메뉴 건너뛰기




Volumn 42, Issue 4, 2015, Pages 141-149

A Toolkit of CRISPR-Based Genome Editing Systems in Drosophila

Author keywords

Cas9; CRISPR; Drosophila; Genome editing; Off target; SgRNA

Indexed keywords

DNA; CASPASE 9; DROSOPHILA PROTEIN;

EID: 84928826662     PISSN: 16738527     EISSN: 18735533     Source Type: Journal    
DOI: 10.1016/j.jgg.2015.02.007     Document Type: Review
Times cited : (33)

References (88)
  • 1
    • 84891722219 scopus 로고    scopus 로고
    • Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
    • Auer T.O., Duroure K., De Cian A., Concordet J.-P., Del Bene F. Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair. Genome Res. 2014, 24:142-153.
    • (2014) Genome Res. , vol.24 , pp. 142-153
    • Auer, T.O.1    Duroure, K.2    De Cian, A.3    Concordet, J.-P.4    Del Bene, F.5
  • 2
    • 84887902944 scopus 로고    scopus 로고
    • Accelerated homologous recombination and subsequent genome modification in Drosophila
    • Baena-Lopez L.A., Alexandre C., Mitchell A., Pasakarnis L., Vincent J.-P. Accelerated homologous recombination and subsequent genome modification in Drosophila. Development 2013, 140:4818-4825.
    • (2013) Development , vol.140 , pp. 4818-4825
    • Baena-Lopez, L.A.1    Alexandre, C.2    Mitchell, A.3    Pasakarnis, L.4    Vincent, J.-P.5
  • 4
    • 84899134190 scopus 로고    scopus 로고
    • CRISPR-Cas systems: prokaryotes upgrade to adaptive immunity
    • Barrangou R., Marraffini L.A. CRISPR-Cas systems: prokaryotes upgrade to adaptive immunity. Mol. Cell 2014, 54:234-244.
    • (2014) Mol. Cell , vol.54 , pp. 234-244
    • Barrangou, R.1    Marraffini, L.A.2
  • 5
    • 84893709652 scopus 로고    scopus 로고
    • CRISPR/Cas9 and genome editing in Drosophila
    • Bassett A.R., Liu J.-L. CRISPR/Cas9 and genome editing in Drosophila. J. Genet. Genomics 2014, 41:7-19.
    • (2014) J. Genet. Genomics , vol.41 , pp. 7-19
    • Bassett, A.R.1    Liu, J.-L.2
  • 6
    • 84892437994 scopus 로고    scopus 로고
    • Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system
    • Bassett A.R., Tibbit C., Ponting C.P., Liu J.-L. Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. Cell Rep. 2013, 4:220-228.
    • (2013) Cell Rep. , vol.4 , pp. 220-228
    • Bassett, A.R.1    Tibbit, C.2    Ponting, C.P.3    Liu, J.-L.4
  • 7
    • 84881060423 scopus 로고    scopus 로고
    • Donor DNA utilization during gene targeting with zinc-finger nucleases
    • Beumer K.J.K., Trautman J.K.J., Mukherjee K., Carroll D. Donor DNA utilization during gene targeting with zinc-finger nucleases. G3 (Bethesda) 2013, 3:657-664.
    • (2013) G3 (Bethesda) , vol.3 , pp. 657-664
    • Beumer, K.J.K.1    Trautman, J.K.J.2    Mukherjee, K.3    Carroll, D.4
  • 8
    • 23844505202 scopus 로고    scopus 로고
    • Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin
    • Bolotin A., Quinquis B., Sorokin A., Ehrlich S.D. Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin. Microbiology 2005, 151:2551-2561.
    • (2005) Microbiology , vol.151 , pp. 2551-2561
    • Bolotin, A.1    Quinquis, B.2    Sorokin, A.3    Ehrlich, S.D.4
  • 9
    • 84897440729 scopus 로고    scopus 로고
    • To acquire or resist: the complex biological effects of CRISPR-Cas systems
    • Bondy-Denomy J., Davidson A.R. To acquire or resist: the complex biological effects of CRISPR-Cas systems. Trends Microbiol. 2014, 22:218-225.
