-
1
-
-
67651180986
-
The amyloid hypothesis for Alzheimer's disease: A critical reappraisal
-
Hardy J,. The amyloid hypothesis for Alzheimer's disease: a critical reappraisal. J Neurochem 2009; 110: 1129-1134.
-
(2009)
J Neurochem
, vol.110
, pp. 1129-1134
-
-
Hardy, J.1
-
3
-
-
0030681215
-
The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease
-
Consensus recommendations for the postmortem diagnosis of Alzheimer's disease.
-
Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Neurobiol Aging 1997; 18 (4 suppl): S1-S2.
-
(1997)
Neurobiol Aging
, vol.18
, Issue.4 SUPPL.
-
-
-
4
-
-
0035997249
-
Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins
-
Atwood CS, Martins RN, Smith MA, Perry G,. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides 2002; 23: 1343-1350.
-
(2002)
Peptides
, vol.23
, pp. 1343-1350
-
-
Atwood, C.S.1
Martins, R.N.2
Smith, M.A.3
Perry, G.4
-
5
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
Haass C, Selkoe DJ,. Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 2007; 8: 101-112.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
6
-
-
49149124343
-
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
-
Shankar GM, Li S, Mehta TH, et al. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med 2008; 14: 837-842.
-
(2008)
Nat Med
, vol.14
, pp. 837-842
-
-
Shankar, G.M.1
Li, S.2
Mehta, T.H.3
-
7
-
-
34548253353
-
Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice
-
Murphy MP, Beckett TL, Ding Q, et al. Abeta solubility and deposition during AD progression and in APPxPS-1 knock-in mice. Neurobiol Dis 2007; 27: 301-311.
-
(2007)
Neurobiol Dis
, vol.27
, pp. 301-311
-
-
Murphy, M.P.1
Beckett, T.L.2
Ding, Q.3
-
8
-
-
37349096335
-
Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: Neuritic plaques and neurofibrillary tangles "do count" when staging disease severity
-
Nelson PT, Jicha GA, Schmitt FA, et al. Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity. J Neuropathol Exp Neurol 2007; 66: 1136-1146.
-
(2007)
J Neuropathol Exp Neurol
, vol.66
, pp. 1136-1146
-
-
Nelson, P.T.1
Jicha, G.A.2
Schmitt, F.A.3
-
9
-
-
70350152831
-
Relationships between biomarkers in aging and dementia
-
Jagust WJ, Landau SM, Shaw LM, et al. Relationships between biomarkers in aging and dementia. Neurology 2009; 73: 1193-1199.
-
(2009)
Neurology
, vol.73
, pp. 1193-1199
-
-
Jagust, W.J.1
Landau, S.M.2
Shaw, L.M.3
-
10
-
-
16544371922
-
Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease
-
Wang Y, Klunk WE, Debnath ML, et al. Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease. J Mol Neurosci 2004; 24: 55-62.
-
(2004)
J Mol Neurosci
, vol.24
, pp. 55-62
-
-
Wang, Y.1
Klunk, W.E.2
Debnath, M.L.3
-
11
-
-
10744232413
-
Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B
-
Klunk WE, Engler H, Nordberg A, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann Neurol 2004; 55: 306-319.
-
(2004)
Ann Neurol
, vol.55
, pp. 306-319
-
-
Klunk, W.E.1
Engler, H.2
Nordberg, A.3
-
12
-
-
70349860185
-
Clinical severity of Alzheimer's disease is associated with PIB uptake in PET
-
Grimmer T, Henriksen G, Wester HJ, et al. Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. Neurobiol Aging 2009; 30: 1902-1909.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1902-1909
-
-
Grimmer, T.1
Henriksen, G.2
Wester, H.J.3
-
13
-
-
77954033982
-
3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects
-
Apostolova LG, Hwang KS, Andrawis JP, et al. 3D PIB and CSF biomarker associations with hippocampal atrophy in ADNI subjects. Neurobiol Aging 2010; 31: 1284-1303.
-
(2010)
Neurobiol Aging
, vol.31
, pp. 1284-1303
-
-
Apostolova, L.G.1
Hwang, K.S.2
Andrawis, J.P.3
-
14
-
-
0037444535
-
The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component
-
Klunk WE, Wang Y, Huang GF, et al. The binding of 2-(4'- methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component. J Neurosci 2003; 23: 2086-2092.
-
(2003)
J Neurosci
, vol.23
, pp. 2086-2092
-
-
Klunk, W.E.1
Wang, Y.2
Huang, G.F.3
-
15
-
-
27944471285
-
Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain
-
Klunk WE, Lopresti BJ, Ikonomovic MD, et al. Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain. J Neurosci 2005; 25: 10598-10606.
