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Volumn 104, Issue 5, 2014, Pages 314-323

5-Hydroxymethylcytosine: A stable or transient DNA modification?

Author keywords

5 Hydroxymethylcytosine; 5 Methylcytosine; DNA methylation

Indexed keywords

5 CARBOXYLCYTOSINE; 5 FORMYLCYTOSINE; 5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; 5 METHYLCYTOSINE OXIDASE; DNA BASE; DNA METHYLTRANSFERASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG; 5-CARBOXYLCYTOSINE; 5-FORMYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA BINDING PROTEIN;

EID: 84927696607     PISSN: 08887543     EISSN: 10898646     Source Type: Journal    
DOI: 10.1016/j.ygeno.2014.08.015     Document Type: Article
Times cited : (108)

References (120)
  • 1
    • 0016692220 scopus 로고
    • X inactivation, differentiation, and DNA methylation
    • Riggs A.D. X inactivation, differentiation, and DNA methylation. Cytogenet. Cell Genet. 1975, 14:9-25.
    • (1975) Cytogenet. Cell Genet. , vol.14 , pp. 9-25
    • Riggs, A.D.1
  • 2
    • 0016439429 scopus 로고
    • DNA modification mechanisms and gene activity during development
    • Holliday R., Pugh J.E. DNA modification mechanisms and gene activity during development. Science 1975, 187:226-232.
    • (1975) Science , vol.187 , pp. 226-232
    • Holliday, R.1    Pugh, J.E.2
  • 3
    • 0344599272 scopus 로고
    • Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis
    • Saluz H.P., Jiricny J., Jost J.P. Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis. Proc. Natl. Acad. Sci. U. S. A. 1986, 83:7167-7171.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , pp. 7167-7171
    • Saluz, H.P.1    Jiricny, J.2    Jost, J.P.3
  • 4
    • 45449114804 scopus 로고    scopus 로고
    • The colorful history of active DNA demethylation
    • Ooi S.K., Bestor T.H. The colorful history of active DNA demethylation. Cell 2008, 133:1145-1148.
    • (2008) Cell , vol.133 , pp. 1145-1148
    • Ooi, S.K.1    Bestor, T.H.2
  • 5
    • 84892763878 scopus 로고    scopus 로고
    • Reversing DNA methylation: mechanisms, genomics, and biological functions
    • Wu H., Zhang Y. Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell 2014, 156:45-68.
    • (2014) Cell , vol.156 , pp. 45-68
    • Wu, H.1    Zhang, Y.2
  • 6
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S., Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 2009, 324:929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 8
    • 0037350661 scopus 로고    scopus 로고
    • TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
    • Lorsbach R.B., Moore J., Mathew S., Raimondi S.C., Mukatira S.T., Downing J.R. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 2003, 17:637-641.
    • (2003) Leukemia , vol.17 , pp. 637-641
    • Lorsbach, R.B.1    Moore, J.2    Mathew, S.3    Raimondi, S.C.4    Mukatira, S.T.5    Downing, J.R.6
  • 9
    • 0037099537 scopus 로고    scopus 로고
    • LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23)
    • Ono R., Taki T., Taketani T., Taniwaki M., Kobayashi H., Hayashi Y. LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res. 2002, 62:4075-4080.
    • (2002) Cancer Res. , vol.62 , pp. 4075-4080
    • Ono, R.1    Taki, T.2    Taketani, T.3    Taniwaki, M.4    Kobayashi, H.5    Hayashi, Y.6
  • 10
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S., D'Alessio A.C., Taranova O.V., Hong K., Sowers L.C., Zhang Y. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 2010, 466:1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 12
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S., Shen L., Dai Q., Wu S.C., Collins L.B., Swenberg J.A., He C., Zhang Y. Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 2011, 333:1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5    Swenberg, J.A.6    He, C.7    Zhang, Y.8
  • 13
    • 84876946045 scopus 로고    scopus 로고
    • Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics
    • Shen L., Wu H., Diep D., Yamaguchi S., D'Alessio A.C., Fung H.L., Zhang K., Zhang Y. Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell 2013, 153:692-706.
    • (2013) Cell , vol.153 , pp. 692-706
    • Shen, L.1    Wu, H.2    Diep, D.3    Yamaguchi, S.4    D'Alessio, A.C.5    Fung, H.L.6    Zhang, K.7    Zhang, Y.8
  • 16
    • 33847055935 scopus 로고    scopus 로고
    • Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
    • Valinluck V., Sowers L.C. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res. 2007, 67:946-950.