    • (2014) Trends Microbiol. , vol.22 , pp. 218-225
    • Bondy-Denomy, J.1    Davidson, A.R.2
  • 10
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand A.H., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 1993, 118:401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 13
    • 84925004001 scopus 로고    scopus 로고
    • An enhanced gene targeting toolkit for Drosophila: Golic+
    • Chen H.-M., Huang Y., Pfeiffer B.D., Yao X., Lee T. An enhanced gene targeting toolkit for Drosophila: Golic+. Genetics 2015, 199:683-694.
    • (2015) Genetics , vol.199 , pp. 683-694
    • Chen, H.-M.1    Huang, Y.2    Pfeiffer, B.D.3    Yao, X.4    Lee, T.5
  • 15
    • 77957935381 scopus 로고    scopus 로고
    • CRISPR/Cas system and its role in phage-bacteria interactions
    • Deveau H., Garneau J.E., Moineau S. CRISPR/Cas system and its role in phage-bacteria interactions. Annu. Rev. Microbiol. 2010, 64:475-493.
    • (2010) Annu. Rev. Microbiol. , vol.64 , pp. 475-493
    • Deveau, H.1    Garneau, J.E.2    Moineau, S.3
  • 16
    • 84884904381 scopus 로고    scopus 로고
    • Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination
    • Dickinson D.J., Ward J.D., Reiner D.J., Goldstein B. Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. Nat. Methods 2013, 10:1028-1034.
    • (2013) Nat. Methods , vol.10 , pp. 1028-1034
    • Dickinson, D.J.1    Ward, J.D.2    Reiner, D.J.3    Goldstein, B.4
  • 19
    • 84896929630 scopus 로고    scopus 로고
    • Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
    • Fu Y., Sander J.D., Reyon D., Cascio V.M., Joung J.K. Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nat. Biotechnol. 2014, 32:279-284.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 279-284
    • Fu, Y.1    Sander, J.D.2    Reyon, D.3    Cascio, V.M.4    Joung, J.K.5
  • 20
    • 84866859751 scopus 로고    scopus 로고
    • Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
    • Gasiunas G., Barrangou R., Horvath P., Siksnys V. Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria. Proc. Natl. Acad. Sci. USA 2012, 109:E2579-E2586.
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. E2579-E2586
    • Gasiunas, G.1    Barrangou, R.2    Horvath, P.3    Siksnys, V.4
  • 21
    • 84910658482 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila
    • Gokcezade J., Sienski G., Duchek P. Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila. G3 (Bethesda) 2014, 4:2279-2282.
    • (2014) G3 (Bethesda) , vol.4 , pp. 2279-2282
    • Gokcezade, J.1    Sienski, G.2    Duchek, P.3
  • 24
    • 34248400310 scopus 로고    scopus 로고
    • A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes
    • Haft D.H., Selengut J., Mongodin E.F., Nelson K.E. A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes. PLoS Comput. Biol. 2005, 1:e60.
    • (2005) PLoS Comput. Biol. , vol.1 , pp. e60
    • Haft, D.H.1    Selengut, J.2    Mongodin, E.F.3    Nelson, K.E.4
  • 26
    • 84855475577 scopus 로고    scopus 로고
    • Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site
    • Hatoum-Aslan A., Maniv I., Marraffini L.A. Mature clustered, regularly interspaced, short palindromic repeats RNA (crRNA) length is measured by a ruler mechanism anchored at the precursor processing site. Proc. Natl. Acad. Sci. USA 2011, 108:21218-21222.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 21218-21222
    • Hatoum-Aslan, A.1    Maniv, I.2    Marraffini, L.A.3
  • 27
    • 77956498326 scopus 로고    scopus 로고
    • Sequence- and structure-specific RNA processing by a CRISPR endonuclease
    • Haurwitz R.E., Jinek M., Wiedenheft B., Zhou K., Doudna J.A. Sequence- and structure-specific RNA processing by a CRISPR endonuclease. Science 2010, 329:1355-1358.
