-
1
-
-
84874258738
-
Structural advances for the major facilitator superfamily (MFS) transporters
-
Yan N. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem Sci 2013;38 (3): 151-159.
-
(2013)
Trends Biochem Sci
, vol.38
, Issue.3
, pp. 151-159
-
-
Yan, N.1
-
2
-
-
34547208011
-
Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues
-
Nigam SK, Bush KT, Bhatnagar V. Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues. Nat Clin Pract Nephrol 2007;3 (8):443-448.
-
(2007)
Nat Clin Pract Nephrol
, vol.3
, Issue.8
, pp. 443-448
-
-
Nigam, S.K.1
Bush, K.T.2
Bhatnagar, V.3
-
3
-
-
3042630508
-
Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters
-
Eraly SA, Monte JC, Nigam SK. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Physiol Genomics 2004;18 (1):12-24.
-
(2004)
Physiol Genomics
, vol.18
, Issue.1
, pp. 12-24
-
-
Eraly, S.A.1
Monte, J.C.2
Nigam, S.K.3
-
4
-
-
67650266683
-
Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members
-
Wu W, Baker ME, Eraly SA, Bush KT, Nigam SK. Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members. Physiol Genomics 2009;38 (2):116-124.
-
(2009)
Physiol Genomics
, vol.38
, Issue.2
, pp. 116-124
-
-
Wu, W.1
Baker, M.E.2
Eraly, S.A.3
Bush, K.T.4
Nigam, S.K.5
-
5
-
-
84875181483
-
The SLC22 family with transporters of organic cations, anions and zwitterions
-
Koepsell H. The SLC22 family with transporters of organic cations, anions and zwitterions. Mol Aspects Med 2013;34 (2-3):413-435.
-
(2013)
Mol Aspects Med
, vol.34
, Issue.2-3
, pp. 413-435
-
-
Koepsell, H.1
-
6
-
-
84875123211
-
The ABCs of membrane transporters in health and disease (SLC series): introduction
-
Hediger MA, Clemencon B, Burrier RE, Bruford EA. The ABCs of membrane transporters in health and disease (SLC series): introduction. Mol Aspects Med 2013;34 (2-3):95-107.
-
(2013)
Mol Aspects Med
, vol.34
, Issue.2-3
, pp. 95-107
-
-
Hediger, M.A.1
Clemencon, B.2
Burrier, R.E.3
Bruford, E.A.4
-
7
-
-
48749084010
-
Physiology, structure, and regulation of the cloned organic anion transporters
-
Srimaroeng C, Perry JL, Pritchard JB. Physiology, structure, and regulation of the cloned organic anion transporters. Xenobiotica 2008;38 (7-8):889-935.
-
(2008)
Xenobiotica
, vol.38
, Issue.7-8
, pp. 889-935
-
-
Srimaroeng, C.1
Perry, J.L.2
Pritchard, J.B.3
-
8
-
-
0028285029
-
Molecular cloning and characterization of a novel liver-specific transport protein
-
Simonson G, Vincent A, Roberg K, Huang Y, Iwanij V. Molecular cloning and characterization of a novel liver-specific transport protein. J Cell Sci 1994;107 (4):1065-1072.
-
(1994)
J Cell Sci
, vol.107
, Issue.4
, pp. 1065-1072
-
-
Simonson, G.1
Vincent, A.2
Roberg, K.3
Huang, Y.4
Iwanij, V.5
-
9
-
-
17144449057
-
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver
-
Sekine T, Cha SH, Tsuda M, Apiwattanakul N, Nakajima N, Kanai Y, Endou H. Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett 1998;429 (2):179-182.
-
(1998)
FEBS Lett
, vol.429
, Issue.2
, pp. 179-182
-
-
Sekine, T.1
Cha, S.H.2
Tsuda, M.3
Apiwattanakul, N.4
Nakajima, N.5
Kanai, Y.6
Endou, H.7
-
10
-
-
43049136807
-
NKT cDNA sequence, Gen Bank Accession Number: MMU52842
-
submitted March 27, 1996
-
Lopez-Nieto CE. 1996. NKT cDNA sequence, Gen Bank Accession Number: MMU52842, submitted March 27, 1996.
-
(1996)
-
-
Lopez-nieto, C.E.1
-
11
-
-
1342338182
-
Molecular cloning and characterization of a novel transport protein with very high expression in the kidney (Abstract)
-
Lopez-Nieto CE, You G, Barros EJG, Beier DR, Nigam SK. Molecular cloning and characterization of a novel transport protein with very high expression in the kidney (Abstract). J Am Soc Nephrol 1996;7:1301.
-
(1996)
J Am Soc Nephrol
, vol.7
, pp. 1301
-
-
Lopez-nieto, C.E.1
You, G.2
Barros, E.J.G.3
Beier, D.R.4
Nigam, S.K.5
-
12
-
-
0030940999
-
Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney
-
Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK. Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. J Biol Chem 1997;272 (10):6471-6478.
-
(1997)
J Biol Chem
, vol.272
, Issue.10
, pp. 6471-6478
-
-
Lopez-nieto, C.E.1
You, G.2
Bush, K.T.3
Barros, E.J.4
Beier, D.R.5
Nigam, S.K.6
-
13
-
-
0030855487
-
Expression cloning and characterization of a novel multispecific organic anion transporter
-
Sekine T, Watanabe N, Hosoyamada M, Kanai Y, Endou H. Expression cloning and characterization of a novel multispecific organic anion transporter. J Biol Chem 1997;272 (30):18526-18529.
-
(1997)
J Biol Chem
, vol.272
, Issue.30
, pp. 18526-18529
-
-
Sekine, T.1
Watanabe, N.2
Hosoyamada, M.3
Kanai, Y.4
Endou, H.5
-
14
-
-
0030781076
-
Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney
-
Sweet DH, Wolff NA, Pritchard JB. Expression cloning and characterization of ROAT1. The basolateral organic anion transporter in rat kidney. J Biol Chem 1997;272 (48):30088-30095.
-
(1997)
J Biol Chem
, vol.272
, Issue.48
, pp. 30088-30095
-
-
Sweet, D.H.1
Wolff, N.A.2
Pritchard, J.B.3
-
15
-
-
0034004157
-
Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct
-
Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK. Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol 2000;278 (4):F635-F643.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
, Issue.4
, pp. F635-F643
-
-
Pavlova, A.1
Sakurai, H.2
Leclercq, B.3
Beier, D.R.4
Yu, A.S.5
Nigam, S.K.6
-
16
-
-
71449118407
-
Interaction of organic cations with organic anion transporters
-
Ahn SY, Eraly SA, Tsigelny I, Nigam SK. Interaction of organic cations with organic anion transporters. J Biol Chem 2009;284 (45):31422-31430.
-
(2009)
J Biol Chem
, vol.284
, Issue.45
, pp. 31422-31430
-
-
Ahn, S.Y.1
Eraly, S.A.2
Tsigelny, I.3
Nigam, S.K.4
-
17
-
-
80052406750
-
Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis
-
Ahn SY, Jamshidi N, Mo ML, Wu W, Eraly SA, Dnyanmote A, Bush KT, Gallegos TF, Sweet DH, Palsson BO, Nigam SK. Linkage of organic anion transporter-1 to metabolic pathways through integrated "omics"-driven network and functional analysis. J Biol Chem 2011;286 (36):31522-31531.
