메뉴 건너뛰기




Volumn 172, Issue 8, 2015, Pages 1913-1932

Signalling pathways and mechanisms of protection in pre- and postconditioning: Historical perspective and lessons for the future

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE TRIPHOSPHATE; ANTIINFLAMMATORY AGENT; BRADYKININ; CANGRELOR; CLOPIDOGREL; FIBRINOLYTIC AGENT; G PROTEIN COUPLED RECEPTOR; GROWTH FACTOR RECEPTOR; INHALATION ANESTHETIC AGENT; LIGAND; NITRIC OXIDE; OPIATE; PHOSPHOLIPID; POTASSIUM CHANNEL; PRASUGREL; PROTEIN KINASE C; PURINERGIC P2Y12 RECEPTOR; REACTIVE OXYGEN METABOLITE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; TICAGRELOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; ANESTHETIC AGENT; ANTITHROMBOCYTIC AGENT; CARDIOTONIC AGENT;

EID: 84925852648     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12903     Document Type: Review
Times cited : (98)

References (203)
  • 8
    • 0028120906 scopus 로고
    • Collaborative overview of randomised trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients
    • Antiplatelet Trialists' Collaboration
    • Antiplatelet Trialists' Collaboration (1994). Collaborative overview of randomised trials of antiplatelet therapy-I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. BMJ 308: 81-106.
    • (1994) BMJ , vol.308 , pp. 81-106
  • 9
    • 33845981823 scopus 로고    scopus 로고
    • Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: A randomized controlled trial
    • APEX AMI Investigators, et al
    • APEX AMI Investigators, Armstrong PW, Granger CB, Adams PX, Hamm C, Holmes D Jr, et al. (2007). Pexelizumab for acute ST-elevation myocardial infarction in patients undergoing primary percutaneous coronary intervention: a randomized controlled trial. JAMA 297: 43-51.
    • (2007) JAMA , vol.297 , pp. 43-51
    • Armstrong, P.W.1    Granger, C.B.2    Adams, P.X.3    Hamm, C.4    Holmes, Jr.D.5
  • 11
    • 0030890196 scopus 로고    scopus 로고
    • Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium
    • Baines CP, Goto M, Downey JM, (1997). Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium. J Mol Cell Cardiol 29: 207-216.
    • (1997) J Mol Cell Cardiol , vol.29 , pp. 207-216
    • Baines, C.P.1    Goto, M.2    Downey, J.M.3
  • 13
    • 0037005812 scopus 로고    scopus 로고
    • Lack of effect of glycoprotein IIb/IIIa blockade on myocardial platelet or polymorphonuclear leukocyte accumulation and on infarct size after transient coronary occlusion in pigs
    • Barrabés JA, Garcia-Dorado D, Mirabet M, Lidõn R-M, Soriano B, Ruiz-Meana M, et al. (2002). Lack of effect of glycoprotein IIb/IIIa blockade on myocardial platelet or polymorphonuclear leukocyte accumulation and on infarct size after transient coronary occlusion in pigs. J Am Coll Cardiol 39: 157-165.
    • (2002) J Am Coll Cardiol , vol.39 , pp. 157-165
    • Barrabés, J.A.1    Garcia-Dorado, D.2    Mirabet, M.3    Lidõn, R.-M.4    Soriano, B.5    Ruiz-Meana, M.6
  • 15
    • 1542345704 scopus 로고    scopus 로고
    • Natriuretic peptides and myocardial ischaemia
    • Baxter GF, (2004). Natriuretic peptides and myocardial ischaemia. Basic Res Cardiol 99: 90-93.
    • (2004) Basic Res Cardiol , vol.99 , pp. 90-93
    • Baxter, G.F.1
  • 16
    • 0035197082 scopus 로고    scopus 로고
    • Cardioprotective effects of transforming growth factor-β1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK
    • Baxter GF, Mocanu MM, Brar BK, Latchman DS, Yellon DM, (2001). Cardioprotective effects of transforming growth factor-β1 during early reoxygenation or reperfusion are mediated by p42/p44 MAPK. J Cardiovasc Pharmacol 38: 930-939.
    • (2001) J Cardiovasc Pharmacol , vol.38 , pp. 930-939
    • Baxter, G.F.1    Mocanu, M.M.2    Brar, B.K.3    Latchman, D.S.4    Yellon, D.M.5
  • 19
    • 18444378127 scopus 로고    scopus 로고
    • Grade III ischemia on presentation with acute myocardial infarction predicts rapid progression of necrosis and less myocardial salvage with thrombolysis
    • Birnbaum Y, Mahaffey KW, Criger DA, Gates KB, Barbash GI, Barbagelata A, et al. (2002). Grade III ischemia on presentation with acute myocardial infarction predicts rapid progression of necrosis and less myocardial salvage with thrombolysis. Cardiology 97: 166-174.
    • (2002) Cardiology , vol.97 , pp. 166-174
    • Birnbaum, Y.1    Mahaffey, K.W.2    Criger, D.A.3    Gates, K.B.4    Barbash, G.I.5    Barbagelata, A.6
  • 20
    • 78649324875 scopus 로고    scopus 로고
    • Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
    • Boengler K, Hilfiker-Kleiner D, Heusch G, Schulz R, (2010). Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion. Basic Res Cardiol 105: 771-785.
    • (2010) Basic Res Cardiol , vol.105 , pp. 771-785
    • Boengler, K.1    Hilfiker-Kleiner, D.2    Heusch, G.3    Schulz, R.4
  • 21
    • 0033870002 scopus 로고    scopus 로고
    • Comparative study of AMP579 and adenosine in inhibition of neutrophil-mediated vascular and myocardial injury during 24 h of reperfusion
    • Budde JM, Velez DA, Zhao Z-Q, Clark KL, Morris CD, Muraki S, et al. (2000). Comparative study of AMP579 and adenosine in inhibition of neutrophil-mediated vascular and myocardial injury during 24 h of reperfusion. Cardiovasc Res 47: 294-305.
    • (2000) Cardiovasc Res , vol.47 , pp. 294-305
    • Budde, J.M.1    Velez, D.A.2    Zhao, Z.-Q.3    Clark, K.L.4    Morris, C.D.5    Muraki, S.6
  • 22
    • 35348870623 scopus 로고    scopus 로고
    • Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: Opportunities and obstacles for survival signaling
    • Burley DS, Ferdinandy P, Baxter GF, (2007). Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling. Br J Pharmacol 152: 855-869.
    • (2007) Br J Pharmacol , vol.152 , pp. 855-869
    • Burley, D.S.1    Ferdinandy, P.2    Baxter, G.F.3
  • 23
    • 2442587705 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury
    • Cai Z, Semenza GL, (2004). Phosphatidylinositol-3-kinase signaling is required for erythropoietin-mediated acute protection against myocardial ischemia/reperfusion injury. Circulation 109: 2050-2053.
    • (2004) Circulation , vol.109 , pp. 2050-2053
    • Cai, Z.1    Semenza, G.L.2
  • 24
    • 11444267248 scopus 로고    scopus 로고
    • Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: Evidence for anesthetic-induced postconditioning in rabbits
    • Chiari PC, Bienengraeber MW, Pagel PS, Krolikowski JG, Kersten JR, Warltier DC, (2005). Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits. Anesthesiology 102: 102-109.
    • (2005) Anesthesiology , vol.102 , pp. 102-109
    • Chiari, P.C.1    Bienengraeber, M.W.2    Pagel, P.S.3    Krolikowski, J.G.4    Kersten, J.R.5    Warltier, D.C.6
  • 25
    • 77958599548 scopus 로고    scopus 로고
    • Clinical trials update from the European Society of Cardiology Meeting 2010: SHIFT, PEARL-HF, STAR-heart, and HEBE-III
    • Cleland JGF, Coletta AP, Torabi A, Ahmed D, Clark AL, (2010). Clinical trials update from the European Society of Cardiology Meeting 2010: SHIFT, PEARL-HF, STAR-heart, and HEBE-III. Eur J Heart Fail 12: 1261-1264.
    • (2010) Eur J Heart Fail , vol.12 , pp. 1261-1264
    • Cleland, J.G.F.1    Coletta, A.P.2    Torabi, A.3    Ahmed, D.4    Clark, A.L.5
  • 27
    • 33646489779 scopus 로고    scopus 로고
    • Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies
    • Cohen MV, Yang X-M, Downey JM, (2006). Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies. Cardiovasc Res 70: 231-239.
