Genome engineering of mammalian haploid embryonic stem cells using the cas9/RNA system

PeerJ

Volumn 2013, Issue 1, 2013, Pages

  Horii, Takuro ^a   Morita, Sumiyo ^a   Kimura, Mika ^a   Kobayashi, Ryouhei ^a   Tamura, Daiki ^a   Takahashi, Ryou u ^b   Kimura, Hironobu ^c   Suetake, Isao ^c   Ohata, Hirokazu ^b   Okamoto, Koji ^b   Tajima, Shoji ^c   Ochiya, Takahiro ^b   Abe, Yumiko ^a   Hatada, Izuho ^a  

^a GUNMA UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

CRISPR Cas; Embryonic stem cells; Genome engineering; Haploid; Tet1; Tet2; Tet3

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; CAS9 NUCLEASE; GLYCOGEN SYNTHASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEASE; OCTAMER TRANSCRIPTION FACTOR 4; RNA; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR GATA 6; TRANSCRIPTION FACTOR NANOG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMOSOME DELETION; CHROMOSOME INVERSION; CONTROLLED STUDY; DNA MODIFICATION; DNA SEQUENCE; EMBRYO; EMBRYONIC STEM CELL; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE DISRUPTION; GENE TARGETING; GENETIC ENGINEERING; GENETIC TRANSFECTION; GENOME; HAPLOIDY; MOUSE; NONHUMAN; OOCYTE; PARTHENOGENESIS; PHENOTYPE; POLYMERASE CHAIN REACTION; TET1 GENE; TET2 GENE; TET3 GENE;

EID: 84891501836     PISSN: None     EISSN: 21678359     Source Type: Journal    
DOI: 10.7717/peerj.230     Document Type: Article

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