-
(2011)
J Biol Chem
, vol.286
, Issue.36
, pp. 31522-31531
-
-
Ahn, S.Y.1
Jamshidi, N.2
Mo, M.L.3
Wu, W.4
Eraly, S.A.5
Dnyanmote, A.6
Bush, K.T.7
Gallegos, T.F.8
Sweet, D.H.9
Palsson, B.O.10
Nigam, S.K.11
-
18
-
-
84861152254
-
A role for the organic anion transporter OAT3 in renal creatinine secretion in mice
-
Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. Am J Physiol Renal Physiol 2012;302 (10):F1293-F1299.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, Issue.10
, pp. F1293-F1299
-
-
Vallon, V.1
Eraly, S.A.2
Rao, S.R.3
Gerasimova, M.4
Rose, M.5
Nagle, M.6
Anzai, N.7
Smith, T.8
Sharma, K.9
Nigam, S.K.10
Rieg, T.11
-
19
-
-
0033559052
-
A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse
-
Brady KP, Dushkin H, Fornzler D, Koike T, Magner F, Her H, Gullans S, Segre GV, Green RM, Beier DR. A novel putative transporter maps to the osteosclerosis (oc) mutation and is not expressed in the oc mutant mouse. Genomics 1999;56 (3):254-261.
-
(1999)
Genomics
, vol.56
, Issue.3
, pp. 254-261
-
-
Brady, K.P.1
Dushkin, H.2
Fornzler, D.3
Koike, T.4
Magner, F.5
Her, H.6
Gullans, S.7
Segre, G.V.8
Green, R.M.9
Beier, D.R.10
-
20
-
-
0033532065
-
Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain
-
Kusuhara H, Sekine T, Utsunomiya-Tate N, Tsuda M, Kojima R, Cha SH, Sugiyama Y, Kanai Y, Endou H. Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain. J Biol Chem 1999;274 (19):13675-13680.
-
(1999)
J Biol Chem
, vol.274
, Issue.19
, pp. 13675-13680
-
-
Kusuhara, H.1
Sekine, T.2
Utsunomiya-tate, N.3
Tsuda, M.4
Kojima, R.5
Cha, S.H.6
Sugiyama, Y.7
Kanai, Y.8
Endou, H.9
-
21
-
-
0033574034
-
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3)
-
Race JE, Grassl SM, Williams WJ, Holtzman EJ. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun 1999;255 (2):508-514.
-
(1999)
Biochem Biophys Res Commun
, vol.255
, Issue.2
, pp. 508-514
-
-
Race, J.E.1
Grassl, S.M.2
Williams, W.J.3
Holtzman, E.J.4
-
22
-
-
0000518648
-
Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta
-
Cha SH, Sekine T, Kusuhara H, Yu E, Kim JY, Kim DK, Sugiyama Y, Kanai Y, Endou H. Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta. J Biol Chem 2000;275 (6):4507-4512.
-
(2000)
J Biol Chem
, vol.275
, Issue.6
, pp. 4507-4512
-
-
Cha, S.H.1
Sekine, T.2
Kusuhara, H.3
Yu, E.4
Kim, J.Y.5
Kim, D.K.6
Sugiyama, Y.7
Kanai, Y.8
Endou, H.9
-
23
-
-
3242707822
-
Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney
-
Youngblood GL, Sweet DH. Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. Am J Physiol Renal Physiol 2004;287 (2):F236-F244.
-
(2004)
Am J Physiol Renal Physiol
, vol.287
, Issue.2
, pp. F236-F244
-
-
Youngblood, G.L.1
Sweet, D.H.2
-
24
-
-
4544322271
-
Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa
-
Monte JC, Nagle MA, Eraly SA, Nigam SK. Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa. Biochem Biophys Res Commun 2004;323 (2):429-436.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, Issue.2
, pp. 429-436
-
-
Monte, J.C.1
Nagle, M.A.2
Eraly, S.A.3
Nigam, S.K.4
-
25
-
-
0034817065
-
Isolation of a family of organic anion transporters from human liver and kidney
-
Sun W, Wu RR, van Poelje PD, Erion MD. Isolation of a family of organic anion transporters from human liver and kidney. Biochem Biophys Res Commun 2001;283 (2):417-422.
-
(2001)
Biochem Biophys Res Commun
, vol.283
, Issue.2
, pp. 417-422
-
-
Sun, W.1
Wu, R.R.2
van Poelje, P.D.3
Erion, M.D.4
-
26
-
-
34247400616
-
Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate
-
Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y. Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate. Hepatology 2007;45 (4):1046-1055.
-
(2007)
Hepatology
, vol.45
, Issue.4
, pp. 1046-1055
-
-
Shin, H.J.1
Anzai, N.2
Enomoto, A.3
He, X.4
Kim do, K.5
Endou, H.6
Kanai, Y.7
-
27
-
-
0032549690
-
Molecular cloning and characterization of two novel transport proteins from rat kidney
-
Schomig E, Spitzenberger F, Engelhardt M, Martel F, Ording N, Grundemann D. Molecular cloning and characterization of two novel transport proteins from rat kidney. FEBS Lett 1998;425 (1):79-86.
-
(1998)
FEBS Lett
, vol.425
, Issue.1
, pp. 79-86
-
-
Schomig, E.1
Spitzenberger, F.2
Engelhardt, M.3
Martel, F.4
Ording, N.5
Grundemann, D.6
-
28
-
-
42549088613
-
Functional and immunochemical characterization of a novel organic anion transporter Oat8 (Slc22a9) in rat renal collecting duct
-
Yokoyama H, Anzai N, Ljubojevic M, Ohtsu N, Sakata T, Miyazaki H, Nonoguchi H, Islam R, Onozato M, Tojo A, Tomita K, Kanai Y, Igarashi T, Sabolic I, Endou H. Functional and immunochemical characterization of a novel organic anion transporter Oat8 (Slc22a9) in rat renal collecting duct. Cell Physiol Biochem 2008;21 (4):269-278.
-
(2008)
Cell Physiol Biochem
, vol.21
, Issue.4
, pp. 269-278
-
-
Yokoyama, H.1
Anzai, N.2
Ljubojevic, M.3
Ohtsu, N.4
Sakata, T.5
Miyazaki, H.6
Nonoguchi, H.7
Islam, R.8
Onozato, M.9
Tojo, A.10
Tomita, K.11
Kanai, Y.12
Igarashi, T.13
Sabolic, I.14
Endou, H.15
-
29
-
-
77949922736
-
Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney
-
Tsuchida H, Anzai N, Shin HJ, Wempe MF, Jutabha P, Enomoto A, Cha SH, Satoh T, Ishida M, Sakurai H, Endou H. Identification of a novel organic anion transporter mediating carnitine transport in mouse liver and kidney. Cell Physiol Biochem 2010;25 (4-5):511-522.
-
(2010)
Cell Physiol Biochem
, vol.25
, Issue.4-5
, pp. 511-522
-
-
Tsuchida, H.1
Anzai, N.2
Shin, H.J.3
Wempe, M.F.4
Jutabha, P.5
Enomoto, A.6
Cha, S.H.7
Satoh, T.8
Ishida, M.9
Sakurai, H.10
Endou, H.11
-
30
-
-
0032469687
-
Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organiccation transporters
-
Nishiwaki T, Daigo Y, Tamari M, Fujii Y, Nakamura Y. Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organiccation transporters. Cytogenet Cell Genet 1998;83 (3-4):251-255.