    • (2006) Cardiovasc Res , vol.70 , pp. 231-239
    • Cohen, M.V.1    Yang, X.-M.2    Downey, J.M.3
  • 28
    • 34047092224 scopus 로고    scopus 로고
    • Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways
    • Cohen MV, Philipp S, Krieg T, Cui L, Kuno A, Solodushko V, et al. (2007a). Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways. J Mol Cell Cardiol 42: 842-851.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 842-851
    • Cohen, M.V.1    Philipp, S.2    Krieg, T.3    Cui, L.4    Kuno, A.5    Solodushko, V.6
  • 29
    • 34247093170 scopus 로고    scopus 로고
    • The pH hypothesis of postconditioning: Staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis
    • Cohen MV, Yang X-M, Downey JM, (2007b). The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis. Circulation 115: 1895-1903.
    • (2007) Circulation , vol.115 , pp. 1895-1903
    • Cohen, M.V.1    Yang, X.-M.2    Downey, J.M.3
  • 30
    • 50249090955 scopus 로고    scopus 로고
    • Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning's success
    • Cohen MV, Yang X-M, Downey JM, (2008). Acidosis, oxygen, and interference with mitochondrial permeability transition pore formation in the early minutes of reperfusion are critical to postconditioning's success. Basic Res Cardiol 103: 464-471.
    • (2008) Basic Res Cardiol , vol.103 , pp. 464-471
    • Cohen, M.V.1    Yang, X.-M.2    Downey, J.M.3
  • 31
    • 0030894055 scopus 로고    scopus 로고
    • Volatile anesthetics protect the ischemic rabbit myocardium from infarction
    • Cope DK, Impastato WK, Cohen MV, Downey JM, (1997). Volatile anesthetics protect the ischemic rabbit myocardium from infarction. Anesthesiology 86: 699-709.
    • (1997) Anesthesiology , vol.86 , pp. 699-709
    • Cope, D.K.1    Impastato, W.K.2    Cohen, M.V.3    Downey, J.M.4
  • 33
    • 24044492874 scopus 로고    scopus 로고
    • Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria
    • Costa ADT, Garlid KD, West IC, Lincoln TM, Downey JM, Cohen MV, et al. (2005). Protein kinase G transmits the cardioprotective signal from cytosol to mitochondria. Circ Res 97: 329-336.
    • (2005) Circ Res , vol.97 , pp. 329-336
    • Costa, A.D.T.1    Garlid, K.D.2    West, I.C.3    Lincoln, T.M.4    Downey, J.M.5    Cohen, M.V.6
  • 35
    • 0035951823 scopus 로고    scopus 로고
    • + and is a causative event in the death of myocytes in postischemic reperfusion of the heart
    • + and is a causative event in the death of myocytes in postischemic reperfusion of the heart. J Biol Chem 276: 2571-2575.
    • (2001) J Biol Chem , vol.276 , pp. 2571-2575
    • Di Lisa, F.1    Menabò, R.2    Canton, M.3    Barile, M.4    Bernardi, P.5
  • 36
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM, (1999). Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399: 601-605.
    • (1999) Nature , vol.399 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6
  • 37
    • 13044274187 scopus 로고    scopus 로고
    • Sustained in vivo cardiac protection by a rationally designed peptide that causes ε protein kinase C translocation
    • Dorn GW, Souroujon MC, Liron T, Chen C-H, Gray MO, Zhou HZ, et al. (1999). Sustained in vivo cardiac protection by a rationally designed peptide that causes ε protein kinase C translocation. Proc Natl Acad Sci U S A 96: 12798-12803.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 12798-12803
    • Dorn, G.W.1    Souroujon, M.C.2    Liron, T.3    Chen, C.-H.4    Gray, M.O.5    Zhou, H.Z.6
  • 38
    • 46149108580 scopus 로고    scopus 로고
    • Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning
    • Dost T, Cohen MV, Downey JM, (2008). Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning. Basic Res Cardiol 103: 378-384.
    • (2008) Basic Res Cardiol , vol.103 , pp. 378-384
    • Dost, T.1    Cohen, M.V.2    Downey, J.M.3
  • 39
    • 68149098562 scopus 로고    scopus 로고
    • Why do we still not have cardioprotective drugs?
    • Downey JM, Cohen MV, (2009). Why do we still not have cardioprotective drugs? Circ J 73: 1171-1177.
    • (2009) Circ J , vol.73 , pp. 1171-1177
    • Downey, J.M.1    Cohen, M.V.2
  • 42
    • 27644560497 scopus 로고    scopus 로고
    • Isoflurane postconditioning prevents opening of the mitochondrial permeability transition pore through inhibition of glycogen synthase kinase 3β
    • Feng J, Lucchinetti E, Ahuja P, Pasch T, Perriard J-C, Zaugg M, (2005). Isoflurane postconditioning prevents opening of the mitochondrial permeability transition pore through inhibition of glycogen synthase kinase 3β. Anesthesiology 103: 987-995.
    • (2005) Anesthesiology , vol.103 , pp. 987-995
    • Feng, J.1    Lucchinetti, E.2    Ahuja, P.3    Pasch, T.4    Perriard, J.-C.5    Zaugg, M.6
  • 43
    • 0035957635 scopus 로고    scopus 로고
    • Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism
    • Forbes RA, Steenbergen C, Murphy E, (2001). Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism. Circ Res 88: 802-809.
    • (2001) Circ Res , vol.88 , pp. 802-809
    • Forbes, R.A.1    Steenbergen, C.2    Murphy, E.3
  • 44
    • 33745234137 scopus 로고    scopus 로고
    • NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase
    • Förster K, Paul I, Solenkova N, Staudt A, Cohen MV, Downey JM, et al. (2006). NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Basic Res Cardiol 101: 319-326.
    • (2006) Basic Res Cardiol , vol.101 , pp. 319-326
    • Förster, K.1    Paul, I.2    Solenkova, N.3    Staudt, A.4    Cohen, M.V.5    Downey, J.M.6
  • 45
    • 84855512864 scopus 로고    scopus 로고
    • Ischaemic postconditioning revisited: Lack of effects on infarct size following primary percutaneous coronary intervention
    • Freixa X, Bellera N, Ortiz-Pérez JT, Jiménez M, Paré C, Bosch X, et al. (2012). Ischaemic postconditioning revisited: lack of effects on infarct size following primary percutaneous coronary intervention. Eur Heart J 33: 103-112.
    • (2012) Eur Heart J , vol.33 , pp. 103-112
    • Freixa, X.1    Bellera, N.2    Ortiz-Pérez, J.T.3    Jiménez, M.4    Paré, C.5    Bosch, X.6
  • 46
    • 84887824277 scopus 로고    scopus 로고
    • High density lipoprotein/sphingosine-1-phosphate-induced cardioprotection: Role of STAT3 as part of the SAFE pathway
    • Frias MA, Lecour S, James RW, Pedretti S, (2012). High density lipoprotein/sphingosine-1-phosphate-induced cardioprotection: role of STAT3 as part of the SAFE pathway. JAKSTAT 1: 92-100.
    • (2012) JAKSTAT , vol.1 , pp. 92-100
    • Frias, M.A.1    Lecour, S.2    James, R.W.3    Pedretti, S.4
  • 50
    • 33646030955 scopus 로고    scopus 로고
    • Mitochondrial permeability transition pore and postconditioning
    • Gateau-Roesch O, Argaud L, Ovize M, (2006). Mitochondrial permeability transition pore and postconditioning. Cardiovasc Res 70: 264-273.
    • (2006) Cardiovasc Res , vol.70 , pp. 264-273
    • Gateau-Roesch, O.1    Argaud, L.2    Ovize, M.3
  • 51
    • 0026091962 scopus 로고
    • Adenosine infusion during early reperfusion failed to limit myocardial infarct size in a collateral deficient species
    • Goto M, Miura T, Iliodoromitis EK, O'Leary EL, Ishimoto R, Yellon DM, et al. (1991). Adenosine infusion during early reperfusion failed to limit myocardial infarct size in a collateral deficient species. Cardiovasc Res 25: 943-949.
    • (1991) Cardiovasc Res , vol.25 , pp. 943-949
    • Goto, M.1    Miura, T.2    Iliodoromitis, E.K.3    O'Leary, E.L.4    Ishimoto, R.5    Yellon, D.M.6
  • 52
    • 0029130667 scopus 로고
    • Role of bradykinin in protection of ischemic preconditioning in rabbit hearts
    • Goto M, Liu Y, Yang X-M, Ardell JL, Cohen MV, Downey JM, (1995). Role of bradykinin in protection of ischemic preconditioning in rabbit hearts. Circ Res 77: 611-621.
