-
1
-
-
78751662679
-
Type 1 diabetes: etiology, immunology, and therapeutic strategies
-
PID: 21248163, COI: 1:CAS:528:DC%2BC3MXisVChtrc%3D
-
van Belle TL, Coppieters KT, von Herrath MG (2011) Type 1 diabetes: etiology, immunology, and therapeutic strategies. Physiol Rev 91:79–118
-
(2011)
Physiol Rev
, vol.91
, pp. 79-118
-
-
van Belle, T.L.1
Coppieters, K.T.2
von Herrath, M.G.3
-
2
-
-
0022617990
-
Type I, diabetes mellitus. A chronic autoimmune disease
-
PID: 3517648, COI: 1:STN:280:DyaL283gtlCrsw%3D%3D
-
Eisenbarth GS (1986) Type I, diabetes mellitus. A chronic autoimmune disease. N Engl J Med 314:1360–1368
-
(1986)
N Engl J Med
, vol.314
, pp. 1360-1368
-
-
Eisenbarth, G.S.1
-
3
-
-
84875211293
-
Mechanistic basis of immunotherapies for type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC3sXjt1Sjsrk%3D
-
Chen W, Xie A, Chan L (2013) Mechanistic basis of immunotherapies for type 1 diabetes mellitus. Transl Res: J Lab Clin Med 161:217–229
-
(2013)
Transl Res : J Lab Clin Med
, vol.161
, pp. 217-229
-
-
Chen, W.1
Xie, A.2
Chan, L.3
-
4
-
-
84875248649
-
Is autoimmune diabetes caused by aberrant immune activity or defective suppression of physiological self-reactivity?
-
PID: 23277162, COI: 1:CAS:528:DC%2BC3sXntFaisg%3D%3D
-
Askenasy EM, Askenasy N (2013) Is autoimmune diabetes caused by aberrant immune activity or defective suppression of physiological self-reactivity? Autoimmun Rev 12:633–637
-
(2013)
Autoimmun Rev
, vol.12
, pp. 633-637
-
-
Askenasy, E.M.1
Askenasy, N.2
-
5
-
-
0037025990
-
Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice
-
PID: 12163565, COI: 1:CAS:528:DC%2BD38XmtVOhtLg%3D
-
Gagnerault MC, Luan JJ, Lotton C, Lepault F (2002) Pancreatic lymph nodes are required for priming of beta cell reactive T cells in NOD mice. J Exp Med 196:369–377
-
(2002)
J Exp Med
, vol.196
, pp. 369-377
-
-
Gagnerault, M.C.1
Luan, J.J.2
Lotton, C.3
Lepault, F.4
-
6
-
-
84888202996
-
PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses
-
PID: 24012345, COI: 1:CAS:528:DC%2BC3sXhsVKksbjF
-
Xiao J, Liu C, Li G, Peng S, Hu J, Qu L et al (2013) PDCD5 negatively regulates autoimmunity by upregulating FOXP3(+) regulatory T cells and suppressing Th17 and Th1 responses. J Autoimmun 47:34–44
-
(2013)
J Autoimmun
, vol.47
, pp. 34-44
-
-
Xiao, J.1
Liu, C.2
Li, G.3
Peng, S.4
Hu, J.5
Qu, L.6
-
7
-
-
84884902115
-
Autoimmunity in 2012
-
PID: 23975606, COI: 1:CAS:528:DC%2BC3sXhsVymurnK
-
Selmi C (2013) Autoimmunity in 2012. Clin Rev Allergy Immunol 45:290–301
-
(2013)
Clin Rev Allergy Immunol
, vol.45
, pp. 290-301
-
-
Selmi, C.1
-
8
-
-
84884287627
-
Treg and CTLA-4: two intertwining pathways to immune tolerance
-
PID: 23849743, COI: 1:CAS:528:DC%2BC3sXhtV2rtLvI
-
Walker LS (2013) Treg and CTLA-4: two intertwining pathways to immune tolerance. J Autoimmun 45:49–57
-
(2013)
J Autoimmun
, vol.45
, pp. 49-57
-
-
Walker, L.S.1
-
9
-
-
84875943027
-
T-regs in autoimmune hepatitis-systemic lupus erythematosus/mixed connective tissue disease overlap syndrome are functionally defective and display a Th1 cytokine profile
-
PID: 23287048, COI: 1:CAS:528:DC%2BC3sXhtVOisw%3D%3D
-
Longhi MS, Ma Y, Grant CR, Samyn M, Gordon P, Mieli-Vergani G et al (2013) T-regs in autoimmune hepatitis-systemic lupus erythematosus/mixed connective tissue disease overlap syndrome are functionally defective and display a Th1 cytokine profile. J Autoimmun 41:146–151
-
(2013)
J Autoimmun
, vol.41
, pp. 146-151
-
-
Longhi, M.S.1
Ma, Y.2
Grant, C.R.3
Samyn, M.4
Gordon, P.5
Mieli-Vergani, G.6
-
10
-
-
84858768465
-
Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression
-
PID: 22222887, COI: 1:CAS:528:DC%2BC38XlvVyisbo%3D
-
Peterson RA (2012) Regulatory T-cells: diverse phenotypes integral to immune homeostasis and suppression. Toxicol Pathol 40:186–204
-
(2012)
Toxicol Pathol
, vol.40
, pp. 186-204
-
-
Peterson, R.A.1
-
11
-
-
77954141914
-
FOXP3+ regulatory T cells in the human immune system
-
PID: 20559327, COI: 1:CAS:528:DC%2BC3cXnsFKitLY%3D
-
Sakaguchi S, Miyara M, Costantino CM, Hafler DA (2010) FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol 10:490–500
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 490-500
-
-
Sakaguchi, S.1
Miyara, M.2
Costantino, C.M.3
Hafler, D.A.4
-
12
-
-
80052869960
-
Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes
-
PID: 21831659, COI: 1:CAS:528:DC%2BC3MXhtF2gsL%2FL
-
Battaglia M, Roncarolo MG (2011) Immune intervention with T regulatory cells: past lessons and future perspectives for type 1 diabetes. Semin Immunol 23:182–194
-
(2011)
Semin Immunol
, vol.23
, pp. 182-194
-
-
Battaglia, M.1
Roncarolo, M.G.2
-
13
-
-
39449126502
-
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
-
PID: 18285775, COI: 1:CAS:528:DC%2BD1cXitVOjt7o%3D
-
Tang Q, Bluestone JA (2008) The Foxp3+ regulatory T cell: a jack of all trades, master of regulation. Nat Immunol 9:239–244
-
(2008)
Nat Immunol
, vol.9
, pp. 239-244
-
-
Tang, Q.1
Bluestone, J.A.2
-
14
-
-
84869863632
-
Identification of a human Th1-like IFNgamma-secreting Treg subtype deriving from effector T cells
-
PID: 22824211, COI: 1:CAS:528:DC%2BC38XhtV2itL7P
-
Venigalla RK, Guttikonda PJ, Eckstein V, Ho AD, Sertel S, Lorenz HM et al (2012) Identification of a human Th1-like IFNgamma-secreting Treg subtype deriving from effector T cells. J Autoimmun 39:377–387
-
(2012)
J Autoimmun
, vol.39
, pp. 377-387
-
-
Venigalla, R.K.1
Guttikonda, P.J.2
Eckstein, V.3
Ho, A.D.4
Sertel, S.5
Lorenz, H.M.6
-
15
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
PID: 12612578, COI: 1:CAS:528:DC%2BD3sXitlyqs74%3D
-
Fontenot JD, Gavin MA, Rudensky AY (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4:330–336
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
16
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
COI: 1:CAS:528:DC%2BD3sXhtFarsbw%3D
-
Hori S, Nomura T, Sakaguchi S (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science (New York, NY) 299:1057–1061
-
(2003)
Science (New York, NY)
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
17
-
-
33746330703
-
Transforming growth factor-beta and T-cell-mediated immunoregulation in the control of autoimmune diabetes
-
PID: 16903915, COI: 1:CAS:528:DC%2BD28XpvFegtL4%3D
-
You S, Thieblemont N, Alyanakian MA, Bach JF, Chatenoud L (2006) Transforming growth factor-beta and T-cell-mediated immunoregulation in the control of autoimmune diabetes. Immunol Rev 212:185–202
-
(2006)
Immunol Rev
, vol.212
, pp. 185-202
-
-
You, S.1
Thieblemont, N.2
Alyanakian, M.A.3
Bach, J.F.4
Chatenoud, L.5
-
18
-
-
0014792798
-