-
(1998)
Cytogenet Cell Genet
, vol.83
, Issue.3-4
, pp. 251-255
-
-
Nishiwaki, T.1
Daigo, Y.2
Tamari, M.3
Fujii, Y.4
Nakamura, Y.5
-
31
-
-
47749112096
-
Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)
-
Bahn A, Hagos Y, Reuter S, Balen D, Brzica H, Krick W, Burckhardt BC, Sabolic I, Burckhardt G. Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). J Biol Chem 2008;283 (24):16332-16341.
-
(2008)
J Biol Chem
, vol.283
, Issue.24
, pp. 16332-16341
-
-
Bahn, A.1
Hagos, Y.2
Reuter, S.3
Balen, D.4
Brzica, H.5
Krick, W.6
Burckhardt, B.C.7
Sabolic, I.8
Burckhardt, G.9
-
32
-
-
0030772953
-
Kidneyspecific expression of a novel mouse organic cation transporterlike protein
-
Mori K, Ogawa Y, Ebihara K, Aoki T, Tamura N, Sugawara A, Kuwahara T, Ozaki S, Mukoyama M, Tashiro K. Kidneyspecific expression of a novel mouse organic cation transporterlike protein. FEBS Lett 1997;417 (3):371-374.
-
(1997)
FEBS Lett
, vol.417
, Issue.3
, pp. 371-374
-
-
Mori, K.1
Ogawa, Y.2
Ebihara, K.3
Aoki, T.4
Tamura, N.5
Sugawara, A.6
Kuwahara, T.7
Ozaki, S.8
Mukoyama, M.9
Tashiro, K.10
-
33
-
-
0037161834
-
Molecular identification of a renal urate anion exchanger that regulates blood urate levels
-
Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H. Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 2002;417 (6887):447-452.
-
(2002)
Nature
, vol.417
, Issue.6887
, pp. 447-452
-
-
Enomoto, A.1
Kimura, H.2
Chairoungdua, A.3
Shigeta, Y.4
Jutabha, P.5
Cha, S.H.6
Hosoyamada, M.7
Takeda, M.8
Sekine, T.9
Igarashi, T.10
Matsuo, H.11
Kikuchi, Y.12
Oda, T.13
Ichida, K.14
Hosoya, T.15
Shimokata, K.16
Niwa, T.17
Kanai, Y.18
Endou, H.19
-
34
-
-
84871983440
-
Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease
-
Wang L, Sweet DH. Renal organic anion transporters (SLC22 family): expression, regulation, roles in toxicity, and impact on injury and disease. AAPS J. 2013;15 (1):53-69.
-
(2013)
AAPS J
, vol.15
, Issue.1
, pp. 53-69
-
-
Wang, L.1
Sweet, D.H.2
-
35
-
-
35548966750
-
Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family
-
Jacobsson JA, Haitina T, Lindblom J, Fredriksson R. Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Genomics 2007;90 (5):595-609.
-
(2007)
Genomics
, vol.90
, Issue.5
, pp. 595-609
-
-
Jacobsson, J.A.1
Haitina, T.2
Lindblom, J.3
Fredriksson, R.4
-
36
-
-
69549103730
-
Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis
-
Ahn SY, Nigam SK. Toward a systems level understanding of organic anion and other multispecific drug transporters: a remote sensing and signaling hypothesis. Mol Pharmacol 2009;76 (3):481-490.
-
(2009)
Mol Pharmacol
, vol.76
, Issue.3
, pp. 481-490
-
-
Ahn, S.Y.1
Nigam, S.K.2
-
37
-
-
1342287145
-
The molecular pharmacology of organic anion transporters: from DNA to FDA?
-
Eraly SA, Bush KT, Sampogna RV, Bhatnagar V, Nigam SK. The molecular pharmacology of organic anion transporters: from DNA to FDA? Mol Pharmacol 2004;65 (3):479-487.
-
(2004)
Mol Pharmacol
, vol.65
, Issue.3
, pp. 479-487
-
-
Eraly, S.A.1
Bush, K.T.2
Sampogna, R.V.3
Bhatnagar, V.4
Nigam, S.K.5
-
38
-
-
0037427506
-
Organic anion and cation transporters occur in pairs of similar and similarly expressed genes
-
Eraly SA, Hamilton BA, Nigam SK. Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochem Biophys Res Commun 2003;300 (2):333-342.
-
(2003)
Biochem Biophys Res Commun
, vol.300
, Issue.2
, pp. 333-342
-
-
Eraly, S.A.1
Hamilton, B.A.2
Nigam, S.K.3
-
39
-
-
79954998791
-
Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis
-
Wu W, Dnyanmote AV, Nigam SK. Remote communication through solute carriers and ATP binding cassette drug transporter pathways: an update on the remote sensing and signaling hypothesis. Mol Pharmacol 2011;79 (5):795-805.
-
(2011)
Mol Pharmacol
, vol.79
, Issue.5
, pp. 795-805
-
-
Wu, W.1
Dnyanmote, A.V.2
Nigam, S.K.3
-
40
-
-
84865578333
-
Drug transport by Organic Anion Transporters (OATs)
-
Burckhardt G. Drug transport by Organic Anion Transporters (OATs). Pharmacol Ther 2012;136 (1):106-130.
-
(2012)
Pharmacol Ther
, vol.136
, Issue.1
, pp. 106-130
-
-
Burckhardt, G.1
-
41
-
-
0346654145
-
The molecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules
-
Dantzler WH, Wright SH. The molecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules. Biochim Biophys Acta 2003;1618 (2):185-193.
-
(2003)
Biochim Biophys Acta
, vol.1618
, Issue.2
, pp. 185-193
-
-
Dantzler, W.H.1
Wright, S.H.2
-
42
-
-
0029902695
-
Renal secretion of organic anions and cations
-
Pritchard JB, Miller DS. Renal secretion of organic anions and cations. Kidney Int 1996;49 (6):1649-1654.
-
(1996)
Kidney Int
, vol.49
, Issue.6
, pp. 1649-1654
-
-
Pritchard, J.B.1
Miller, D.S.2
-
43
-
-
33845446759
-
Molecular insights into the structure-function relationship of organic anion transporters OATs
-
Zhou F, You G. Molecular insights into the structure-function relationship of organic anion transporters OATs. Pharm Res 2007;24 (1):28-36.
-
(2007)
Pharm Res
, vol.24
, Issue.1
, pp. 28-36
-
-
Zhou, F.1
You, G.2
-
44
-
-
0035826582
-
Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3
-
Feng B, Dresser MJ, Shu Y, Johns SJ, Giacomini KM. Arginine 454 and lysine 370 are essential for the anion specificity of the organic anion transporter, rOAT3. Biochemistry 2001;40 (18):5511-5520.
-
(2001)
Biochemistry
, vol.40
, Issue.18
, pp. 5511-5520
-
-
Feng, B.1
Dresser, M.J.2
Shu, Y.3
Johns, S.J.4
Giacomini, K.M.5
-
45
-
-
79961135233
-
Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3)
-
Astorga B, Wunz TM, Morales M, Wright SH, Pelis RM. Differences in the substrate binding regions of renal organic anion transporters 1 (OAT1) and 3 (OAT3). Am J Physiol Renal Physiol 2011;301 (2):F378-F386.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, Issue.2
, pp. F378-F386
-
-
Astorga, B.1
Wunz, T.M.2
Morales, M.3
Wright, S.H.4
Pelis, R.M.5
-
46
-
-
33846010171
-
A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport
-
Perry JL, Dembla-Rajpal N, Hall LA, Pritchard JB. A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport. J Biol Chem 2006;281 (49):38071-38079.
