult mice Nature 405 2000 951 955
44. K. Martinowich, D. Hattori, H. Wu, S. Fouse, F. He, Y. Hu, G. Fan, and Y.E. Sun DNA-methylation-related chromatin remodeling in activity-dependent BDNF gene regulation Science 302 2003 890 893
45. M.F. Marusich, H.M. Furneaux, P.D. Henion, and J.A. Weston Hu neuronal proteins are expressed in proliferating neurogenic cells J. Neurobiol. 25 1994 143 155
46. V. Matarazzo, and G.V. Ronnett Temporal and regional differences in the olfactory proteome as a consequence of MeCP2 deficiency Proc. Natl. Acad. Sci. U. S. A. 101 2004 7763 7768
47. R. McKay Stem cells and the cellular organization of the brain J. Neurosci. Res. 59 2000 298 300
48. E.K. Miller The prefrontal cortex and cognitive control Nat. Rev., Neurosci. 1 2000 59 65
49. G.N. Mnatzakanian, H. Lohi, I. Munteanu, S.E. Alfred, T. Yamada, P.J. MacLeod, J.R. Jones, S.W. Scherer, N.C. Schanen, M.J. Friez, J.B. Vincent, and B.A. Minassian A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome Nat. Genet. 36 2004 339 341
50. U. Moog, E.E. Smeets, K.E. van Roozendaal, S. Schoenmakers, J. Herbergs, A.M. Schoonbrood-Lenssen, and C.T. Schrander-Stumpel Neurodevelopmental disorders in males related to the gene causing Rett syndrome in females (MECP2) Eur. J. Paediatr. Neurol. 7 2003 5 12
51. D.K. Morest, and R.R. Morest Perfusion-fixation of the brain with chrome-osmium solutions for the rapid Golgi method Am. J. Anat. 118 1966 811 831
52. C.M. Morshead, and D. van der Kooy A new 'spin' on neural stem cells? Curr. Opin. Neurobiol. 11 2001 59 65
53. B.C. Mullaney, M.V. Johnston, and M.E. Blue Developmental expression of methyl-CpG binding protein 2 is dynamically regulated in the rodent brain Neuroscience 123 2004 939 949
54. R.J. Mullen, C.R. Buck, and A.M. Smith NeuN, a neuronal specific nuclear protein in vertebrates Development 116 1992 201 211
55. S. Naidu, W.E. Kaufmann, M.T. Abrams, G.D. Pearlson, D.C. Lanham, K.A. Fredericksen, P.B. Barker, A. Horska, X. Golay, S. Mori, D.F. Wong, M. Yablonski, H.W. Moser, and M.V. Johnston Neuroimaging studies in Rett syndrome Brain Dev. 23 Suppl. 1 2001 S62 S71
56. X. Nan, F.J. Campoy, and A. Bird MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin Cell 88 1997 471 481
57. X. Nan, H.H. Ng, C.A. Johnson, C.D. Laherty, B.M. Turner, R.N. Eisenman, and A. Bird Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex Nature 393 1998 386 389
58. R. Planells-Cases, M. Caprini, J. Zhang, E.M. Rockenstein, R.R. Rivera, C. Murre, E. Masliah, and M. Montal Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice Biophys. J. 78 2000 2878 2891
59. B.A. Reynolds, and S. Weiss Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell Dev. Biol. 175 1996 1 13
60. B.A. Reynolds, W. Tetzlaff, and S. Weiss A multipotent EGF-responsive striatal embryonic progenitor cell produces neurons and astrocytes J. Neurosci. 12 1992 4565 4574
61. M.D. Shahbazian, and H.Y. Zoghbi Rett syndrome and MeCP2: linking epigenetics and neuronal function Am. J. Hum. Genet. 71 2002 1259 1272
62. M. Shahbazian, J. Young, L. Yuva-Paylor, C. Spencer, B. Antalffy, J. Noebels, D. Armstrong, R. Paylor, and H. Zoghbi Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3 Neuron 35 2002 243 254
63. M.D. Shahbazian, B. Antalffy, D.L. Armstrong, and H.Y. Zoghbi Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation Hum. Mol. Genet. 11 2002 115 124
64. D.A. Sholl Dendritic organization in the neurons of the visual and motor cortices of the cat J. Anat. 87 1953 387 406
65. I. Sommer, and M. Schachner Cell that are O4 antigen-positive and O1 antigen-negative differentiate into O1 antigen-positive oligodendrocytes Neurosci. Lett. 29 1982 183 188
66. R. Spreafico, C. Frassoni, P. Arcelli, M. Selvaggio, and S. De Biasi In situ labeling of apoptotic cell death in the cerebral cortex and thalamus of rats during development J. Comp. Neurol. 363 1995 281 295
67. T.J. Sprinkle 2′,3′-Cyclic nucleotide 3′- phosphodiesterase, an oligodendrocyte-Schwann cell and myelin-associated enzyme of the nervous system Crit. Rev. Neurobiol. 4 1989 235 301
68. I. Stancheva, A.L. Collins, I.B. Van den Veyver, H. Zoghbi, and R.R. Meehan A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by Notch in Xenopus embryos Mol. Cell 12 2003 425 435
69. H. Super, E. Soriano, and H.B. Uylings The functions of the preplate in development and evolution of the neocortex and hippocampus Brain Res. Brain Res. Rev. 27 1998 40 64
70. T. Takizawa, K. Nakashima, M. Namihira, W. Ochiai, A. Uemura, M. Yanagisawa, N. Fujita, M. Nakao, and T. Taga DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain Dev. Cell 1 2001 749 758
71. P. Taupin, and F.H. Gage Adult neurogenesis and neural stem cells of the central nervous system in mammals J. Neurosci. Res. 69 2002 745 749
72. R.P. Tucker The roles of microtubule-associated proteins in brain morphogenesis: a review Brain Res. Brain Res. Rev. 15 1990 101 120
73. D. van der Kooy, and S. Weiss Why stem cells? Science 287 2000 1439 1441
74. R.H. Wallace, D.W. Wang, R. Singh, I.E. Scheffer, A.L. George Jr., H.A. Phillips, K. Saar, A. Reis, E.W. Johnson, G.R. Sutherland, S.F. Berkovic, and J.C. Mulley Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B Nat. Genet. 19 1998 366 370
75. B. Xu, K. Zang, N.L. Ruff, Y.A. Zhang, S.K. McConnell, M.P. Stryker, and L.F. Reichardt Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB Neuron 26 2000 233 245
76. X. Zhao, T. Ueba, B.R. Christie, B. Barkho, M.J. McConnell, K. Nakashima, E.S. Lein, B.D. Eadie, A.R. Willhoite, A.R. Muotri, R.G. Summers, J. Chun, K.F. Lee, and F.H. Gage Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function Proc. Natl. Acad. Sci. U. S. A. 100 2003 6777 6782