Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes

Diabetes

Volumn 60, Issue 11, 2011, Pages 2903-2913

  Ferraro, Alessandra ^a,b,c   Socci, Carlo ^a   Stabilini, Angela ^a,b   Valle, Andrea ^a,b   Monti, Paolo ^d   Piemonti, Lorenzo ^a   Nano, Rita ^a   Olek, Sven ^e   Maffi, Paola ^a   Scavini, Marina ^a   Secchi, Antonio ^a,c   Staudacher, Carlo ^a,c   Bonifacio, Ezio ^d   Battaglia, Manuela ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^d CENTER FOR REGENERATIVE THERAPIES DRESDEN   (Germany)

^e EPIONTIS GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

ADULT; ARTICLE; CD25+ T LYMPHOCYTE; CELL EXPANSION; CELL ISOLATION; CLINICAL ARTICLE; CONTROLLED STUDY; EPIGENETICS; FEMALE; GENE LOCUS; HUMAN; HUMAN CELL; IMMUNE STATUS; INSULIN DEPENDENT DIABETES MELLITUS; LYMPH NODE; MALE; PANCREAS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH17 CELL; UPREGULATION;

ADULT; AUTOIMMUNITY; CELL COUNT; DIABETES MELLITUS, TYPE 1; DNA METHYLATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GENETIC LOCI; HUMANS; IMMUNITY, CELLULAR; LYMPH NODES; MALE; MIDDLE AGED; PANCREAS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; YOUNG ADULT;

EID: 80755148666     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0090     Document Type: Article

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