    • (1995) Circ Res , vol.77 , pp. 611-621
    • Goto, M.1    Liu, Y.2    Yang, X.-M.3    Ardell, J.L.4    Cohen, M.V.5    Downey, J.M.6
  • 53
    • 0029876320 scopus 로고    scopus 로고
    • Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection
    • Goto M, Cohen MV, Van Wylen DGL, Downey JM, (1996). Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection. J Mol Cell Cardiol 28: 447-454.
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 447-454
    • Goto, M.1    Cohen, M.V.2    Van Wylen, D.G.L.3    Downey, J.M.4
  • 54
    • 0027761474 scopus 로고
    • Protection by cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts
    • Griffiths EJ, Halestrap AP, (1993). Protection by cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts. J Mol Cell Cardiol 25: 1461-1469.
    • (1993) J Mol Cell Cardiol , vol.25 , pp. 1461-1469
    • Griffiths, E.J.1    Halestrap, A.P.2
  • 55
    • 0028968606 scopus 로고
    • Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion
    • Griffiths EJ, Halestrap AP, (1995). Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion. Biochem J 307: 93-98.
    • (1995) Biochem J , vol.307 , pp. 93-98
    • Griffiths, E.J.1    Halestrap, A.P.2
  • 56
    • 1842841258 scopus 로고    scopus 로고
    • Opioid-induced cardioprotection occurs via glycogen synthase kinase β inhibition during reperfusion in intact rat hearts
    • Gross ER, Hsu AK, Gross GJ, (2004). Opioid-induced cardioprotection occurs via glycogen synthase kinase β inhibition during reperfusion in intact rat hearts. Circ Res 94: 960-966.
    • (2004) Circ Res , vol.94 , pp. 960-966
    • Gross, E.R.1    Hsu, A.K.2    Gross, G.J.3
  • 57
    • 0026547286 scopus 로고
    • Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs
    • Gross GJ, Auchampach JA, (1992). Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs. Circ Res 70: 223-233.
    • (1992) Circ Res , vol.70 , pp. 223-233
    • Gross, G.J.1    Auchampach, J.A.2
  • 58
    • 84886016180 scopus 로고    scopus 로고
    • Ischemic postconditioning during primary percutaneous coronary intervention: The effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction (POST) randomized trial
    • Hahn J-Y, Song YB, Kim EK, Yu CW, Bae J-W, Chung W-Y, et al. (2013). Ischemic postconditioning during primary percutaneous coronary intervention: the effects of postconditioning on myocardial reperfusion in patients with ST-segment elevation myocardial infarction (POST) randomized trial. Circulation 128: 1889-1896.
    • (2013) Circulation , vol.128 , pp. 1889-1896
    • Hahn, J.-Y.1    Song, Y.B.2    Kim, E.K.3    Yu, C.W.4    Bae, J.-W.5    Chung, W.-Y.6
  • 59
    • 0036783631 scopus 로고    scopus 로고
    • + channel activation by nitric oxide and protein kinase G in rabbit ventricular myocytes
    • + channel activation by nitric oxide and protein kinase G in rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol 283: H1545-H1554.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H1545-H1554
    • Han, J.1    Kim, N.2    Joo, H.3    Kim, E.4    Earm, Y.E.5
  • 60
    • 1142309743 scopus 로고    scopus 로고
    • New directions for protecting the heart against ischaemia-reperfusion injury: Targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway
    • Hausenloy DJ, Yellon DM, (2004). New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway. Cardiovasc Res 61: 448-460.
    • (2004) Cardiovasc Res , vol.61 , pp. 448-460
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 61
    • 0036023641 scopus 로고    scopus 로고
    • Inhibiting mitochondrial permeability transition pore opening: A new paradigm for myocardial preconditioning?
    • Hausenloy DJ, Maddock HL, Baxter GF, Yellon DM, (2002). Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning? Cardiovasc Res 55: 534-543.
    • (2002) Cardiovasc Res , vol.55 , pp. 534-543
    • Hausenloy, D.J.1    Maddock, H.L.2    Baxter, G.F.3    Yellon, D.M.4
  • 62
  • 63
    • 62249102192 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore as a target for preconditioning and postconditioning
    • Hausenloy DJ, Ong S-B, Yellon DM, (2009). The mitochondrial permeability transition pore as a target for preconditioning and postconditioning. Basic Res Cardiol 104: 189-202.
    • (2009) Basic Res Cardiol , vol.104 , pp. 189-202
    • Hausenloy, D.J.1    Ong, S.-B.2    Yellon, D.M.3
  • 64
    • 0015895092 scopus 로고
    • Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: A study of myocardial enzyme release
    • Hearse DJ, Humphrey SM, Chain EB, (1973). Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: a study of myocardial enzyme release. J Mol Cell Cardiol 5: 395-407.
    • (1973) J Mol Cell Cardiol , vol.5 , pp. 395-407
    • Hearse, D.J.1    Humphrey, S.M.2    Chain, E.B.3
  • 65
    • 25444512382 scopus 로고    scopus 로고
    • Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice
    • Heinzel FR, Luo Y, Li X, Boengler K, Buechert A, García-Dorado D, et al. (2005). Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice. Circ Res 97: 583-586.
    • (2005) Circ Res , vol.97 , pp. 583-586
    • Heinzel, F.R.1    Luo, Y.2    Li, X.3    Boengler, K.4    Buechert, A.5    García-Dorado, D.6
  • 66
    • 81355146580 scopus 로고    scopus 로고
    • Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion
    • Heusch G, Musiolik J, Gedik N, Skyschally A, (2011). Mitochondrial STAT3 activation and cardioprotection by ischemic postconditioning in pigs with regional myocardial ischemia/reperfusion. Circ Res 109: 1302-1308.
    • (2011) Circ Res , vol.109 , pp. 1302-1308
    • Heusch, G.1    Musiolik, J.2    Gedik, N.3    Skyschally, A.4
  • 67
    • 84885022162 scopus 로고    scopus 로고
    • Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: The Effect of Metoprolol in Cardioprotection during an Acute Myocardial Infarction (METOCARD-CNIC) trial
    • Ibanez B, Macaya C, Sánchez-Brunete V, Pizarro G, Fernández-Friera L, Mateos A, et al. (2013). Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) trial. Circulation 128: 1495-1503.
    • (2013) Circulation , vol.128 , pp. 1495-1503
    • Ibanez, B.1    Macaya, C.2    Sánchez-Brunete, V.3    Pizarro, G.4    Fernández-Friera, L.5    Mateos, A.6
  • 68
    • 0242442127 scopus 로고    scopus 로고
    • Inhibition of δ-protein kinase C protects against reperfusion injury of the ischemic heart in vivo
    • Inagaki K, Chen L, Ikeno F, Lee FH, Imahashi K-i, Bouley DM, et al. (2003a). Inhibition of δ-protein kinase C protects against reperfusion injury of the ischemic heart in vivo. Circulation 108: 2304-2307.
    • (2003) Circulation , vol.108 , pp. 2304-2307
    • Inagaki, K.1    Chen, L.2    Ikeno, F.3    Lee, F.H.4    Imahashi, K.-I.5    Bouley, D.M.6
  • 69
    • 0041932511 scopus 로고    scopus 로고
    • Additive protection of the ischemic heart ex vivo by combined treatment with δ-protein kinase C inhibitor and ε-protein kinase C activator
    • Inagaki K, Hahn HS, Dorn GW II, Mochly-Rosen D, (2003b). Additive protection of the ischemic heart ex vivo by combined treatment with δ-protein kinase C inhibitor and ε-protein kinase C activator. Circulation 108: 869-875.
    • (2003) Circulation , vol.108 , pp. 869-875
    • Inagaki, K.1    Hahn, H.S.2    Dorn, I.I.G.W.3    Mochly-Rosen, D.4
  • 71
    • 0021343227 scopus 로고
    • Canine myocardial reperfusion injury: Its reduction by the combined administration of superoxide dismutase and catalase
    • Jolly SR, Kane WJ, Bailie MB, Abrams GD, Lucchesi BR, (1984). Canine myocardial reperfusion injury: its reduction by the combined administration of superoxide dismutase and catalase. Circ Res 54: 277-285.