-
(2006)
J Biol Chem
, vol.281
, Issue.49
, pp. 38071-38079
-
-
Perry, J.L.1
Dembla-rajpal, N.2
Hall, L.A.3
Pritchard, J.B.4
-
47
-
-
80955151668
-
Conformational Changes of the Multispecific Transporter Organic Anion Transporter 1 (OAT1/SLC22A6) Suggests a Molecular Mechanism for Initial Stages of Drug and Metabolite Transport
-
Tsigelny IF, Kovalskyy D, Kouznetsova VL, Balinskyi O, Sharikov Y, Bhatnagar V, Nigam SK. Conformational Changes of the Multispecific Transporter Organic Anion Transporter 1 (OAT1/SLC22A6) Suggests a Molecular Mechanism for Initial Stages of Drug and Metabolite Transport. Cell Biochem Biophys 2011;61 (2):251-259.
-
(2011)
Cell Biochem Biophys
, vol.61
, Issue.2
, pp. 251-259
-
-
Tsigelny, I.F.1
Kovalskyy, D.2
Kouznetsova, V.L.3
Balinskyi, O.4
Sharikov, Y.5
Bhatnagar, V.6
Nigam, S.K.7
-
48
-
-
78649665012
-
In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy
-
Fromm MF, Kim RB, editors, Berlin, Heidelberg: Springer
-
Burckhardt G, Burckhardt BC. In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy. In: Fromm MF, Kim RB, editors. Drug Transporters. Berlin, Heidelberg: Springer; 2011. p 29-104.
-
(2011)
Drug Transporters
, pp. 29-104
-
-
Burckhardt, G.1
Burckhardt, B.C.2
-
49
-
-
75349105185
-
Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology
-
Van Wert AL, Gionfriddo MR, Sweet DH. Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology. Biopharm Drug Dispos 2010;31 (1):1-71.
-
(2010)
Biopharm Drug Dispos
, vol.31
, Issue.1
, pp. 1-71
-
-
Van Wert, A.L.1
Gionfriddo, M.R.2
Sweet, D.H.3
-
50
-
-
33750821441
-
Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions
-
Kaler G, Truong DM, Sweeney DE, Logan DW, Nagle M, Wu W, Eraly SA, Nigam SK. Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. Biochem Biophys Res Commun 2006;351 (4):872-876.
-
(2006)
Biochem Biophys Res Commun
, vol.351
, Issue.4
, pp. 872-876
-
-
Kaler, G.1
Truong, D.M.2
Sweeney, D.E.3
Logan, D.W.4
Nagle, M.5
Wu, W.6
Eraly, S.A.7
Nigam, S.K.8
-
51
-
-
84879397236
-
How Much Do We Know About Drug Handling by SLC and ABC Drug Transporters in Children?
-
Nigam SK, Bhatnagar V. How Much Do We Know About Drug Handling by SLC and ABC Drug Transporters in Children? Clin Pharmacol Ther 2013;94 (1):27-29.
-
(2013)
Clin Pharmacol Ther
, vol.94
, Issue.1
, pp. 27-29
-
-
Nigam, S.K.1
Bhatnagar, V.2
-
52
-
-
33644499212
-
Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models
-
Sweet DH, Eraly SA, Vaughn DA, Bush KT, Nigam SK. Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney Int 2006;69 (5):837-845.
-
(2006)
Kidney Int
, vol.69
, Issue.5
, pp. 837-845
-
-
Sweet, D.H.1
Eraly, S.A.2
Vaughn, D.A.3
Bush, K.T.4
Nigam, S.K.5
-
53
-
-
79959313678
-
Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney
-
Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney. Mol Pharmacol 2011;80 (1):147-154.
-
(2011)
Mol Pharmacol
, vol.80
, Issue.1
, pp. 147-154
-
-
Sweeney, D.E.1
Vallon, V.2
Rieg, T.3
Wu, W.4
Gallegos, T.F.5
Nigam, S.K.6
-
54
-
-
85153809002
-
Developmental aspects of organic acid transport
-
Polin RA, Fox WW, Abman SH, editors, Philadelphia: Saunders
-
Jones DP, Stapleton FB. Developmental aspects of organic acid transport. In: Polin RA, Fox WW, Abman SH, editors. Fetal and Neonatal Physiology. Philadelphia: Saunders; 2011. p 1388-1392.
-
(2011)
Fetal and Neonatal Physiology
, pp. 1388-1392
-
-
Jones, D.P.1
Stapleton, F.B.2
-
55
-
-
84859970418
-
Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6
-
Wegner W, Burckhardt BC, Burckhardt G, Henjakovic M. Male-dominant activation of rat renal organic anion transporter 1 (Oat1) and 3 (Oat3) expression by transcription factor BCL6. PLoS One 2012;7 (4):e35556.
-
(2012)
PLoS One
, vol.7
, Issue.4
, pp. e35556
-
-
Wegner, W.1
Burckhardt, B.C.2
Burckhardt, G.3
Henjakovic, M.4
-
56
-
-
73649124171
-
The role of peroxisome proliferator-activated receptor alpha in transcriptional regulation of novel organic cation transporters
-
Eder K, Ringseis R. The role of peroxisome proliferator-activated receptor alpha in transcriptional regulation of novel organic cation transporters. Eur J Pharmacol 2010;628 (1-3):1-5.
-
(2010)
Eur J Pharmacol
, vol.628
, Issue.1-3
, pp. 1-5
-
-
Eder, K.1
Ringseis, R.2
-
57
-
-
84863750420
-
Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule
-
Gallegos TF, Martovetsky G, Kouznetsova V, Bush KT, Nigam SK. Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule. PLoS One 2012;7 (7):e40796.
-
(2012)
PLoS One
, vol.7
, Issue.7
, pp. e40796
-
-
Gallegos, T.F.1
Martovetsky, G.2
Kouznetsova, V.3
Bush, K.T.4
Nigam, S.K.5
-
58
-
-
84888404447
-
Hepatocyte nuclear factors 4{alpha} and 1{alpha} regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters
-
Martovetsky G, Tee JB, Nigam SK. Hepatocyte nuclear factors 4{alpha} and 1{alpha} regulate kidney developmental expression of drug-metabolizing enzymes and drug transporters. Mol Pharmacol 2013;84 (6):808-823.
-
(2013)
Mol Pharmacol
, vol.84
, Issue.6
, pp. 808-823
-
-
Martovetsky, G.1
Tee, J.B.2
Nigam, S.K.3
-
59
-
-
79960615869
-
Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats
-
Naud J, Michaud J, Beauchemin S, Hebert MJ, Roger M, Lefrancois S, Leblond FA, Pichette V. Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats. Drug Metab Dispos 2011;39 (8):1363-1369.
