Extensive site-directed mutagenesis reveals interconnected functional units in the alkaline phosphatase active site

eLife

Volumn 2015, Issue 4, 2015, Pages 1-76

  Sunden, Fanny ^a   Peck, Ariana ^a   Salzman, Julia ^a   Ressl, Susanne ^b   Herschlag, Daniel ^a  

^a STANFORD UNIVERSITY   (United States)

^b INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; MALTOSE BINDING PROTEIN;

ARTICLE; CATALYSIS; CONCENTRATION RESPONSE; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME SUBSTRATE; HYDROGEN BOND; MATHEMATICAL MODEL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; BINDING SITE; CHEMISTRY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; KINETICS; METABOLISM; MOLECULAR MODEL; PROCEDURES;

ALKALINE PHOSPHATASE; BINDING SITES; CATALYSIS; ESCHERICHIA COLI; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED;

EID: 84929156528     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.06181     Document Type: Article

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