-
1
-
-
84862852341
-
-
Accessed July 28
-
World Health Organization and Alzheimer's Disease International. Dementia: a public health priority 2012. http://www. who. int/mental_health/publications/dementia_report_2 012/en/. Accessed July 28, 2013.
-
(2013)
Dementia: A public health priority 2012
-
-
-
5
-
-
84866290209
-
Dementia: A global health priority-highlights from an ADI and World Health Organization report
-
Wortmann M. Dementia: a global health priority-highlights from an ADI and World Health Organization report. Alzheimers Res Ther 2012; 4: 40.
-
(2012)
Alzheimers Res Ther
, vol.4
, pp. 40
-
-
Wortmann, M.1
-
6
-
-
84867716731
-
Making Alzheimer's and dementia research fit for populations
-
Brayne C, Davis D. Making Alzheimer's and dementia research fit for populations. Lancet 2012; 380: 1441-3.
-
(2012)
Lancet
, vol.380
, pp. 1441-1443
-
-
Brayne, C.1
Davis, D.2
-
7
-
-
84871645397
-
Clinical diagnosis in preclinical stage of Alzheimer's disease
-
Fuentes P. Clinical diagnosis in preclinical stage of Alzheimer's disease. Arch Med Res 2012; 43: 667-70.
-
(2012)
Arch Med Res
, vol.43
, pp. 667-670
-
-
Fuentes, P.1
-
8
-
-
84871652602
-
Emerging noninvasive biomarkers for early detection of Alzheimer's disease
-
Guzmán-Martínez L, Farías GA, Maccioni RB. Emerging noninvasive biomarkers for early detection of Alzheimer's disease. Arch Med Res 2012; 43: 663-6.
-
(2012)
Arch Med Res
, vol.43
, pp. 663-666
-
-
Guzmán-Martínez, L.1
Farías, G.A.2
Maccioni, R.B.3
-
9
-
-
77249153190
-
Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease
-
Hernandez CM, Kayed R, Zheng H, Sweatt JD, Dineley KT. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. J Neurosci 2010; 30: 2442-53.
-
(2010)
J Neurosci
, vol.30
, pp. 2442-2453
-
-
Hernandez, C.M.1
Kayed, R.2
Zheng, H.3
Sweatt, J.D.4
Dineley, K.T.5
-
10
-
-
84872441075
-
Modulation of +7 nicotinic acetylcholine receptor and fibrillar amyloid-κ interactions in Alzheimer's disease brain
-
Ni R, Marutle A, Nordberg A. Modulation of +7 nicotinic acetylcholine receptor and fibrillar amyloid-κ interactions in Alzheimer's disease brain. J Alzheimers Dis 2013; 33: 841-51.
-
(2013)
J Alzheimers Dis
, vol.33
, pp. 841-851
-
-
Ni, R.1
Marutle, A.2
Nordberg, A.3
-
11
-
-
84879732252
-
A induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss
-
Jun 17. [Epub ahead of print]
-
Talantova M, Sanz-Blasco S, Zhang X, et al. A induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss. Proc Natl Acad Sci USA 2013 Jun 17. [Epub ahead of print].
-
(2013)
Proc Natl Acad Sci USA
-
-
Talantova, M.1
Sanz-Blasco, S.2
Zhang, X.3
-
12
-
-
84882778234
-
On the Interaction of κ-Amyloid Peptides and +7-Nicotinic Acetylcholine Receptors in Alzheimer's Disease
-
Apr 29. [Epub ahead of print]
-
Oz M, Lorke DE, K-Heung S, Petroianu G. On the Interaction of κ-Amyloid Peptides and +7-Nicotinic Acetylcholine Receptors in Alzheimer's Disease. Curr Alzheimer Res 2013 Apr 29. [Epub ahead of print].
-
(2013)
Curr Alzheimer Res
-
-
Oz, M.1
Lorke, D.E.2
Heung, K.S.3
Petroianu, G.4
-
13
-
-
84860468079
-
+7 nicotinic acetylcholine receptors in Alzheimer's disease: Neuroprotective, neurotrophic or both?
-
Hernandez CM, Dineley KT. +7 nicotinic acetylcholine receptors in Alzheimer's disease: neuroprotective, neurotrophic or both? Curr Drug Targets 2012; 13: 613-22.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 613-622
-
-
Hernandez, C.M.1
Dineley, K.T.2
-
14
-
-
80052033738
-
Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease
-
Parri HR, Hernandez CM, Dineley KT. Research update: Alpha7 nicotinic acetylcholine receptor mechanisms in Alzheimer's disease. Biochem Pharmacol 2011; 82: 931-42.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 931-942
-
-
Parri, H.R.1
Hernandez, C.M.2
Dineley, K.T.3
-
15
-
-
0033983966
-
Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease
-
Guan ZZ, Zhang X, Ravid R, Nordberg A. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. J Neurochem 2000; 74: 237-43.
-
(2000)
J Neurochem
, vol.74
, pp. 237-243
-
-
Guan, Z.Z.1
Zhang, X.2
Ravid, R.3
Nordberg, A.4
-
16
-
-
37149055806
-
Alpha7 nicotinic receptor upregulation in cholinergic basal forebrain neurons in Alzheimer disease
-
Counts SE, He B, Che S, et al. Alpha7 nicotinic receptor upregulation in cholinergic basal forebrain neurons in Alzheimer disease. Arch Neurol 2007; 64: 1771-6.
-
(2007)
Arch Neurol
, vol.64
, pp. 1771-1776
-
-
Counts, S.E.1
He, B.2
Che, S.3
-
17
-
-
13444280311
-
High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: A possible association with neuritic plaques
-
Yu WF, Guan ZZ, Bogdanovic N, Nordberg A. High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques. Exp Neurol 2005; 192: 215-25.
-
(2005)
Exp Neurol
, vol.192
, pp. 215-225
-
-
Yu, W.F.1
Guan, Z.Z.2
Bogdanovic, N.3
Nordberg, A.4
-
18
-
-
0019972810
-
The cholinergic hypothesis of geriatric memory dysfunction
-
Bartus RT, Dean RL 3rd, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction. Science. 1982; 217: 408-14.