-
(2011)
Drug Metab Dispos
, vol.39
, Issue.8
, pp. 1363-1369
-
-
Naud, J.1
Michaud, J.2
Beauchemin, S.3
Hebert, M.J.4
Roger, M.5
Lefrancois, S.6
Leblond, F.A.7
Pichette, V.8
-
60
-
-
70349618596
-
Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride
-
Di Giusto G, Anzai N, Ruiz ML, Endou H, Torres AM. Expression and function of Oat1 and Oat3 in rat kidney exposed to mercuric chloride. Arch Toxicol 2009;83 (10):887-897.
-
(2009)
Arch Toxicol
, vol.83
, Issue.10
, pp. 887-897
-
-
Di Giusto, G.1
Anzai, N.2
Ruiz, M.L.3
Endou, H.4
Torres, A.M.5
-
61
-
-
72049089059
-
Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: pharmacological and toxicological implications
-
Saito H. Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: pharmacological and toxicological implications. Pharmacol Ther 2010;125 (1):79-91.
-
(2010)
Pharmacol Ther
, vol.125
, Issue.1
, pp. 79-91
-
-
Saito, H.1
-
62
-
-
84867010904
-
Evaluation of chineseherbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1
-
Lin CC, Fan HY, Kuo CW, Pao LH. Evaluation of chineseherbal-medicine-induced herb-drug interactions: focusing on organic anion transporter 1. Evid Based Complement Alternat Med 2012;2012:967182.
-
(2012)
Evid Based Complement Alternat Med
, vol.2012
, pp. 967182
-
-
Lin, C.C.1
Fan, H.Y.2
Kuo, C.W.3
Pao, L.H.4
-
63
-
-
84862494884
-
Short-term and long-term effects of protein kinase C on the trafficking and stability of human organic anion transporter 3
-
Zhang Q, Suh W, Pan Z, You G. Short-term and long-term effects of protein kinase C on the trafficking and stability of human organic anion transporter 3. Int J Biochem Mol Biol 2012;3 (2):242-249.
-
(2012)
Int J Biochem Mol Biol
, vol.3
, Issue.2
, pp. 242-249
-
-
Zhang, Q.1
Suh, W.2
Pan, Z.3
You, G.4
-
64
-
-
84871545704
-
Lysine 48-linked polyubiquitination of organic anion transporter-1 is essential for its protein kinase C-regulated endocytosis
-
Zhang Q, Li S, Patterson C, You G. Lysine 48-linked polyubiquitination of organic anion transporter-1 is essential for its protein kinase C-regulated endocytosis. Mol Pharmacol 2013;83 (1):217-224.
-
(2013)
Mol Pharmacol
, vol.83
, Issue.1
, pp. 217-224
-
-
Zhang, Q.1
Li, S.2
Patterson, C.3
You, G.4
-
65
-
-
84868583572
-
Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization
-
Duan P, Li S, Ai N, Hu L, Welsh WJ, You G. Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization. Mol Pharm 2012;9 (11):3340-3346.
-
(2012)
Mol Pharm
, vol.9
, Issue.11
, pp. 3340-3346
-
-
Duan, P.1
Li, S.2
Ai, N.3
Hu, L.4
Welsh, W.J.5
You, G.6
-
66
-
-
84876456178
-
Regulation of renal organic anion transporter 3 (SLC22A8) expression and function by the integrity of lipid raft domains and their associated cytoskeleton
-
Srimaroeng C, Cecile JP, Walden R, Pritchard JB. Regulation of renal organic anion transporter 3 (SLC22A8) expression and function by the integrity of lipid raft domains and their associated cytoskeleton. Cell Physiol Biochem 2013;31 (4-5):565-578.
-
(2013)
Cell Physiol Biochem
, vol.31
, Issue.4-5
, pp. 565-578
-
-
Srimaroeng, C.1
Cecile, J.P.2
Walden, R.3
Pritchard, J.B.4
-
67
-
-
33645909146
-
Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins
-
Miyazaki H, Anzai N, Ekaratanawong S, Sakata T, Shin HJ, Jutabha P, Hirata T, He X, Nonoguchi H, Tomita K, Kanai Y, Endou H. Modulation of renal apical organic anion transporter 4 function by two PDZ domain-containing proteins. J Am Soc Nephrol 2005;16 (12):3498-3506.
-
(2005)
J Am Soc Nephrol
, vol.16
, Issue.12
, pp. 3498-3506
-
-
Miyazaki, H.1
Anzai, N.2
Ekaratanawong, S.3
Sakata, T.4
Shin, H.J.5
Jutabha, P.6
Hirata, T.7
He, X.8
Nonoguchi, H.9
Tomita, K.10
Kanai, Y.11
Endou, H.12
-
68
-
-
46749102824
-
Urate transport across the apical membrane of renal proximal tubules
-
Endou H, Anzai N. Urate transport across the apical membrane of renal proximal tubules. Nucleosides Nucleotides Nucleic Acids 2008;27 (6):578-584.
-
(2008)
Nucleosides Nucleotides Nucleic Acids
, vol.27
, Issue.6
, pp. 578-584
-
-
Endou, H.1
Anzai, N.2
-
69
-
-
77953150150
-
Regulation of human organic anion transporter 4 by protein kinase C and NHERF-1: altering the endocytosis of the transporter
-
Zhang Q, Pan Z, You G. Regulation of human organic anion transporter 4 by protein kinase C and NHERF-1: altering the endocytosis of the transporter. Pharm Res 2010;27 (4):589-596.
-
(2010)
Pharm Res
, vol.27
, Issue.4
, pp. 589-596
-
-
Zhang, Q.1
Pan, Z.2
You, G.3
-
70
-
-
84930483089
-
Organic anion transporters and their implications in pharmacotherapy
-
Emami Riedmaier A, Nies AT, Schaeffeler E, Schwab M. Organic anion transporters and their implications in pharmacotherapy. Pharmacol Rev 2012;64 (3):421-449.
-
(2012)
Pharmacol Rev
, vol.64
, Issue.3
, pp. 421-449
-
-
Emami Riedmaier, A.1
Nies, A.T.2
Schaeffeler, E.3
Schwab, M.4
-
71
-
-
33646165531
-
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice
-
Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem 2006;281 (8):5072-5083.
-
(2006)
J Biol Chem
, vol.281
, Issue.8
, pp. 5072-5083
-
-
Eraly, S.A.1
Vallon, V.2
Vaughn, D.A.3
Gangoiti, J.A.4
Richter, K.5
Nagle, M.6
Monte, J.C.7
Rieg, T.8
Truong, D.M.9
Long, J.M.10
Barshop, B.A.11
Kaler, G.12
Nigam, S.K.13
-
72
-
-
54749112371
-
Organic anion transporter 3 contributes to the regulation of blood pressure
-
Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. J Am Soc Nephrol 2008;19 (9):1732-1740.
-
(2008)
J Am Soc Nephrol
, vol.19
, Issue.9
, pp. 1732-1740
-
-
Vallon, V.1
Eraly, S.A.2
Wikoff, W.R.3
Rieg, T.4
Kaler, G.5
Truong, D.M.6
Ahn, S.Y.7
Mahapatra, N.R.8
Mahata, S.K.9
Gangoiti, J.A.10
Wu, W.11
Barshop, B.A.12
Siuzdak, G.13
Nigam, S.K.14
-
73
-
-
44949088665
-
Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics
-
Vallon V, Rieg T, Ahn SY, Wu W, Eraly SA, Nigam SK. Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics. Am J Physiol Renal Physiol 2008;294 (4):F867-F873.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, Issue.4
, pp. F867-F873
-
-
Vallon, V.1
Rieg, T.2
Ahn, S.Y.3
Wu, W.4
Eraly, S.A.5
Nigam, S.K.6
-
74
-
-
78650936423
-
Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling
-
Nagle MA, Truong DM, Dnyanmote AV, Ahn SY, Eraly SA, Wu W, Nigam SK. Analysis of three-dimensional systems for developing and mature kidneys clarifies the role of OAT1 and OAT3 in antiviral handling. J Biol Chem 2011;286 (1):243-251.
