메뉴 건너뛰기




Volumn 41, Issue 13, 2013, Pages 6421-6429

Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBOXYL 2' DEOXYCYTIDINE; 5 FORMYL 2' DEOXYCYTIDINE; 5 HYDROXYMETHYLDEOXYCYTIDINE; 5 HYDROXYMETHYLDEOXYURIDINE; 5 METHYLCYTOSINE; 5 METHYLDEOXYCYTIDINE; BIOLOGICAL MARKER; CARBOXYL GROUP; CELL DNA; CYTIDINE DERIVATIVE; CYTOSINE; GENOMIC DNA; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG;

EID: 84880554318     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt360     Document Type: Article
Times cited : (119)

References (34)
  • 1
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • DOI 10.1038/ng1089
    • Jaenisch, R. and Bird, A. (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet., 33, 245-254. (Pubitemid 36278835)
    • (2003) Nature Genetics , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 2
    • 0035839136 scopus 로고    scopus 로고
    • Translating the histone code
    • DOI 10.1126/science.1063127
    • Jenuwein, T. and Allis, C.D. (2001) Translating the histone code. Science, 293, 1074-1080. (Pubitemid 32758077)
    • (2001) Science , vol.293 , Issue.5532 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 3
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • DOI 10.1016/S0092-8674(00)81656-6
    • Okano, M., Bell, D.W., Haber, D.A. and Li, E. (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell, 99, 247-257. (Pubitemid 29519904)
    • (1999) Cell , vol.99 , Issue.3 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 4
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T.H. and Jaenisch, R. (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell, 69, 915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 5
    • 45449114804 scopus 로고    scopus 로고
    • The colorful history of active DNA demethylation
    • DOI 10.1016/j.cell.2008.06.009, PII S0092867408007617
    • Ooi, S.K. and Bestor, T.H. (2008) The colorful history of active DNA demethylation. Cell, 133, 1145-1148. (Pubitemid 351852922)
    • (2008) Cell , vol.133 , Issue.7 , pp. 1145-1148
    • Ooi, S.K.T.1    Bestor, T.H.2
  • 6
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: Many roads lead to rome
    • Wu, S.C. and Zhang, Y. (2010) Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell. Biol., 11, 607-620.
    • (2010) Nat. Rev. Mol. Cell. Biol. , vol.11 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 8
    • 77956189495 scopus 로고    scopus 로고
    • Role of tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito, S., D'Alessio, A.C., Taranova, O.V., Hong, K., Sowers, L.C. and Zhang, Y. (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature, 466, 1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 9
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
    • He, Y.F., Li, B.Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, L. et al. (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science, 333, 1303-1307.
    • (2011) Science , vol.333 , pp. 1303-1307
    • He, Y.F.1    Li, B.Z.2    Li, Z.3    Liu, P.4    Wang, Y.5    Tang, Q.6    Ding, J.7    Jia, Y.8    Chen, Z.9    Li, L.10
  • 10
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito, S., Shen, L., Dai, Q., Wu, S.C., Collins, L.B., Swenberg, J.A., He, C. and Zhang, Y. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science, 333, 1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5    Swenberg, J.A.6    He, C.7    Zhang, Y.8
  • 11
    • 80053917872 scopus 로고    scopus 로고
    • Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: Potential implications for active demethylation of CpG sites
    • Maiti, A. and Drohat, A.C. (2011) Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J. Biol. Chem., 286, 35334-35338.
    • (2011) J. Biol. Chem. , vol.286 , pp. 35334-35338
    • Maiti, A.1    Drohat, A.C.2
  • 12
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo, J.U., Su, Y., Zhong, C., Ming, G.L. and Song, H. (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell, 145, 423-434.