-
(1982)
Science
, vol.217
, pp. 408-414
-
-
Bartus, R.T.1
Dean, R.L.2
Beer, B.3
Lippa, A.S.4
-
19
-
-
0034125843
-
On neurodegenerative diseases, models, and treatment strategies: Lessons learned and lessons forgotten a generation following the cholinergic hypothesis
-
Bartus RT. On neurodegenerative diseases, models, and treatment strategies: lessons learned and lessons forgotten a generation following the cholinergic hypothesis. Exp Neurol 2000; 163: 495-529.
-
(2000)
Exp Neurol
, vol.163
, pp. 495-529
-
-
Bartus, R.T.1
-
21
-
-
33646035489
-
International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment
-
Gauthier S, Reisberg B, Zaudig M, et al. International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment. Lancet 2006; 367: 1262-70.
-
(2006)
Lancet
, vol.367
, pp. 1262-1270
-
-
Gauthier, S.1
Reisberg, B.2
Zaudig, M.3
-
22
-
-
84858342780
-
Cholinergic system function and cognition in mild cognitive impairment
-
Haense C, Kalbe E, Herholz K, et al. Cholinergic system function and cognition in mild cognitive impairment. Neurobiol Aging 2012; 33: 867-77.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 867-877
-
-
Haense, C.1
Kalbe, E.2
Herholz, K.3
-
23
-
-
41149114057
-
Acetylcholine esterase activity in mild cognitive impairment and Alzheimer's disease
-
Herholz K. Acetylcholine esterase activity in mild cognitive impairment and Alzheimer's disease. Eur J Nucl Med Mol Imaging 2008; 35 Suppl 1: S25-9.
-
(2008)
Eur J Nucl Med Mol Imaging
, vol.35
, pp. 25-29
-
-
Herholz, K.1
-
24
-
-
30344460006
-
Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation-a pharmacological fMRI study
-
Goekoop R, Scheltens P, Barkhoh F, Rombouts SARB. Cholinergic challenge in Alzheimer patients and mild cognitive impairment differentially affects hippocampal activation-a pharmacological fMRI study. Brain 2006; 129: 141-57.
-
(2006)
Brain
, vol.129
, pp. 141-157
-
-
Goekoop, R.1
Scheltens, P.2
Barkhoh, F.3
Rombouts, S.A.R.B.4
-
25
-
-
79955727727
-
The cholinergic system in aging and neuronal degeneration
-
Schliebs R, Arendt T. The cholinergic system in aging and neuronal degeneration. Behav Brain Res 2011; 221: 555-63.
-
(2011)
Behav Brain Res
, vol.221
, pp. 555-563
-
-
Schliebs, R.1
Arendt, T.2
-
27
-
-
84861078831
-
A review: Inflammatory process in Alzheimer's disease, role of cytokines
-
Rubio-Perez JM, Morillas-Ruiz JM. A review: inflammatory process in Alzheimer's disease, role of cytokines. Scientific World J 2012; 2012: 756357.
-
(2012)
Scientific World J
, vol.2012
-
-
Rubio-Perez, J.M.1
Morillas-Ruiz, J.M.2
-
28
-
-
84872699164
-
Review: Systemic inflammation and Alzheimer's disease
-
Holmes C. Review: systemic inflammation and Alzheimer's disease. Neuropathol Appl Neurobiol 2013; 39: 51-68.
-
(2013)
Neuropathol Appl Neurobiol
, vol.39
, pp. 51-68
-
-
Holmes, C.1
-
29
-
-
79954486783
-
Does a pro-inflammatory process precede Alzheimer's disease and mild cognitive impairment?
-
Ferretti MT, Cuello AC. Does a pro-inflammatory process precede Alzheimer's disease and mild cognitive impairment? Curr Alzheimer Res 2011; 8: 164-74.
-
(2011)
Curr Alzheimer Res
, vol.8
, pp. 164-174
-
-
Ferretti, M.T.1
Cuello, A.C.2
-
30
-
-
70349816648
-
The neurology of the immune system: Neural reflexes regulate immunity
-
Rosas-Ballina M, Tracey KJ. The neurology of the immune system: neural reflexes regulate immunity. Neuron 2009; 64: 28-32.
-
(2009)
Neuron
, vol.64
, pp. 28-32
-
-
Rosas-Ballina, M.1
Tracey, K.J.2
-
31
-
-
84925882635
-
-
(Accessed July 28, 2013)
-
http://www. alzheimersepidemic. com/Drug2013. pdf. (Accessed July 28, 2013).
-
-
-
-
32
-
-
42749100518
-
Cholinesterase inhibitors for Alzheimer's disease
-
Birks J. Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst Rev 2006; 1: CD005593.
-
(2006)
Cochrane Database Syst Rev
, vol.1
-
-
Birks, J.1
-
33
-
-
84872460554
-
Cholinesterase inhibitors for mild cognitive impairment
-
Russ TC, Morling JR. Cholinesterase inhibitors for mild cognitive impairment. Cochrane Database Syst Rev 2012; 9: CD009132.
-
(2012)
Cochrane Database Syst Rev
, vol.9
-
-
Russ, T.C.1
Morling, J.R.2
-
34
-
-
84874393127
-
ACP Journal Club. Review: Cholinesterase inhibitors do not reduce progression to dementia from mild cognitive impairment
-
Masoodi N. ACP Journal Club. Review: cholinesterase inhibitors do not reduce progression to dementia from mild cognitive impairment. Ann Intern Med 2013; 158: JC3.
-
(2013)
Ann Intern Med
, vol.158
-
-
Masoodi, N.1
-
35
-
-
84876227085
-
Little evidence that cholinesterase inhibitors prevent progression of mild cognitive impairment to dementia, but they are associated with adverse effects
-
Rojas-Fernandez CH. Little evidence that cholinesterase inhibitors prevent progression of mild cognitive impairment to dementia, but they are associated with adverse effects. Evid Based Ment Health 2013; 16: 39.
-
(2013)
Evid Based Ment Health
, vol.16
, pp. 39
-
-
Rojas-Fernandez, C.H.1
-
36
-
-
84877966990
-
From traditional European medicine to discovery of new drug candidates for the treatment of dementia and Alzheimer's disease: Acetylcholinesterase inhibitors
-
Russo P, Frustaci A, Del Bufalo A, Fini M, Cesario A. From traditional European medicine to discovery of new drug candidates for the treatment of dementia and Alzheimer's disease: acetylcholinesterase inhibitors. Curr Med Chem 2013; 20: 976-83.