    • (2007) Cancer Res. , vol.67 , pp. 946-950
    • Valinluck, V.1    Sowers, L.C.2
  • 17
    • 84255200412 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
    • Jin S.G., Jiang Y., Qiu R., Rauch T.A., Wang Y., Schackert G., Krex D., Lu Q., Pfeifer G.P. 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res. 2011, 71:7360-7365.
    • (2011) Cancer Res. , vol.71 , pp. 7360-7365
    • Jin, S.G.1    Jiang, Y.2    Qiu, R.3    Rauch, T.A.4    Wang, Y.5    Schackert, G.6    Krex, D.7    Lu, Q.8    Pfeifer, G.P.9
  • 18
    • 84876794613 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine and its potential roles in development and cancer
    • Pfeifer G.P., Kadam S., Jin S.G. 5-Hydroxymethylcytosine and its potential roles in development and cancer. Epigenet. Chromatin 2013, 6:10.
    • (2013) Epigenet. Chromatin , vol.6 , pp. 10
    • Pfeifer, G.P.1    Kadam, S.2    Jin, S.G.3
  • 19
    • 84902298158 scopus 로고    scopus 로고
    • The role of 5-hydroxymethylcytosine in human cancer
    • Pfeifer G.P., Xiong W., Hahn M.A., Jin S.G. The role of 5-hydroxymethylcytosine in human cancer. Cell Tissue Res. 2014, 356:631-641.
    • (2014) Cell Tissue Res. , vol.356 , pp. 631-641
    • Pfeifer, G.P.1    Xiong, W.2    Hahn, M.A.3    Jin, S.G.4
  • 20
    • 79960249232 scopus 로고    scopus 로고
    • Genomic mapping of 5-hydroxymethylcytosine in the human brain
    • Jin S.G., Wu X., Li A.X., Pfeifer G.P. Genomic mapping of 5-hydroxymethylcytosine in the human brain. Nucleic Acids Res. 2011, 39:5015-5024.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5015-5024
    • Jin, S.G.1    Wu, X.2    Li, A.X.3    Pfeifer, G.P.4
  • 26
    • 84871563384 scopus 로고    scopus 로고
    • MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
    • Mellen M., Ayata P., Dewell S., Kriaucionis S., Heintz N. MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell 2012, 151:1417-1430.
    • (2012) Cell , vol.151 , pp. 1417-1430
    • Mellen, M.1    Ayata, P.2    Dewell, S.3    Kriaucionis, S.4    Heintz, N.5
  • 28
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir R.E., Van den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 1999, 23:185-188.
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    Van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 29
    • 67249150482 scopus 로고    scopus 로고
    • Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus
    • Ben-Shachar S., Chahrour M., Thaller C., Shaw C.A., Zoghbi H.Y. Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamus. Hum. Mol. Genet. 2009, 18:2431-2442.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 2431-2442
    • Ben-Shachar, S.1    Chahrour, M.2    Thaller, C.3    Shaw, C.A.4    Zoghbi, H.Y.5
  • 30
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: the mark and its mediators
    • Klose R.J., Bird A.P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 2006, 31:89-97.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 33
    • 84883393151 scopus 로고    scopus 로고
    • Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity
    • Colquitt B.M., Allen W.E., Barnea G., Lomvardas S. Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:14682-14687.
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 14682-14687
    • Colquitt, B.M.1    Allen, W.E.2    Barnea, G.3    Lomvardas, S.4
  • 39
    • 84870856116 scopus 로고    scopus 로고
    • Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
    • Wang T., Pan Q., Lin L., Szulwach K.E., Song C.X., He C., Wu H., Warren S.T., Jin P., Duan R., Li X. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum. Mol. Genet. 2012, 21:5500-5510.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 5500-5510
    • Wang, T.1    Pan, Q.2    Lin, L.3    Szulwach, K.E.4    Song, C.X.5    He, C.6    Wu, H.7    Warren, S.T.8    Jin, P.9    Duan, R.10    Li, X.11
  • 41
    • 84887214395 scopus 로고    scopus 로고
    • Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
    • Maunakea A.K., Chepelev I., Cui K., Zhao K. Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition. Cell Res. 2013, 23:1256-1269.