Cell interactions in the induction of tolerance: the role of thymic lymphocytes
-
PID: 4911896, COI: 1:STN:280:DyaE3c3gs1yhsg%3D%3D
-
Gershon RK, Kondo K (1970) Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology 18:723–737
-
(1970)
Immunology
, vol.18
, pp. 723-737
-
-
Gershon, R.K.1
Kondo, K.2
-
19
-
-
0016588326
-
The stimulation of specific suppressor T cells in genetic non-responder mice by linear random copolymers of L-amino acids
-
PID: 52219, COI: 1:CAS:528:DyaE28XktVeltLk%3D
-
Benacerraf B, Kapp JA, Debre P, Pierce CW, de la Croix F (1975) The stimulation of specific suppressor T cells in genetic non-responder mice by linear random copolymers of L-amino acids. Transplant Rev 26:21–38
-
(1975)
Transplant Rev
, vol.26
, pp. 21-38
-
-
Benacerraf, B.1
Kapp, J.A.2
Debre, P.3
Pierce, C.W.4
de la Croix, F.5
-
20
-
-
0025132213
-
Control of diabetes in NOD mice by suppressor cells
-
PID: 2140263
-
Bach JF, Boitard C, Yasunami R, Dardenne M (1990) Control of diabetes in NOD mice by suppressor cells. J Autoimmun 3(Suppl 1):97–100
-
(1990)
J Autoimmun
, vol.3
, pp. 97-100
-
-
Bach, J.F.1
Boitard, C.2
Yasunami, R.3
Dardenne, M.4
-
21
-
-
0024500755
-
T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
-
PID: 2523954, COI: 1:STN:280:DyaL1M3jsFGrtA%3D%3D
-
Boitard C, Yasunami R, Dardenne M, Bach JF (1989) T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J Exp Med 169:1669–1680
-
(1989)
J Exp Med
, vol.169
, pp. 1669-1680
-
-
Boitard, C.1
Yasunami, R.2
Dardenne, M.3
Bach, J.F.4
-
22
-
-
79955038372
-
Pillars article: immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995. J Immunol (Baltimore
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M (2011) Pillars article: immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995. J Immunol (Baltimore, Md: 1950), 186:3808–3821
-
(2011)
Md
, vol.1950
, Issue.186
, pp. 3808-3821
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
23
-
-
0034679560
-
Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
-
PID: 10899917, COI: 1:CAS:528:DC%2BD3cXkvFGiu7c%3D
-
Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N et al (2000) Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 192:303–310
-
(2000)
J Exp Med
, vol.192
, pp. 303-310
-
-
Takahashi, T.1
Tagami, T.2
Yamazaki, S.3
Uede, T.4
Shimizu, J.5
Sakaguchi, N.6
-
24
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
PID: 9670041, COI: 1:CAS:528:DyaK1cXkvVaqt7g%3D
-
Thornton AM, Shevach EM (1998) CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 188:287–296
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
25
-
-
0033985780
-
Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
-
COI: 1:CAS:528:DC%2BD3cXisVyk
-
Thornton AM, Shevach EM (2000) Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol (Baltimore, Md: 1950) 164:183–190
-
(2000)
J Immunol (Baltimore, Md: 1950)
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
26
-
-
25444510061
-
Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice
-
PID: 16126946, COI: 1:CAS:528:DC%2BD2MXhtFakt7fP
-
Piccirillo CA, Tritt M, Sgouroudis E, Albanese A, Pyzik M, Hay V (2005) Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice. Ann N Y Acad Sci 1051:72–87
-
(2005)
Ann N Y Acad Sci
, vol.1051
, pp. 72-87
-
-
Piccirillo, C.A.1
Tritt, M.2
Sgouroudis, E.3
Albanese, A.4
Pyzik, M.5
Hay, V.6
-
27
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
PID: 12612581, COI: 1:CAS:528:DC%2BD3sXitlyqs7s%3D
-
Khattri R, Cox T, Yasayko SA, Ramsdell F (2003) An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol 4:337–342
-
(2003)
Nat Immunol
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
28
-
-
84875936395
-
FOXP3: genetic and epigenetic implications for autoimmunity
-
PID: 23313429, COI: 1:CAS:528:DC%2BC3sXovFemug%3D%3D
-
Katoh H, Zheng P, Liu Y (2013) FOXP3: genetic and epigenetic implications for autoimmunity. J Autoimmun 41:72–78
-
(2013)
J Autoimmun
, vol.41
, pp. 72-78
-
-
Katoh, H.1
Zheng, P.2
Liu, Y.3
-
29
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
PID: 15184499, COI: 1:CAS:528:DC%2BD2cXkvV2jsLg%3D
-
Tang Q, Henriksen KJ, Bi M, Finger EB, Szot G, Ye J et al (2004) In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 199:1455–1465
-
(2004)
J Exp Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
-
30
-
-
4344657757
-
CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion
-
COI: 1:CAS:528:DC%2BD2cXmvVCrurg%3D
-
Sarween N, Chodos A, Raykundalia C, Khan M, Abbas AK, Walker LS (2004) CD4+CD25+ cells controlling a pathogenic CD4 response inhibit cytokine differentiation, CXCR-3 expression, and tissue invasion. J Immunol (Baltimore, Md: 1950) 173:2942–2951
-
(2004)
J Immunol (Baltimore, Md: 1950)
, vol.173
, pp. 2942-2951
-
-
Sarween, N.1
Chodos, A.2
Raykundalia, C.3
Khan, M.4
Abbas, A.K.5
Walker, L.S.6
-
31
-
-
12744262844
-
Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes
-
PID: 15591438, COI: 1:CAS:528:DC%2BD2MXhsVCrs7g%3D
-
Jaeckel E, von Boehmer H, Manns MP (2005) Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes 54:306–310
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
von Boehmer, H.2
Manns, M.P.3
-
32
-
-
0037099613
-
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
PID: 12119348, COI: 1:CAS:528:DC%2BD38XlsV2ms7s%3D
-
Piccirillo CA, Letterio JJ, Thornton AM, McHugh RS, Mamura M, Mizuhara H et al (2002) CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness. J Exp Med 196:237–246
-
(2002)
J Exp Med
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
-
33
-
-
33645786794
-
Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo
-
COI: 1:CAS:528:DC%2BD28XjtV2gsLo%3D
-
Weber SE, Harbertson J, Godebu E, Mros GA, Padrick RC, Carson BD et al (2006) Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo. J Immunol (Baltimore, Md: 1950) 176:4730–4739
-
(2006)
J Immunol (Baltimore, Md: 1950)
, vol.176
, pp. 4730-4739
-
-
Weber, S.E.1
Harbertson, J.2
Godebu, E.3
Mros, G.A.4
Padrick, R.C.5
Carson, B.D.6
-
34
-
-
63249133189
-
All-trans retinoic acid inhibits type 1 diabetes by T regulatory (Treg)-dependent suppression of interferon-gamma-producing T-cells without affecting Th17 cells
-
PID: 18984738, COI: 1:CAS:528:DC%2BD1MXptVCgtg%3D%3D
-
Van YH, Lee WH, Ortiz S, Lee MH, Qin HJ, Liu CP (2009) All-trans retinoic acid inhibits type 1 diabetes by T regulatory (Treg)-dependent suppression of interferon-gamma-producing T-cells without affecting Th17 cells. Diabetes 58:146–155
-
(2009)
Diabetes
, vol.58
, pp. 146-155
-
-
Van, Y.H.1
Lee, W.H.2
Ortiz, S.3
Lee, M.H.4
Qin, H.J.5
Liu, C.P.6
-
35
-
-
17144374934
-
Regulatory T-cell therapy: is it ready for the clinic?
