-
1
-
-
0030784438
-
An artificial intelligence approach to motif discovery in protein sequences: Application to steriod dehydrogenases
-
Bailey TL, Baker ME, Elkan CP. An artificial intelligence approach to motif discovery in protein sequences: application to steriod dehydrogenases. J Steroid Biochem Mol Biol 62: 29-44, 1997.
-
(1997)
J Steroid Biochem Mol Biol
, vol.62
, pp. 29-44
-
-
Bailey, T.L.1
Baker, M.E.2
Elkan, C.P.3
-
2
-
-
2442700344
-
Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels
-
Buist SC, Klaassen CD. Rat and mouse differences in gender-predominant expression of organic anion transporter (Oat1-3; Slc22a6-8) mRNA levels. Drug Metab Dispos 32: 620-625, 2004.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 620-625
-
-
Buist, S.C.1
Klaassen, C.D.2
-
3
-
-
0038728565
-
Transport of organic anions across the basolateral membrane of proximal tubule cells
-
Burckhardt BC, Burckhardt G. Transport of organic anions across the basolateral membrane of proximal tubule cells. Rev Physiol Biochem Pharmacol 146: 95-158, 2003.
-
(2003)
Rev Physiol Biochem Pharmacol
, vol.146
, pp. 95-158
-
-
Burckhardt, B.C.1
Burckhardt, G.2
-
4
-
-
0037161834
-
Molecular identification of a renal urate anion exchanger that regulates blood urate levels
-
Enomoto A, Kimura H, Chairoungdua A, Shigeta Y, Jutabha P, Cha SH, Hosoyamada M, Takeda M, Sekine T, Igarashi T, Matsuo H, Kikuchi Y, Oda T, Ichida K, Hosoya T, Shimokata K, Niwa T, Kanai Y, Endou H. Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 417: 447-452, 2002.
-
(2002)
Nature
, vol.417
, pp. 447-452
-
-
Enomoto, A.1
Kimura, H.2
Chairoungdua, A.3
Shigeta, Y.4
Jutabha, P.5
Cha, S.H.6
Hosoyamada, M.7
Takeda, M.8
Sekine, T.9
Igarashi, T.10
Matsuo, H.11
Kikuchi, Y.12
Oda, T.13
Ichida, K.14
Hosoya, T.15
Shimokata, K.16
Niwa, T.17
Kanai, Y.18
Endou, H.19
-
5
-
-
0037427506
-
Organic anion and cation transporters occur in pairs of similar and similarly expressed genes
-
Eraly SA, Hamilton BA, Nigam SK. Organic anion and cation transporters occur in pairs of similar and similarly expressed genes. Biochem Biophys Res Commun 300: 333-342, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.300
, pp. 333-342
-
-
Eraly, S.A.1
Hamilton, B.A.2
Nigam, S.K.3
-
6
-
-
3042630508
-
Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters
-
Eraly SA, Monte JC, Nigam SK. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Physiol Genomics 18: 12-24, 2004.
-
(2004)
Physiol Genomics
, vol.18
, pp. 12-24
-
-
Eraly, S.A.1
Monte, J.C.2
Nigam, S.K.3
-
7
-
-
0036401507
-
Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters
-
Eraly SA, Nigam SK. Novel human cDNAs homologous to Drosophila Orct and mammalian carnitine transporters. Biochem Biophys Res Commun 297: 1159-1166, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 1159-1166
-
-
Eraly, S.A.1
Nigam, S.K.2
-
8
-
-
43049121374
-
Multiple organic anion transporters contribute to net renal excretion of uric acid
-
Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics 33: 180-192, 2008.
-
(2008)
Physiol Genomics
, vol.33
, pp. 180-192
-
-
Eraly, S.A.1
Vallon, V.2
Rieg, T.3
Gangoiti, J.A.4
Wikoff, W.R.5
Siuzdak, G.6
Barshop, B.A.7
Nigam, S.K.8
-
9
-
-
33646165531
-
Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice
-
Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem 281: 5072-5083, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 5072-5083
-
-
Eraly, S.A.1
Vallon, V.2
Vaughn, D.A.3
Gangoiti, J.A.4
Richter, K.5
Nagle, M.6
Monte, J.C.7
Rieg, T.8
Truong, D.M.9
Long, J.M.10
Barshop, B.A.11
Kaler, G.12
Nigam, S.K.13
-
10
-
-
0028063302
-
Drug excretion mediated by a new prototype of polyspecific transporter
-
Grundemann D, Gorboulev V, Gambaryan S, Veyhl M, Koepsell H. Drug excretion mediated by a new prototype of polyspecific transporter. Nature 372: 549-552, 1994.