    • (2013) Cell Res. , vol.23 , pp. 1256-1269
    • Maunakea, A.K.1    Chepelev, I.2    Cui, K.3    Zhao, K.4
  • 45
    • 16444381345 scopus 로고    scopus 로고
    • Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system
    • Feng J., Chang H., Li E., Fan G. Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res. 2005, 79:734-746.
    • (2005) J. Neurosci. Res. , vol.79 , pp. 734-746
    • Feng, J.1    Chang, H.2    Li, E.3    Fan, G.4
  • 47
    • 77954842322 scopus 로고    scopus 로고
    • Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
    • Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
    • (2010) Science , vol.329 , pp. 444-448
    • Wu, H.1    Coskun, V.2    Tao, J.3    Xie, W.4    Ge, W.5    Yoshikawa, K.6    Li, E.7    Zhang, Y.8    Sun, Y.E.9
  • 48
    • 33846909036 scopus 로고    scopus 로고
    • Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair
    • Li Y.Q., Zhou P.Z., Zheng X.D., Walsh C.P., Xu G.L. Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair. Nucleic Acids Res. 2007, 35:390-400.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 390-400
    • Li, Y.Q.1    Zhou, P.Z.2    Zheng, X.D.3    Walsh, C.P.4    Xu, G.L.5
  • 51
    • 84873326535 scopus 로고    scopus 로고
    • A single strand that links multiple neuropathologies in human disease
    • Reynolds J.J., Stewart G.S. A single strand that links multiple neuropathologies in human disease. Brain 2013, 136:14-27.
    • (2013) Brain , vol.136 , pp. 14-27
    • Reynolds, J.J.1    Stewart, G.S.2
  • 52
    • 84868580497 scopus 로고    scopus 로고
    • Transcription blockage by bulky end termini at single-strand breaks in the DNA template: differential effects of 5' and 3' adducts
    • Neil A.J., Belotserkovskii B.P., Hanawalt P.C. Transcription blockage by bulky end termini at single-strand breaks in the DNA template: differential effects of 5' and 3' adducts. Biochemistry 2012, 51:8964-8970.
    • (2012) Biochemistry , vol.51 , pp. 8964-8970
    • Neil, A.J.1    Belotserkovskii, B.P.2    Hanawalt, P.C.3
  • 53
    • 84864722177 scopus 로고    scopus 로고
    • 5-Formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription
    • Kellinger M.W., Song C.X., Chong J., Lu X.Y., He C., Wang D. 5-Formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription. Nat. Struct. Mol. Biol. 2012, 19:831-833.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 831-833
    • Kellinger, M.W.1    Song, C.X.2    Chong, J.3    Lu, X.Y.4    He, C.5    Wang, D.6
  • 54
    • 0035839126 scopus 로고    scopus 로고
    • Epigenetic reprogramming in mammalian development
    • Reik W., Dean W., Walter J. Epigenetic reprogramming in mammalian development. Science 2001, 293:1089-1093.
    • (2001) Science , vol.293 , pp. 1089-1093
    • Reik, W.1    Dean, W.2    Walter, J.3
  • 57
    • 79952763586 scopus 로고    scopus 로고
    • Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
    • Iqbal K., Jin S.G., Pfeifer G.P., Szabo P.E. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:3642-3647.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 3642-3647
    • Iqbal, K.1    Jin, S.G.2    Pfeifer, G.P.3    Szabo, P.E.4
  • 61
    • 84871730721 scopus 로고    scopus 로고
    • H3K9me2 attracts PGC7 in the zygote to prevent Tet3-mediated oxidation of 5-methylcytosine
    • Szabo P.E., Pfeifer G.P. H3K9me2 attracts PGC7 in the zygote to prevent Tet3-mediated oxidation of 5-methylcytosine. J. Mol. Cell Biol. 2012, 4:427-429.
    • (2012) J. Mol. Cell Biol. , vol.4 , pp. 427-429
    • Szabo, P.E.1    Pfeifer, G.P.2
  • 62
    • 80054097425 scopus 로고    scopus 로고
    • Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
    • Inoue A., Zhang Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 2011, 334:194.
    • (2011) Science , vol.334 , pp. 194
    • Inoue, A.1    Zhang, Y.2
  • 63
    • 82655187105 scopus 로고    scopus 로고
    • Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development
    • Inoue A., Shen L., Dai Q., He C., Zhang Y. Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development. Cell Res. 2011, 21:1670-1676.