-
(2005)
J Neurosci
, vol.25
, pp. 10598-10606
-
-
Klunk, W.E.1
Lopresti, B.J.2
Ikonomovic, M.D.3
-
16
-
-
33947198109
-
Molecular imaging with Pittsburgh compound B confirmed at autopsy: A case report
-
Bacskai BJ, Frosch MP, Freeman SH, et al. Molecular imaging with Pittsburgh compound B confirmed at autopsy: a case report. Arch Neurol 2007; 64: 431-434.
-
(2007)
Arch Neurol
, vol.64
, pp. 431-434
-
-
Bacskai, B.J.1
Frosch, M.P.2
Freeman, S.H.3
-
17
-
-
43849083580
-
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
-
Ikonomovic MD, Klunk WE, Abrahamson EE, et al. Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease. Brain 2008; 131 (pt 6): 1630-1645.
-
(2008)
Brain
, vol.131
, Issue.PART 6
, pp. 1630-1645
-
-
Ikonomovic, M.D.1
Klunk, W.E.2
Abrahamson, E.E.3
-
18
-
-
54049120245
-
Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh compound B
-
Leinonen V, Alafuzoff I, Aalto S, et al. Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh compound B. Arch Neurol 2008; 65: 1304-1309.
-
(2008)
Arch Neurol
, vol.65
, pp. 1304-1309
-
-
Leinonen, V.1
Alafuzoff, I.2
Aalto, S.3
-
19
-
-
0035209157
-
Brain donation in normal aging: Procedures, motivations, and donor characteristics from the Biologically Resilient Adults in Neurological Studies (BRAiNS) Project
-
Schmitt FA, Wetherby MM, Wekstein DR, et al. Brain donation in normal aging: procedures, motivations, and donor characteristics from the Biologically Resilient Adults in Neurological Studies (BRAiNS) Project. Gerontologist 2001; 41: 716-722.
-
(2001)
Gerontologist
, vol.41
, pp. 716-722
-
-
Schmitt, F.A.1
Wetherby, M.M.2
Wekstein, D.R.3
-
20
-
-
71549156298
-
Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons
-
Nelson PT, Abner EL, Schmitt FA, et al. Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathol 2010; 20: 66-79.
-
(2010)
Brain Pathol
, vol.20
, pp. 66-79
-
-
Nelson, P.T.1
Abner, E.L.2
Schmitt, F.A.3
-
21
-
-
0033845932
-
"Preclinical" AD revisited: Neuropathology of cognitively normal older adults
-
Schmitt FA, Davis DG, Wekstein DR, et al. "Preclinical" AD revisited: neuropathology of cognitively normal older adults. Neurology 2000; 55: 370-376.
-
(2000)
Neurology
, vol.55
, pp. 370-376
-
-
Schmitt, F.A.1
Davis, D.G.2
Wekstein, D.R.3
-
22
-
-
30344469658
-
Neuropathologic substrate of mild cognitive impairment
-
Markesbery WR, Schmitt FA, Kryscio RJ, et al. Neuropathologic substrate of mild cognitive impairment. Arch Neurol 2006; 63: 38-46.
-
(2006)
Arch Neurol
, vol.63
, pp. 38-46
-
-
Markesbery, W.R.1
Schmitt, F.A.2
Kryscio, R.J.3
-
23
-
-
0025863618
-
Neuropathological staging of Alzheimer-related changes
-
Braak H, Braak E,. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991; 82: 239-259.
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
24
-
-
77954959100
-
Effects of nonsteroidal anti-inflammatory drugs on amyloid-beta pathology in mouse skeletal muscle
-
Beckett TL, Niedowicz DM, Studzinski CM, et al. Effects of nonsteroidal anti-inflammatory drugs on amyloid-beta pathology in mouse skeletal muscle. Neurobiol Dis 2010; 39: 449-456.
-
(2010)
Neurobiol Dis
, vol.39
, pp. 449-456
-
-
Beckett, T.L.1
Niedowicz, D.M.2
Studzinski, C.M.3
-
25
-
-
0141457897
-
Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice
-
Das P, Howard V, Loosbrock N, et al. Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice. J Neurosci 2003; 23: 8532-8538.
-
(2003)
J Neurosci
, vol.23
, pp. 8532-8538
-
-
Das, P.1
Howard, V.2
Loosbrock, N.3
-
26
-
-
22544482926
-
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice
-
McGowan E, Pickford F, Kim J, et al. Abeta42 is essential for parenchymal and vascular amyloid deposition in mice. Neuron 2005; 47: 191-199.
-
(2005)
Neuron
, vol.47
, pp. 191-199
-
-
McGowan, E.1
Pickford, F.2
Kim, J.3
-
27
-
-
80052934408
-
RNA oxidation adducts 8-OHG and 8-OHA change with Abeta(42) levels in late-stage Alzheimer's disease
-
Weidner AM, Bradley MA, Beckett TL, et al. RNA oxidation adducts 8-OHG and 8-OHA change with Abeta(42) levels in late-stage Alzheimer's disease. PloS One 2011; 6: e24930.