-
(2013)
Curr Med Chem
, vol.20
, pp. 976-983
-
-
Russo, P.1
Frustaci, A.2
Del Bufalo, A.3
Fini, M.4
Cesario, A.5
-
37
-
-
34548358824
-
Nicotinic control of axon excitability regulates thalamocortical transmission
-
Kawai H, Lazar R, Metherate R. Nicotinic control of axon excitability regulates thalamocortical transmission. Nat. Neurosci 2007; 10: 1168-75.
-
(2007)
Nat Neurosci
, vol.10
, pp. 1168-1175
-
-
Kawai, H.1
Lazar, R.2
Metherate, R.3
-
38
-
-
2542455574
-
Frequency-dependent modulation of dopamine release by nicotine
-
Zhang H, Sulzer D. Frequency-dependent modulation of dopamine release by nicotine. Nat. Neurosci 2004; 7: 581-2.
-
(2004)
Nat Neurosci
, vol.7
, pp. 581-582
-
-
Zhang, H.1
Sulzer, D.2
-
39
-
-
34548694967
-
Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors
-
McKay BE, Placzek AN, Dani JA. Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors. Biochem Pharmacol 2007; 74: 1120-33.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1120-1133
-
-
McKay, B.E.1
Placzek, A.N.2
Dani, J.A.3
-
40
-
-
58049181014
-
Nicotine-induced plasticity during development: Modulation of the cholinergic system and long-term consequences for circuits involved in attention and sensory processing
-
Heath CJ, Picciotto MR. Nicotine-induced plasticity during development: modulation of the cholinergic system and long-term consequences for circuits involved in attention and sensory processing. Neuropharmacol 2009; 56 Suppl 1: 254-62.
-
(2009)
Neuropharmacol
, vol.56
, pp. 254-262
-
-
Heath, C.J.1
Picciotto, M.R.2
-
41
-
-
72449129007
-
Alpha7 neuronal nicotinic receptors: The missing link to understanding Alzheimer's etiopathology?
-
Bencherif M, Lippiello PM. Alpha7 neuronal nicotinic receptors: the missing link to understanding Alzheimer's etiopathology? Med Hypotheses 2010; 74: 281-5.
-
(2010)
Med Hypotheses
, vol.74
, pp. 281-285
-
-
Bencherif, M.1
Lippiello, P.M.2
-
42
-
-
84870042685
-
The nicotinic acetylcholine receptor: The founding father of the pentameric ligand-gated ion channel superfamily
-
Changeux JP. The nicotinic acetylcholine receptor: the founding father of the pentameric ligand-gated ion channel superfamily. J Biol Chem 2012; 287: 40207-15.
-
(2012)
J Biol Chem
, vol.287
, pp. 40207-40215
-
-
Changeux, J.P.1
-
43
-
-
84861963413
-
Structure and pharmacology of pentameric receptor channels: From bacteria to brain
-
Corringer PJ, Poitevin F, Prevost MS, et al. Structure and pharmacology of pentameric receptor channels: from bacteria to brain. Structure 2012; 20: 941-56.
-
(2012)
Structure
, vol.20
, pp. 941-956
-
-
Corringer, P.J.1
Poitevin, F.2
Prevost, M.S.3
-
44
-
-
84859914196
-
α7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: The search for a Ca(2+) optimum
-
Uteshev VV. α7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimum. Adv Exp Med Biol 2012; 740: 603-38.
-
(2012)
Adv Exp Med Biol
, vol.740
, pp. 603-638
-
-
Uteshev, V.V.1
-
45
-
-
67549109441
-
Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system
-
Shen JX, Yakel JL. Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system. Acta Pharmacol Sin 2009 30: 673-80.
-
(2009)
Acta Pharmacol Sin
, vol.30
, pp. 673-680
-
-
Shen, J.X.1
Yakel, J.L.2
-
46
-
-
0032535583
-
Mammalian nicotinic receptors with alpha7 subunits that slowly desensitize and rapidly recover from alphabungarotoxin blockade
-
Cuevas J, Berg DK. Mammalian nicotinic receptors with alpha7 subunits that slowly desensitize and rapidly recover from alphabungarotoxin blockade. J Neurosci. 1998; 18: 10335-44.
-
(1998)
J Neurosci
, vol.18
, pp. 10335-10344
-
-
Cuevas, J.1
Berg, D.K.2
-
47
-
-
0026482631
-
Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium
-
Franklin JL, Johnson EM Jr. Suppression of programmed neuronal death by sustained elevation of cytoplasmic calcium. Trends Neurosci. 1992; 15: 501-8.
-
(1992)
Trends Neurosci
, vol.15
, pp. 501-508
-
-
Franklin, J.L.1
Johnson, E.M.2
-
48
-
-
0025605864
-
A neuronal nicotinic acetylcholinereceptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX
-
Couturier S, Bertrand D, Matter JM, et al. A neuronal nicotinic acetylcholinereceptor subunit (alpha 7) is developmentally regulated and forms a homo-oligomeric channel blocked by alpha-BTX. Neuron 1990; 5: 847-56.
-
(1990)
Neuron
, vol.5
, pp. 847-856
-
-
Couturier, S.1
Bertrand, D.2
Matter, J.M.3
-
49
-
-
84860444144
-
α7-Nicotinic acetylcholine receptors: An old actor for new different roles
-
Russo P, Taly A. α7-Nicotinic acetylcholine receptors: an old actor for new different roles. Curr Drug Targets 2012; 13: 574-8.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 574-578
-
-
Russo, P.1
Taly, A.2
-
50
-
-
0037032103
-
Activation and inhibition of native neuronal alphabungarotoxin-sensitive nicotinic ACh receptors
-
Uteshev VV, Meyer EM, Papke RL. Activation and inhibition of native neuronal alphabungarotoxin-sensitive nicotinic ACh receptors. Brain Research 2002; 948: 33-46.
-
(2002)
Brain Research
, vol.948
, pp. 33-46
-
-
Uteshev, V.V.1
Meyer, E.M.2
Papke, R.L.3
-
51
-
-
78651189765
-
On the nature of allosteric transitions: A plausible model
-
Monod J, Wyman J, Changeux JP. On the nature of allosteric transitions: A plausible model. J Mol Biol. 1965; 12: 88-118.
-
(1965)
J Mol Biol
, vol.12
, pp. 88-118
-
-
Monod, J.1
Wyman, J.2
Changeux, J.P.3
-
52
-
-
69949159308
-
Nicotinic receptors: Allosteric transitions and therapeutic targets in the nervous system
-
Taly A, Corringer PJ, Guedin D, Lestage P, Changeux JP. Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system. Nat Rev Drug Discov 2009; 8: 733-50.