-
PID: 15775994, COI: 1:CAS:528:DC%2BD2MXivVaku7s%3D
-
Bluestone JA (2005) Regulatory T-cell therapy: is it ready for the clinic? Nat Rev Immunol 5:343–349
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 343-349
-
-
Bluestone, J.A.1
-
36
-
-
38449090623
-
d’Hennezel E, Albanese A, Piccirillo CA. Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes
-
PID: 17928397, COI: 1:CAS:528:DC%2BD1cXmt1Wrtw%3D%3D
-
Tritt M, Sgouroudis E (2008) d’Hennezel E, Albanese A, Piccirillo CA. Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes. Diabetes 57:113–123
-
(2008)
Diabetes
, vol.57
, pp. 113-123
-
-
Tritt, M.1
Sgouroudis, E.2
-
37
-
-
29244482759
-
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
-
PID: 16311599, COI: 1:CAS:528:DC%2BD2MXhtlSqu7rP
-
Tang Q, Adams JY, Tooley AJ, Bi M, Fife BT, Serra P et al (2006) Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice. Nat Immunol 7:83–92
-
(2006)
Nat Immunol
, vol.7
, pp. 83-92
-
-
Tang, Q.1
Adams, J.Y.2
Tooley, A.J.3
Bi, M.4
Fife, B.T.5
Serra, P.6
-
38
-
-
70349755645
-
How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets
-
PID: 19818653, COI: 1:CAS:528:DC%2BD1MXhsVChtLrL
-
Feuerer M, Shen Y, Littman DR, Benoist C, Mathis D (2009) How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. Immunity 31:654–664
-
(2009)
Immunity
, vol.31
, pp. 654-664
-
-
Feuerer, M.1
Shen, Y.2
Littman, D.R.3
Benoist, C.4
Mathis, D.5
-
39
-
-
1242290580
-
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10
-
COI: 1:CAS:528:DC%2BD2cXjt1CksLo%3D
-
Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA (2004) Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. J Immunol (Baltimore, Md: 1950) 172:5213–5221
-
(2004)
J Immunol (Baltimore, Md: 1950)
, vol.172
, pp. 5213-5221
-
-
Zheng, S.G.1
Wang, J.H.2
Gray, J.D.3
Soucier, H.4
Horwitz, D.A.5
-
40
-
-
67650003971
-
Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner
-
PID: 19404982, COI: 1:CAS:528:DC%2BD1MXltlegtrY%3D
-
Tonkin DR, Haskins K (2009) Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner. Eur J Immunol 39:1313–1322
-
(2009)
Eur J Immunol
, vol.39
, pp. 1313-1322
-
-
Tonkin, D.R.1
Haskins, K.2
-
41
-
-
27144495833
-
How do CD4+CD25+ regulatory T cells control autoimmunity?
-
PID: 16209918, COI: 1:CAS:528:DC%2BD2MXhtFKhsb3F
-
Bluestone JA, Tang Q (2005) How do CD4+CD25+ regulatory T cells control autoimmunity? Curr Opin Immunol 17:638–642
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 638-642
-
-
Bluestone, J.A.1
Tang, Q.2
-
42
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
COI: 1:CAS:528:DC%2BD1cXht1Slu7%2FJ
-
Wing K, Onishi Y, Prieto-Martin P, Yamaguchi T, Miyara M, Fehervari Z et al (2008) CTLA-4 control over Foxp3+ regulatory T cell function. Science (New York, NY) 322:271–275
-
(2008)
Science (New York, NY)
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
-
43
-
-
84884704400
-
CTLA-4 and autoimmunity: new insights into the dual regulator of tolerance
-
PID: 23851140, COI: 1:CAS:528:DC%2BC3sXhtFOrsrrP
-
Romo-Tena J, Gomez-Martin D, Alcocer-Varela J (2013) CTLA-4 and autoimmunity: new insights into the dual regulator of tolerance. Autoimmun Rev 12:1171–1176
-
(2013)
Autoimmun Rev
, vol.12
, pp. 1171-1176
-
-
Romo-Tena, J.1
Gomez-Martin, D.2
Alcocer-Varela, J.3
-
44
-
-
77956931125
-
CD4+ CD25+ regulatory T cells prevent type 1 diabetes preceded by dendritic cell-dominant invasive insulitis by affecting chemotaxis and local invasiveness of dendritic cells
-
COI: 1:CAS:528:DC%2BC3cXpslWms7Y%3D
-
Lee MH, Lee WH, Todorov I, Liu CP (2010) CD4+ CD25+ regulatory T cells prevent type 1 diabetes preceded by dendritic cell-dominant invasive insulitis by affecting chemotaxis and local invasiveness of dendritic cells. J Immunol (Baltimore, Md: 1950) 185:2493–2501
-
(2010)
J Immunol (Baltimore, Md: 1950)
, vol.185
, pp. 2493-2501
-
-
Lee, M.H.1
Lee, W.H.2
Todorov, I.3
Liu, C.P.4
-
45
-
-
0035879091
-
Regulation of TGF-beta response during T cell activation is modulated by IL-10
-
COI: 1:CAS:528:DC%2BD3MXotFWktr4%3D
-
Cottrez F, Groux H (2001) Regulation of TGF-beta response during T cell activation is modulated by IL-10. J Immunol (Baltimore, Md: 1950) 167:773–778
-
(2001)
J Immunol (Baltimore, Md: 1950)
, vol.167
, pp. 773-778
-
-
Cottrez, F.1
Groux, H.2
-
46
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
PID: 11244051, COI: 1:CAS:528:DC%2BD3MXivFKgu70%3D
-
Moore KW, de Waal MR, Coffman RL, O’Garra A (2001) Interleukin-10 and the interleukin-10 receptor. Annu Rev Immunol 19:683–765
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
de Waal, M.R.2
Coffman, R.L.3
O’Garra, A.4
-
47
-
-
84856669229
-
IFN-gamma induced by IL-12 administration prevents diabetes by inhibiting pathogenic IL-17 production in NOD mice
-
PID: 22186068, COI: 1:CAS:528:DC%2BC38Xit1aqurg%3D
-
Zhang J, Huang Z, Sun R, Tian Z, Wei H (2012) IFN-gamma induced by IL-12 administration prevents diabetes by inhibiting pathogenic IL-17 production in NOD mice. J Autoimmun 38:20–28
-
(2012)
J Autoimmun
, vol.38
, pp. 20-28
-
-
Zhang, J.1
Huang, Z.2
Sun, R.3
Tian, Z.4
Wei, H.5
-
48
-
-
18844371714
-
Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango
-
PID: 15827965, COI: 1:CAS:528:DC%2BD2MXksVKnsbs%3D
-
Scheffold A, Huhn J, Hofer T (2005) Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL-)two to tango. Eur J Immunol 35:1336–1341
-
(2005)
Eur J Immunol
, vol.35
, pp. 1336-1341
-
-
Scheffold, A.1
Huhn, J.2
Hofer, T.3
-
49
-
-
84881375970
-
Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells
-
PID: 23895744, COI: 1:CAS:528:DC%2BC3sXhtF2iu77F
-
Edwards LJ, Evavold BD (2013) Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells. J Autoimmun 44:82–90
-
(2013)
J Autoimmun
, vol.44
, pp. 82-90
-
-
Edwards, L.J.1
Evavold, B.D.2
-
50
-
-
85057635708
-
Cell trafficking in health and autoimmunity: a comprehensive review
-