-
(2011)
PloS One
, vol.6
-
-
Weidner, A.M.1
Bradley, M.A.2
Beckett, T.L.3
-
28
-
-
77954507297
-
Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines
-
Head E, Pop V, Sarsoza F, et al. Amyloid-beta peptide and oligomers in the brain and cerebrospinal fluid of aged canines. J Alzheimers Dis 2010; 20: 637-646.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. 637-646
-
-
Head, E.1
Pop, V.2
Sarsoza, F.3
-
29
-
-
7444247272
-
Alzheimer's beta-peptide oligomer formation at physiologic concentrations
-
LeVine H III,. Alzheimer's beta-peptide oligomer formation at physiologic concentrations. Anal Biochem 2004; 335: 81-90.
-
(2004)
Anal Biochem
, vol.335
, pp. 81-90
-
-
Levine Iii, H.1
-
30
-
-
78649846020
-
PIB binding in aged primate brain: Enrichment of high-affinity sites in humans with Alzheimer's disease
-
Rosen RF, Walker LC, Levine H III,. PIB binding in aged primate brain: enrichment of high-affinity sites in humans with Alzheimer's disease. Neurobiol Aging 2011; 32: 223-234.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 223-234
-
-
Rosen, R.F.1
Walker, L.C.2
Levine Iii, H.3
-
31
-
-
0002294347
-
A simple sequentially rejective multiple test procedure
-
Holm S,. A simple sequentially rejective multiple test procedure. Scand J Stat 1979; 6: 65-70.
-
(1979)
Scand J Stat
, vol.6
, pp. 65-70
-
-
Holm, S.1
-
32
-
-
0037172826
-
Phases of A beta-deposition in the human brain and its relevance for the development of AD
-
Thal DR, Rub U, Orantes M, Braak H,. Phases of A beta-deposition in the human brain and its relevance for the development of AD. Neurology 2002; 58: 1791-1800.
-
(2002)
Neurology
, vol.58
, pp. 1791-1800
-
-
Thal, D.R.1
Rub, U.2
Orantes, M.3
Braak, H.4
-
33
-
-
84857030932
-
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: A practical approach
-
Montine TJ, Phelps CH, Beach TG, et al. National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol 2012; 123: 1-11.
-
(2012)
Acta Neuropathol
, vol.123
, pp. 1-11
-
-
Montine, T.J.1
Phelps, C.H.2
Beach, T.G.3
-
34
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesne S, Koh MT, Kotilinek L, et al. A specific amyloid-beta protein assembly in the brain impairs memory. Nature 2006; 440: 352-357.
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesne, S.1
Koh, M.T.2
Kotilinek, L.3
-
35
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh DM, Klyubin I, Fadeeva JV, et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 2002; 416: 535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
-
36
-
-
77951928742
-
The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia
-
McDonald JM, Savva GM, Brayne C, et al. The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia. Brain 2010; 133 (pt 5): 1328-1341.
-
(2010)
Brain
, vol.133
, Issue.PART 5
, pp. 1328-1341
-
-
McDonald, J.M.1
Savva, G.M.2
Brayne, C.3
-
37
-
-
67349184808
-
Neuropathology of nondemented aging: Presumptive evidence for preclinical Alzheimer disease
-
Price JL, McKeel DW Jr, Buckles VD, et al. Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging 2009; 30: 1026-1036.
-
(2009)
Neurobiol Aging
, vol.30
, pp. 1026-1036
-
-
Price, J.L.1
McKeel, Jr.D.W.2
Buckles, V.D.3
-
38
-
-
0032988610
-
Mild cognitive impairment: Clinical characterization and outcome
-
Petersen RC, Smith GE, Waring SC, et al. Mild cognitive impairment: clinical characterization and outcome. Arch Neurol 1999; 56: 303-308.
-
(1999)
Arch Neurol
, vol.56
, pp. 303-308
-
-
Petersen, R.C.1
Smith, G.E.2
Waring, S.C.3
-
39
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh DM, Selkoe DJ,. Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron 2004; 44: 181-193.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
41
-
-
61449129068
-
[(11)C]PIB-amyloid binding and levels of Abeta40 and Abeta42 in postmortem brain tissue from Alzheimer patients
-
Svedberg MM, Hall H, Hellstrom-Lindahl E, et al. [(11)C]PIB-amyloid binding and levels of Abeta40 and Abeta42 in postmortem brain tissue from Alzheimer patients. Neurochem Int 2009; 54: 347-357.
-
(2009)
Neurochem Int
, vol.54
, pp. 347-357
-
-
Svedberg, M.M.1
Hall, H.2
Hellstrom-Lindahl, E.3
-
42
-
-
75149136696
-
Alzheimer's disease and the amyloid-beta peptide
-
Murphy MP, LeVine H III,. Alzheimer's disease and the amyloid-beta peptide. J Alzheimers Dis 2010; 19: 311-323.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 311-323
-
-
Murphy, M.P.1
Levine Iii, H.2
|