-
(2011)
J Biol Chem
, vol.286
, Issue.1
, pp. 243-251
-
-
Nagle, M.A.1
Truong, D.M.2
Dnyanmote, A.V.3
Ahn, S.Y.4
Eraly, S.A.5
Wu, W.6
Nigam, S.K.7
-
75
-
-
84873059003
-
Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue
-
Nagle MA, Wu W, Eraly SA, Nigam SK. Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue. Neurosci Lett 2013;534:133-138.
-
(2013)
Neurosci Lett
, vol.534
, pp. 133-138
-
-
Nagle, M.A.1
Wu, W.2
Eraly, S.A.3
Nigam, S.K.4
-
76
-
-
43749115381
-
Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination
-
Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK. Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. J Biol Chem 2008;283 (13):8654-8663.
-
(2008)
J Biol Chem
, vol.283
, Issue.13
, pp. 8654-8663
-
-
Truong, D.M.1
Kaler, G.2
Khandelwal, A.3
Swaan, P.W.4
Nigam, S.K.5
-
77
-
-
35348889668
-
Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G
-
Vanwert AL, Bailey RM, Sweet DH. Organic anion transporter 3 (Oat3/Slc22a8) knockout mice exhibit altered clearance and distribution of penicillin G. Am J Physiol Renal Physiol 2007; 293 (4):F1332-F1341.
-
(2007)
Am J Physiol Renal Physiol
, vol.293
, Issue.4
, pp. F1332-F1341
-
-
Vanwert, A.L.1
Bailey, R.M.2
Sweet, D.H.3
-
78
-
-
39149106149
-
Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates
-
Van Wert AL, Sweet DH. Impaired clearance of methotrexate in organic anion transporter 3 (Slc22a8) knockout mice: a gender specific impact of reduced folates. Pharm Res 2008;25 (2):453-462.
-
(2008)
Pharm Res
, vol.25
, Issue.2
, pp. 453-462
-
-
Van Wert, A.L.1
Sweet, D.H.2
-
79
-
-
79960666822
-
Deletion of multispecific organic anion transporter Oat1/ Slc22a6 protects against mercury-induced kidney injury
-
Torres AM, Dnyanmote AV, Bush KT, Wu W, Nigam SK. Deletion of multispecific organic anion transporter Oat1/ Slc22a6 protects against mercury-induced kidney injury. J Biol Chem 2011;286 (30):26391-26395.
-
(2011)
J Biol Chem
, vol.286
, Issue.30
, pp. 26391-26395
-
-
Torres, A.M.1
Dnyanmote, A.V.2
Bush, K.T.3
Wu, W.4
Nigam, S.K.5
-
80
-
-
43049121374
-
Multiple organic anion transporters contribute to net renal excretion of uric acid
-
Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics 2008;33 (2):180-192.
-
(2008)
Physiol Genomics
, vol.33
, Issue.2
, pp. 180-192
-
-
Eraly, S.A.1
Vallon, V.2
Rieg, T.3
Gangoiti, J.A.4
Wikoff, W.R.5
Siuzdak, G.6
Barshop, B.A.7
Nigam, S.K.8
-
81
-
-
79958226930
-
Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1)
-
Wikoff WR, Nagle MA, Kouznetsova VL, Tsigelny IF, Nigam SK. Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1). J Proteome Res 2011;10 (6):2842-2851.
-
(2011)
J Proteome Res
, vol.10
, Issue.6
, pp. 2842-2851
-
-
Wikoff, W.R.1
Nagle, M.A.2
Kouznetsova, V.L.3
Tsigelny, I.F.4
Nigam, S.K.5
-
82
-
-
84884698943
-
Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways
-
Wu W, Jamshidi N, Eraly SA, Liu HC, Bush KT, Palsson BO, Nigam SK. Multispecific drug transporter Slc22a8 (Oat3) regulates multiple metabolic and signaling pathways. Drug Metab Dispos 2013;41 (10):1825-1834.
-
(2013)
Drug Metab Dispos
, vol.41
, Issue.10
, pp. 1825-1834
-
-
Wu, W.1
Jamshidi, N.2
Eraly, S.A.3
Liu, H.C.4
Bush, K.T.5
Palsson, B.O.6
Nigam, S.K.7
-
83
-
-
34547196949
-
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members
-
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem 2007;282 (33):23841-23853.
-
(2007)
J Biol Chem
, vol.282
, Issue.33
, pp. 23841-23853
-
-
Kaler, G.1
Truong, D.M.2
Khandelwal, A.3
Nagle, M.4
Eraly, S.A.5
Swaan, P.W.6
Nigam, S.K.7
-
84
-
-
79957453890
-
Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-organic anion transporter1 (Oat1)
-
Kouznetsova VL, Tsigelny IF, Nagle MA, Nigam SK. Elucidation of common pharmacophores from analysis of targeted metabolites transported by the multispecific drug transporter-organic anion transporter1 (Oat1). Bioorg Med Chem 2011;19 (11):3320-3340.
-
(2011)
Bioorg Med Chem
, vol.19
, Issue.11
, pp. 3320-3340
-
-
Kouznetsova, V.L.1
Tsigelny, I.F.2
Nagle, M.A.3
Nigam, S.K.4
-
85
-
-
0026570125
-
Methotrexate and nonsteroidal antiinflammatory drug interactions
-
Frenia ML, Long KS. Methotrexate and nonsteroidal antiinflammatory drug interactions. Ann Pharmacother 1992;26 (2):234-237.
-
(1992)
Ann Pharmacother
, vol.26
, Issue.2
, pp. 234-237
-
-
Frenia, M.L.1
Long, K.S.2
-
86
-
-
84875915261
-
A urate gene-by-diuretic interaction and gout risk in participants with hypertension: results from the ARIC study
-
McAdams-DeMarco MA, Maynard JW, Baer AN, Kao LW, Kottgen A, Coresh J. A urate gene-by-diuretic interaction and gout risk in participants with hypertension: results from the ARIC study. Ann Rheum Dis 2013;72 (5):701-706.
-
(2013)
Ann Rheum Dis
, vol.72
, Issue.5
, pp. 701-706
-
-
McAdams-deMarco, M.A.1
Maynard, J.W.2
Baer, A.N.3
Kao, L.W.4
Kottgen, A.5
Coresh, J.6
-
87
-
-
84860340271
-
Current understanding of drug disposition in kidney disease
-
Naud J, Nolin TD, Leblond FA, Pichette V. Current understanding of drug disposition in kidney disease. J Clin Pharmacol 2012;52 (1 Suppl):10S-22S.
