Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1)

Journal of Proteome Research

Volumn 10, Issue 6, 2011, Pages 2842-2851

  Wikoff, William R ^a   Nagle, Megha A ^b   Kouznetsova, Valentina L ^c   Tsigelny, Igor F ^d,e   Nigam, Sanjay K ^b,c,d,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Pediatrics ^*  (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

flexible alignment; mass spectrometry; metabolic profiling; pharmacophore modeling; self consistent field (SCF) energy

Indexed keywords

INDICAN; KYNURENINE; NUCLEOSIDE; ORGANIC ANION TRANSPORTER 1; PANTOTHENIC ACID; PYRIDOXIC ACID; TRYPTOPHAN; UREMIC TOXIN; XANTHURENIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BINDING ASSAY; BIOME; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE DELETION; HYDROPHILICITY; IN VITRO STUDY; METABOLISM; METABOLOMICS; MOUSE; NONHUMAN; OOCYTE; PHARMACOPHORE; PRIORITY JOURNAL; URINARY EXCRETION; XENOPUS;

ANIMALS; CELL MEMBRANE PERMEABILITY; FLUORESCENT DYES; INDICAN; KYNURENINE; METABOLOME; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; OOCYTES; ORGANIC ANION TRANSPORT PROTEIN 1; PANTOTHENIC ACID; PYRIDOXIC ACID; SULFURIC ACID ESTERS; UREMIA; URINALYSIS; XANTHURENATES; XENOPUS;

AVENA; MUS;

EID: 79958226930     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200093w     Document Type: Article

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