-
(2009)
Nat Rev Drug Discov
, vol.8
, pp. 733-750
-
-
Taly, A.1
Corringer, P.J.2
Guedin, D.3
Lestage, P.4
Changeux, J.P.5
-
53
-
-
84861219631
-
Allostery and the Monod-Wyman-Changeux model after 50 years
-
Changeux JP. Allostery and the Monod-Wyman-Changeux model after 50 years. Annu Rev Biophys 2012; 41: 103-33.
-
(2012)
Annu Rev Biophys
, vol.41
, pp. 103-133
-
-
Changeux, J.P.1
-
54
-
-
84884568392
-
The concept of allosteric interaction and its consequences for the chemistry of the brain
-
Jul 22. [Epub ahead of print]
-
Changeux JP. The concept of allosteric interaction and its consequences for the chemistry of the brain. J Biol Chem 2013; Jul 22. [Epub ahead of print].
-
(2013)
J Biol Chem
-
-
Changeux, J.P.1
-
55
-
-
84876417485
-
Cooperativity of allosteric receptors
-
Edelstein SJ, Le Novère N. Cooperativity of allosteric receptors. J Mol Biol 2013; 425: 1424-32.
-
(2013)
J Mol Biol
, vol.425
, pp. 1424-1432
-
-
Edelstein, S.J.1
Le Novère, N.2
-
56
-
-
59649090731
-
A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides
-
Liu Q, Huang Y, Xue F, et al. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. J Neurosci 2009; 29: 918-29.
-
(2009)
J Neurosci
, vol.29
, pp. 918-929
-
-
Liu, Q.1
Huang, Y.2
Xue, F.3
-
57
-
-
84871543510
-
Functional α7β2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid peptides
-
Liu Q, Huang Y, Shen J, Steffensen S, Wu J. Functional α7β2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid peptides. BMC Neurosci 2012; 13: 155.
-
(2012)
BMC Neurosci
, vol.13
, pp. 155
-
-
Liu, Q.1
Huang, Y.2
Shen, J.3
Steffensen, S.4
Wu, J.5
-
58
-
-
84878891156
-
Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex
-
Wallace TL, Bertrand D. Importance of the nicotinic acetylcholine receptor system in the prefrontal cortex. Biochem Pharmacol 2013; 85: 1713-20.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 1713-1720
-
-
Wallace, T.L.1
Bertrand, D.2
-
59
-
-
80051605646
-
Nicotinic acetylcholine receptor r2 subunits in the medial prefrontal cortex control attention
-
Guillem K, Bloem B, Poorthuis RB, et al. Nicotinic acetylcholine receptor r2 subunits in the medial prefrontal cortex control attention. Science 2011; 333: 888-91.
-
(2011)
Science
, vol.333
, pp. 888-891
-
-
Guillem, K.1
Bloem, B.2
Poorthuis, R.B.3
-
60
-
-
42049093762
-
Alpha7 nicotinic acetylcholine receptor gene and reduced risk of Alzheimer's disease
-
Carson R, Craig D, McGuinness B, et al. Alpha7 nicotinic acetylcholine receptor gene and reduced risk of Alzheimer's disease. J Med Genet 2008; 45: 244-8.
-
(2008)
J Med Genet
, vol.45
, pp. 244-248
-
-
Carson, R.1
Craig, D.2
McGuinness, B.3
-
61
-
-
0028140507
-
Molecular cloning and chromosomal localization of the human alpha 7-nicotinic receptor subunit gene (CHRNA7)
-
Chini B, Raimond E, Elgoyhen AB, et al. Molecular cloning and chromosomal localization of the human alpha 7-nicotinic receptor subunit gene (CHRNA7). Genomics. 1994; 19: 379-81.
-
(1994)
Genomics
, vol.19
, pp. 379-381
-
-
Chini, B.1
Raimond, E.2
Elgoyhen, A.B.3
-
62
-
-
0035704937
-
A 3-Mb map of a large Segmental duplication overlapping the alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human 15q13-q14
-
Riley B, Williamson M, Collier D, Wilkie H, Makoff A. A 3-Mb map of a large Segmental duplication overlapping the alpha7-nicotinic acetylcholine receptor gene (CHRNA7) at human 15q13-q14. Genomics 2002; 79: 197-209.
-
(2002)
Genomics
, vol.79
, pp. 197-209
-
-
Riley, B.1
Williamson, M.2
Collier, D.3
Wilkie, H.4
Makoff, A.5
-
63
-
-
54549093676
-
The copy number variant involving part of the alpha 7 nicotinic receptor gene contains a polymorphic inversion
-
Flomen RH, Davies AF, Di Forti M, et al. The copy number variant involving part of the alpha 7 nicotinic receptor gene contains a polymorphic inversion. Eur J Hum Gen 2008; 16: 1364-71.
-
(2008)
Eur J Hum Gen
, vol.16
, pp. 1364-1371
-
-
Flomen, R.H.1
Davies, A.F.2
Di Forti, M.3
-
64
-
-
0036428860
-
The-2 bp deletion in exon 6 of the 'alpha 7-like' nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit
-
Raux G, Bonnet-Brilhault F, Louchart S, et al. The-2 bp deletion in exon 6 of the 'alpha 7-like' nicotinic receptor subunit gene is a risk factor for the P50 sensory gating deficit. Mol Psych 2002; 7: 1006-11.
-
(2002)
Mol Psych
, vol.7
, pp. 1006-1011
-
-
Raux, G.1
Bonnet-Brilhault, F.2
Louchart, S.3
-
65
-
-
80052026366
-
The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function
-
Araud T, Graw S, Berger R, et al. The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function. Biochem Pharmacol 2011; 82: 904-14.
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 904-914
-
-
Araud, T.1
Graw, S.2
Berger, R.3
-
66
-
-
67651208215
-
Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia
-
Fehér A, Juhász A, Rimanóczy A, et al. Association between a genetic variant of the alpha-7 nicotinic acetylcholine receptor subunit and four types of dementia. Dement Geriatr Cogn Disord 2009; 28: 56-62.