Peng H, Tian Z. NK (2013) Cell trafficking in health and autoimmunity: a comprehensive review. Clin Rev Allergy Immunol
-
(2013)
Clin Rev Allergy Immunol
-
-
Peng, H.1
Tian, Z.N.K.2
-
51
-
-
84888197665
-
Recombinant soluble CD137 prevents type one diabetes in nonobese diabetic mice
-
PID: 24145149, COI: 1:CAS:528:DC%2BC3sXhslSlsL7P
-
Kachapati K, Bednar KJ, Adams DE, Wu Y, Mittler RS, Jordan MB et al (2013) Recombinant soluble CD137 prevents type one diabetes in nonobese diabetic mice. J Autoimmun 47:94–103
-
(2013)
J Autoimmun
, vol.47
, pp. 94-103
-
-
Kachapati, K.1
Bednar, K.J.2
Adams, D.E.3
Wu, Y.4
Mittler, R.S.5
Jordan, M.B.6
-
52
-
-
0036141438
-
Multiple immuno-regulatory defects in type-1 diabetes
-
PID: 11781358, COI: 1:CAS:528:DC%2BD38Xjtlartg%3D%3D
-
Kukreja A, Cost G, Marker J, Zhang C, Sun Z, Lin-Su K et al (2002) Multiple immuno-regulatory defects in type-1 diabetes. J Clin Invest 109:131–140
-
(2002)
J Clin Invest
, vol.109
, pp. 131-140
-
-
Kukreja, A.1
Cost, G.2
Marker, J.3
Zhang, C.4
Sun, Z.5
Lin-Su, K.6
-
53
-
-
79959196948
-
Lower frequency of CD62L(high) and higher frequency of TNFR2(+) Tregs are associated with inflammatory conditions in type 1 diabetic patients
-
COI: 1:CAS:528:DC%2BC3MXmtFWhtrg%3D
-
Ryba M, Rybarczyk-Kapturska K, Zorena K, Mysliwiec M, Mysliwska J (2011) Lower frequency of CD62L(high) and higher frequency of TNFR2(+) Tregs are associated with inflammatory conditions in type 1 diabetic patients. Mediat Inflamm 2011:645643
-
(2011)
Mediat Inflamm
, vol.2011
, pp. 645643
-
-
Ryba, M.1
Rybarczyk-Kapturska, K.2
Zorena, K.3
Mysliwiec, M.4
Mysliwska, J.5
-
54
-
-
12144249838
-
Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
-
PID: 15616015, COI: 1:CAS:528:DC%2BD2MXhtVWju74%3D
-
Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, Tree TI (2005) Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes. Diabetes 54:92–99
-
(2005)
Diabetes
, vol.54
, pp. 92-99
-
-
Lindley, S.1
Dayan, C.M.2
Bishop, A.3
Roep, B.O.4
Peakman, M.5
Tree, T.I.6
-
55
-
-
13944270218
-
CD4+CD25high regulatory T cells in human autoimmune diabetes
-
PID: 15725577, COI: 1:CAS:528:DC%2BD2MXhslWltLg%3D
-
Putnam AL, Vendrame F, Dotta F, Gottlieb PA (2005) CD4+CD25high regulatory T cells in human autoimmune diabetes. J Autoimmun 24:55–62
-
(2005)
J Autoimmun
, vol.24
, pp. 55-62
-
-
Putnam, A.L.1
Vendrame, F.2
Dotta, F.3
Gottlieb, P.A.4
-
56
-
-
68249100526
-
Diminished expression of ICOS, GITR and CTLA-4 at the mRNA level in T regulatory cells of children with newly diagnosed type 1 diabetes
-
PID: 19547759, COI: 1:CAS:528:DC%2BD1MXotlert7c%3D
-
Luczynski W, Wawrusiewicz-Kurylonek N, Stasiak-Barmuta A, Urban R, Ilendo E, Urban M et al (2009) Diminished expression of ICOS, GITR and CTLA-4 at the mRNA level in T regulatory cells of children with newly diagnosed type 1 diabetes. Acta Biochim Pol 56:361–370
-
(2009)
Acta Biochim Pol
, vol.56
, pp. 361-370
-
-
Luczynski, W.1
Wawrusiewicz-Kurylonek, N.2
Stasiak-Barmuta, A.3
Urban, R.4
Ilendo, E.5
Urban, M.6
-
57
-
-
55449111318
-
Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes
-
PID: 19037920, COI: 1:CAS:528:DC%2BD1MXjs1Kqsg%3D%3D
-
Lawson JM, Tremble J, Dayan C, Beyan H, Leslie RD, Peakman M et al (2008) Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes. Clin Exp Immunol 154:353–359
-
(2008)
Clin Exp Immunol
, vol.154
, pp. 353-359
-
-
Lawson, J.M.1
Tremble, J.2
Dayan, C.3
Beyan, H.4
Leslie, R.D.5
Peakman, M.6
-
58
-
-
17844364504
-
Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes
-
PID: 15855327, COI: 1:CAS:528:DC%2BD2MXktVCksL0%3D
-
Brusko TM, Wasserfall CH, Clare-Salzler MJ, Schatz DA, Atkinson MA (2005) Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes. Diabetes 54:1407–1414
-
(2005)
Diabetes
, vol.54
, pp. 1407-1414
-
-
Brusko, T.M.1
Wasserfall, C.H.2
Clare-Salzler, M.J.3
Schatz, D.A.4
Atkinson, M.A.5
-
59
-
-
58149188480
-
The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells
-
COI: 1:CAS:528:DC%2BD1cXhtlaisrnF
-
Schneider A, Rieck M, Sanda S, Pihoker C, Greenbaum C, Buckner JH (2008) The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells. J Immunol (Baltimore, Md: 1950) 181:7350–7355
-
(2008)
J Immunol (Baltimore, Md: 1950)
, vol.181
, pp. 7350-7355
-
-
Schneider, A.1
Rieck, M.2
Sanda, S.3
Pihoker, C.4
Greenbaum, C.5
Buckner, J.H.6
-
60
-
-
51849122220
-
Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells
-
PID: 18559659, COI: 1:CAS:528:DC%2BD1cXhtFSrtrjM
-
Monti P, Scirpoli M, Maffi P, Piemonti L, Secchi A, Bonifacio E et al (2008) Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells. Diabetes 57:2341–2347
-
(2008)
Diabetes
, vol.57
, pp. 2341-2347
-
-
Monti, P.1
Scirpoli, M.2
Maffi, P.3
Piemonti, L.4
Secchi, A.5
Bonifacio, E.6
-
61
-
-
34447640430
-
At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction
-
PID: 17206281, COI: 1:CAS:528:DC%2BD2sXjsFemtrk%3D
-
Glisic-Milosavljevic S, Waukau J, Jailwala P, Jana S, Khoo HJ, Albertz H et al (2007) At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction. PLoS One 2:e146
-
(2007)
PLoS One
, vol.2
, pp. e146
-
-
Glisic-Milosavljevic, S.1
Waukau, J.2
Jailwala, P.3
Jana, S.4
Khoo, H.J.5
Albertz, H.6
-
62
-
-
80052841136
-
Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes
-
PID: 21715555, COI: 1:CAS:528:DC%2BC3MXhtValurbE
-
Hughson A, Bromberg I, Johnson B, Quataert S, Jospe N, Fowell DJ (2011) Uncoupling of proliferation and cytokines from suppression within the CD4+CD25+Foxp3+ T-cell compartment in the 1st year of human type 1 diabetes. Diabetes 60:2125–2133
-
(2011)
Diabetes
, vol.60
, pp. 2125-2133
-
-
Hughson, A.1
Bromberg, I.2
Johnson, B.3
Quataert, S.4
Jospe, N.5
Fowell, D.J.6
-
63
-
-
77949265942
-
Inducible regulatory T cells (iTregs) from recent-onset type 1 diabetes subjects show increased in vitro suppression and higher ITCH levels compared with controls
-
PID: 20143240, COI: 1:CAS:528:DC%2BC3cXis1yjs70%3D
-