    • (2011) Cell Res. , vol.21 , pp. 1670-1676
    • Inoue, A.1    Shen, L.2    Dai, Q.3    He, C.4    Zhang, Y.5
  • 71
    • 38349100549 scopus 로고    scopus 로고
    • Epigenetic events in mammalian germ-cell development: reprogramming and beyond
    • Sasaki H., Matsui Y. Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat. Rev. Genet. 2008, 9:129-140.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 129-140
    • Sasaki, H.1    Matsui, Y.2
  • 73
    • 12944308793 scopus 로고    scopus 로고
    • Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice
    • Seki Y., Hayashi K., Itoh K., Mizugaki M., Saitou M., Matsui Y. Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice. Dev. Biol. 2005, 278:440-458.
    • (2005) Dev. Biol. , vol.278 , pp. 440-458
    • Seki, Y.1    Hayashi, K.2    Itoh, K.3    Mizugaki, M.4    Saitou, M.5    Matsui, Y.6
  • 74
    • 84859519339 scopus 로고    scopus 로고
    • Global profiling of DNA methylation erasure in mouse primordial germ cells
    • Guibert S., Forne T., Weber M. Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res. 2012, 22:633-641.
    • (2012) Genome Res. , vol.22 , pp. 633-641
    • Guibert, S.1    Forne, T.2    Weber, M.3
  • 77
    • 84876580247 scopus 로고    scopus 로고
    • New insights into establishment and maintenance of DNA methylation imprints in mammals
    • Kelsey G., Feil R. New insights into establishment and maintenance of DNA methylation imprints in mammals. Philos. Trans. R. Soc. Lond. B Biol. Sci. 2013, 368:20110336.
    • (2013) Philos. Trans. R. Soc. Lond. B Biol. Sci. , vol.368 , pp. 20110336
    • Kelsey, G.1    Feil, R.2
  • 78
    • 42449150457 scopus 로고    scopus 로고
    • DNA methylation reprogramming in the germ line
    • Lees-Murdock D.J., Walsh C.P. DNA methylation reprogramming in the germ line. Adv. Exp. Med. Biol. 2008, 626:1-15.
    • (2008) Adv. Exp. Med. Biol. , vol.626 , pp. 1-15
    • Lees-Murdock, D.J.1    Walsh, C.P.2
  • 79
    • 0027236694 scopus 로고
    • The ontogeny of allele-specific methylation associated with imprinted genes in the mouse
    • Brandeis M., Kafri T., Ariel M., Chaillet J.R., McCarrey J., Razin A., Cedar H. The ontogeny of allele-specific methylation associated with imprinted genes in the mouse. EMBO J. 1993, 12:3669-3677.
    • (1993) EMBO J. , vol.12 , pp. 3669-3677
    • Brandeis, M.1    Kafri, T.2    Ariel, M.3    Chaillet, J.R.4    McCarrey, J.5    Razin, A.6    Cedar, H.7
  • 81
    • 0036333598 scopus 로고    scopus 로고
    • Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells
    • Lee J., Inoue K., Ono R., Ogonuki N., Kohda T., Kaneko-Ishino T., Ogura A., Ishino F. Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells. Development 1807-1817, 129(2002).
    • (2002) Development , vol.129 , pp. 1807-1817
    • Lee, J.1    Inoue, K.2    Ono, R.3    Ogonuki, N.4    Kohda, T.5    Kaneko-Ishino, T.6    Ogura, A.7    Ishino, F.8
  • 82
    • 0037401690 scopus 로고    scopus 로고
    • Erasure of methylation imprinting of Igf2r during mouse primordial germ-cell development
    • Sato S., Yoshimizu T., Sato E., Matsui Y. Erasure of methylation imprinting of Igf2r during mouse primordial germ-cell development. Mol. Reprod. Dev. 2003, 65:41-50.
    • (2003) Mol. Reprod. Dev. , vol.65 , pp. 41-50
    • Sato, S.1    Yoshimizu, T.2    Sato, E.3    Matsui, Y.4
  • 83
    • 84892606041 scopus 로고    scopus 로고
    • Active DNA demethylation is required for complete imprint erasure in primordial germ cells
    • Kawasaki Y., Lee J., Matsuzawa A., Kohda T., Kaneko-Ishino T., Ishino F. Active DNA demethylation is required for complete imprint erasure in primordial germ cells. Sci. Rep. 2014, 4:3658.