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 16
    • 4744344066 scopus 로고    scopus 로고
    • Epigenetics and cancer
    • DOI 10.1101/gad.1232504
    • Lund, A.H. and van Lohuizen, M. (2004) Epigenetics and cancer. Genes Dev., 18, 2315-2335. (Pubitemid 39310518)
    • (2004) Genes and Development , vol.18 , Issue.19 , pp. 2315-2335
    • Lund, A.H.1    Van Lohuizen, M.2
  • 17
    • 0037099537 scopus 로고    scopus 로고
    • LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23)
    • Ono, R., Taki, T., Taketani, T., Taniwaki, M., Kobayashi, H. and Hayashi, Y. (2002) LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res., 62, 4075-4080. (Pubitemid 34791077)
    • (2002) Cancer Research , vol.62 , Issue.14 , pp. 4075-4080
    • Ono, R.1    Taki, T.2    Taketani, T.3    Taniwaki, M.4    Kobayashi, H.5    Hayashi, Y.6
  • 18
    • 0037350661 scopus 로고    scopus 로고
    • TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;23) [3]
    • DOI 10.1038/sj.leu.2402834
    • Lorsbach, R.B., Moore, J., Mathew, S., Raimondi, S.C., Mukatira, S.T. and Downing, J.R. (2003) TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia, 17, 637-641. (Pubitemid 36395661)
    • (2003) Leukemia , vol.17 , Issue.3 , pp. 637-641
    • Lorsback, R.B.1    Moore, J.2    Mathew, S.3    Raimondi, S.C.4    Mukatira, S.T.5    Downing, J.R.6
  • 20
    • 84873411803 scopus 로고    scopus 로고
    • Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation
    • Yang, H., Liu, Y., Bai, F., Zhang, J.Y., Ma, S.H., Liu, J., Xu, Z.D., Zhu, H.G., Ling, Z.Q., Ye, D. et al. (2013) Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene, 32, 663-669.
    • (2013) Oncogene , vol.32 , pp. 663-669
    • Yang, H.1    Liu, Y.2    Bai, F.3    Zhang, J.Y.4    Ma, S.H.5    Liu, J.6    Xu, Z.D.7    Zhu, H.G.8    Ling, Z.Q.9    Ye, D.10
  • 21
    • 84255200412 scopus 로고    scopus 로고
    • 5-hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations
    • Jin, S.G., Jiang, Y., Qiu, R., Rauch, T.A., Wang, Y., Schackert, G., Krex, D., Lu, Q. and Pfeifer, G.P. (2011) 5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer Res., 71, 7360-7365.
    • (2011) Cancer Res. , vol.71 , pp. 7360-7365
    • Jin, S.G.1    Jiang, Y.2    Qiu, R.3    Rauch, T.A.4    Wang, Y.5    Schackert, G.6    Krex, D.7    Lu, Q.8    Pfeifer, G.P.9
  • 23
    • 33748956160 scopus 로고    scopus 로고
    • Collisionally Activated Dissociation of Protonated 2′- Deoxycytidine, 2′-Deoxyuridine, and their Oxidatively Damaged Derivatives
    • DOI 10.1016/j.jasms.2006.05.019, PII S1044030506005575
    • Cao, H. and Wang, Y. (2006) Collisionally activated dissociation of protonated 2'-deoxycytidine, 2'-deoxyuridine, and their oxidatively damaged derivatives. J. Am. Soc. Mass Spectrom., 17, 1335-1341. (Pubitemid 44441925)
    • (2006) Journal of the American Society for Mass Spectrometry , vol.17 , Issue.10 , pp. 1335-1341
    • Cao, H.1    Wang, Y.2
  • 24
    • 79959712131 scopus 로고    scopus 로고
    • Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA
    • Dai, Q. and He, C. (2011) Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA. Org. Lett., 13, 3446-3449.
    • (2011) Org. Lett. , vol.13 , pp. 3446-3449
    • Dai, Q.1    He, C.2
  • 25
    • 84864010124 scopus 로고    scopus 로고
    • The oxidative DNA lesions 8,5' -cyclopurines accumulate with aging in a tissue-specific manner
    • Wang, J., Clauson, C.L., Robbins, P.D., Niedernhofer, L.J. and Wang, Y. (2012) The oxidative DNA lesions 8,5' -cyclopurines accumulate with aging in a tissue-specific manner. Aging. Cell, 11, 714-716.
    • (2012) Aging. Cell , vol.11 , pp. 714-716
    • Wang, J.1    Clauson, C.L.2    Robbins, P.D.3    Niedernhofer, L.J.4    Wang, Y.5
  • 27
    • 84869084595 scopus 로고    scopus 로고
    • An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background
    • Mitra, D., Luo, X., Morgan, A., Wang, J., Hoang, M.P., Lo, J., Guerrero, C.R., Lennerz, J.K., Mihm, M.C., Wargo, J.A. et al. (2012) An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature, 491, 449-453.