    • (1984) Circ Res , vol.54 , pp. 277-285
    • Jolly, S.R.1    Kane, W.J.2    Bailie, M.B.3    Abrams, G.D.4    Lucchesi, B.R.5
  • 72
    • 85047692700 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore
    • Juhaszova M, Zorov DB, Kim S-H, Pepe S, Fu Q, Fishbein KW, et al. (2004). Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest 113: 1535-1549.
    • (2004) J Clin Invest , vol.113 , pp. 1535-1549
    • Juhaszova, M.1    Zorov, D.B.2    Kim, S.-H.3    Pepe, S.4    Fu, Q.5    Fishbein, K.W.6
  • 73
    • 84868551757 scopus 로고    scopus 로고
    • Sphingosine kinase and sphingosine 1-phosphate in the heart: A decade of progress
    • Karliner JS, (2013). Sphingosine kinase and sphingosine 1-phosphate in the heart: a decade of progress. Biochim Biophys Acta 1831: 203-212.
    • (2013) Biochim Biophys Acta , vol.1831 , pp. 203-212
    • Karliner, J.S.1
  • 74
    • 0033662136 scopus 로고    scopus 로고
    • Platelet GPIIb/IIIa receptor blockade reduces infarct size in a canine model of ischemia-reperfusion
    • Kingma JG Jr, Plante S, Bogaty P, (2000). Platelet GPIIb/IIIa receptor blockade reduces infarct size in a canine model of ischemia-reperfusion. J Am Coll Cardiol 36: 2317-2324.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 2317-2324
    • Kingma, Jr.J.G.1    Plante, S.2    Bogaty, P.3
  • 75
    • 0027471927 scopus 로고
    • Ischemic preconditioning increases adenosine release and 5-nucleotidase activity during myocardial ischemia and reperfusion in dogs: Implications for myocardial salvage
    • Kitakaze M, Hori M, Takashima S, Sato H, Inoue M, Kamada T, (1993). Ischemic preconditioning increases adenosine release and 5-nucleotidase activity during myocardial ischemia and reperfusion in dogs: implications for myocardial salvage. Circulation 87: 208-215.
    • (1993) Circulation , vol.87 , pp. 208-215
    • Kitakaze, M.1    Hori, M.2    Takashima, S.3    Sato, H.4    Inoue, M.5    Kamada, T.6
  • 76
    • 35448998412 scopus 로고    scopus 로고
    • Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): Two randomised trials
    • Kitakaze M, Asakura M, Kim J, Shintani Y, Asanuma H, Hamasaki T, et al. (2007). Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials. Lancet 370: 1483-1493.
    • (2007) Lancet , vol.370 , pp. 1483-1493
    • Kitakaze, M.1    Asakura, M.2    Kim, J.3    Shintani, Y.4    Asanuma, H.5    Hamasaki, T.6
  • 77
    • 84856866392 scopus 로고    scopus 로고
    • Cardioprotective role of sphingosine-1-phosphate
    • Knapp M, (2011). Cardioprotective role of sphingosine-1-phosphate. J Physiol Pharmacol 62: 601-607.
    • (2011) J Physiol Pharmacol , vol.62 , pp. 601-607
    • Knapp, M.1
  • 78
    • 0035082669 scopus 로고    scopus 로고
    • A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo
    • Knight DR, Smith AH, Flynn DM, MacAndrew JT, Ellery SS, Kong JX, et al. (2001). A novel sodium-hydrogen exchanger isoform-1 inhibitor, zoniporide, reduces ischemic myocardial injury in vitro and in vivo. J Pharmacol Exp Ther 297: 254-259.
    • (2001) J Pharmacol Exp Ther , vol.297 , pp. 254-259
    • Knight, D.R.1    Smith, A.H.2    Flynn, D.M.3    Macandrew, J.T.4    Ellery, S.S.5    Kong, J.X.6
  • 79
    • 0037113925 scopus 로고    scopus 로고
    • Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen
    • Korichneva I, Hoyos B, Chua R, Levi E, Hammerling U, (2002). Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen. J Biol Chem 277: 44327-44331.
    • (2002) J Biol Chem , vol.277 , pp. 44327-44331
    • Korichneva, I.1    Hoyos, B.2    Chua, R.3    Levi, E.4    Hammerling, U.5
  • 80
    • 0036889534 scopus 로고    scopus 로고
    • ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases
    • Krieg T, Qin Q, McIntosh EC, Cohen MV, Downey JM, (2002). ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases. Am J Physiol Heart Circ Physiol 283: H2322-H2330.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H2322-H2330
    • Krieg, T.1    Qin, Q.2    McIntosh, E.C.3    Cohen, M.V.4    Downey, J.M.5
  • 81
    • 1542298924 scopus 로고    scopus 로고
    • Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF
    • Krieg T, Cui L, Qin Q, Cohen MV, Downey JM, (2004). Mitochondrial ROS generation following acetylcholine-induced EGF receptor transactivation requires metalloproteinase cleavage of proHB-EGF. J Mol Cell Cardiol 36: 435-443.
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 435-443
    • Krieg, T.1    Cui, L.2    Qin, Q.3    Cohen, M.V.4    Downey, J.M.5
  • 82
    • 67650094306 scopus 로고    scopus 로고
    • BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts
    • Krieg T, Liu Y, Rütz T, Methner C, Yang X-M, Dost T, et al. (2009). BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts. Eur Heart J 30: 1607-1613.
    • (2009) Eur Heart J , vol.30 , pp. 1607-1613
    • Krieg, T.1    Liu, Y.2    Rütz, T.3    Methner, C.4    Yang, X.-M.5    Dost, T.6
  • 83
    • 1042275836 scopus 로고    scopus 로고
    • Effects of glycoprotein IIb/IIIa inhibition on microvascular flow after coronary reperfusion. A quantitative myocardial contrast echocardiography study
    • Kunichika H, Ben-Yehuda O, Lafitte S, Kunichika N, Peters B, DeMaria AN, (2004). Effects of glycoprotein IIb/IIIa inhibition on microvascular flow after coronary reperfusion. A quantitative myocardial contrast echocardiography study. J Am Coll Cardiol 43: 276-283.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 276-283
    • Kunichika, H.1    Ben-Yehuda, O.2    Lafitte, S.3    Kunichika, N.4    Peters, B.5    Demaria, A.N.6
  • 86
    • 71549129836 scopus 로고    scopus 로고
    • Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway
    • Lacerda L, Somers S, Opie LH, Lecour S, (2009). Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway. Cardiovasc Res 84: 201-208.
    • (2009) Cardiovasc Res , vol.84 , pp. 201-208
    • Lacerda, L.1    Somers, S.2    Opie, L.H.3    Lecour, S.4
  • 87
    • 67349229765 scopus 로고    scopus 로고
    • Activation of the protective survivor activating factor enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?
    • Lecour S, (2009). Activation of the protective survivor activating factor enhancement (SAFE) pathway against reperfusion injury: does it go beyond the RISK pathway? J Mol Cell Cardiol 47: 32-40.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 32-40
    • Lecour, S.1
  • 88
    • 0036586721 scopus 로고    scopus 로고
    • Identification of a novel role for sphingolipid signaling in TNFα and ischemic preconditioning mediated cardioprotection
    • Lecour S, Smith RM, Woodward B, Opie LH, Rochette L, Sack MN, (2002). Identification of a novel role for sphingolipid signaling in TNFα and ischemic preconditioning mediated cardioprotection. J Mol Cell Cardiol 34: 509-518.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 509-518
    • Lecour, S.1    Smith, R.M.2    Woodward, B.3    Opie, L.H.4    Rochette, L.5    Sack, M.N.6
  • 89
    • 11144308860 scopus 로고    scopus 로고
    • Free radicals trigger TNFα-induced cardioprotection
    • Lecour S, Rochette L, Opie L, (2005a). Free radicals trigger TNFα-induced cardioprotection. Cardiovasc Res 65: 239-243.
    • (2005) Cardiovasc Res , vol.65 , pp. 239-243
    • Lecour, S.1    Rochette, L.2    Opie, L.3
  • 90
    • 33644876126 scopus 로고    scopus 로고
    • Pharmacological preconditioning with tumor necrosis factor-α activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase)
    • Lecour S, Suleman N, Deuchar GA, Somers S, Lacerda L, Huisamen B, et al. (2005b). Pharmacological preconditioning with tumor necrosis factor-α activates signal transducer and activator of transcription-3 at reperfusion without involving classic prosurvival kinases (Akt and extracellular signal-regulated kinase). Circulation 112: 3911-3918.