    • (2014) Sci. Rep. , vol.4 , pp. 3658
    • Kawasaki, Y.1    Lee, J.2    Matsuzawa, A.3    Kohda, T.4    Kaneko-Ishino, T.5    Ishino, F.6
  • 84
    • 0029142492 scopus 로고
    • Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting
    • Szabo P.E., Mann J.R. Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting. Genes Dev. 1995, 9:1857-1868.
    • (1995) Genes Dev. , vol.9 , pp. 1857-1868
    • Szabo, P.E.1    Mann, J.R.2
  • 85
    • 0036275755 scopus 로고    scopus 로고
    • Allele-specific expression of imprinted genes in mouse migratory primordial germ cells
    • Szabo P.E., Hubner K., Scholer H., Mann J.R. Allele-specific expression of imprinted genes in mouse migratory primordial germ cells. Mech. Dev. 2002, 115:157-160.
    • (2002) Mech. Dev. , vol.115 , pp. 157-160
    • Szabo, P.E.1    Hubner, K.2    Scholer, H.3    Mann, J.R.4
  • 86
    • 84873570094 scopus 로고    scopus 로고
    • Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice
    • Kagiwada S., Kurimoto K., Hirota T., Yamaji M., Saitou M. Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice. EMBO J. 2013, 32:340-353.
    • (2013) EMBO J. , vol.32 , pp. 340-353
    • Kagiwada, S.1    Kurimoto, K.2    Hirota, T.3    Yamaji, M.4    Saitou, M.5
  • 87
    • 77954345408 scopus 로고    scopus 로고
    • Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
    • Hajkova P., Jeffries S.J., Lee C., Miller N., Jackson S.P., Surani M.A. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 2010, 329:78-82.
    • (2010) Science , vol.329 , pp. 78-82
    • Hajkova, P.1    Jeffries, S.J.2    Lee, C.3    Miller, N.4    Jackson, S.P.5    Surani, M.A.6
  • 88
  • 90
    • 84890568163 scopus 로고    scopus 로고
    • Role of Tet1 in erasure of genomic imprinting
    • Yamaguchi S., Shen L., Liu Y., Sendler D., Zhang Y. Role of Tet1 in erasure of genomic imprinting. Nature 2013, 504:460-464.
    • (2013) Nature , vol.504 , pp. 460-464
    • Yamaguchi, S.1    Shen, L.2    Liu, Y.3    Sendler, D.4    Zhang, Y.5
  • 95
    • 77249148019 scopus 로고    scopus 로고
    • Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
    • Popp C., Dean W., Feng S., Cokus S.J., Andrews S., Pellegrini M., Jacobsen S.E., Reik W. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 2010, 463:1101-1105.
    • (2010) Nature , vol.463 , pp. 1101-1105
    • Popp, C.1    Dean, W.2    Feng, S.3    Cokus, S.J.4    Andrews, S.5    Pellegrini, M.6    Jacobsen, S.E.7    Reik, W.8
  • 96
    • 84874655393 scopus 로고    scopus 로고
    • Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming
    • Yamaguchi S., Hong K., Liu R., Inoue A., Shen L., Zhang K., Zhang Y. Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Cell Res. 2013, 23:329-339.
    • (2013) Cell Res. , vol.23 , pp. 329-339
    • Yamaguchi, S.1    Hong, K.2    Liu, R.3    Inoue, A.4    Shen, L.5    Zhang, K.6    Zhang, Y.7
  • 98
    • 77954362183 scopus 로고    scopus 로고
    • Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
    • Jin S.G., Kadam S., Pfeifer G.P. Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine. Nucleic Acids Res. 2010, 38:e125.
    • (2010) Nucleic Acids Res. , vol.38
    • Jin, S.G.1    Kadam, S.2    Pfeifer, G.P.3
  • 103
    • 79956292024 scopus 로고    scopus 로고
    • Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
    • Wu H., D'Alessio A.C., Ito S., Xia K., Wang Z., Cui K., Zhao K., Sun Y.E., Zhang Y. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 2011, 473:389-393.