-
(2012)
J Clin Pharmacol
, vol.52
, Issue.1 SUPPL
, pp. 10S-22S
-
-
Naud, J.1
Nolin, T.D.2
Leblond, F.A.3
Pichette, V.4
-
88
-
-
84873933922
-
Expression and function of renal and hepatic organic anion transporters in extrahepatic cholestasis
-
Brandoni A, Hazelhoff MH, Bulacio RP, Torres AM. Expression and function of renal and hepatic organic anion transporters in extrahepatic cholestasis. World J Gastroenterol 2012;18 (44):6387-6397.
-
(2012)
World J Gastroenterol
, vol.18
, Issue.44
, pp. 6387-6397
-
-
Brandoni, A.1
Hazelhoff, M.H.2
Bulacio, R.P.3
Torres, A.M.4
-
90
-
-
84867866650
-
Renal transport of uric acid: evolving concepts and uncertainties
-
Bobulescu IA, Moe OW. Renal transport of uric acid: evolving concepts and uncertainties. Adv Chronic Kidney Dis 2012;19 (6):358-371.
-
(2012)
Adv Chronic Kidney Dis
, vol.19
, Issue.6
, pp. 358-371
-
-
Bobulescu, I.A.1
Moe, O.W.2
-
91
-
-
84873567973
-
The kidney in hyperuricemia and gout
-
Mount DB. The kidney in hyperuricemia and gout. Curr Opin Nephrol Hypertens 2013;22 (2):216-223.
-
(2013)
Curr Opin Nephrol Hypertens
, vol.22
, Issue.2
, pp. 216-223
-
-
Mount, D.B.1
-
92
-
-
84858276787
-
Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies
-
Anzai N, Jutabha P, Amonpatumrat-Takahashi S, Sakurai H. Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies. Clin Exp Nephrol 2012;16 (1):89-95.
-
(2012)
Clin Exp Nephrol
, vol.16
, Issue.1
, pp. 89-95
-
-
Anzai, N.1
Jutabha, P.2
Amonpatumrat-takahashi, S.3
Sakurai, H.4
-
93
-
-
84881614134
-
Reduced renal clearance of cefotaxime in Asians with a low-frequency polymorphism of OAT3 (SLC22A8)
-
Yee SW, Nguyen AN, Brown C, Savic RM, Zhang Y, Castro RA, Cropp CD, Choi JH, Singh D, Tahara H, Stocker SL, Huang Y, Brett CM, Giacomini KM. Reduced renal clearance of cefotaxime in Asians with a low-frequency polymorphism of OAT3 (SLC22A8). J Pharm Sci 2013;102 (9):3451-3457.
-
(2013)
J Pharm Sci
, vol.102
, Issue.9
, pp. 3451-3457
-
-
Yee, S.W.1
Nguyen, A.N.2
Brown, C.3
Savic, R.M.4
Zhang, Y.5
Castro, R.A.6
Cropp, C.D.7
Choi, J.H.8
Singh, D.9
Tahara, H.10
Stocker, S.L.11
Huang, Y.12
Brett, C.M.13
Giacomini, K.M.14
-
94
-
-
29244454212
-
Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis
-
Sakurai Y, Motohashi H, Ogasawara K, Terada T, Masuda S, Katsura T, Mori N, Matsuura M, Doi T, Fukatsu A, Inui K. Pharmacokinetic significance of renal OAT3 (SLC22A8) for anionic drug elimination in patients with mesangial proliferative glomerulonephritis. Pharm Res 2005;22 (12):2016-2022.
-
(2005)
Pharm Res
, vol.22
, Issue.12
, pp. 2016-2022
-
-
Sakurai, Y.1
Motohashi, H.2
Ogasawara, K.3
Terada, T.4
Masuda, S.5
Katsura, T.6
Mori, N.7
Matsuura, M.8
Doi, T.9
Fukatsu, A.10
Inui, K.11
-
95
-
-
84881177123
-
Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin
-
Iacobucci I, Lonetti A, Candoni A, Sazzini M, Papayannidis C, Formica S, Ottaviani E, Ferrari A, Michelutti A, Simeone E, Astolfi A, Abbenante MC, Parisi S, Cattina F, Malagola M, Russo D, Damiani D, Gherlinzoni F, Gottardi M, Baccarani M, Fanin R, Martinelli G. Profiling of drug-metabolizing enzymes/transporters in CD33+ acute myeloid leukemia patients treated with Gemtuzumab-Ozogamicin and Fludarabine, Cytarabine and Idarubicin. Pharmacogenomics J 2013;13 (4):335-341.
-
(2013)
Pharmacogenomics J
, vol.13
, Issue.4
, pp. 335-341
-
-
Iacobucci, I.1
Lonetti, A.2
Candoni, A.3
Sazzini, M.4
Papayannidis, C.5
Formica, S.6
Ottaviani, E.7
Ferrari, A.8
Michelutti, A.9
Simeone, E.10
Astolfi, A.11
Abbenante, M.C.12
Parisi, S.13
Cattina, F.14
Malagola, M.15
Russo, D.16
Damiani, D.17
Gherlinzoni, F.18
Gottardi, M.19
Baccarani, M.20
Fanin, R.21
Martinelli, G.22
more..
-
96
-
-
84872064733
-
Polymorphisms in Genes Encoding Potential Mercury Transporters and Urine Mercury Concentrations in Populations Exposed to Mercury Vapor from Gold Mining
-
Engstrom K, Ameer S, Bernaudat L, Drasch G, Baeuml J, Skerfving S, Bose-O'Reilly S, Broberg K. Polymorphisms in Genes Encoding Potential Mercury Transporters and Urine Mercury Concentrations in Populations Exposed to Mercury Vapor from Gold Mining. Environ Health Perspect 2013;121 (1):85-91.
-
(2013)
Environ Health Perspect
, vol.121
, Issue.1
, pp. 85-91
-
-
Engstrom, K.1
Ameer, S.2
Bernaudat, L.3
Drasch, G.4
Baeuml, J.5
Skerfving, S.6
Bose-o'Reilly, S.7
Broberg, K.8
-
97
-
-
70350223814
-
Blood-brain barrier transporters and response to CNS-active drugs
-
Urquhart BL, Kim RB. Blood-brain barrier transporters and response to CNS-active drugs. Eur J Clin Pharmacol 2009;65 (11):1063-1070.
-
(2009)
Eur J Clin Pharmacol
, vol.65
, Issue.11
, pp. 1063-1070
-
-
Urquhart, B.L.1
Kim, R.B.2
-
98
-
-
59649111761
-
Limited brain distribution of [3R, 4R, 5S]-4-acetamido-5-amino-3- (1-ethylpropoxy)-1-cyclohexene-1-carboxyl ate phosphate (Ro 64-0802), a pharmacologically active form of oseltamivir, by active efflux across the blood-brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4)
-
Ose A, Ito M, Kusuhara H, Yamatsugu K, Kanai M, Shibasaki M, Hosokawa M, Schuetz JD, Sugiyama Y. Limited brain distribution of [3R, 4R, 5S]-4-acetamido-5-amino-3- (1-ethylpropoxy)-1-cyclohexene-1-carboxyl ate phosphate (Ro 64-0802), a pharmacologically active form of oseltamivir, by active efflux across the blood-brain barrier mediated by organic anion transporter 3 (Oat3/Slc22a8) and multidrug resistance-associated protein 4 (Mrp4/Abcc4). Drug Metab Dispos 2009;37 (2):315-321.