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, pp. 56-62
-
-
Fehér, A.1
Juhász, A.2
Rimanóczy, A.3
-
67
-
-
84860452492
-
Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia
-
Neri M, Bonassi S, Russo P. Genetic variations in CHRNA7 or CHRFAM7 and susceptibility to dementia. Curr Drug Targets 2012; 13: 636-43.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 636-643
-
-
Neri, M.1
Bonassi, S.2
Russo, P.3
-
68
-
-
84872295116
-
Nicotinic acetylcholine receptors: From basic science to therapeutics
-
Hurst R, Rollema H, Bertrand D. Nicotinic acetylcholine receptors: from basic science to therapeutics. Pharmacol Ther 2013; 137: 22-54.
-
(2013)
Pharmacol Ther
, vol.137
, pp. 22-54
-
-
Hurst, R.1
Rollema, H.2
Bertrand, D.3
-
69
-
-
0037122918
-
PRiMA: The membrane anchor of acetylcholinesterase in the brain
-
Perrier AL, Massoulie J, Krejci E. PRiMA: the membrane anchor of acetylcholinesterase in the brain. Neuron 2002; 33: 275-85.
-
(2002)
Neuron
, vol.33
, pp. 275-285
-
-
Perrier, A.L.1
Massoulie, J.2
Krejci, E.3
-
71
-
-
0030036594
-
New local anesthetic agents
-
Gyermek L. New local anesthetic agents. Anesthesiology. 1996; 85: 226-227.
-
(1996)
Anesthesiology
, vol.85
, pp. 226-227
-
-
Gyermek, L.1
-
72
-
-
0018772249
-
Numerical reconstruction of the quantal event at nicotinic synapses
-
Wathey JC, Nass MN, Lester H. A. Numerical reconstruction of the quantal event at nicotinic synapses. Biophys. J. 1979; 27: 145-64.
-
(1979)
Biophys J
, vol.27
, pp. 145-164
-
-
Wathey, J.C.1
Nass, M.N.2
Lester, H.A.3
-
73
-
-
0025780592
-
Monte-Carlo simulation of miniature end-plate current generation in the vertebrate neuromuscular junction
-
Bartol TM, Land BR, Salpeter EE, Salpeter MM. Monte-Carlo simulation of miniature end-plate current generation in the vertebrate neuromuscular junction. Biophys J. 1991; 59: 1290-1307.
-
(1991)
Biophys J
, vol.59
, pp. 1290-1307
-
-
Bartol, T.M.1
Land, B.R.2
Salpeter, E.E.3
Salpeter, M.M.4
-
74
-
-
59649098711
-
Desensitization of nicotinic acetylcholine receptors as a strategy for drug development
-
Buccafusco JJ, Beach JW, Terry AV Jr. Desensitization of nicotinic acetylcholine receptors as a strategy for drug development. J Pharmacol Exp Ther 2009, 328: 364-70.
-
(2009)
J Pharmacol Exp Ther
, vol.328
, pp. 364-370
-
-
Buccafusco, J.J.1
Beach, J.W.2
Terry, A.V.3
-
75
-
-
80054915952
-
Tobacco habit: Historical, cultural, neurobiological, and genetic features of people's relationship with an addictive drug
-
Russo P, Nastrucci C, Alzetta G, Szalai C. Tobacco habit: historical, cultural, neurobiological, and genetic features of people's relationship with an addictive drug. Perspect Biol Med 2011; 54: 557-77.
-
(2011)
Perspect Biol Med
, vol.54
, pp. 557-577
-
-
Russo, P.1
Nastrucci, C.2
Alzetta, G.3
Szalai, C.4
-
76
-
-
84555217924
-
Nicotine: Specific role in angiogenesis, proliferation and apoptosis
-
Cardinale A, Nastrucci C, Cesario A, Russo P. Nicotine: specific role in angiogenesis, proliferation and apoptosis. Crit Rev Toxicol 2012; 42: 68-89.
-
(2012)
Crit Rev Toxicol
, vol.42
, pp. 68-89
-
-
Cardinale, A.1
Nastrucci, C.2
Cesario, A.3
Russo, P.4
-
77
-
-
0023683671
-
Nicotine enhances delayed matching-to sample performance by primates
-
Elrod K, Buccafusco JJ, Jackson WJ. Nicotine enhances delayed matching-to sample performance by primates. Life Sci 1988; 43: 277-87.
-
(1988)
Life Sci
, vol.43
, pp. 277-287
-
-
Elrod, K.1
Buccafusco, J.J.2
Jackson, W.J.3
-
78
-
-
0025780198
-
Beneficial effects of nicotine administered prior to a delayed matching-to-sample task in young and aged monkeys
-
Buccafusco JJ, Jackson WJ. Beneficial effects of nicotine administered prior to a delayed matching-to-sample task in young and aged monkeys. Neurobiol Aging. 1991; 12: 233-8.
-
(1991)
Neurobiol Aging
, vol.12
, pp. 233-238
-
-
Buccafusco, J.J.1
Jackson, W.J.2
-
79
-
-
84864837339
-
Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial
-
Newhouse P, Kellar K, Aisen P, et al. Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. Neurology 2012; 78: 91-101.
-
(2012)
Neurology
, vol.78
, pp. 91-101
-
-
Newhouse, P.1
Kellar, K.2
Aisen, P.3
-
80
-
-
84925856938
-
-
(Accessed July 28, 2013)
-
http://www. alz. org/national/documents/topicsheet_mci. pdf. (Accessed July 28, 2013).
-
-
-
-
81
-
-
63849147368
-
Nicotine chemistry, metabolism, kinetics and biomarkers
-
Benowitz NL, Hukkanen J, Jacob P 3rd. Nicotine chemistry, metabolism, kinetics and biomarkers. Handb Exp Pharmacol 2009; 192: 29-60.
-
(2009)
Handb Exp Pharmacol
, vol.192
, pp. 29-60
-
-
Benowitz, N.L.1
Hukkanen, J.2
Jacob, P.3
-
82
-
-
0000373886
-
Studies on the metabolism of (-)-cotinine in the human
-
Bowman ER, Mc KH Jr. Studies on the metabolism of (-)-cotinine in the human. J. Pharmacol. Exp. Ther. 1962; 135: 306-11.
-
(1962)
J. Pharmacol. Exp Ther
, vol.135
, pp. 306-311
-
-
Bowman, E.R.1
Mc, K.H.2
-
83
-
-
0021083598
-
Cotinine disposition and effects
-
Benowitz NL, Kuyt F, Jacob P III, Jones R T, Osman A. Cotinine disposition and effects. Clin. Pharmacol. Ther. 1983; 34: 604-11.