    • (2010) Science , vol.329 , pp. 1355-1358
    • Haurwitz, R.E.1    Jinek, M.2    Wiedenheft, B.3    Zhou, K.4    Doudna, J.A.5
  • 32
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR-Cas9 for genome engineering
    • Hsu P.D., Lander E.S., Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell 2014, 157:1262-1278.
    • (2014) Cell , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 35
    • 0023600057 scopus 로고
    • Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product
    • Ishino Y., Shinagawa H., Makino K., Amemura M., Nakata A. Nucleotide sequence of the iap gene, responsible for alkaline phosphatase isozyme conversion in Escherichia coli, and identification of the gene product. J. Bacteriol. 1987, 169:5429-5433.
    • (1987) J. Bacteriol. , vol.169 , pp. 5429-5433
    • Ishino, Y.1    Shinagawa, H.2    Makino, K.3    Amemura, M.4    Nakata, A.5
  • 36
    • 0036267740 scopus 로고    scopus 로고
    • Identification of genes that are associated with DNA repeats in prokaryotes
    • Jansen R., Embden J.D., Gaastra W., Schouls L.M. Identification of genes that are associated with DNA repeats in prokaryotes. Mol. Microbiol. 2002, 43:1565-1575.
    • (2002) Mol. Microbiol. , vol.43 , pp. 1565-1575
    • Jansen, R.1    Embden, J.D.2    Gaastra, W.3    Schouls, L.M.4
  • 37
  • 38
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek M., Chylinski K., Fonfara I., Hauer M., Doudna J.A., Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 2012, 337:816-821.
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 41
    • 84884925278 scopus 로고    scopus 로고
    • Highly improved gene targeting by germline-specific Cas9 expression in Drosophila
    • Kondo S., Ueda R. Highly improved gene targeting by germline-specific Cas9 expression in Drosophila. Genetics 2013, 195:715-721.
    • (2013) Genetics , vol.195 , pp. 715-721
    • Kondo, S.1    Ueda, R.2
  • 43
    • 84903545084 scopus 로고    scopus 로고
    • Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
    • Kuscu C., Arslan S., Singh R., Thorpe J., Adli M. Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease. Nat. Biotechnol. 2014, 32:677-683.
    • (2014) Nat. Biotechnol. , vol.32 , pp. 677-683
    • Kuscu, C.1    Arslan, S.2    Singh, R.3    Thorpe, J.4    Adli, M.5
  • 44
    • 84903175627 scopus 로고    scopus 로고
    • Haloarcula hispanica CRISPR authenticates PAM of a target sequence to prime discriminative adaptation
    • Li M., Wang R., Xiang H. Haloarcula hispanica CRISPR authenticates PAM of a target sequence to prime discriminative adaptation. Nucleic Acids Res. 2014, 42:7226-7235.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 7226-7235
    • Li, M.1    Wang, R.2    Xiang, H.3
  • 45
    • 85027939303 scopus 로고    scopus 로고
    • Strategies for gene disruption in Drosophila
    • Lin S.-C., Chang Y.-Y., Chan C.-C. Strategies for gene disruption in Drosophila. Cell Biosci. 2014, 4:63.
    • (2014) Cell Biosci. , vol.4 , pp. 63
    • Lin, S.-C.1    Chang, Y.-Y.2    Chan, C.-C.3
  • 46
    • 84893651502 scopus 로고    scopus 로고
    • Efficient gene targeting in zebrafish mediated by a zebrafish-codon-optimized Cas9 and evaluation of off-targeting effect
    • Liu D., Wang Z., Xiao A., Zhang Y., Li W., Zu Y., Yao S., Lin S., Zhang B. Efficient gene targeting in zebrafish mediated by a zebrafish-codon-optimized Cas9 and evaluation of off-targeting effect. J. Genet. Genomics 2014, 41:43-46.
