메뉴 건너뛰기




Volumn 44, Issue 5, 2014, Pages 1454-1466

Plasmacytoid dendritic cells license regulatory T cells, upon iNKT-cell stimulation, to prevent autoimmune diabetes

Author keywords

Diabetes; NKT; NOD; Plasmacytoid dendritic cells; Regulatory T (Treg) cells

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; CD103 ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR3; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GAMMA INTERFERON; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; PROINSULIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

EID: 84899494386     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343910     Document Type: Article
Times cited : (31)

References (47)
  • 2
    • 84872053925 scopus 로고    scopus 로고
    • Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
    • Diana, J., Simoni, Y., Furio, L., Beaudoin, L., Agerberth, B., Barrat, F. and Lehuen, A., Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes. Nat. Med. 2013. 19: 65-73.
    • (2013) Nat. Med. , vol.19 , pp. 65-73
    • Diana, J.1    Simoni, Y.2    Furio, L.3    Beaudoin, L.4    Agerberth, B.5    Barrat, F.6    Lehuen, A.7
  • 3
    • 77951921063 scopus 로고    scopus 로고
    • Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis
    • Husebye, E. S. and Anderson, M. S., Autoimmune polyendocrine syndromes: clues to type 1 diabetes pathogenesis. Immunity 2010. 32: 479-487.
    • (2010) Immunity , vol.32 , pp. 479-487
    • Husebye, E.S.1    Anderson, M.S.2
  • 4
    • 39449126502 scopus 로고    scopus 로고
    • 3+ regulatory T cell: a jack of all trades, master of regulation
    • 3+ regulatory T cell: a jack of all trades, master of regulation. Nat. Immunol. 2008. 9: 239-244.
    • (2008) Nat. Immunol. , vol.9 , pp. 239-244
    • Tang, Q.1    Bluestone, J.A.2
  • 5
    • 84870424721 scopus 로고    scopus 로고
    • Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality?
    • Simoni, Y., Diana, J., Ghazarian, L., Beaudoin, L. and Lehuen, A., Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality? Clin. Exp. Immunol. 2013. 171: 8-19.
    • (2013) Clin. Exp. Immunol. , vol.171 , pp. 8-19
    • Simoni, Y.1    Diana, J.2    Ghazarian, L.3    Beaudoin, L.4    Lehuen, A.5
  • 6
    • 73249140727 scopus 로고    scopus 로고
    • NKT cells: friend or foe during viral infections?
    • Diana, J. and Lehuen, A., NKT cells: friend or foe during viral infections? Eur. J. Immunol. 2009. 39: 3283-3291.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 3283-3291
    • Diana, J.1    Lehuen, A.2
  • 7
    • 79955738789 scopus 로고    scopus 로고
    • Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay
    • Diana, J., Brezar, V., Beaudoin, L., Dalod, M., Mellor, A., Tafuri, A., von Herrath, M. et al., Viral infection prevents diabetes by inducing regulatory T cells through NKT cell-plasmacytoid dendritic cell interplay. J. Exp. Med. 2011. 208: 729-745.
    • (2011) J. Exp. Med. , vol.208 , pp. 729-745
    • Diana, J.1    Brezar, V.2    Beaudoin, L.3    Dalod, M.4    Mellor, A.5    Tafuri, A.6    von Herrath, M.7
  • 8
    • 0032489860 scopus 로고    scopus 로고
    • Alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10
    • Hammond, K. J., Poulton, L. D., Palmisano, L. J., Silveira, P. A., Godfrey, D. I. and Baxter, A. G., Alpha/beta-T cell receptor (TCR)+CD4-CD8- (NKT) thymocytes prevent insulin-dependent diabetes mellitus in nonobese diabetic (NOD)/Lt mice by the influence of interleukin (IL)-4 and/or IL-10. J. Exp. Med. 1998. 187: 1047-1056.
    • (1998) J. Exp. Med. , vol.187 , pp. 1047-1056
    • Hammond, K.J.1    Poulton, L.D.2    Palmisano, L.J.3    Silveira, P.A.4    Godfrey, D.I.5    Baxter, A.G.6
  • 9
    • 0032538904 scopus 로고    scopus 로고
    • Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes
    • Lehuen, A., Lantz, O., Beaudoin, L., Laloux, V., Carnaud, C., Bendelac, A., Bach, J. F. et al., Overexpression of natural killer T cells protects Valpha14- Jalpha281 transgenic nonobese diabetic mice against diabetes. J. Exp. Med. 1998. 188: 1831-1839.