-
(1983)
Clin. Pharmacol Ther
, vol.34
, pp. 604-611
-
-
Benowitz, N.L.1
Kuyt, F.2
Jacob P, I.I.I.3
Jones, R.T.4
Osman, A.5
-
84
-
-
84870755541
-
Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption
-
Moran VE. Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption. Front Pharmacol 2012; 3: 173.
-
(2012)
Front Pharmacol
, vol.3
, pp. 173
-
-
Moran, V.E.1
-
85
-
-
84860461624
-
α7 nicotinic acetylcholine receptors: A therapeutic target in the structure era
-
Taly A, Charon S. α7 nicotinic acetylcholine receptors: a therapeutic target in the structure era. Curr Drug Targets 2012; 13: 695-706.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 695-706
-
-
Taly, A.1
Charon, S.2
-
86
-
-
84860456578
-
The α7 nicotinic acetylcholine receptor complex: One, two or multiple drug targets?
-
Thomsen MS, Mikkelsen JD. The α7 nicotinic acetylcholine receptor complex: one, two or multiple drug targets? Curr Drug Targets 2012, 13: 707-20.
-
(2012)
Curr Drug Targets
, vol.13
, pp. 707-720
-
-
Thomsen, M.S.1
Mikkelsen, J.D.2
-
87
-
-
77954584878
-
Alpha7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease
-
Toyohara J, Hashimoto K. alpha7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease. The Open Med Chem Journ 2010; 4: 37-56.
-
(2010)
The Open Med Chem Journ
, vol.4
, pp. 37-56
-
-
Toyohara, J.1
Hashimoto, K.2
-
88
-
-
84866373219
-
The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus monkeys
-
Cannon CE, Puri V, Vivian JA, et al. The nicotinic α7 receptor agonist GTS-21 improves cognitive performance in ketamine impaired rhesus monkeys. Neuropharmacol 2013; 64: 191-6.
-
(2013)
Neuropharmacol
, vol.64
, pp. 191-196
-
-
Cannon, C.E.1
Puri, V.2
Vivian, J.A.3
-
89
-
-
0031003185
-
Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21. In vitro and in vivo
-
Briggs CA, Anderson DJ, Brioni JD, et al. Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21. In vitro and in vivo. Pharmacol Biochem Behav. 1997; 57: 231-41.
-
(1997)
Pharmacol Biochem Behav
, vol.57
, pp. 231-241
-
-
Briggs, C.A.1
Anderson, D.J.2
Brioni, J.D.3
-
90
-
-
0038690569
-
Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers
-
Kitagawa H, Takenouchi T, Azuma R, et al. Safety, pharmacokinetics, and effects on cognitive function of multiple doses of GTS-21 in healthy, male volunteers. Neuropsychopharmacol 2003; 28: 542-51.
-
(2003)
Neuropsychopharmacol
, vol.28
, pp. 542-551
-
-
Kitagawa, H.1
Takenouchi, T.2
Azuma, R.3
-
91
-
-
33744911665
-
Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia
-
Olincy A, Harris JG, Johnson LL, et al. Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Arch Gen Psychiatry 2006; 63: 630-8.
-
(2006)
Arch Gen Psychiatry
, vol.63
, pp. 630-638
-
-
Olincy, A.1
Harris, J.G.2
Johnson, L.L.3
-
92
-
-
84925873907
-
-
(Accessed July 28, 2013)
-
http://www. clinicaltrials. gov/ct2/show/NCT00414622. (Accessed July 28, 2013).
-
-
-
-
93
-
-
84925860374
-
In vitro pharmacological characterization of a novel selective alpha 7 neuronal nicotinic acetylcholine receptor agonist ABT-107
-
October 17-21, Chicago, Ill
-
Malysz J, Anderson DJ, Gronlien JH, Ji J, et al. In vitro pharmacological characterization of a novel selective alpha 7 neuronal nicotinic acetylcholine receptor agonist ABT-107. 39th Annual Meeting of Society for Neuroscience (SFN); October 17-21, 2009; Chicago, Ill.
-
(2009)
39th Annual Meeting of Society for Neuroscience (SFN)
-
-
Malysz, J.1
Anderson, D.J.2
Gronlien, J.H.3
Ji, J.4
-
94
-
-
79953779271
-
Single-and multiple-dose pharmacokinetics, safety and tolerability of the selective alpha7 neuronal nicotinic receptor agonist, ABT-107 in healthy human volunteers
-
Othman AA, Lenz RA, Zhang J, et al. Single-and multiple-dose pharmacokinetics, safety and tolerability of the selective alpha7 neuronal nicotinic receptor agonist, ABT-107, in healthy human volunteers J Clin Pharmacol 2011; 51: 512-26.
-
(2011)
J Clin Pharmacol
, vol.51
, pp. 512-526
-
-
Othman, A.A.1
Lenz, R.A.2
Zhang, J.3
-
95
-
-
84925870919
-
-
(Accessed July 28, 2013)
-
http://clinicaltrials. gov/ct2/results?term=NCT01549834. (Accessed July 28, 2013).
-
-
-
-
96
-
-
84855964150
-
EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors
-
Prickaerts J, van Goethem NP, Chesworth R, et al. EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors. Neuropharmacol 2012; 62: 1099-110.
-
(2012)
Neuropharmacol
, vol.62
, pp. 1099-1110
-
-
Prickaerts, J.1
van Goethem, N.P.2
Chesworth, R.3
-
97
-
-
84925843382
-
-
(Accessed July 28, 2013)
-
http://www. envivopharma. com/pdf/EVP-6124AAICPressConf. pdf. (Accessed July 28, 2013).
-
-
-
-
98
-
-
84925860159
-
-
(Accessed July 28, 2013)
-
http://www. envivopharma. com/news-item. php?id=45. (Accessed July 28, 2013).
-
-
-
-
99
-
-
78650797928
-
RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents
-
Wallace TL, Callahan PM, Tehim A, et al. RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents. J Pharmacol Exp Ther 2011; 336: 242-53.
-
(2011)
J Pharmacol Exp Ther
, vol.336
, pp. 242-253
-
-
Wallace, T.L.1
Callahan, P.M.2
Tehim, A.3
-
100
-
-
84925870323
-
-
(Accessed July 28, 2013)
-
http://clinicaltrials. gov/ct2/results?term=NCT00582855. (Accessed July 28, 2013).
-
-
-
-
101
-
-
84925864605
-
-
(Accessed July 28, 2013)
-
http://www. drugs. com/clinical_trials/memory-pharmaceuticalsannounces-positive-phase-2a-results-mem-3454-alzheimer-s-2538. html. (Accessed July 28, 2013).