-
(2009)
Drug Metab Dispos
, vol.37
, Issue.2
, pp. 315-321
-
-
Ose, A.1
Ito, M.2
Kusuhara, H.3
Yamatsugu, K.4
Kanai, M.5
Shibasaki, M.6
Hosokawa, M.7
Schuetz, J.D.8
Sugiyama, Y.9
-
99
-
-
79954990740
-
Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice
-
Miyajima M, Kusuhara H, Fujishima M, Adachi Y, Sugiyama Y. Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice. Drug Metab Dispos 2011;39 (5):814-819.
-
(2011)
Drug Metab Dispos
, vol.39
, Issue.5
, pp. 814-819
-
-
Miyajima, M.1
Kusuhara, H.2
Fujishima, M.3
Adachi, Y.4
Sugiyama, Y.5
-
100
-
-
3042725709
-
Drug transfer and metabolism by the human placenta
-
Syme MR, Paxton JW, Keelan JA. Drug transfer and metabolism by the human placenta. Clin Pharmacokinet 2004;43 (8):487-514.
-
(2004)
Clin Pharmacokinet
, vol.43
, Issue.8
, pp. 487-514
-
-
Syme, M.R.1
Paxton, J.W.2
Keelan, J.A.3
-
101
-
-
33644841714
-
Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells
-
Zhou F, Illsley NP, You G. Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells. Eur J Pharm Sci 2006;27 (5):518-523.
-
(2006)
Eur J Pharm Sci
, vol.27
, Issue.5
, pp. 518-523
-
-
Zhou, F.1
Illsley, N.P.2
You, G.3
-
102
-
-
33746657602
-
Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20)
-
Schnabolk GW, Youngblood GL, Sweet DH. Transport of estrone sulfate by the novel organic anion transporter Oat6 (Slc22a20). Am J Physiol Renal Physiol 2006;291 (2):F314-F321.
-
(2006)
Am J Physiol Renal Physiol
, vol.291
, Issue.2
, pp. F314-F321
-
-
Schnabolk, G.W.1
Youngblood, G.L.2
Sweet, D.H.3
-
103
-
-
84863054848
-
Effects of tea polyphenols and their polymers on MAPK signaling pathways in cancer research
-
Li W, Mei X, Tu YY. Effects of tea polyphenols and their polymers on MAPK signaling pathways in cancer research. Mini Rev Med Chem 2012;12 (2):120-126.
-
(2012)
Mini Rev Med Chem
, vol.12
, Issue.2
, pp. 120-126
-
-
Li, W.1
Mei, X.2
Tu, Y.Y.3
-
104
-
-
84876436354
-
Xanthurenic acid binds to neuronal G-protein-coupled receptors that secondarily activate cationic channels in the cell line NCB-20
-
Taleb O, Maammar M, Brumaru D, Bourguignon JJ, Schmitt M, Klein C, Kemmel V, Maitre M, Mensah-Nyagan AG. Xanthurenic acid binds to neuronal G-protein-coupled receptors that secondarily activate cationic channels in the cell line NCB-20. PLoS One 2012;7 (11):e48553.
-
(2012)
PLoS One
, vol.7
, Issue.11
, pp. e48553
-
-
Taleb, O.1
Maammar, M.2
Brumaru, D.3
Bourguignon, J.J.4
Schmitt, M.5
Klein, C.6
Kemmel, V.7
Maitre, M.8
Mensah-nyagan, A.G.9
-
105
-
-
84867516785
-
Regulation of human organic anion transporter 4 by parathyroid hormone-related protein and protein kinase A
-
Duan P, Li S, You G. Regulation of human organic anion transporter 4 by parathyroid hormone-related protein and protein kinase A. Int J Biochem Mol Biol 2012;3 (3):322-327.
-
(2012)
Int J Biochem Mol Biol
, vol.3
, Issue.3
, pp. 322-327
-
-
Duan, P.1
Li, S.2
You, G.3
-
106
-
-
84863892043
-
Genetic knockdown of a single organic anion transporter alters the expression of functionally related genes in Malpighian tubules of Drosophila melanogaster
-
Chahine S, Campos A, O'Donnell MJ. Genetic knockdown of a single organic anion transporter alters the expression of functionally related genes in Malpighian tubules of Drosophila melanogaster. J Exp Biol 2012;215(Pt 15):2601-2610.
-
(2012)
J Exp Biol
, vol.215
, Issue.PART 15
, pp. 2601-2610
-
-
Chahine, S.1
Campos, A.2
O'Donnell, M.J.3
-
107
-
-
84868698711
-
Effects of genetic knock-down of organic anion transporter genes on secretion of fluorescent organic ions by Malpighian tubules of Drosophila melanogaster
-
Chahine S, Seabrooke S, O'Donnell MJ. Effects of genetic knock-down of organic anion transporter genes on secretion of fluorescent organic ions by Malpighian tubules of Drosophila melanogaster. Arch Insect Biochem Physiol 2012;81 (4):228-240.
-
(2012)
Arch Insect Biochem Physiol
, vol.81
, Issue.4
, pp. 228-240
-
-
Chahine, S.1
Seabrooke, S.2
O'Donnell, M.J.3
-
108
-
-
84869119273
-
Regulatory pathways for ATP- binding cassette transport proteins in kidney proximal tubules
-
Masereeuw R, Russel FG. Regulatory pathways for ATP- binding cassette transport proteins in kidney proximal tubules. AAPS J. 2012;14 (4):883-894.
-
(2012)
AAPS J
, vol.14
, Issue.4
, pp. 883-894
-
-
Masereeuw, R.1
Russel, F.G.2
-
109
-
-
0036079158
-
The human genome browser at UCSC
-
Kent WJ, Sugnet CW, Furey TS, Roskin KM, Pringle TH, Zahler AM, Haussler D. The human genome browser at UCSC. Genome Res 2002;12 (6):996-1006.
-
(2002)
Genome Res
, vol.12
, Issue.6
, pp. 996-1006
-
-
Kent, W.J.1
Sugnet, C.W.2
Furey, T.S.3
Roskin, K.M.4
Pringle, T.H.5
Zahler, A.M.6
Haussler, D.7
-
110
-
-
79958171563
-
The GUDMAP database-an online resource for genitourinary research
-
Harding SD, Armit C, Armstrong J, Brennan J, Cheng Y, Haggarty B, Houghton D, Lloyd-Mac Gilp S, Pi X, Roochun Y, Sharghi M, Tindal C, McMahon AP, Gottesman B, Little MH, Georgas K, Aronow BJ, Potter SS, Brunskill EW, Southard-Smith EM, Mendelsohn C, Baldock RA, Davies JA, Davidson D. The GUDMAP database-an online resource for genitourinary research. Development 2011;138 (13):2845-2853.
-
(2011)
Development
, vol.138
, Issue.13
, pp. 2845-2853
-
-
Harding, S.D.1
Armit, C.2
Armstrong, J.3
Brennan, J.4
Cheng, Y.5
Haggarty, B.6
Houghton, D.7
Lloyd-mac Gilp, S.8
Pi, X.9
Roochun, Y.10
Sharghi, M.11
Tindal, C.12
McMahon, A.P.13
Gottesman, B.14
Little, M.H.15
Georgas, K.16
Aronow, B.J.17
Potter, S.S.18
Brunskill, E.W.19
Southard-smith, E.M.20
Mendelsohn, C.21
Baldock, R.A.22
Davies, J.A.23
Davidson, D.24
more..
|