    • (2005) Circulation , vol.112 , pp. 3911-3918
    • Lecour, S.1    Suleman, N.2    Deuchar, G.A.3    Somers, S.4    Lacerda, L.5    Huisamen, B.6
  • 91
    • 0036256644 scopus 로고    scopus 로고
    • What does Stat3 do?
    • Levy DE, Lee C-k, (2002). What does Stat3 do? J Clin Invest 109: 1143-1148.
    • (2002) J Clin Invest , vol.109 , pp. 1143-1148
    • Levy, D.E.1    Lee, C.-K.2
  • 92
    • 84879242563 scopus 로고    scopus 로고
    • Platelet glycoprotein VI (GPVI) deletion reduces myocardial infarction in mice
    • Li H, Takizawa H, Gong X, Concepcion A, Kambayashi J, Tandon N, et al. (2007). Platelet glycoprotein VI (GPVI) deletion reduces myocardial infarction in mice. Circulation 116 (Suppl. II): II-200.
    • (2007) Circulation , vol.116 , pp. II-200
    • Li, H.1    Takizawa, H.2    Gong, X.3    Concepcion, A.4    Kambayashi, J.5    Tandon, N.6
  • 93
    • 0036194881 scopus 로고    scopus 로고
    • Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion
    • Liao Z, Brar BK, Cai Q, Stephanou A, O'Leary RM, Pennica D, et al. (2002). Cardiotrophin-1 (CT-1) can protect the adult heart from injury when added both prior to ischaemia and at reperfusion. Cardiovasc Res 53: 902-910.
    • (2002) Cardiovasc Res , vol.53 , pp. 902-910
    • Liao, Z.1    Brar, B.K.2    Cai, Q.3    Stephanou, A.4    O'Leary, R.M.5    Pennica, D.6
  • 94
    • 84861533144 scopus 로고    scopus 로고
    • Remote ischemic conditioning: From bench to bedside
    • Lim SY, Hausenloy DJ, (2012). Remote ischemic conditioning: from bench to bedside. Front Physiol 3: 27.
    • (2012) Front Physiol , vol.3 , pp. 27
    • Lim, S.Y.1    Hausenloy, D.J.2
  • 95
    • 84904707955 scopus 로고    scopus 로고
    • Effect of ischemic postconditioning on infarct size in patients with ST-elevation myocardial infarction treated by primary PCI: Results of the POSTEMI (POstconditioning in ST-Elevation Myocardial Infarction) randomized trial
    • Limalanathan S, Andersen GØ, Kløw N-E, Abdelnoor M, Hoffmann P, Eritsland J, (2014). Effect of ischemic postconditioning on infarct size in patients with ST-elevation myocardial infarction treated by primary PCI: results of the POSTEMI (POstconditioning in ST-Elevation Myocardial Infarction) randomized trial. J Am Heart Assoc 3: e000679.
    • (2014) J Am Heart Assoc , vol.3 , pp. e000679
    • Limalanathan, S.1    Andersen GØ.2    Kløw, N.-E.3    Abdelnoor, M.4    Hoffmann, P.5    Eritsland, J.6
  • 96
    • 84907396129 scopus 로고    scopus 로고
    • Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: Results of the PROTECTION AMI Randomized Controlled Trial
    • Lincoff AM, Roe M, Aylward P, Galla J, Rynkiewicz A, Guetta V, et al. (2014). Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial. Eur Heart J 35: 2516-2523.
    • (2014) Eur Heart J , vol.35 , pp. 2516-2523
    • Lincoff, A.M.1    Roe, M.2    Aylward, P.3    Galla, J.4    Rynkiewicz, A.5    Guetta, V.6
  • 98
    • 0026490398 scopus 로고
    • Ischemic preconditioning protects against infarction in rat heart
    • Liu Y, Downey JM, (1992). Ischemic preconditioning protects against infarction in rat heart. Am J Physiol Heart Circ Physiol 263: H1107-H1112.
    • (1992) Am J Physiol Heart Circ Physiol , vol.263 , pp. H1107-H1112
    • Liu, Y.1    Downey, J.M.2
  • 99
    • 0032560651 scopus 로고    scopus 로고
    • Mitochondrial ATP-dependent potassium channels: Novel effectors of cardioprotection?
    • Liu Y, Sato T, O'Rourke B, Marban E, (1998). Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection? Circulation 97: 2463-2469.
    • (1998) Circulation , vol.97 , pp. 2463-2469
    • Liu, Y.1    Sato, T.2    O'Rourke, B.3    Marban, E.4
  • 100
    • 84860807487 scopus 로고    scopus 로고
    • Exenatide reduces final infarct size in patients with ST-segment-elevation myocardial infarction and short-duration of ischemia
    • Lønborg J, Kelbæk H, Vejlstrup N, Bøtker HE, Kim WY, Holmvang L, et al. (2012). Exenatide reduces final infarct size in patients with ST-segment-elevation myocardial infarction and short-duration of ischemia. Circ Cardiovasc Interv 5: 288-295.
    • (2012) Circ Cardiovasc Interv , vol.5 , pp. 288-295
    • Lønborg, J.1    Kelbæk, H.2    Vejlstrup, N.3    Bøtker, H.E.4    Kim, W.Y.5    Holmvang, L.6
  • 101
    • 0026668169 scopus 로고
    • Mechanisms of the cardioprotective actions of WEB-2170, bepafant, a platelet activating factor antagonist, in myocardial ischemia and reperfusion
    • Ma X-L, Weyrich AS, Krantz S, Lefer AM, (1992). Mechanisms of the cardioprotective actions of WEB-2170, bepafant, a platelet activating factor antagonist, in myocardial ischemia and reperfusion. J Pharmacol Exp Ther 260: 1229-1236.
    • (1992) J Pharmacol Exp Ther , vol.260 , pp. 1229-1236
    • Ma, X.-L.1    Weyrich, A.S.2    Krantz, S.3    Lefer, A.M.4
  • 102
    • 0033571512 scopus 로고    scopus 로고
    • Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction. Results of a multicenter, randomized, placebo-controlled trial: The Acute Myocardial Infarction STudy of ADenosine (AMISTAD) Trial
    • Mahaffey KW, Puma JA, Barbagelata NA, DiCarli MF, Leesar MA, Browne KF, et al. (1999). Adenosine as an adjunct to thrombolytic therapy for acute myocardial infarction. Results of a multicenter, randomized, placebo-controlled trial: the Acute Myocardial Infarction STudy of ADenosine (AMISTAD) Trial. J Am Coll Cardiol 34: 1711-1720.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 1711-1720
    • Mahaffey, K.W.1    Puma, J.A.2    Barbagelata, N.A.3    Dicarli, M.F.4    Leesar, M.A.5    Browne, K.F.6
  • 104
    • 0015402103 scopus 로고
    • Reduction by hyaluronidase of myocardial necrosis following coronary artery occlusion
    • Maroko PR, Libby P, Bloor CM, Sobel BE, Braunwald E, (1972). Reduction by hyaluronidase of myocardial necrosis following coronary artery occlusion. Circulation 46: 430-437.
    • (1972) Circulation , vol.46 , pp. 430-437
    • Maroko, P.R.1    Libby, P.2    Bloor, C.M.3    Sobel, B.E.4    Braunwald, E.5
  • 105
    • 0030769366 scopus 로고    scopus 로고
    • Effects of ischemia, preconditioning, and adenosine deaminase inhibition on interstitial adenosine levels and infarct size
    • Martin BJ, McClanahan TB, Van Wylen DGL, Gallagher KP, (1997). Effects of ischemia, preconditioning, and adenosine deaminase inhibition on interstitial adenosine levels and infarct size. Basic Res Cardiol 92: 240-251.
    • (1997) Basic Res Cardiol , vol.92 , pp. 240-251
    • Martin, B.J.1    McClanahan, T.B.2    Van Wylen, D.G.L.3    Gallagher, K.P.4
  • 106
    • 40749126460 scopus 로고    scopus 로고
    • Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: Results of the EXPEDITION study
    • Mentzer RM Jr, Bartels C, Bolli R, Boyce S, Buckberg GD, Chaitman B, et al. (2008). Sodium-hydrogen exchange inhibition by cariporide to reduce the risk of ischemic cardiac events in patients undergoing coronary artery bypass grafting: results of the EXPEDITION study. Ann Thorac Surg 85: 1261-1270.