-
-
-
-
102
-
-
84925879243
-
-
(Accessed July 28, 2013)
-
http://sigma. larvol. com/merge/sigma/trialzilla_product. php? e1=306&sourcepg=TZP. (Accessed July 28, 2013).
-
-
-
-
103
-
-
84925870191
-
-
(Accessed July 28, 2013)
-
http://www. clinicaltrials. gov/ct2/results?term=AQW051& Search=Search. (Accessed July 28, 2013).
-
-
-
-
104
-
-
84925848995
-
-
(Accessed July 28, 2013)
-
http://clinicaltrials. gov/ct2/results?term=NCT00582855. (Accessed July 28, 2013).
-
-
-
-
105
-
-
84870006985
-
Discovery of (2S,3R)-N-[2-(pyridin-3-ylmethyl)-1-azabicyclo[2. 2. 2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a selective α7 nicotinic acetylcholine receptor agonist, for the treatment of cognitive disorders
-
Mazurov AA, Kombo DC, Hauser TA, et al. Discovery of (2S,3R)-N-[2-(pyridin-3-ylmethyl)-1-azabicyclo[2. 2. 2]oct-3-yl]benzo[b]furan-2-carboxamide (TC-5619), a selective α7 nicotinic acetylcholine receptor agonist, for the treatment of cognitive disorders. J Med Chem 2012; 55: 9793-809.
-
(2012)
J Med Chem
, vol.55
, pp. 9793-9809
-
-
Mazurov, A.A.1
Kombo, D.C.2
Hauser, T.A.3
-
106
-
-
84925847087
-
-
(Accessed July 28, 2013)
-
http://clinicaltrials. gov/ct2/results?term=NCT01254448 (Accessed July 28, 2013).
-
-
-
-
107
-
-
33747044365
-
Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade
-
Takada-Takatori Y, Kume T, Sugimoto M, et al. Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphatidylinositol 3-kinase cascade. Neuropharmacol 2006; 51: 474-86.
-
(2006)
Neuropharmacol
, vol.51
, pp. 474-486
-
-
Takada-Takatori, Y.1
Kume, T.2
Sugimoto, M.3
-
108
-
-
48049111171
-
Mechanisms of alpha7-nicotinic receptor up-regulation and sensitization to Donepezil induced by chronic Donepezil treatment
-
Takada-Takatori Y, Kume T, Ohgi Y, et al. Mechanisms of alpha7-nicotinic receptor up-regulation and sensitization to Donepezil induced by chronic Donepezil treatment. Eur J Pharmacol 2008; 590: 150-6.
-
(2008)
Eur J Pharmacol
, vol.590
, pp. 150-156
-
-
Takada-Takatori, Y.1
Kume, T.2
Ohgi, Y.3
-
109
-
-
73449105029
-
Cholinergic protection via alpha7 nicotinic acetylcholine receptors and PI3K-Akt pathway in LPS-induced neuroinflammation
-
Tyagi E, Agrawal R, Nath C, Shukla R. Cholinergic protection via alpha7 nicotinic acetylcholine receptors and PI3K-Akt pathway in LPS-induced neuroinflammation. Neurochem Int 2010; 56: 135-42.
-
(2010)
Neurochem Int
, vol.56
, pp. 135-142
-
-
Tyagi, E.1
Agrawal, R.2
Nath, C.3
Shukla, R.4
-
110
-
-
84864491691
-
Okadaic acid induced neurotoxicity leads to central cholinergic dysfunction in rats
-
Kamat PK, Tota S, Rai S, et al. Okadaic acid induced neurotoxicity leads to central cholinergic dysfunction in rats. Eur J Pharmacol 2012; 690: 90-8.
-
(2012)
Eur J Pharmacol
, vol.690
, pp. 90-98
-
-
Kamat, P.K.1
Tota, S.2
Rai, S.3
-
111
-
-
0032810628
-
Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices
-
Frankiewicz T, Parsons CG. Memantine restores long term potentiation impaired by tonic N-methyl-D-aspartate (NMDA) receptor activation following reduction of Mg2+ in hippocampal slices. Neuropharmacol. 1999; 38: 1253-59.
-
(1999)
Neuropharmacol
, vol.38
, pp. 1253-1259
-
-
Frankiewicz, T.1
Parsons, C.G.2
-
112
-
-
1642422286
-
Inhibition of human h7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors
-
Maskell PD, Speder P, Newberry NR, Bermudez I. Inhibition of human h7 nicotinic acetylcholine receptors by open channel blockers of N-methyl-D-aspartate receptors. Br J Pharmacol 2003; 140: 1313-19.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1313-1319
-
-
Maskell, P.D.1
Speder, P.2
Newberry, N.R.3
Bermudez, I.4
-
113
-
-
0029085113
-
Cerebrospinal fluid and serum concentrations of the N-methyl-D-aspartate (NMDA) receptor antagonist Memantine in man
-
Kornhuber J, Quack G. Cerebrospinal fluid and serum concentrations of the N-methyl-D-aspartate (NMDA) receptor antagonist Memantine in man. Neurosci Lett. 1995; 195: 137-39.
-
(1995)
Neurosci Lett
, vol.195
, pp. 137-139
-
-
Kornhuber, J.1
Quack, G.2
-
114
-
-
0141707078
-
The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: Preclinical evidence
-
Danysz W, Parsons CG. The NMDA receptor antagonist memantine as a symptomatological and neuroprotective treatment for Alzheimer's disease: preclinical evidence. Int J Geriatr Psychiatry 2003; 18: S23-32.
-
(2003)
Int J Geriatr Psychiatry
, vol.18
, pp. 23-32
-
-
Danysz, W.1
Parsons, C.G.2
-
115
-
-
84878400011
-
Nicotinic acetylcholine receptors contribute to learning-induced metaplasticity in the hippocampus
-
Becker B, Klein EM, Striepens N, et al. Nicotinic acetylcholine receptors contribute to learning-induced metaplasticity in the hippocampus. J Cogn Neurosci 2013; 25: 986-97.
-
(2013)
J Cogn Neurosci
, vol.25
, pp. 986-997
-
-
Becker, B.1
Klein, E.M.2
Striepens, N.3
-
116
-
-
84868117094
-
Pittsburgh compound B and the postmortem diagnosis of Alzheimer disease
-
Niedowicz DM, Beckett TL, Matveev S, et al. Pittsburgh compound B and the postmortem diagnosis of Alzheimer disease. Ann Neurol 2012; 72: 564-70.
