All-trans retinoic acid inhibits type 1 diabetes by T regulatory(Treg)- dependent suppression of interferon-γ-producing T-cells without affecting Th17 cells

Diabetes

Volumn 58, Issue 1, 2009, Pages 146-155

  Van Yang Hau, ^a,b   Lee, Wen Hui ^a   Ortiz, Serina ^a   Lee, Mi Heon ^a   Qin, Han Jun ^a   Liu, Chih Pin ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 17; INTERLEUKIN 4; RETINOIC ACID; STAT4 PROTEIN; TRANSCRIPTION FACTOR FOXP3; ANTINEOPLASTIC AGENT; GRANZYME; INTERLEUKIN 2 RECEPTOR ALPHA;

ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; IMMUNOLOGICAL TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SPLEEN CELL; ANIMAL; DRUG EFFECT; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NONOBESE DIABETIC MOUSE; T LYMPHOCYTE;

ANIMALS; ANTINEOPLASTIC AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; FEMALE; GRANZYMES; INTERFERON-GAMMA; INTERLEUKIN-17; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-4; MICE; MICE, INBRED NOD; MICE, SCID; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TRETINOIN;

EID: 63249133189     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-1154     Document Type: Article

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