    • (2008) Ann Thorac Surg , vol.85 , pp. 1261-1270
    • Mentzer, Jr.R.M.1    Bartels, C.2    Bolli, R.3    Boyce, S.4    Buckberg, G.D.5    Chaitman, B.6
  • 107
    • 70350761980 scopus 로고    scopus 로고
    • Cardioprotection of bradykinin at reperfusion involves transactivation of the epidermal growth factor receptor via matrix metalloproteinase-8
    • Methner C, Donat U, Felix SB, Krieg T, (2009). Cardioprotection of bradykinin at reperfusion involves transactivation of the epidermal growth factor receptor via matrix metalloproteinase-8. Acta Physiol (Oxf) 197: 265-271.
    • (2009) Acta Physiol (Oxf) , vol.197 , pp. 265-271
    • Methner, C.1    Donat, U.2    Felix, S.B.3    Krieg, T.4
  • 109
    • 0031785918 scopus 로고    scopus 로고
    • Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits
    • Miki T, Cohen MV, Downey JM, (1998a). Opioid receptor contributes to ischemic preconditioning through protein kinase C activation in rabbits. Mol Cell Biochem 186: 3-12.
    • (1998) Mol Cell Biochem , vol.186 , pp. 3-12
    • Miki, T.1    Cohen, M.V.2    Downey, J.M.3
  • 110
    • 0031771234 scopus 로고    scopus 로고
    • Mild hypothermia reduces infarct size in the beating rabbit heart: A practical intervention for acute myocardial infarction?
    • Miki T, Liu GS, Cohen MV, Downey JM, (1998b). Mild hypothermia reduces infarct size in the beating rabbit heart: a practical intervention for acute myocardial infarction? Basic Res Cardiol 93: 372-383.
    • (1998) Basic Res Cardiol , vol.93 , pp. 372-383
    • Miki, T.1    Liu, G.S.2    Cohen, M.V.3    Downey, J.M.4
  • 112
    • 0031050219 scopus 로고    scopus 로고
    • + exchange inhibitor, Hoe 642: Difference from preconditioning in the role of protein kinase C
    • + exchange inhibitor, Hoe 642: difference from preconditioning in the role of protein kinase C. J Am Coll Cardiol 29: 693-701.
    • (1997) J Am Coll Cardiol , vol.29 , pp. 693-701
    • Miura, T.1    Ogawa, T.2    Suzuki, K.3    Goto, M.4    Shimamoto, K.5
  • 114
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • Murry CE, Jennings RB, Reimer KA, (1986). Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74: 1124-1136.
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 115
    • 59849118216 scopus 로고    scopus 로고
    • Moonlighting in mitochondria
    • Myers MG Jr, (2009). Moonlighting in mitochondria. Science 323: 723-724.
    • (2009) Science , vol.323 , pp. 723-724
    • Myers, Jr.M.G.1
  • 116
    • 0033839876 scopus 로고    scopus 로고
    • Exogenous nitric oxide can trigger a preconditioned state through a free radical mechanism, but endogenous nitric oxide is not a trigger of classical ischemic preconditioning
    • Nakano A, Liu GS, Heusch G, Downey JM, Cohen MV, (2000). Exogenous nitric oxide can trigger a preconditioned state through a free radical mechanism, but endogenous nitric oxide is not a trigger of classical ischemic preconditioning. J Mol Cell Cardiol 32: 1159-1167.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 1159-1167
    • Nakano, A.1    Liu, G.S.2    Heusch, G.3    Downey, J.M.4    Cohen, M.V.5
  • 117
    • 0031080429 scopus 로고    scopus 로고
    • Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells
    • Nash MS, Wood JPM, Osborne NN, (1997). Protein kinase C activation by serotonin potentiates agonist-induced stimulation of cAMP production in cultured rat retinal pigment epithelial cells. Exp Eye Res 64: 249-255.
    • (1997) Exp Eye Res , vol.64 , pp. 249-255
    • Nash, M.S.1    Wood, J.P.M.2    Osborne, N.N.3
  • 118
    • 0024447096 scopus 로고
    • Dual effects of protein kinase-C on receptor-stimulated cAMP accumulation in a human T-cell leukemia line
    • Nordstedt C, Kvanta A, Van der Ploeg I, Fredholm BB, (1989). Dual effects of protein kinase-C on receptor-stimulated cAMP accumulation in a human T-cell leukemia line. Eur J Pharmacol 172: 51-60.
    • (1989) Eur J Pharmacol , vol.172 , pp. 51-60
    • Nordstedt, C.1    Kvanta, A.2    Van Der Ploeg, I.3    Fredholm, B.B.4
  • 119
    • 0025947570 scopus 로고
    • Effect of intravenous adenosine on myocardial reperfusion injury in a model with low myocardial collateral blood flow
    • Norton ED, Jackson EK, Virmani R, Forman MB, (1991). Effect of intravenous adenosine on myocardial reperfusion injury in a model with low myocardial collateral blood flow. Am Heart J 122: 1283-1291.
    • (1991) Am Heart J , vol.122 , pp. 1283-1291
    • Norton, E.D.1    Jackson, E.K.2    Virmani, R.3    Forman, M.B.4
  • 121
    • 0023620353 scopus 로고
    • Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: Importance of the endothelium and the no-reflow phenomenon
    • Olafsson B, Forman MB, Puett DW, Pou A, Cates CU, Friesinger GC, et al. (1987). Reduction of reperfusion injury in the canine preparation by intracoronary adenosine: importance of the endothelium and the no-reflow phenomenon. Circulation 76: 1135-1145.
    • (1987) Circulation , vol.76 , pp. 1135-1145
    • Olafsson, B.1    Forman, M.B.2    Puett, D.W.3    Pou, A.4    Cates, C.U.5    Friesinger, G.C.6
  • 126
    • 2442714969 scopus 로고    scopus 로고
    • Cardioprotective effects of erythropoietin in the reperfused ischemic heart: A potential role for cardiac fibroblasts
    • Parsa CJ, Kim J, Riel RU, Pascal LS, Thompson RB, Petrofski JA, et al. (2004). Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem 279: 20655-20662.
    • (2004) J Biol Chem , vol.279 , pp. 20655-20662
    • Parsa, C.J.1    Kim, J.2    Riel, R.U.3    Pascal, L.S.4    Thompson, R.B.5    Petrofski, J.A.6
  • 127
    • 80053321770 scopus 로고    scopus 로고
    • Outcome comparison of 600- and 300-mg loading doses of clopidogrel in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: Results from the ARMYDA-6 MI (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Myocardial Infarction) randomized study
    • Patti G, Bárczi G, Orlic D, Mangiacapra F, Colonna G, Pasceri V, et al. (2011). Outcome comparison of 600- and 300-mg loading doses of clopidogrel in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: results from the ARMYDA-6 MI (Antiplatelet therapy for Reduction of MYocardial Damage during Angioplasty-Myocardial Infarction) randomized study. J Am Coll Cardiol 58: 1592-1599.
    • (2011) J Am Coll Cardiol , vol.58 , pp. 1592-1599
    • Patti, G.1    Bárczi, G.2    Orlic, D.3    Mangiacapra, F.4    Colonna, G.5    Pasceri, V.6
  • 128
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledgebase of drug targets and their ligands
    • NC-IUPHAR
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SPH, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
    • (2014) Nucl Acids Res , vol.42 , Issue.DATABASE ISSUE , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.H.5    Buneman, O.P.6    Al, E.7
  • 129
    • 79955538001 scopus 로고    scopus 로고
    • STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart
    • Pedretti S, Raddatz E, (2011). STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart. Basic Res Cardiol 106: 355-369.
    • (2011) Basic Res Cardiol , vol.106 , pp. 355-369
    • Pedretti, S.1    Raddatz, E.2
  • 130
    • 18044380974 scopus 로고    scopus 로고
    • Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: Role of phosphoinositide 3-kinase and protein kinase C activation
    • Penna C, Alloatti G, Cappello S, Gattullo D, Berta G, Mognetti B, et al. (2005). Platelet-activating factor induces cardioprotection in isolated rat heart akin to ischemic preconditioning: role of phosphoinositide 3-kinase and protein kinase C activation. Am J Physiol Heart Circ Physiol 288: H2512-H2520.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H2512-H2520
    • Penna, C.1    Alloatti, G.2    Cappello, S.3    Gattullo, D.4    Berta, G.5    Mognetti, B.6
  • 131
    • 79958788029 scopus 로고    scopus 로고
    • Platelet activating factor: The good and the bad in the ischemic/reperfused heart
    • Penna C, Bassino E, Alloatti G, (2011). Platelet activating factor: the good and the bad in the ischemic/reperfused heart. Exp Biol Med 236: 390-401.