    • (1998) J. Exp. Med. , vol.188 , pp. 1831-1839
    • Lehuen, A.1    Lantz, O.2    Beaudoin, L.3    Laloux, V.4    Carnaud, C.5    Bendelac, A.6    Bach, J.F.7
  • 10
    • 0034799397 scopus 로고    scopus 로고
    • Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes
    • Sharif, S., Arreaza, G. A., Zucker, P., Mi, Q. S., Sondhi, J., Naidenko, O. V., Kronenberg, M. et al., Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes. Nat. Med. 2001. 7: 1057-1062.
    • (2001) Nat. Med. , vol.7 , pp. 1057-1062
    • Sharif, S.1    Arreaza, G.A.2    Zucker, P.3    Mi, Q.S.4    Sondhi, J.5    Naidenko, O.V.6    Kronenberg, M.7
  • 12
    • 77950683098 scopus 로고    scopus 로고
    • An alpha-galactosylceramide C20:2 N-acyl variant enhances anti-inflammatory and regulatory T cell-independent responses that prevent type 1 diabetes
    • Ly, D., Tohn, R., Rubin, B., Blumenfeld, H., Besra, G. S., Veerapen, N., Porcelli, S. A. et al., An alpha-galactosylceramide C20:2 N-acyl variant enhances anti-inflammatory and regulatory T cell-independent responses that prevent type 1 diabetes. Clin. Exp. Immunol. 2010. 160: 185-198.
    • (2010) Clin. Exp. Immunol. , vol.160 , pp. 185-198
    • Ly, D.1    Tohn, R.2    Rubin, B.3    Blumenfeld, H.4    Besra, G.S.5    Veerapen, N.6    Porcelli, S.A.7
  • 13
    • 0034786013 scopus 로고    scopus 로고
    • The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice
    • Hong, S., Wilson, M. T., Serizawa, I., Wu, L., Singh, N., Naidenko, O. V., Miura, T. et al., The natural killer T-cell ligand alpha-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice. Nat. Med. 2001. 7: 1052-1056.
    • (2001) Nat. Med. , vol.7 , pp. 1052-1056
    • Hong, S.1    Wilson, M.T.2    Serizawa, I.3    Wu, L.4    Singh, N.5    Naidenko, O.V.6    Miura, T.7
  • 14
    • 0035869449 scopus 로고    scopus 로고
    • NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen
    • Laloux, V., Beaudoin, L., Jeske, D., Carnaud, C. and Lehuen, A., NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen. J. Immunol. 2001. 166: 3749-3756.
    • (2001) J. Immunol. , vol.166 , pp. 3749-3756
    • Laloux, V.1    Beaudoin, L.2    Jeske, D.3    Carnaud, C.4    Lehuen, A.5
  • 15
    • 0036906618 scopus 로고    scopus 로고
    • NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells
    • Beaudoin, L., Laloux, V., Novak, J., Lucas, B. and Lehuen, A., NKT cells inhibit the onset of diabetes by impairing the development of pathogenic T cells specific for pancreatic beta cells. Immunity 2002. 17: 725-736.
    • (2002) Immunity , vol.17 , pp. 725-736
    • Beaudoin, L.1    Laloux, V.2    Novak, J.3    Lucas, B.4    Lehuen, A.5
  • 16
    • 19944431804 scopus 로고    scopus 로고
    • Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes
    • Chen, Y. G., Choisy-Rossi, C. M., Holl, T. M., Chapman, H. D., Besra, G. S., Porcelli, S. A., Shaffer, D. J. et al., Activated NKT cells inhibit autoimmune diabetes through tolerogenic recruitment of dendritic cells to pancreatic lymph nodes. J. Immunol. 2005. 174: 1196-1204.