Glisic S, Ehlenbach S, Jailwala P, Waukau J, Jana S, Ghosh S (2010) Inducible regulatory T cells (iTregs) from recent-onset type 1 diabetes subjects show increased in vitro suppression and higher ITCH levels compared with controls. Cell Tissue Res 339:585–595
-
(2010)
Cell Tissue Res
, vol.339
, pp. 585-595
-
-
Glisic, S.1
Ehlenbach, S.2
Jailwala, P.3
Waukau, J.4
Jana, S.5
Ghosh, S.6
-
64
-
-
84931749041
-
The serum IL-6 profile and Treg/Th17 peripheral cell populations in patients with type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXjslCns7o%3D
-
Ryba-Stanislawowska M, Skrzypkowska M, Mysliwska J, Mysliwiec M (2013) The serum IL-6 profile and Treg/Th17 peripheral cell populations in patients with type 1 diabetes. Mediat Inflamm 2013:205284
-
(2013)
Mediat Inflamm
, vol.2013
, pp. 205284
-
-
Ryba-Stanislawowska, M.1
Skrzypkowska, M.2
Mysliwska, J.3
Mysliwiec, M.4
-
65
-
-
79955028001
-
Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3MXjvVKmt7Y%3D
-
McClymont SA, Putnam AL, Lee MR, Esensten JH, Liu W, Hulme MA et al (2011) Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. J Immunol (Baltimore, Md: 1950) 186:3918–3926
-
(2011)
J Immunol (Baltimore, Md: 1950)
, vol.186
, pp. 3918-3926
-
-
McClymont, S.A.1
Putnam, A.L.2
Lee, M.R.3
Esensten, J.H.4
Liu, W.5
Hulme, M.A.6
-
66
-
-
84873689748
-
Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals
-
PID: 23409157, COI: 1:CAS:528:DC%2BC3sXjtFKgt74%3D
-
Du W, Shen YW, Lee WH, Wang D, Paz S, Kandeel F et al (2013) Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals. PLoS One 8:e56209
-
(2013)
PLoS One
, vol.8
, pp. e56209
-
-
Du, W.1
Shen, Y.W.2
Lee, W.H.3
Wang, D.4
Paz, S.5
Kandeel, F.6
-
67
-
-
33847373481
-
No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
-
PID: 17327427, COI: 1:CAS:528:DC%2BD2sXis12itrg%3D
-
Brusko T, Wasserfall C, McGrail K, Schatz R, Viener HL, Schatz D et al (2007) No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes. Diabetes 56:604–612
-
(2007)
Diabetes
, vol.56
, pp. 604-612
-
-
Brusko, T.1
Wasserfall, C.2
McGrail, K.3
Schatz, R.4
Viener, H.L.5
Schatz, D.6
-
68
-
-
77958136352
-
Cutting edge: increased IL-17-secreting T cells in children with new-onset type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3cXhtFyisrrN
-
Marwaha AK, Crome SQ, Panagiotopoulos C, Berg KB, Qin H, Ouyang Q et al (2010) Cutting edge: increased IL-17-secreting T cells in children with new-onset type 1 diabetes. J Immunol (Baltimore, Md: 1950) 185:3814–3818
-
(2010)
J Immunol (Baltimore, Md: 1950)
, vol.185
, pp. 3814-3818
-
-
Marwaha, A.K.1
Crome, S.Q.2
Panagiotopoulos, C.3
Berg, K.B.4
Qin, H.5
Ouyang, Q.6
-
69
-
-
70149107014
-
Regulatory T cells in type 1 diabetic patients with autoimmune chronic atrophic gastritis
-
PID: 19291424, COI: 1:CAS:528:DC%2BD1MXpsVGjtrY%3D
-
Alonso N, Martinez-Arconada MJ, Granada ML, Soldevila B, Canton A, Mate JL et al (2009) Regulatory T cells in type 1 diabetic patients with autoimmune chronic atrophic gastritis. Endocrine 35:420–428
-
(2009)
Endocrine
, vol.35
, pp. 420-428
-
-
Alonso, N.1
Martinez-Arconada, M.J.2
Granada, M.L.3
Soldevila, B.4
Canton, A.5
Mate, J.L.6
-
70
-
-
84880033192
-
CD4(+) CD45RA(-) FoxP3high activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes
-
PID: 23607886, COI: 1:CAS:528:DC%2BC3sXhtVKrs7fJ
-
Haseda F, Imagawa A, Murase-Mishiba Y, Terasaki J, Hanafusa T (2013) CD4(+) CD45RA(-) FoxP3high activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes. Clin Exp Immunol 173:207–216
-
(2013)
Clin Exp Immunol
, vol.173
, pp. 207-216
-
-
Haseda, F.1
Imagawa, A.2
Murase-Mishiba, Y.3
Terasaki, J.4
Hanafusa, T.5
-
71
-
-
80052829380
-
Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes
-
PID: 21646390, COI: 1:CAS:528:DC%2BC3MXhtValurbJ
-
Badami E, Sorini C, Coccia M, Usuelli V, Molteni L, Bolla AM et al (2011) Defective differentiation of regulatory FoxP3+ T cells by small-intestinal dendritic cells in patients with type 1 diabetes. Diabetes 60:2120–2124
-
(2011)
Diabetes
, vol.60
, pp. 2120-2124
-
-
Badami, E.1
Sorini, C.2
Coccia, M.3
Usuelli, V.4
Molteni, L.5
Bolla, A.M.6
-
72
-
-
80755148666
-
Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes
-
PID: 21896932, COI: 1:CAS:528:DC%2BC3MXhsVyis77P
-
Ferraro A, Socci C, Stabilini A, Valle A, Monti P, Piemonti L et al (2011) Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes. Diabetes 60:2903–2913
-
(2011)
Diabetes
, vol.60
, pp. 2903-2913
-
-
Ferraro, A.1
Socci, C.2
Stabilini, A.3
Valle, A.4
Monti, P.5
Piemonti, L.6
-
73
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
-
PID: 16818678, COI: 1:CAS:528:DC%2BD28XntVCgs70%3D
-
Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S et al (2006) CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J Exp Med 203:1701–1711
-
(2006)
J Exp Med
, vol.203
, pp. 1701-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
-
74
-
-
60549115770
-
Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
-
PID: 19174509, COI: 1:CAS:528:DC%2BD1MXitV2is7g%3D
-
Komatsu N, Mariotti-Ferrandiz ME, Wang Y, Malissen B, Waldmann H, Hori S (2009) Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity. Proc Natl Acad Sci U S A 106:1903–1908
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1903-1908
-
-
Komatsu, N.1
Mariotti-Ferrandiz, M.E.2
Wang, Y.3
Malissen, B.4
Waldmann, H.5
Hori, S.6
-
75
-
-
46749138596
-
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
-
PID: 18585065, COI: 1:CAS:528:DC%2BD1cXptF2mtLo%3D
-
Yang XO, Nurieva R, Martinez GJ, Kang HS, Chung Y, Pappu BP et al (2008) Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 29:44–56
-
(2008)
Immunity
, vol.29
, pp. 44-56
-
-
Yang, X.O.1
Nurieva, R.2
Martinez, G.J.3
Kang, H.S.4
Chung, Y.5
Pappu, B.P.6
-
76
-
-
77449143100
-
Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects
-
PID: 19875613, COI: 1:CAS:528:DC%2BC3cXhvVyru74%3D
-