-
(1994)
Nature
, vol.372
, pp. 549-552
-
-
Grundemann, D.1
Gorboulev, V.2
Gambaryan, S.3
Veyhl, M.4
Koepsell, H.5
-
11
-
-
17144434313
-
Hidden Markov model analysis of motifs in steroid dehydrogenases and their homologs
-
Grundy WN, Bailey TL, Elkan CP, Baker ME. Hidden Markov model analysis of motifs in steroid dehydrogenases and their homologs. Biochem Biophys Res Commun 231: 760-766, 1997.
-
(1997)
Biochem Biophys Res Commun
, vol.231
, pp. 760-766
-
-
Grundy, W.N.1
Bailey, T.L.2
Elkan, C.P.3
Baker, M.E.4
-
12
-
-
35548966750
-
Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family
-
Jacobsson JA, Haitina T, Lindblom J, Fredriksson R. Identification of six putative human transporters with structural similarity to the drug transporter SLC22 family. Genomics, 2007.
-
(2007)
Genomics
-
-
Jacobsson, J.A.1
Haitina, T.2
Lindblom, J.3
Fredriksson, R.4
-
13
-
-
34547196949
-
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members
-
Kaler G, Truong DM, Khandelwal A, Nagle M, Eraly SA, Swaan PW, Nigam SK. Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem 282: 23841-23853, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 23841-23853
-
-
Kaler, G.1
Truong, D.M.2
Khandelwal, A.3
Nagle, M.4
Eraly, S.A.5
Swaan, P.W.6
Nigam, S.K.7
-
14
-
-
0030940999
-
Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney
-
Lopez-Nieto CE, You G, Bush KT, Barros EJ, Beier DR, Nigam SK. Molecular cloning and characterization of NKT, a gene product related to the organic cation transporter family that is almost exclusively expressed in the kidney. J Biol Chem 272: 6471-6478, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 6471-6478
-
-
Lopez-Nieto, C.E.1
You, G.2
Bush, K.T.3
Barros, E.J.4
Beier, D.R.5
Nigam, S.K.6
-
15
-
-
0034004157
-
Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct
-
Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK. Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol 278: F635-F643, 2000.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Pavlova, A.1
Sakurai, H.2
Leclercq, B.3
Beier, D.R.4
Yu, A.S.5
Nigam, S.K.6
-
16
-
-
33846010171
-
A three-dimensional model of human organic anion transporter 1: Aromatic amino acids required for substrate transport
-
Perry JL, Dembla-Rajpal N, Hall LA, Pritchard JB. A three-dimensional model of human organic anion transporter 1: aromatic amino acids required for substrate transport. J Biol Chem 281: 38071-38079, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 38071-38079
-
-
Perry, J.L.1
Dembla-Rajpal, N.2
Hall, L.A.3
Pritchard, J.B.4
-
17
-
-
17644411713
-
Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease
-
Popp C, Gorboulev V, Muller TD, Gorbunov D, Shatskaya N, Koepsell H. Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease. Mol Pharmacol 67: 1600-1611, 2005.
-
(2005)
Mol Pharmacol
, vol.67
, pp. 1600-1611
-
-
Popp, C.1
Gorboulev, V.2
Muller, T.D.3
Gorbunov, D.4
Shatskaya, N.5
Koepsell, H.6
-
18
-
-
33751329250
-
-
Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature 444: 444-454, 2006.
-
Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature 444: 444-454, 2006.
-
-
-
-
19
-
-
12344321851
-
Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: Insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecules
-
Salas-Burgos A, Iserovich P, Zuniga F, Vera JC, Fischbarg J. Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecules. Biophys J 87: 2990-2999, 2004.
-
(2004)
Biophys J
, vol.87
, pp. 2990-2999
-
-
Salas-Burgos, A.1
Iserovich, P.2
Zuniga, F.3
Vera, J.C.4
Fischbarg, J.5
-
20
-
-
34247400616
-
Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate
-
Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y. Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate. Hepatology 45: 1046-1055, 2007.