    • (2005) J. Immunol. , vol.174 , pp. 1196-1204
    • Chen, Y.G.1    Choisy-Rossi, C.M.2    Holl, T.M.3    Chapman, H.D.4    Besra, G.S.5    Porcelli, S.A.6    Shaffer, D.J.7
  • 17
    • 0035923675 scopus 로고    scopus 로고
    • Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets
    • Naumov, Y. N., Bahjat, K. S., Gausling, R., Abraham, R., Exley, M. A., Koezuka, Y., Balk, S. B. et al., Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets. Proc. Natl. Acad. Sci. USA 2001. 98: 13838-13843.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 13838-13843
    • Naumov, Y.N.1    Bahjat, K.S.2    Gausling, R.3    Abraham, R.4    Exley, M.A.5    Koezuka, Y.6    Balk, S.B.7
  • 18
    • 53149095477 scopus 로고    scopus 로고
    • Ligand-dependent induction of noninflammatory dendritic cells by anergic invariant NKT cells minimizes autoimmune inflammation
    • Wang, J., Cho, S., Ueno, A., Cheng, L., Xu, B. Y., Desrosiers, M. D., Shi, Y. et al., Ligand-dependent induction of noninflammatory dendritic cells by anergic invariant NKT cells minimizes autoimmune inflammation. J. Immunol. 2008. 181: 2438-2445.
    • (2008) J. Immunol. , vol.181 , pp. 2438-2445
    • Wang, J.1    Cho, S.2    Ueno, A.3    Cheng, L.4    Xu, B.Y.5    Desrosiers, M.D.6    Shi, Y.7
  • 19
    • 33748500822 scopus 로고    scopus 로고
    • Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells
    • Ly, D., Mi, Q. S., Hussain, S. and Delovitch, T. L., Protection from type 1 diabetes by invariant NK T cells requires the activity of CD4+CD25+ regulatory T cells. J. Immunol. 2006. 177: 3695-3704.
    • (2006) J. Immunol. , vol.177 , pp. 3695-3704
    • Ly, D.1    Mi, Q.S.2    Hussain, S.3    Delovitch, T.L.4
  • 22
    • 33744479421 scopus 로고    scopus 로고
    • Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
    • Ochando, J. C., Homma, C., Yang, Y., Hidalgo, A., Garin, A., Tacke, F., Angeli, V. et al., Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat. Immunol. 2006. 7: 652-662.
    • (2006) Nat. Immunol. , vol.7 , pp. 652-662
    • Ochando, J.C.1    Homma, C.2    Yang, Y.3    Hidalgo, A.4    Garin, A.5    Tacke, F.6    Angeli, V.7
  • 23
    • 34848915783 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase
    • Sharma, M. D., Baban, B., Chandler, P., Hou, D. Y., Singh, N., Yagita, H., Azuma, M. et al., Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2, 3-dioxygenase. J. Clin. Invest. 2007. 117: 2570-2582.
    • (2007) J. Clin. Invest. , vol.117 , pp. 2570-2582
    • Sharma, M.D.1    Baban, B.2    Chandler, P.3    Hou, D.Y.4    Singh, N.5    Yagita, H.6    Azuma, M.7
  • 24
    • 54549096767 scopus 로고    scopus 로고
    • CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
    • Hadeiba, H., Sato, T., Habtezion, A., Oderup, C., Pan, J. and Butcher, E. C., CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat. Immunol. 2008. 9: 1253-1260.
    • (2008) Nat. Immunol. , vol.9 , pp. 1253-1260
    • Hadeiba, H.1    Sato, T.2    Habtezion, A.3    Oderup, C.4    Pan, J.5    Butcher, E.C.6
  • 25
    • 0036913215 scopus 로고    scopus 로고
    • Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis
    • Frigerio, S., Junt, T., Lu, B., Gerard, C., Zumsteg, U., Hollander, G. A. and Piali, L., Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat. Med. 2002. 8: 1414-1420.
    • (2002) Nat. Med. , vol.8 , pp. 1414-1420
    • Frigerio, S.1    Junt, T.2    Lu, B.3    Gerard, C.4    Zumsteg, U.5    Hollander, G.A.6    Piali, L.7
  • 26
    • 84866359284 scopus 로고    scopus 로고
    • Acceleration of diabetes development in CXC chemokine receptor 3 (CXCR3)-deficient NOD mice
    • Yamada, Y., Okubo, Y., Shimada, A., Oikawa, Y., Yamada, S., Narumi, S., Matsushima, K. et al., Acceleration of diabetes development in CXC chemokine receptor 3 (CXCR3)-deficient NOD mice. Diabetologia 2012. 55: 2238-2245.