Long SA, Cerosaletti K, Bollyky PL, Tatum M, Shilling H, Zhang S et al (2010) Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects. Diabetes 59:407–415
-
(2010)
Diabetes
, vol.59
, pp. 407-415
-
-
Long, S.A.1
Cerosaletti, K.2
Bollyky, P.L.3
Tatum, M.4
Shilling, H.5
Zhang, S.6
-
77
-
-
58149299735
-
Analysis of islet inflammation in human type 1 diabetes
-
PID: 19128359, COI: 1:STN:280:DC%2BD1M%2FlslKltw%3D%3D
-
Willcox A, Richardson SJ, Bone AJ, Foulis AK, Morgan NG (2009) Analysis of islet inflammation in human type 1 diabetes. Clin Exp Immunol 155:173–181
-
(2009)
Clin Exp Immunol
, vol.155
, pp. 173-181
-
-
Willcox, A.1
Richardson, S.J.2
Bone, A.J.3
Foulis, A.K.4
Morgan, N.G.5
-
78
-
-
84868591487
-
Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and beta cell regeneration in a T1D model
-
PID: 23042535, COI: 1:CAS:528:DC%2BC38Xhs1arsb3O
-
Nti BK, Markman JL, Bertera S, Styche AJ, Lakomy RJ, Subbotin VM et al (2012) Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and beta cell regeneration in a T1D model. Cell Mol Immunol 9:455–463
-
(2012)
Cell Mol Immunol
, vol.9
, pp. 455-463
-
-
Nti, B.K.1
Markman, J.L.2
Bertera, S.3
Styche, A.J.4
Lakomy, R.J.5
Subbotin, V.M.6
-
79
-
-
0036196305
-
Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals
-
PID: 11869680, COI: 1:CAS:528:DC%2BD38XitVCju7c%3D
-
Green EA, Choi Y, Flavell RA (2002) Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity 16:183–191
-
(2002)
Immunity
, vol.16
, pp. 183-191
-
-
Green, E.A.1
Choi, Y.2
Flavell, R.A.3
-
80
-
-
79960983261
-
Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets
-
PID: 21737880, COI: 1:CAS:528:DC%2BC3MXhtVejurzE
-
Montane J, Bischoff L, Soukhatcheva G, Dai DL, Hardenberg G, Levings MK et al (2011) Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets. J Clin Invest 121:3024–3028
-
(2011)
J Clin Invest
, vol.121
, pp. 3024-3028
-
-
Montane, J.1
Bischoff, L.2
Soukhatcheva, G.3
Dai, D.L.4
Hardenberg, G.5
Levings, M.K.6
-
81
-
-
84899494386
-
Plasmacytoid dendritic cells license regulatory T cells, upon iNKT-cell stimulation, to prevent autoimmune diabetes
-
Beaudoin L, Diana J, Ghazarian L, Simoni Y, Boitard C, Lehuen A. (2014) Plasmacytoid dendritic cells license regulatory T cells, upon iNKT-cell stimulation, to prevent autoimmune diabetes. European journal of immunology
-
(2014)
European journal of immunology
-
-
Beaudoin, L.1
Diana, J.2
Ghazarian, L.3
Simoni, Y.4
Boitard, C.5
Lehuen, A.6
-
82
-
-
33847301982
-
Dendritic cells with TGF-beta1 differentiate naive CD4+CD25− T cells into islet-protective Foxp3+ regulatory T cells
-
PID: 17307871, COI: 1:CAS:528:DC%2BD1cXkvFalu7Y%3D
-
Luo X, Tarbell KV, Yang H, Pothoven K, Bailey SL, Ding R et al (2007) Dendritic cells with TGF-beta1 differentiate naive CD4+CD25− T cells into islet-protective Foxp3+ regulatory T cells. Proc Natl Acad Sci U S A 104:2821–2826
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 2821-2826
-
-
Luo, X.1
Tarbell, K.V.2
Yang, H.3
Pothoven, K.4
Bailey, S.L.5
Ding, R.6
-
83
-
-
33846410255
-
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
-
PID: 17210729, COI: 1:CAS:528:DC%2BD2sXhtFGjt70%3D
-
Tarbell KV, Petit L, Zuo X, Toy P, Luo X, Mqadmi A et al (2007) Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J Exp Med 204:191–201
-
(2007)
J Exp Med
, vol.204
, pp. 191-201
-
-
Tarbell, K.V.1
Petit, L.2
Zuo, X.3
Toy, P.4
Luo, X.5
Mqadmi, A.6
-
84
-
-
84873724732
-
NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes
-
PID: 22944096, COI: 1:CAS:528:DC%2BC38XhtlSgtLvO
-
Van Belle TL, Ling E, Haase C, Bresson D, Urso B, von Herrath MG (2013) NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes. J Autoimmun 40:66–73
-
(2013)
J Autoimmun
, vol.40
, pp. 66-73
-
-
Van Belle, T.L.1
Ling, E.2
Haase, C.3
Bresson, D.4
Urso, B.5
von Herrath, M.G.6
-
85
-
-
77952243765
-
Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy
-
PID: 19931408, COI: 1:CAS:528:DC%2BC3cXltF2msbw%3D
-
Orban T, Farkas K, Jalahej H, Kis J, Treszl A, Falk B et al (2010) Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy. J Autoimmun 34:408–415
-
(2010)
J Autoimmun
, vol.34
, pp. 408-415
-
-
Orban, T.1
Farkas, K.2
Jalahej, H.3
Kis, J.4
Treszl, A.5
Falk, B.6
-
86
-
-
78651374710
-
GAD-alum treatment induces GAD65-specific CD4+CD25highFOXP3+ cells in type 1 diabetic patients
-
COI: 1:CAS:528:DC%2BC3MXnsVansQ%3D%3D
-
Hjorth M, Axelsson S, Ryden A, Faresjo M, Ludvigsson J, Casas R (2011) GAD-alum treatment induces GAD65-specific CD4+CD25highFOXP3+ cells in type 1 diabetic patients. Clin Immunol (Orlando, Fla) 138:117–126
-
(2011)
Clin Immunol (Orlando, Fla)
, vol.138
, pp. 117-126
-
-
Hjorth, M.1
Axelsson, S.2
Ryden, A.3
Faresjo, M.4
Ludvigsson, J.5
Casas, R.6
-
87
-
-
20044375937
-
A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
-
PID: 15919798, COI: 1:CAS:528:DC%2BD2MXltVait7o%3D
-
Herold KC, Gitelman SE, Masharani U, Hagopian W, Bisikirska B, Donaldson D et al (2005) A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54:1763–1769
-
(2005)
Diabetes
, vol.54
, pp. 1763-1769
-
-
Herold, K.C.1
Gitelman, S.E.2
Masharani, U.3
Hagopian, W.4
Bisikirska, B.5
Donaldson, D.6
-
88
-
-
20544443927
-
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
-
PID: 15972866, COI: 1:CAS:528:DC%2BD2MXls1Wqu7k%3D
-
Keymeulen B, Vandemeulebroucke E, Ziegler AG, Mathieu C, Kaufman L, Hale G et al (2005) Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 352:2598–2608
-
(2005)
N Engl J Med
, vol.352
, pp. 2598-2608
-
-
Keymeulen, B.1
Vandemeulebroucke, E.2
Ziegler, A.G.3
Mathieu, C.4
Kaufman, L.5
Hale, G.6
-
89
-
-
55249110198
-
GAD treatment and insulin secretion in recent-onset type 1 diabetes
-
PID: 18843118, COI: 1:CAS:528:DC%2BD1cXhtlaitbbF
-
Ludvigsson J, Faresjo M, Hjorth M, Axelsson S, Cheramy M, Pihl M et al (2008) GAD treatment and insulin secretion in recent-onset type 1 diabetes. N Engl J Med 359:1909–1920
-
(2008)