    • (2011) Exp Biol Med , vol.236 , pp. 390-401
    • Penna, C.1    Bassino, E.2    Alloatti, G.3
  • 132
    • 84903384952 scopus 로고    scopus 로고
    • Protein S-nitrosylation in preconditioning and postconditioning
    • Penna C, Angotti C, Pagliaro P, (2014). Protein S-nitrosylation in preconditioning and postconditioning. Exp Biol Med 239: 647-662.
    • (2014) Exp Biol Med , vol.239 , pp. 647-662
    • Penna, C.1    Angotti, C.2    Pagliaro, P.3
  • 133
    • 79551668992 scopus 로고    scopus 로고
    • Postconditioning must be initiated in less than 1 minute following reperfusion and is dependent on adenosine 2b receptors and PI3-kinase
    • Philipp S, Yang X-M, Willenbrock R, Downey JM, Cohen MV, (2005). Postconditioning must be initiated in less than 1 minute following reperfusion and is dependent on adenosine 2b receptors and PI3-kinase. Z Kardiol 94 (Suppl. 1): V803.
    • (2005) Z Kardiol , vol.94 , pp. V803
    • Philipp, S.1    Yang, X.-M.2    Willenbrock, R.3    Downey, J.M.4    Cohen, M.V.5
  • 135
    • 0036177969 scopus 로고    scopus 로고
    • Formation of protein kinase Cε-Lck signaling modules confers cardioprotection
    • Ping P, Song C, Zhang J, Guo Y, Cao X, Li RCX, et al. (2002). Formation of protein kinase Cε-Lck signaling modules confers cardioprotection. J Clin Invest 109: 499-507.
    • (2002) J Clin Invest , vol.109 , pp. 499-507
    • Ping, P.1    Song, C.2    Zhang, J.3    Guo, Y.4    Cao, X.5    Li, R.C.X.6
  • 136
    • 48249109117 scopus 로고    scopus 로고
    • Effect of cyclosporine on reperfusion injury in acute myocardial infarction
    • Piot C, Croisille P, Staat P, Thibault H, Rioufol G, Mewton N, et al. (2008). Effect of cyclosporine on reperfusion injury in acute myocardial infarction. N Engl J Med 359: 473-481.
    • (2008) N Engl J Med , vol.359 , pp. 473-481
    • Piot, C.1    Croisille, P.2    Staat, P.3    Thibault, H.4    Rioufol, G.5    Mewton, N.6
  • 137
    • 0026017380 scopus 로고
    • Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period
    • Pitarys CJ II, Virmani R, Vildibill HD Jr, Jackson EK, Forman MB, (1991). Reduction of myocardial reperfusion injury by intravenous adenosine administered during the early reperfusion period. Circulation 83: 237-247.
    • (1991) Circulation , vol.83 , pp. 237-247
    • Pitarys, I.I.C.J.1    Virmani, R.2    Vildibill, Jr.H.D.3    Jackson, E.K.4    Forman, M.B.5
  • 138
    • 68249162142 scopus 로고    scopus 로고
    • Anesthetic-induced preconditioning delays opening of mitochondrial permeability transition pore via protein kinase C-ε-mediated pathway
    • Pravdic D, Sedlic F, Mio Y, Vladic N, Bienengraeber M, Bosnjak ZJ, (2009). Anesthetic-induced preconditioning delays opening of mitochondrial permeability transition pore via protein kinase C-ε-mediated pathway. Anesthesiology 111: 267-274.
    • (2009) Anesthesiology , vol.111 , pp. 267-274
    • Pravdic, D.1    Sedlic, F.2    Mio, Y.3    Vladic, N.4    Bienengraeber, M.5    Bosnjak, Z.J.6
  • 139
    • 0037306828 scopus 로고    scopus 로고
    • Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase
    • Qin Q, Downey JM, Cohen MV, (2003). Acetylcholine but not adenosine triggers preconditioning through PI3-kinase and a tyrosine kinase. Am J Physiol Heart Circ Physiol 284: H727-H734.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. H727-H734
    • Qin, Q.1    Downey, J.M.2    Cohen, M.V.3
  • 141
    • 27044434153 scopus 로고
    • Can we really quantitate myocardial cell injury?
    • Hearse D.J. Yellon D.M. (eds). Raven Press: New York
    • Reimer KA, Jennings RB, (1984). Can we really quantitate myocardial cell injury? In:, Hearse DJ, Yellon DM, (eds). Therapeutic Approaches to Myocardial Infarct Size Limitation. Raven Press: New York, pp. 163-184.
    • (1984) Therapeutic Approaches to Myocardial Infarct Size Limitation , pp. 163-184
    • Reimer, K.A.1    Jennings, R.B.2
  • 142
    • 0024817909 scopus 로고
    • The role of neutrophils and free radicals in the ischemic-reperfused heart: Why the confusion and controversy?
    • Reimer KA, Murry CE, Richard VJ, (1989). The role of neutrophils and free radicals in the ischemic-reperfused heart: why the confusion and controversy? J Mol Cell Cardiol 21: 1225-1239.
    • (1989) J Mol Cell Cardiol , vol.21 , pp. 1225-1239
    • Reimer, K.A.1    Murry, C.E.2    Richard, V.J.3
  • 144
    • 20344394410 scopus 로고    scopus 로고
    • A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II)
    • Ross AM, Gibbons RJ, Stone GW, Kloner RA, Alexander RW, (2005). A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II). J Am Coll Cardiol 45: 1775-1780.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1775-1780
    • Ross, A.M.1    Gibbons, R.J.2    Stone, G.W.3    Kloner, R.A.4    Alexander, R.W.5
  • 145
    • 84862284064 scopus 로고    scopus 로고
    • Cardioprotection by clopidogrel in acute ST-elevated myocardial infarction patients: A retrospective analysis
    • Roubille F, Lairez O, Mewton N, Rioufol G, Ranc S, Sanchez I, et al. (2012). Cardioprotection by clopidogrel in acute ST-elevated myocardial infarction patients: a retrospective analysis. Basic Res Cardiol 107: 275.
    • (2012) Basic Res Cardiol , vol.107 , pp. 275
    • Roubille, F.1    Lairez, O.2    Mewton, N.3    Rioufol, G.4    Ranc, S.5    Sanchez, I.6
  • 146
    • 20144373281 scopus 로고    scopus 로고
    • Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
    • Sabatine MS, Cannon CP, Gibson CM, Lõpez-Sendõn JL, Montalescot G, Theroux P, et al. (2005a). Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med 352: 1179-1189.
    • (2005) N Engl J Med , vol.352 , pp. 1179-1189
    • Sabatine, M.S.1    Cannon, C.P.2    Gibson, C.M.3    Lõpez-Sendõn, J.L.4    Montalescot, G.5    Theroux, P.6
  • 147
    • 24644495673 scopus 로고    scopus 로고
    • Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: The PCI-CLARITY study
    • Sabatine MS, Cannon CP, Gibson CM, Lõpez-Sendõn JL, Montalescot G, Theroux P, et al. (2005b). Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study. JAMA 294: 1224-1232.
    • (2005) JAMA , vol.294 , pp. 1224-1232
    • Sabatine, M.S.1    Cannon, C.P.2    Gibson, C.M.3    Lõpez-Sendõn, J.L.4    Montalescot, G.5    Theroux, P.6
  • 148
    • 77958399386 scopus 로고
    • 1 receptor activation is abolished by protein kinase C inhibitors in the rabbit
    • 1 receptor activation is abolished by protein kinase C inhibitors in the rabbit. Cardiovasc Res 29: 682-688.
    • (1995) Cardiovasc Res , vol.29 , pp. 682-688
    • Sakamoto, J.1    Miura, T.2    Goto, M.3    Iimura, O.4
  • 149
    • 19444383619 scopus 로고    scopus 로고
    • 3 and glycoprotein IIb/IIIa inhibition causes reduction in infarct size in a model of acute coronary thrombosis and primary angioplasty
    • 3 and glycoprotein IIb/IIIa inhibition causes reduction in infarct size in a model of acute coronary thrombosis and primary angioplasty. Cardiovasc Res 66: 552-561.