    • (2012) Nature , vol.491 , pp. 449-453
    • Mitra, D.1    Luo, X.2    Morgan, A.3    Wang, J.4    Hoang, M.P.5    Lo, J.6    Guerrero, C.R.7    Lennerz, J.K.8    Mihm, M.C.9    Wargo, J.A.10
  • 28
    • 79952236603 scopus 로고    scopus 로고
    • 6-thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1
    • Yuan, B., Zhang, J., Wang, H., Xiong, L., Cai, Q., Wang, T., Jacobsen, S., Pradhan, S. and Wang, Y. (2011) 6-Thioguanine reactivates epigenetically silenced genes in acute lymphoblastic leukemia cells by facilitating proteasome-mediated degradation of DNMT1. Cancer Res., 71, 1904-1911.
    • (2011) Cancer Res. , vol.71 , pp. 1904-1911
    • Yuan, B.1    Zhang, J.2    Wang, H.3    Xiong, L.4    Cai, Q.5    Wang, T.6    Jacobsen, S.7    Pradhan, S.8    Wang, Y.9
  • 29
    • 81755166995 scopus 로고    scopus 로고
    • Cyclophosphamide perturbs cytosine methylation in jurkat-T cells through LSD1-mediated stabilization of DNMT1 protein
    • Zhang, J., Yuan, B., Zhang, F., Xiong, L., Wu, J., Pradhan, S. and Wang, Y. (2011) Cyclophosphamide perturbs cytosine methylation in Jurkat-T cells through LSD1-mediated stabilization of DNMT1 protein. Chem. Res. Toxicol., 24, 2040-2043.
    • (2011) Chem. Res. Toxicol. , vol.24 , pp. 2040-2043
    • Zhang, J.1    Yuan, B.2    Zhang, F.3    Xiong, L.4    Wu, J.5    Pradhan, S.6    Wang, Y.7
  • 30
    • 79954589295 scopus 로고    scopus 로고
    • Quantification of oxidative DNA lesions in tissues of long-evans cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method
    • Wang, J., Yuan, B., Guerrero, C., Bahde, R., Gupta, S. and Wang, Y. (2011) Quantification of oxidative DNA lesions in tissues of Long-Evans Cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method. Anal. Chem., 83, 2201-2209.
    • (2011) Anal. Chem. , vol.83 , pp. 2201-2209
    • Wang, J.1    Yuan, B.2    Guerrero, C.3    Bahde, R.4    Gupta, S.5    Wang, Y.6
  • 31
    • 34547927642 scopus 로고    scopus 로고
    • Quantification of oxidative single-base and intrastrand cross-link lesions in unmethylated and CpG-methylated DNA induced by Fenton-type reagents
    • DOI 10.1093/nar/gkm497
    • Cao, H. and Wang, Y. (2007) Quantification of oxidative singlebase and intrastrand cross-link lesions in unmethylated and CpG-methylated DNA induced by Fenton-type reagents. Nucleic Acids Res., 35, 4833-4844. (Pubitemid 47263393)
    • (2007) Nucleic Acids Research , vol.35 , Issue.14 , pp. 4833-4844
    • Cao, H.1    Wang, Y.2
  • 32
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in purkinje neurons and the brain
    • Kriaucionis, S. and Heintz, N. (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 324, 929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 33
    • 84862776719 scopus 로고    scopus 로고
    • Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine- modified DNA
    • Zhang, L., Lu, X., Lu, J., Liang, H., Dai, Q., Xu, G.L., Luo, C., Jiang, H. and He, C. (2012) Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat. Chem. Biol., 8, 328-330.
    • (2012) Nat. Chem. Biol. , vol.8 , pp. 328-330
    • Zhang, L.1    Lu, X.2    Lu, J.3    Liang, H.4    Dai, Q.5    Xu, G.L.6    Luo, C.7    Jiang, H.8    He, C.9
  • 34
    • 84455167621 scopus 로고    scopus 로고
    • Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
    • Yildirim, O., Li, R., Hung, J.H., Chen, P.B., Dong, X., Ee, L.S., Weng, Z., Rando, O.J. and Fazzio, T.G. (2011) Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell, 147, 1498-1510.
    • (2011) Cell , vol.147 , pp. 1498-1510
    • Yildirim, O.1    Li, R.2    Hung, J.H.3    Chen, P.B.4    Dong, X.5    Ee, L.S.6    Weng, Z.7    Rando, O.J.8    Fazzio, T.G.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.