N Engl J Med
, vol.359
, pp. 1909-1920
-
-
Ludvigsson, J.1
Faresjo, M.2
Hjorth, M.3
Axelsson, S.4
Cheramy, M.5
Pihl, M.6
-
90
-
-
83155164619
-
Long-lasting immune responses 4 years after GAD-alum treatment in children with type 1 diabetes
-
PID: 22174945, COI: 1:CAS:528:DC%2BC38XoslOj
-
Axelsson S, Cheramy M, Hjorth M, Pihl M, Akerman L, Martinuzzi E et al (2011) Long-lasting immune responses 4 years after GAD-alum treatment in children with type 1 diabetes. PLoS One 6:e29008
-
(2011)
PLoS One
, vol.6
, pp. e29008
-
-
Axelsson, S.1
Cheramy, M.2
Hjorth, M.3
Pihl, M.4
Akerman, L.5
Martinuzzi, E.6
-
91
-
-
64749084427
-
C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BD1MXksVyksLY%3D
-
Couri CE, Oliveira MC, Stracieri AB, Moraes DA, Pieroni F, Barros GM et al (2009) C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA: J Am Med Assoc 301:1573–1579
-
(2009)
JAMA : J Am Med Assoc
, vol.301
, pp. 1573-1579
-
-
Couri, C.E.1
Oliveira, M.C.2
Stracieri, A.B.3
Moraes, D.A.4
Pieroni, F.5
Barros, G.M.6
-
92
-
-
34247154341
-
Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BD2sXktFeitL0%3D
-
Voltarelli JC, Couri CE, Stracieri AB, Oliveira MC, Moraes DA, Pieroni F et al (2007) Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA: J Am Med Assoc 297:1568–1576
-
(2007)
JAMA : J Am Med Assoc
, vol.297
, pp. 1568-1576
-
-
Voltarelli, J.C.1
Couri, C.E.2
Stracieri, A.B.3
Oliveira, M.C.4
Moraes, D.A.5
Pieroni, F.6
-
93
-
-
84857841147
-
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide
-
PID: 22011412, COI: 1:CAS:528:DC%2BC38XhtVaqsA%3D%3D
-
Haller MJ, Wasserfall CH, Hulme MA, Cintron M, Brusko TM, McGrail KM et al (2011) Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide. Diabetes Care 34:2567–2569
-
(2011)
Diabetes Care
, vol.34
, pp. 2567-2569
-
-
Haller, M.J.1
Wasserfall, C.H.2
Hulme, M.A.3
Cintron, M.4
Brusko, T.M.5
McGrail, K.M.6
-
94
-
-
84879395767
-
Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes
-
COI: 1:CAS:528:DC%2BC3sXpvVynsLg%3D
-
Haller MJ, Wasserfall CH, Hulme MA, Cintron M, Brusko TM, McGrail KM et al (2013) Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes. Biol Blood Marrow Transplant: J Am Soc Blood Marrow Transplant 19:1126–1129
-
(2013)
Biol Blood Marrow Transplant : J Am Soc Blood Marrow Transplant
, vol.19
, pp. 1126-1129
-
-
Haller, M.J.1
Wasserfall, C.H.2
Hulme, M.A.3
Cintron, M.4
Brusko, T.M.5
McGrail, K.M.6
-
95
-
-
84896401653
-
Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: a non-randomized, controlled trial
-
PID: 24102806, COI: 1:CAS:528:DC%2BC2cXkslCkurs%3D
-
Giannopoulou EZ, Puff R, Beyerlein A, von Luettichau I, Boerschmann H, Schatz D et al (2014) Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: a non-randomized, controlled trial. Pediatr Diabetes 15:100–109
-
(2014)
Pediatr Diabetes
, vol.15
, pp. 100-109
-
-
Giannopoulou, E.Z.1
Puff, R.2
Beyerlein, A.3
von Luettichau, I.4
Boerschmann, H.5
Schatz, D.6
-
96
-
-
84855491166
-
Reversal of type 1 diabetes via islet beta cell regeneration following immune modulation by cord blood-derived multipotent stem cells
-
PID: 22233865, COI: 1:CAS:528:DC%2BC38Xkslantr8%3D
-
Zhao Y, Jiang Z, Zhao T, Ye M, Hu C, Yin Z et al (2012) Reversal of type 1 diabetes via islet beta cell regeneration following immune modulation by cord blood-derived multipotent stem cells. BMC Med 10:3
-
(2012)
BMC Med
, vol.10
, pp. 3
-
-
Zhao, Y.1
Jiang, Z.2
Zhao, T.3
Ye, M.4
Hu, C.5
Yin, Z.6
-
97
-
-
34547563816
-
Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody
-
PID: 17456848, COI: 1:CAS:528:DC%2BD2sXos12qsLs%3D
-
Ishikawa H, Ochi H, Chen ML, Frenkel D, Maron R, Weiner HL (2007) Inhibition of autoimmune diabetes by oral administration of anti-CD3 monoclonal antibody. Diabetes 56:2103–2109
-
(2007)
Diabetes
, vol.56
, pp. 2103-2109
-
-
Ishikawa, H.1
Ochi, H.2
Chen, M.L.3
Frenkel, D.4
Maron, R.5
Weiner, H.L.6
-
98
-
-
0031569177
-
CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
-
COI: 1:CAS:528:DyaK2sXhvVOltro%3D
-
Chatenoud L, Primo J, Bach JF (1997) CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J Immunol (Baltimore, Md: 1950) 158:2947–2954
-
(1997)
J Immunol (Baltimore, Md: 1950)
, vol.158
, pp. 2947-2954
-
-
Chatenoud, L.1
Primo, J.2
Bach, J.F.3
-
99
-
-
84887025288
-
Anti-CD3 clinical trials in type 1 diabetes mellitus
-
COI: 1:CAS:528:DC%2BC3sXosVGmsr8%3D
-
Daifotis AG, Koenig S, Chatenoud L, Herold KC (2013) Anti-CD3 clinical trials in type 1 diabetes mellitus. Clin Immunol (Orlando, Fla) 149:268–278
-
(2013)
Clin Immunol (Orlando, Fla)
, vol.149
, pp. 268-278
-
-
Daifotis, A.G.1
Koenig, S.2
Chatenoud, L.3
Herold, K.C.4
-
100
-
-
84887052291
-
Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders
-
PID: 23835333, COI: 1:CAS:528:DC%2BC3sXhsleisr7J
-
Herold KC, Gitelman SE, Ehlers MR, Gottlieb PA, Greenbaum CJ, Hagopian W et al (2013) Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders. Diabetes 62:3766–3774
-
(2013)
Diabetes
, vol.62
, pp. 3766-3774
-
-
Herold, K.C.1
Gitelman, S.E.2
Ehlers, M.R.3
Gottlieb, P.A.4
Greenbaum, C.J.5
Hagopian, W.6
-
101
-
-
77949266510
-
Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass
-
PID: 20225393, COI: 1:CAS:528:DC%2BC3cXis1Cmu70%3D
-
Keymeulen B, Walter M, Mathieu C, Kaufman L, Gorus F, Hilbrands R et al (2010) Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass. Diabetologia 53:614–623
-
(2010)
Diabetologia
, vol.53
, pp. 614-623
-
-
Keymeulen, B.1
Walter, M.2
Mathieu, C.3
Kaufman, L.4
Gorus, F.5
Hilbrands, R.6
-
102
-
-
84856564903
-
GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus
-
PID: 22296077, COI: 1:CAS:528:DC%2BC38XitVSjsr4%3D
-
Ludvigsson J, Krisky D, Casas R, Battelino T, Castano L, Greening J et al (2012) GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus. N Engl J Med 366:433–442
-
(2012)
N Engl J Med
, vol.366
, pp. 433-442
-
-
Ludvigsson, J.1
Krisky, D.2
Casas, R.3