-
(2007)
Hepatology
, vol.45
, pp. 1046-1055
-
-
Shin, H.J.1
Anzai, N.2
Enomoto, A.3
He, X.4
Kim do, K.5
Endou, H.6
Kanai, Y.7
-
21
-
-
0034817065
-
Isolation of a family of organic anion transporters from human liver and kidney
-
Sun W, Wu RR, van Poelje PD, Erion MD. Isolation of a family of organic anion transporters from human liver and kidney. Biochem Biophys Res Commun 283: 417-422, 2001.
-
(2001)
Biochem Biophys Res Commun
, vol.283
, pp. 417-422
-
-
Sun, W.1
Wu, R.R.2
van Poelje, P.D.3
Erion, M.D.4
-
22
-
-
0037376163
-
Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient
-
Sweet DH, Chan LM, Walden R, Yang XP, Miller DS, Pritchard JB. Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient. Am J Physiol Renal Physiol 284: F763-F769, 2003.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Sweet, D.H.1
Chan, L.M.2
Walden, R.3
Yang, X.P.4
Miller, D.S.5
Pritchard, J.B.6
-
23
-
-
33644499212
-
Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models
-
Sweet DH, Eraly SA, Vaughn DA, Bush KT, Nigam SK. Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney Int 69: 837-845, 2006.
-
(2006)
Kidney Int
, vol.69
, pp. 837-845
-
-
Sweet, D.H.1
Eraly, S.A.2
Vaughn, D.A.3
Bush, K.T.4
Nigam, S.K.5
-
24
-
-
0037178852
-
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 [Oat3 (Slc22a8)] knockout mice
-
Sweet DH, Miller DS, Pritchard JB, Fujiwara Y, Beier DR, Nigam SK. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 [Oat3 (Slc22a8)] knockout mice. J Biol Chem 277: 26934-26943, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 26934-26943
-
-
Sweet, D.H.1
Miller, D.S.2
Pritchard, J.B.3
Fujiwara, Y.4
Beier, D.R.5
Nigam, S.K.6
-
25
-
-
0032997735
-
Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency
-
Tang NL, Ganapathy V, Wu X, Hui J, Seth P, Yuen PM, Wanders RJ, Fok TF, Hjelm NM. Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency. Hum Mol Genet 8: 655-660, 1999.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 655-660
-
-
Tang, N.L.1
Ganapathy, V.2
Wu, X.3
Hui, J.4
Seth, P.5
Yuen, P.M.6
Wanders, R.J.7
Fok, T.F.8
Hjelm, N.M.9
-
26
-
-
43749115381
-
Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination
-
Truong DM, Kaler G, Khandelwal A, Swaan PW, Nigam SK. Multi-level analysis of organic anion transporters 1, 3, and 6 reveals major differences in structural determinants of antiviral discrimination. J Biol Chem 283: 8654-8663, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 8654-8663
-
-
Truong, D.M.1
Kaler, G.2
Khandelwal, A.3
Swaan, P.W.4
Nigam, S.K.5
-
27
-
-
0033515017
-
Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency
-
Wang Y, Ye J, Ganapathy V, Longo N. Mutations in the organic cation/carnitine transporter OCTN2 in primary carnitine deficiency. Proc Natl Acad Sci USA 96: 2356-2360, 1999.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2356-2360
-
-
Wang, Y.1
Ye, J.2
Ganapathy, V.3
Longo, N.4
-
28
-
-
3242707822
-
Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney
-
Youngblood GL, Sweet DH. Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney. Am J Physiol Renal Physiol 287: F236-F244, 2004.
-
(2004)
Am J Physiol Renal Physiol
, vol.287
-
-
Youngblood, G.L.1
Sweet, D.H.2
-
29
-
-
27144555426
-
A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2)
-
Zhang X, Shirahatti NV, Mahadevan D, Wright SH. A conserved glutamate residue in transmembrane helix 10 influences substrate specificity of rabbit OCT2 (SLC22A2). J Biol Chem 280: 34813-34822, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 34813-34822
-
-
Zhang, X.1
Shirahatti, N.V.2
Mahadevan, D.3
Wright, S.H.4
|