Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats

Drug Metabolism and Disposition

Volumn 39, Issue 8, 2011, Pages 1363-1369

  Naud, Judith ^a   Michaud, Josée ^a   Beauchemin, Stéphanie ^a   Hébert, Marie Josée ^b   Roger, Michel ^a,b   Lefrancois, Stéphane ^a   Leblond, Francois A ^a   Pichette, Vincent ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; CYTOCHROME P450; CYTOCHROME P450 1A; CYTOCHROME P450 3A; DIGOXIN; GLYCOPROTEIN P; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTER K1; ORGANIC ANION TRANSPORTER K2; ORGANIC ANION TRANSPORTER POLYPEPTIDE 1; ORGANIC ANION TRANSPORTER POLYPEPTIDE 2; ORGANIC ANION TRANSPORTER POLYPEPTIDE 3; ORGANIC ANION TRANSPORTER POLYPEPTIDE 4C1; PENICILLIN G; SODIUM PHOSPHATE COTRANSPORTER 1; UNCLASSIFIED DRUG; URATE TRANSPORTER 1; URATE TRANSPORTER 2; UREA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DRUG ACCUMULATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KIDNEY BIOPSY; KIDNEY CLEARANCE; KIDNEY PROXIMAL TUBULE; MALE; NEPHRECTOMY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOACTIVITY; RAT; REAL TIME POLYMERASE CHAIN REACTION; UREA BLOOD LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELL LINE; CULTURE MEDIA; CYTOCHROME P-450 ENZYME SYSTEM; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HUMANS; KIDNEY; KIDNEY FAILURE, CHRONIC; KIDNEY FUNCTION TESTS; KIDNEY TUBULES, PROXIMAL; MALE; MEMBRANE TRANSPORT PROTEINS; PHARMACEUTICAL PREPARATIONS; RATS; RATS, SPRAGUE-DAWLEY; RHODAMINE 123; RNA, MESSENGER; UREMIA;

RATTUS;

EID: 79960615869     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.039115     Document Type: Article

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