Battelino, T.4
Castano, L.5
Greening, J.6
-
103
-
-
79960743608
-
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial
-
PID: 21714999, COI: 1:CAS:528:DC%2BC3MXpt1Ons7c%3D
-
Wherrett DK, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R et al (2011) Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial. Lancet 378:319–327
-
(2011)
Lancet
, vol.378
, pp. 319-327
-
-
Wherrett, D.K.1
Bundy, B.2
Becker, D.J.3
DiMeglio, L.A.4
Gitelman, S.E.5
Goland, R.6
-
104
-
-
17444437590
-
Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabete Insuline Orale group
-
PID: 10950231, COI: 1:CAS:528:DC%2BD3cXmtVCnuro%3D
-
Chaillous L, Lefevre H, Thivolet C, Boitard C, Lahlou N, Atlan-Gepner C et al (2000) Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabete Insuline Orale group. Lancet 356:545–549
-
(2000)
Lancet
, vol.356
, pp. 545-549
-
-
Chaillous, L.1
Lefevre, H.2
Thivolet, C.3
Boitard, C.4
Lahlou, N.5
Atlan-Gepner, C.6
-
105
-
-
20044362563
-
Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes
-
PID: 15681764, COI: 1:CAS:528:DC%2BD2MXislWisbY%3D
-
Ergun-Longmire B, Marker J, Zeidler A, Rapaport R, Raskin P, Bode B et al (2004) Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes. Ann N Y Acad Sci 1029:260–277
-
(2004)
Ann N Y Acad Sci
, vol.1029
, pp. 260-277
-
-
Ergun-Longmire, B.1
Marker, J.2
Zeidler, A.3
Rapaport, R.4
Raskin, P.5
Bode, B.6
-
106
-
-
43349090939
-
Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical type I diabetes
-
PID: 18422727, COI: 1:CAS:528:DC%2BD1cXnvVOitb0%3D
-
Huurman VA, van der Meide PE, Duinkerken G, Willemen S, Cohen IR, Elias D et al (2008) Immunological efficacy of heat shock protein 60 peptide DiaPep277 therapy in clinical type I diabetes. Clin Exp Immunol 152:488–497
-
(2008)
Clin Exp Immunol
, vol.152
, pp. 488-497
-
-
Huurman, V.A.1
van der Meide, P.E.2
Duinkerken, G.3
Willemen, S.4
Cohen, I.R.5
Elias, D.6
-
107
-
-
84888204600
-
Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope
-
PID: 24090977, COI: 1:CAS:528:DC%2BC3sXhsFCit7%2FI
-
Dahan R, Gebe JA, Preisinger A, James EA, Tendler M, Nepom GT et al (2013) Antigen-specific immunomodulation for type 1 diabetes by novel recombinant antibodies directed against diabetes-associates auto-reactive T cell epitope. J Autoimmun 47:83–93
-
(2013)
J Autoimmun
, vol.47
, pp. 83-93
-
-
Dahan, R.1
Gebe, J.A.2
Preisinger, A.3
James, E.A.4
Tendler, M.5
Nepom, G.T.6
-
108
-
-
64149099299
-
Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice
-
PID: 19156219, COI: 1:CAS:528:DC%2BD1MXhsF2ntro%3D
-
Zhao Y, Lin B, Darflinger R, Zhang Y, Holterman MJ, Skidgel RA (2009) Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) mice. PLoS One 4:e4226
-
(2009)
PLoS One
, vol.4
, pp. e4226
-
-
Zhao, Y.1
Lin, B.2
Darflinger, R.3
Zhang, Y.4
Holterman, M.J.5
Skidgel, R.A.6
-
109
-
-
84885898828
-
Early immunotherapy using autologous adult stem cells reversed the effect of anti-pancreatic islets in recently diagnosed type 1 diabetes mellitus: preliminary results
-
Mesples A, Majeed N, Zhang Y, Hu X (2013) Early immunotherapy using autologous adult stem cells reversed the effect of anti-pancreatic islets in recently diagnosed type 1 diabetes mellitus: preliminary results. Med Sci Monit:Int Med J Exp Clin Res 19:852–857
-
(2013)
Med Sci Monit:Int Med J Exp Clin Res
, vol.19
, pp. 852-857
-
-
Mesples, A.1
Majeed, N.2
Zhang, Y.3
Hu, X.4
-
110
-
-
84896116224
-
Efficacy and safety of low-dose otelixizumab anti-CD3 monoclonal antibody in preserving C-peptide secretion in adolescent type 1 diabetes: DEFEND-2, a randomized, placebo-controlled, double-blind, multi-centre study
-
COI: 1:CAS:528:DC%2BC2cXktlCgtL8%3D
-
Ambery P, Donner TW, Biswas N, Donaldson J, Parkin J, Dayan CM (2014) Efficacy and safety of low-dose otelixizumab anti-CD3 monoclonal antibody in preserving C-peptide secretion in adolescent type 1 diabetes: DEFEND-2, a randomized, placebo-controlled, double-blind, multi-centre study. DiabetMed:J Br Diabet Assoc 31:399–402
-
(2014)
DiabetMed:J Br Diabet Assoc
, vol.31
, pp. 399-402
-
-
Ambery, P.1
Donner, T.W.2
Biswas, N.3
Donaldson, J.4
Parkin, J.5
Dayan, C.M.6
-
111
-
-
34249820806
-
Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed type 1 diabetes: a randomised, double-blind phase II study
-
PID: 17124721, COI: 1:CAS:528:DC%2BD2sXntVynur4%3D
-
Lazar L, Ofan R, Weintrob N, Avron A, Tamir M, Elias D et al (2007) Heat-shock protein peptide DiaPep277 treatment in children with newly diagnosed type 1 diabetes: a randomised, double-blind phase II study. Diabetes Metab Res Rev 23:286–291
-
(2007)
Diabetes Metab Res Rev
, vol.23
, pp. 286-291
-
-
Lazar, L.1
Ofan, R.2
Weintrob, N.3
Avron, A.4
Tamir, M.5
Elias, D.6
-
112
-
-
80755168854
-
C-peptide response and HLA genotypes in subjects with recent-onset type 1 diabetes after immunotherapy with DiaPep277: an exploratory study
-
PID: 21896927, COI: 1:CAS:528:DC%2BC3MXhsVyis7%2FF
-
Buzzetti R, Cernea S, Petrone A, Capizzi M, Spoletini M, Zampetti S et al (2011) C-peptide response and HLA genotypes in subjects with recent-onset type 1 diabetes after immunotherapy with DiaPep277: an exploratory study. Diabetes 60:3067–3072
-
(2011)
Diabetes
, vol.60
, pp. 3067-3072
-
-
Buzzetti, R.1
Cernea, S.2
Petrone, A.3
Capizzi, M.4
Spoletini, M.5
Zampetti, S.6
-
113
-
-
84862835868
-
Diabetic ketoacidosis at diagnosis influences complete remission after treatment with hematopoietic stem cell transplantation in adolescents with type 1 diabetes
-
PID: 22723579, COI: 1:CAS:528:DC%2BC38Xht1Sht7rJ
-
Gu W, Hu J, Wang W, Li L, Tang W, Sun S et al (2012) Diabetic ketoacidosis at diagnosis influences complete remission after treatment with hematopoietic stem cell transplantation in adolescents with type 1 diabetes. Diabetes Care 35:1413–1419
-
(2012)
Diabetes Care
, vol.35
, pp. 1413-1419
-
-
Gu, W.1
Hu, J.2
Wang, W.3
Li, L.4
Tang, W.5
Sun, S.6
|