    • (2011) Nature , vol.473 , pp. 389-393
    • Wu, H.1    D'Alessio, A.C.2    Ito, S.3    Xia, K.4    Wang, Z.5    Cui, K.6    Zhao, K.7    Sun, Y.E.8    Zhang, Y.9
  • 105
    • 79959209733 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
    • Stroud H., Feng S., Morey Kinney S., Pradhan S., Jacobsen S.E. 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biol. 2011, 12:R54.
    • (2011) Genome Biol. , vol.12 , pp. R54
    • Stroud, H.1    Feng, S.2    Morey Kinney, S.3    Pradhan, S.4    Jacobsen, S.E.5
  • 107
    • 84889646827 scopus 로고    scopus 로고
    • 5-Hydroxymethylcytosine profiling as an indicator of cellular state
    • Laird A., Thomson J.P., Harrison D.J., Meehan R.R. 5-Hydroxymethylcytosine profiling as an indicator of cellular state. Epigenomics 2013, 5:655-669.
    • (2013) Epigenomics , vol.5 , pp. 655-669
    • Laird, A.1    Thomson, J.P.2    Harrison, D.J.3    Meehan, R.R.4
  • 111
    • 4043112183 scopus 로고    scopus 로고
    • Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2)
    • Valinluck V., Tsai H.H., Rogstad D.K., Burdzy A., Bird A., Sowers L.C. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res. 2004, 32:4100-4108.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 4100-4108
    • Valinluck, V.1    Tsai, H.H.2    Rogstad, D.K.3    Burdzy, A.4    Bird, A.5    Sowers, L.C.6
  • 112
    • 84901828175 scopus 로고    scopus 로고
    • Effects of Tet-induced oxidation products of 5-methylcytosine on Dnmt1- and DNMT3a-mediated cytosine methylation
    • Ji D., Lin K., Song J., Wang Y. Effects of Tet-induced oxidation products of 5-methylcytosine on Dnmt1- and DNMT3a-mediated cytosine methylation. Mol. Biosyst. 2014, 10:1749-1752.
    • (2014) Mol. Biosyst. , vol.10 , pp. 1749-1752
    • Ji, D.1    Lin, K.2    Song, J.3    Wang, Y.4
  • 113
    • 84455167621 scopus 로고    scopus 로고
    • Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
    • Yildirim O., Li R., Hung J.H., Chen P.B., Dong X., Ee L.S., Weng Z., Rando O.J., Fazzio T.G. Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell 2011, 147:1498-1510.
    • (2011) Cell , vol.147 , pp. 1498-1510
    • Yildirim, O.1    Li, R.2    Hung, J.H.3    Chen, P.B.4    Dong, X.5    Ee, L.S.6    Weng, Z.7    Rando, O.J.8    Fazzio, T.G.9
  • 114
    • 84876278080 scopus 로고    scopus 로고
    • Methylation-dependent and -independent genomic targeting principles of the MBD protein family
    • Baubec T., Ivanek R., Lienert F., Schubeler D. Methylation-dependent and -independent genomic targeting principles of the MBD protein family. Cell 2013, 153:480-492.
    • (2013) Cell , vol.153 , pp. 480-492
    • Baubec, T.1    Ivanek, R.2    Lienert, F.3    Schubeler, D.4
  • 116
  • 118
    • 84901950311 scopus 로고    scopus 로고
    • Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2
    • Zhou T., Xiong J., Wang M., Yang N., Wong J., Zhu B., Xu R.M. Structural basis for hydroxymethylcytosine recognition by the SRA domain of UHRF2. Mol. Cell 2014, 54:879-886.
    • (2014) Mol. Cell , vol.54 , pp. 879-886
    • Zhou, T.1    Xiong, J.2    Wang, M.3    Yang, N.4    Wong, J.5    Zhu, B.6    Xu, R.M.7
  • 120
    • 84886035297 scopus 로고    scopus 로고
    • A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation
    • Iurlaro M., Ficz G., Oxley D., Raiber E.A., Bachman M., Booth M.J., Andrews S., Balasubramanian S., Reik W. A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation. Genome Biol. 2013, 14:R119.
    • (2013) Genome Biol. , vol.14 , pp. R119
    • Iurlaro, M.1    Ficz, G.2    Oxley, D.3    Raiber, E.A.4    Bachman, M.5    Booth, M.J.6    Andrews, S.7    Balasubramanian, S.8    Reik, W.9


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