    • (2012) Diabetologia , vol.55 , pp. 2238-2245
    • Yamada, Y.1    Okubo, Y.2    Shimada, A.3    Oikawa, Y.4    Yamada, S.5    Narumi, S.6    Matsushima, K.7
  • 28
    • 0035865315 scopus 로고    scopus 로고
    • Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex
    • Carnaud, C., Gombert, J., Donnars, O., Garchon, H. and Herbelin, A., Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex. J. Immunol. 2001. 166: 2404-2411.
    • (2001) J. Immunol. , vol.166 , pp. 2404-2411
    • Carnaud, C.1    Gombert, J.2    Donnars, O.3    Garchon, H.4    Herbelin, A.5
  • 30
    • 25444519199 scopus 로고    scopus 로고
    • Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells
    • Kent, S. C., Chen, Y., Clemmings, S. M., Viglietta, V., Kenyon, N. S., Ricordi, C., Hering, B. et al., Loss of IL-4 secretion from human type 1a diabetic pancreatic draining lymph node NKT cells. J. Immunol. 2005. 175: 4458-4464.
    • (2005) J. Immunol. , vol.175 , pp. 4458-4464
    • Kent, S.C.1    Chen, Y.2    Clemmings, S.M.3    Viglietta, V.4    Kenyon, N.S.5    Ricordi, C.6    Hering, B.7
  • 31
    • 33846469009 scopus 로고    scopus 로고
    • Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator
    • Forestier, C., Takaki, T., Molano, A., Im, J. S., Baine, I., Jerud, E. S., Illarionov, P. et al., Improved outcomes in NOD mice treated with a novel Th2 cytokine-biasing NKT cell activator. J. Immunol. 2007. 178: 1415-1425.
    • (2007) J. Immunol. , vol.178 , pp. 1415-1425
    • Forestier, C.1    Takaki, T.2    Molano, A.3    Im, J.S.4    Baine, I.5    Jerud, E.S.6    Illarionov, P.7
  • 33
    • 0028222756 scopus 로고
    • Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse
    • Pennline, K. J., Roque-Gaffney, E. and Monahan, M., Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse. Clin. Immunol. Immunopathol. 1994. 71: 169-175.
    • (1994) Clin. Immunol. Immunopathol. , vol.71 , pp. 169-175
    • Pennline, K.J.1    Roque-Gaffney, E.2    Monahan, M.3
  • 34
    • 0027272228 scopus 로고
    • Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice
    • Rapoport, M. J., Jaramillo, A., Zipris, D., Lazarus, A. H., Serreze, D. V., Leiter, E. H., Cyopick, P. et al., Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice. J. Exp. Med. 1993. 178: 87-99.
    • (1993) J. Exp. Med. , vol.178 , pp. 87-99
    • Rapoport, M.J.1    Jaramillo, A.2    Zipris, D.3    Lazarus, A.H.4    Serreze, D.V.5    Leiter, E.H.6    Cyopick, P.7
  • 35
    • 2342650811 scopus 로고    scopus 로고
    • Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells
    • Mi, Q. S., Ly, D., Zucker, P., McGarry, M. and Delovitch, T. L., Interleukin-4 but not interleukin-10 protects against spontaneous and recurrent type 1 diabetes by activated CD1d-restricted invariant natural killer T-cells. Diabetes 2004. 53: 1303-1310.
    • (2004) Diabetes , vol.53 , pp. 1303-1310
    • Mi, Q.S.1    Ly, D.2    Zucker, P.3    McGarry, M.4    Delovitch, T.L.5
  • 36
    • 0034691205 scopus 로고    scopus 로고
    • Multiple differences in gene expression in regulatory Valpha 24Jalpha Q T cells from identical twins discordant for type I diabetes
    • Wilson, S. B., Kent, S. C., Horton, H. F., Hill, A. A., Bollyky, P. L., Hafler, D. A., Strominger, J. L. et al., Multiple differences in gene expression in regulatory Valpha 24Jalpha Q T cells from identical twins discordant for type I diabetes. Proc. Natl. Acad. Sci. USA 2000. 97: 7411-7416.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7411-7416
    • Wilson, S.B.1    Kent, S.C.2    Horton, H.F.3    Hill, A.A.4    Bollyky, P.L.5    Hafler, D.A.6    Strominger, J.L.7
  • 37
    • 13544252802 scopus 로고    scopus 로고
    • Inhibition of T cell differentiation into effectors by NKT cells requires cell contacts
    • Novak, J., Beaudoin, L., Griseri, T. and Lehuen, A., Inhibition of T cell differentiation into effectors by NKT cells requires cell contacts. J. Immunol. 2005. 174: 1954-1961.