    • (2014) J. Genet. Genomics , vol.41 , pp. 43-46
    • Liu, D.1    Wang, Z.2    Xiao, A.3    Zhang, Y.4    Li, W.5    Zu, Y.6    Yao, S.7    Lin, S.8    Zhang, B.9
  • 48
    • 79960554003 scopus 로고    scopus 로고
    • Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems
    • Makarova K.S., Aravind L., Wolf Y.I., Koonin E.V. Unification of Cas protein families and a simple scenario for the origin and evolution of CRISPR-Cas systems. Biol. Direct 2011, 6:38.
    • (2011) Biol. Direct , vol.6 , pp. 38
    • Makarova, K.S.1    Aravind, L.2    Wolf, Y.I.3    Koonin, E.V.4
  • 49
    • 34248374277 scopus 로고    scopus 로고
    • A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action
    • Makarova K.S., Grishin N.V., Shabalina S.A., Wolf Y.I., Koonin E.V. A putative RNA-interference-based immune system in prokaryotes: computational analysis of the predicted enzymatic machinery, functional analogies with eukaryotic RNAi, and hypothetical mechanisms of action. Biol. Direct 2006, 1:7.
    • (2006) Biol. Direct , vol.1 , pp. 7
    • Makarova, K.S.1    Grishin, N.V.2    Shabalina, S.A.3    Wolf, Y.I.4    Koonin, E.V.5
  • 51
    • 84884160273 scopus 로고    scopus 로고
    • CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
    • Mali P., Aach J., Stranges P.B., Esvelt K.M., Moosburner M., Kosuri S., Yang L., Church G.M. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering. Nat. Biotechnol. 2013, 31:833-838.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 833-838
    • Mali, P.1    Aach, J.2    Stranges, P.B.3    Esvelt, K.M.4    Moosburner, M.5    Kosuri, S.6    Yang, L.7    Church, G.M.8
  • 53
    • 57849137502 scopus 로고    scopus 로고
    • CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA
    • Marraffini L.A., Sontheimer E.J. CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA. Science 2008, 322:1843-1845.
    • (2008) Science , vol.322 , pp. 1843-1845
    • Marraffini, L.A.1    Sontheimer, E.J.2
  • 55
    • 0034034401 scopus 로고    scopus 로고
    • Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria
    • Mojica F.J., Díez-Villaseñor C., Soria E., Juez G. Biological significance of a family of regularly spaced repeats in the genomes of Archaea, Bacteria and mitochondria. Mol. Microbiol. 2000, 36:244-246.
    • (2000) Mol. Microbiol. , vol.36 , pp. 244-246
    • Mojica, F.J.1    Díez-Villaseñor, C.2    Soria, E.3    Juez, G.4
  • 56
    • 16444385662 scopus 로고    scopus 로고
    • Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements
    • Mojica F.J.M., Díez-Villaseñor C., García-Martínez J., Soria E. Intervening sequences of regularly spaced prokaryotic repeats derive from foreign genetic elements. J. Mol. Evol. 2005, 60:174-182.
    • (2005) J. Mol. Evol. , vol.60 , pp. 174-182
    • Mojica, F.J.M.1    Díez-Villaseñor, C.2    García-Martínez, J.3    Soria, E.4
  • 57
    • 84865704094 scopus 로고    scopus 로고
    • Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system
    • Nam K.H., Haitjema C., Liu X., Ding F., Wang H., DeLisa M.P., Ke A. Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system. Structure 2012, 20:1574-1584.
    • (2012) Structure , vol.20 , pp. 1574-1584
    • Nam, K.H.1    Haitjema, C.2    Liu, X.3    Ding, F.4    Wang, H.5    DeLisa, M.P.6    Ke, A.7
  • 59
    • 84884155038 scopus 로고    scopus 로고
    • High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
    • Pattanayak V., Lin S., Guilinger J.P., Ma E., Doudna J.A., Liu D.R. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nat. Biotechnol. 2013, 31:839-843.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 839-843
    • Pattanayak, V.1    Lin, S.2    Guilinger, J.P.3    Ma, E.4    Doudna, J.A.5    Liu, D.R.6
  • 61
    • 84904654756 scopus 로고    scopus 로고
    • Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila
    • Port F., Chen H.-M., Lee T., Bullock S.L. Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila. Proc. Natl. Acad. Sci. USA 2014, 111:E2967-E2976.
