NKG2D blockade facilitates diabetes prevention by antigen-specific Tregs in a virus-induced model of diabetes

Journal of Autoimmunity

Volumn 40, Issue 1, 2013, Pages 66-73

  Van Belle, Tom L ^a   Ling, Ellie ^a   Haase, Claus ^b   Bresson, Damien ^a   Ursø, Birgitte ^b   Von Herrath, Matthias G ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Adaptive immune system; Antigen specific; Autoimmune diabetes; Immune therapy; Regulatory T cells

Indexed keywords

CD4 ANTIBODY; GLUTAMATE DECARBOXYLASE 65; MONOCLONAL ANTIBODY; NATURAL KILLER CELL RECEPTOR NKG2D; NKG2D MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL THERAPY; CONTROLLED STUDY; DIABETOGENESIS; EXPERIMENTAL DIABETES MELLITUS; FEMALE; IMMUNOTHERAPY; LYMPH NODE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; REGULATORY T LYMPHOCYTE; SPLEEN; UPREGULATION;

ANIMALS; ANTIBODIES; CD8-POSITIVE T-LYMPHOCYTES; DIABETES MELLITUS, TYPE 1; KILLER CELLS, NATURAL; LYMPH NODES; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, INBRED NOD; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; PANCREAS; SPLEEN; T-LYMPHOCYTES, REGULATORY;

EID: 84873724732     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2012.08.001     Document Type: Article

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