    • (2005) J. Immunol. , vol.174 , pp. 1954-1961
    • Novak, J.1    Beaudoin, L.2    Griseri, T.3    Lehuen, A.4
  • 38
    • 33846494233 scopus 로고    scopus 로고
    • Prevention of type 1 diabetes by invariant NKT cells is independent of peripheral CD1d expression
    • Novak, J., Beaudoin, L., Park, S., Griseri, T., Teyton, L., Bendelac, A. and Lehuen, A., Prevention of type 1 diabetes by invariant NKT cells is independent of peripheral CD1d expression. J. Immunol. 2007. 178: 1332-1340.
    • (2007) J. Immunol. , vol.178 , pp. 1332-1340
    • Novak, J.1    Beaudoin, L.2    Park, S.3    Griseri, T.4    Teyton, L.5    Bendelac, A.6    Lehuen, A.7
  • 39
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva, M. and O'Garra, A., The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 2010. 10: 170-181.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 40
    • 0037357579 scopus 로고    scopus 로고
    • The control of immunity and tolerance by dendritic cell
    • Steinman, R. M., The control of immunity and tolerance by dendritic cell. Pathol. Biol. 2003. 51: 59-60.
    • (2003) Pathol. Biol. , vol.51 , pp. 59-60
    • Steinman, R.M.1
  • 41
    • 33746369415 scopus 로고    scopus 로고
    • Regulatory T-cell physiology and application to treat autoimmunity
    • Tang, Q. and Bluestone, J. A., Regulatory T-cell physiology and application to treat autoimmunity. Immunol. Rev. 2006. 212: 217-237.
    • (2006) Immunol. Rev. , vol.212 , pp. 217-237
    • Tang, Q.1    Bluestone, J.A.2
  • 42
    • 38449111402 scopus 로고    scopus 로고
    • The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse
    • Saxena, V., Ondr, J. K., Magnusen, A. F., Munn, D. H. and Katz, J. D., The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J. Immunol. 2007. 179: 5041-5053.
    • (2007) J. Immunol. , vol.179 , pp. 5041-5053
    • Saxena, V.1    Ondr, J.K.2    Magnusen, A.F.3    Munn, D.H.4    Katz, J.D.5
  • 43
    • 77955896776 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development
    • Martin-Gayo, E., Sierra-Filardi, E., Corbi, A. L. and Toribio, M. L., Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development. Blood. 2010. 115: 5366-5375.
    • (2010) Blood. , vol.115 , pp. 5366-5375
    • Martin-Gayo, E.1    Sierra-Filardi, E.2    Corbi, A.L.3    Toribio, M.L.4
  • 44
    • 33846438598 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand
    • Ito, T., Yang, M., Wang, Y. H., Lande, R., Gregorio, J., Perng, O. A., Qin, X. F. et al., Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. J. Exp. Med. 2007. 204: 105-115.
    • (2007) J. Exp. Med. , vol.204 , pp. 105-115
    • Ito, T.1    Yang, M.2    Wang, Y.H.3    Lande, R.4    Gregorio, J.5    Perng, O.A.6    Qin, X.F.7
  • 45
    • 77449115674 scopus 로고    scopus 로고
    • Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette
    • Driver, J. P., Scheuplein, F., Chen, Y. G., Grier, A. E., Wilson, S. B. and Serreze, D. V., Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette. Diabetes 2010. 59: 423-432.
    • (2010) Diabetes , vol.59 , pp. 423-432
    • Driver, J.P.1    Scheuplein, F.2    Chen, Y.G.3    Grier, A.E.4    Wilson, S.B.5    Serreze, D.V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.