-
(2012)
Ann Neurol
, vol.72
, pp. 564-570
-
-
Niedowicz, D.M.1
Beckett, T.L.2
Matveev, S.3
-
117
-
-
79955008177
-
Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site
-
Gill JK, Savolainen M, Young GT, et al. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site. Proc Natl Acad Sci USA 2011; 108: 5867-72.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 5867-5872
-
-
Gill, J.K.1
Savolainen, M.2
Young, G.T.3
-
118
-
-
84859949261
-
A series of [7 nicotinic acetylcholine receptor allosteric modulators with close chemical similarity but diverse pharmacological properties
-
Gill JK, Dhankher P, Sheppard TD, Sher E, Millar NS. A series of [7 nicotinic acetylcholine receptor allosteric modulators with close chemical similarity but diverse pharmacological properties. Mol Pharmacol 2012; 81: 710-18.
-
(2012)
Mol Pharmacol
, vol.81
, pp. 710-718
-
-
Gill, J.K.1
Dhankher, P.2
Sheppard, T.D.3
Sher, E.4
Millar, N.S.5
-
119
-
-
0028984453
-
1995. Physosotigmine, galantamine and codeine act as noncompetitive nicotinic receptor agonists on clonal rat pheochromocytoma cells
-
Storch A, Schrattenholz A, Cooper JC, et al. 1995. Physosotigmine, galantamine and codeine act as noncompetitive nicotinic receptor agonists on clonal rat pheochromocytoma cells. Eur J Pharmacol. 1995; 290: 207-19.
-
(1995)
Eur J Pharmacol
, vol.290
, pp. 207-219
-
-
Storch, A.1
Schrattenholz, A.2
Cooper, J.C.3
-
120
-
-
10744232323
-
Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors
-
Samochocki M, Höffle A, Fehrenbacher A, et al. Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors. J Pharmacol Exp Ther 2003, 305: 1024-36.
-
(2003)
J Pharmacol Exp Ther
, vol.305
, pp. 1024-1036
-
-
Samochocki, M.1
Höffle, A.2
Fehrenbacher, A.3
-
121
-
-
33644658662
-
The clinical and costeffectiveness of Donepezil, rivastigmine, galantamine and Memantine for Alzheimer's disease
-
Loveman E, Green C, Kirby J, et al. The clinical and costeffectiveness of Donepezil, rivastigmine, galantamine and Memantine for Alzheimer's disease. Health Technol Assess 2006; 10: 1-160.
-
(2006)
Health Technol Assess
, vol.10
, pp. 1-160
-
-
Loveman, E.1
Green, C.2
Kirby, J.3
-
122
-
-
84862619683
-
The effectiveness and costeffectiveness of Donepezil, galantamine, rivastigmine and Memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): A systematic review and economic model
-
Bond M, Rogers G, Peters J, et al. The effectiveness and costeffectiveness of Donepezil, galantamine, rivastigmine and Memantine for the treatment of Alzheimer's disease (review of Technology Appraisal No. 111): a systematic review and economic model. Health Technol Assess 2012; 16: 1-470.
-
(2012)
Health Technol Assess
, vol.16
, pp. 1-470
-
-
Bond, M.1
Rogers, G.2
Peters, J.3
-
123
-
-
33645510613
-
Galantamine for Alzheimer's disease and mild cognitive impairment
-
Loy C, Schneider L. Galantamine for Alzheimer's disease and mild cognitive impairment. Cochrane Database Syst Rev 2006; 1: CD001747.
-
(2006)
Cochrane Database Syst Rev
, vol.1
-
-
Loy, C.1
Schneider, L.2
-
124
-
-
0034569152
-
Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR
-
Samochocki M, Zerlin M, Jostock R, et al. Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR. Acta Neurol Scand Suppl 2000; 176: 68-73.
-
(2000)
Acta Neurol Scand Suppl
, vol.176
, pp. 68-73
-
-
Samochocki, M.1
Zerlin, M.2
Jostock, R.3
-
125
-
-
78649640881
-
Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain
-
Ludwig J, Höffle-Maas A, Samochocki M, et al. Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain. J Recept Signal Transduct Res 2010; 30: 469-83.
-
(2010)
J Recept Signal Transduct Res
, vol.30
, pp. 469-483
-
-
Ludwig, J.1
Höffle-Maas, A.2
Samochocki, M.3
-
126
-
-
79953325912
-
Pharmaco-genetically guided treatment of recurrent rage outbursts in an adult male with 15q13.3 deletion syndrome
-
Cubells JF, Deoreo EH, Harvey PD, et al. Pharmaco-genetically guided treatment of recurrent rage outbursts in an adult male with 15q13. 3 deletion syndrome. Am J Med Genet A 2011; 155A: 805-10.
-
(2011)
Am J Med Genet A
, vol.155 A
, pp. 805-810
-
-
Cubells, J.F.1
Deoreo, E.H.2
Harvey, P.D.3
-
127
-
-
67449114040
-
Microdeletion 15q13. 3: A locus with incomplete penetrance for autism, mental retardation, and psychiatric disorders
-
Ben-Shachar S, Lanpher B, German JR, et al. Microdeletion 15q13. 3: A locus with incomplete penetrance for autism, mental retardation, and psychiatric disorders. J Med Genet 2009; 46: 382-8.
-
(2009)
J Med Genet
, vol.46
, pp. 382-388
-
-
Ben-Shachar, S.1
Lanpher, B.2
German, J.R.3
-
128
-
-
84881027906
-
Targeting alpha-7 nicotinic neurotransmission in schizophrenia: A novel agonist strategy
-
Jun 12. [Epub ahead of print]
-
Deutsch SI, Schwartz BL, Schooler NR, et al. Targeting alpha-7 nicotinic neurotransmission in schizophrenia: A novel agonist strategy. Schizophr Res 2013 Jun 12. [Epub ahead of print].
-
(2013)
Schizophr Res
-
-
Deutsch, S.I.1
Schwartz, B.L.2
Schooler, N.R.3
-
129
-
-
84885652983
-
Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies
-
May 31
-
Pandya AA, Yakel JL. Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies. Biochem Pharmacol 2013 May 31.
-
(2013)
Biochem Pharmacol
-
-
Pandya, A.A.1
Yakel, J.L.2
|