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. E2967-E2976
    • Port, F.1    Chen, H.-M.2    Lee, T.3    Bullock, S.L.4
  • 62
    • 15844390228 scopus 로고    scopus 로고
    • CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies
    • Pourcel C., Salvignol G., Vergnaud G. CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. Microbiology 2005, 151:653-663.
    • (2005) Microbiology , vol.151 , pp. 653-663
    • Pourcel, C.1    Salvignol, G.2    Vergnaud, G.3
  • 63
    • 84874687019 scopus 로고    scopus 로고
    • Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
    • Qi L.S., Larson M.H., Gilbert L.A., Doudna J.A., Weissman J.S., Arkin A.P., Lim W.A. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell 2013, 152:1173-1183.
    • (2013) Cell , vol.152 , pp. 1173-1183
    • Qi, L.S.1    Larson, M.H.2    Gilbert, L.A.3    Doudna, J.A.4    Weissman, J.S.5    Arkin, A.P.6    Lim, W.A.7
  • 68
    • 84905262730 scopus 로고    scopus 로고
    • Improved vectors and genome-wide libraries for CRISPR screening
    • Sanjana N.E., Shalem O., Zhang F. Improved vectors and genome-wide libraries for CRISPR screening. Nat. Methods 2014, 11:783-784.
    • (2014) Nat. Methods , vol.11 , pp. 783-784
    • Sanjana, N.E.1    Shalem, O.2    Zhang, F.3
  • 69
    • 84888372954 scopus 로고    scopus 로고
    • A simplified and efficient germline-specific CRISPR/Cas9 system for Drosophila genomic engineering
    • Sebo Z.L., Lee H.B., Peng Y., Guo Y. A simplified and efficient germline-specific CRISPR/Cas9 system for Drosophila genomic engineering. Fly (Austin) 2014, 8:52-57.
    • (2014) Fly (Austin) , vol.8 , pp. 52-57
    • Sebo, Z.L.1    Lee, H.B.2    Peng, Y.3    Guo, Y.4
  • 70
    • 84879026965 scopus 로고    scopus 로고
    • Protospacer recognition motifs: mixed identities and functional diversity
    • Shah S.A., Erdmann S., Mojica F.J.M., Garrett R.A. Protospacer recognition motifs: mixed identities and functional diversity. RNA Biol. 2013, 10:891-899.
    • (2013) RNA Biol. , vol.10 , pp. 891-899
    • Shah, S.A.1    Erdmann, S.2    Mojica, F.J.M.3    Garrett, R.A.4
  • 72
    • 0032480981 scopus 로고    scopus 로고
    • A role of Ultrabithorax in morphological differences between Drosophila species
    • Stern D.L. A role of Ultrabithorax in morphological differences between Drosophila species. Nature 1998, 396:463-466.
    • (1998) Nature , vol.396 , pp. 463-466
    • Stern, D.L.1
  • 76
    • 84900862427 scopus 로고    scopus 로고
    • Fine-mapping natural alleles: quantitative complementation to the rescue
    • Turner T.L. Fine-mapping natural alleles: quantitative complementation to the rescue. Mol. Ecol. 2014, 23:2377-2382.
    • (2014) Mol. Ecol. , vol.23 , pp. 2377-2382
    • Turner, T.L.1
  • 78
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
    • Wang H., Yang H., Shivalila C.S., Dawlaty M.M., Cheng A.W., Zhang F., Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 2013, 153:910-918.
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1    Yang, H.2    Shivalila, C.S.3    Dawlaty, M.M.4    Cheng, A.W.5    Zhang, F.6    Jaenisch, R.7
  • 79
    • 84892749369 scopus 로고    scopus 로고
    • Genetic screens in human cells using the CRISPR-Cas9 system
    • Wang T., Wei J.J., Sabatini D.M., Lander E.S. Genetic screens in human cells using the CRISPR-Cas9 system. Science 2014, 343:80-84.
