Transcription blockage by bulky end termini at single-strand breaks in the DNA template: Differential effects of 5′ and 3′ adducts

Biochemistry

Volumn 51, Issue 44, 2012, Pages 8964-8970

  Neil, Alexander J ^a   Belotserkovskii, Boris P ^a   Hanawalt, Philip C ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIFFERENTIAL EFFECT; DNA DAMAGES; DNA STRANDS; DNA-TEMPLATE; HELA CELL; MAMMALIAN CELLS; NUCLEAR EXTRACTS; PHOSPHATE GROUP; RNA POLYMERASE; RNA POLYMERASE II; SINGLE-STRAND BREAKS; TEMPLATE STRAND; TOPOISOMERASES; UNSATURATED ALDEHYDES;

ALDEHYDES; CARBON; DNA; MAMMALS; NUCLEOTIDES; POLYMERS; RNA; UNSATURATED POLYMERS;

TRANSCRIPTION;

BIOTIN; CARBON; CELL EXTRACT; RNA POLYMERASE; RNA POLYMERASE II; THYMINE;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BACTERIOPHAGE T7; BIOTINYLATION; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA TEMPLATE; FEMALE; HELA CELL; HUMAN; HUMAN CELL; MOLECULAR SIZE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; SIGNAL TRANSDUCTION; SINGLE STRANDED DNA BREAK; TRANSCRIPTION TERMINATION;

BACTERIOPHAGE T7; DNA ADDUCTS; DNA BREAKS, SINGLE-STRANDED; DNA REPAIR; DNA-DIRECTED RNA POLYMERASES; HELA CELLS; HUMANS; RNA POLYMERASE II; TRANSCRIPTION, GENETIC;

MAMMALIA;

EID: 84868580497     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301240y     Document Type: Article

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