    • (2014) Science , vol.343 , pp. 80-84
    • Wang, T.1    Wei, J.J.2    Sabatini, D.M.3    Lander, E.S.4
  • 80
    • 84924985583 scopus 로고    scopus 로고
    • Fruit flies in biomedical research
    • Wangler M.F., Yamamoto S., Bellen H.J. Fruit flies in biomedical research. Genetics 2015, 199:639-653.
    • (2015) Genetics , vol.199 , pp. 639-653
    • Wangler, M.F.1    Yamamoto, S.2    Bellen, H.J.3
  • 81
    • 84879410743 scopus 로고    scopus 로고
    • TALEN or Cas9-rapid, efficient and specific choices for genome modifications
    • Wei C., Liu J., Yu Z., Zhang B., Gao G., Jiao R. TALEN or Cas9-rapid, efficient and specific choices for genome modifications. J. Genet. Genomics 2013, 40:281-289.
    • (2013) J. Genet. Genomics , vol.40 , pp. 281-289
    • Wei, C.1    Liu, J.2    Yu, Z.3    Zhang, B.4    Gao, G.5    Jiao, R.6
  • 83
    • 84901336231 scopus 로고    scopus 로고
    • Efficient gene knock-out and knock-in with transgenic Cas9 in Drosophila
    • Xue Z., Ren M., Wu M., Dai J., Rong Y.S., Gao G. Efficient gene knock-out and knock-in with transgenic Cas9 in Drosophila. G3 (Bethesda) 2014, 4:925-929.
    • (2014) G3 (Bethesda) , vol.4 , pp. 925-929
    • Xue, Z.1    Ren, M.2    Wu, M.3    Dai, J.4    Rong, Y.S.5    Gao, G.6
  • 84
    • 84910619646 scopus 로고    scopus 로고
    • CRISPR/Cas9 mediates efficient conditional mutagenesis in Drosophila
    • Xue Z., Wu M., Wen K., Ren M., Long L., Zhang X., Gao G. CRISPR/Cas9 mediates efficient conditional mutagenesis in Drosophila. G3 (Bethesda) 2014, 4:2167-2173.
    • (2014) G3 (Bethesda) , vol.4 , pp. 2167-2173
    • Xue, Z.1    Wu, M.2    Wen, K.3    Ren, M.4    Long, L.5    Zhang, X.6    Gao, G.7
  • 85
    • 84884289608 scopus 로고    scopus 로고
    • One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
    • Yang H., Wang H., Shivalila C.S., Cheng A.W., Shi L., Jaenisch R. One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 2013, 154:1370-1379.
    • (2013) Cell , vol.154 , pp. 1370-1379
    • Yang, H.1    Wang, H.2    Shivalila, C.S.3    Cheng, A.W.4    Shi, L.5    Jaenisch, R.6
  • 87
    • 84883809403 scopus 로고    scopus 로고
    • Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila
    • Yu Z., Ren M., Wang Z., Zhang B., Rong Y.S., Jiao R., Gao G. Highly efficient genome modifications mediated by CRISPR/Cas9 in Drosophila. Genetics 2013, 195:289-291.
    • (2013) Genetics , vol.195 , pp. 289-291
    • Yu, Z.1    Ren, M.2    Wang, Z.3    Zhang, B.4    Rong, Y.S.5    Jiao, R.6    Gao, G.7
  • 88
    • 84916878091 scopus 로고    scopus 로고
    • A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila
    • Zhang X., Koolhaas W.H., Schnorrer F. A versatile two-step CRISPR- and RMCE-based strategy for efficient genome engineering in Drosophila. G3 (Bethesda) 2014, 4:2409-2418.
    • (2014) G3 (Bethesda) , vol.4 , pp. 2409-2418
    • Zhang, X.1    Koolhaas, W.H.2    Schnorrer, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.