    • (2005) Cardiovasc Res , vol.66 , pp. 552-561
    • Sakuma, T.1    Sari, I.2    Goodman, C.N.3    Lindner, J.R.4    Klibanov, A.L.5    Kaul, S.6
  • 150
    • 77957221783 scopus 로고    scopus 로고
    • Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury
    • Sala-Mercado JA, Wider J, Undyala VVR, Jahania S, Yoo W, Mentzer RM Jr, et al. (2010). Profound cardioprotection with chloramphenicol succinate in the swine model of myocardial ischemia-reperfusion injury. Circulation 122 (Suppl. 1): S179-S184.
    • (2010) Circulation , vol.122 , pp. S179-S184
    • Sala-Mercado, J.A.1    Wider, J.2    Undyala, V.V.R.3    Jahania, S.4    Yoo, W.5    Mentzer, Jr.R.M.6
  • 151
    • 0025219050 scopus 로고
    • Ischemic preconditioning reduces infarct size in swine myocardium
    • Schott RJ, Rohmann S, Braun ER, Schaper W, (1990). Ischemic preconditioning reduces infarct size in swine myocardium. Circ Res 66: 1133-1142.
    • (1990) Circ Res , vol.66 , pp. 1133-1142
    • Schott, R.J.1    Rohmann, S.2    Braun, E.R.3    Schaper, W.4
  • 152
    • 0036783616 scopus 로고    scopus 로고
    • Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway
    • Schulman D, Latchman DS, Yellon DM, (2002). Urocortin protects the heart from reperfusion injury via upregulation of p42/p44 MAPK signaling pathway. Am J Physiol Heart Circ Physiol 283: H1481-H1488.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283 , pp. H1481-H1488
    • Schulman, D.1    Latchman, D.S.2    Yellon, D.M.3
  • 153
    • 0029039111 scopus 로고
    • Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts
    • Schultz JE, Rose E, Yao Z, Gross GJ, (1995). Evidence for involvement of opioid receptors in ischemic preconditioning in rat hearts. Am J Physiol 268: H2157-H2161.
    • (1995) Am J Physiol , vol.268 , pp. H2157-H2161
    • Schultz, J.E.1    Rose, E.2    Yao, Z.3    Gross, G.J.4
  • 157
    • 0036023629 scopus 로고    scopus 로고
    • Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFα gene
    • Smith RM, Suleman N, McCarthy J, Sack MN, (2002). Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFα gene. Cardiovasc Res 55: 553-560.
    • (2002) Cardiovasc Res , vol.55 , pp. 553-560
    • Smith, R.M.1    Suleman, N.2    McCarthy, J.3    Sack, M.N.4
  • 158
    • 84864465355 scopus 로고    scopus 로고
    • Interplay between SAFE and RISK pathways in sphingosine-1-phosphate-induced cardioprotection
    • Somers SJ, Frias M, Lacerda L, Opie LH, Lecour S, (2012). Interplay between SAFE and RISK pathways in sphingosine-1-phosphate-induced cardioprotection. Cardiovasc Drugs Ther 26: 227-237.
    • (2012) Cardiovasc Drugs Ther , vol.26 , pp. 227-237
    • Somers, S.J.1    Frias, M.2    Lacerda, L.3    Opie, L.H.4    Lecour, S.5
  • 159
    • 78049281398 scopus 로고    scopus 로고
    • Effect of postconditioning on infarct size in patients with ST elevation myocardial infarction
    • Sörensson P, Saleh N, Bouvier F, Böhm F, Settergren M, Caidahl K, et al. (2010). Effect of postconditioning on infarct size in patients with ST elevation myocardial infarction. Heart 96: 1710-1715.
    • (2010) Heart , vol.96 , pp. 1710-1715
    • Sörensson, P.1    Saleh, N.2    Bouvier, F.3    Böhm, F.4    Settergren, M.5    Caidahl, K.6
  • 160
    • 0032897260 scopus 로고    scopus 로고
    • Cyclosporin-A reduces leukocyte accumulation and protects against myocardial ischaemia reperfusion injury in rats
    • Squadrito F, Altavilla D, Squadrito G, Saitta A, Campo GM, Arlotta M, et al. (1999). Cyclosporin-A reduces leukocyte accumulation and protects against myocardial ischaemia reperfusion injury in rats. Eur J Pharmacol 364: 159-168.
    • (1999) Eur J Pharmacol , vol.364 , pp. 159-168
    • Squadrito, F.1    Altavilla, D.2    Squadrito, G.3    Saitta, A.4    Campo, G.M.5    Arlotta, M.6
  • 163
    • 0032578999 scopus 로고    scopus 로고
    • Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
    • Stephens L, Anderson K, Stokoe D, Erdjument-Bromage H, Painter GF, Holmes AB, et al. (1998). Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279: 710-714.
    • (1998) Science , vol.279 , pp. 710-714
    • Stephens, L.1    Anderson, K.2    Stokoe, D.3    Erdjument-Bromage, H.4    Painter, G.F.5    Holmes, A.B.6
  • 164
    • 84871926566 scopus 로고    scopus 로고
    • Essential role of nitric oxide in acute ischemic preconditioning: S-nitros(yl)ation versus sGC/cGMP/PKG signaling?
    • Sun J, Aponte AM, Kohr MJ, Tong G, Steenbergen C, Murphy E, (2013). Essential role of nitric oxide in acute ischemic preconditioning: S-nitros(yl)ation versus sGC/cGMP/PKG signaling? Free Radic Biol Med 54: 105-112.
    • (2013) Free Radic Biol Med , vol.54 , pp. 105-112
    • Sun, J.1    Aponte, A.M.2    Kohr, M.J.3    Tong, G.4    Steenbergen, C.5    Murphy, E.6
  • 165
    • 84890926907 scopus 로고    scopus 로고
    • Volatile anesthetic-induced preconditioning
    • Swyers T, Redford D, Larson DF, (2014). Volatile anesthetic-induced preconditioning. Perfusion 29: 10-15.
    • (2014) Perfusion , vol.29 , pp. 10-15
    • Swyers, T.1    Redford, D.2    Larson, D.F.3
  • 166
    • 27644596035 scopus 로고    scopus 로고
    • Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor γ-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury
    • Takaya N, Katoh Y, Iwabuchi K, Hayashi I, Konishi H, Itoh S, et al. (2005). Platelets activated by collagen through the immunoreceptor tyrosine-based activation motif in the Fc receptor γ-chain play a pivotal role in the development of myocardial ischemia-reperfusion injury. J Mol Cell Cardiol 39: 856-864.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 856-864
    • Takaya, N.1    Katoh, Y.2    Iwabuchi, K.3    Hayashi, I.4    Konishi, H.5    Itoh, S.6
  • 169
    • 0034687597 scopus 로고    scopus 로고
    • Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial
    • Théroux P, Chaitman BR, Danchin N, Erhardt L, Meinertz T, Schroeder JS, et al. (2000). Inhibition of the sodium-hydrogen exchanger with cariporide to prevent myocardial infarction in high-risk ischemic situations. Main results of the GUARDIAN trial. Circulation 102: 3032-3038.
    • (2000) Circulation , vol.102 , pp. 3032-3038
    • Théroux, P.1    Chaitman, B.R.2    Danchin, N.3    Erhardt, L.4    Meinertz, T.5    Schroeder, J.S.6
  • 170
    • 36049003254 scopus 로고    scopus 로고
    • Protecting the acutely ischemic myocardium beyond reperfusion therapies: Are we any closer to realizing the dream of infarct size elimination?
    • Tissier R, Cohen MV, Downey JM, (2007a). Protecting the acutely ischemic myocardium beyond reperfusion therapies: are we any closer to realizing the dream of infarct size elimination? Arch Mal Coeur Vaiss 100: 794-802.
    • (2007) Arch Mal Coeur Vaiss , vol.100 , pp. 794-802
    • Tissier, R.1    Cohen, M.V.2    Downey, J.M.3
  • 172
    • 0037040856 scopus 로고    scopus 로고
    • Phosphorylation of glycogen synthase kinase-3β during preconditioning through a phosphatidylinositol-3-kinase-dependent pathway is cardioprotective
    • Tong H, Imahashi K, Steenbergen C, Murphy E, (2002). Phosphorylation of glycogen synthase kinase-3β during preconditioning through a phosphatidylinositol-3-kinase-dependent pathway is cardioprotective. Circ Res 90: 377-379.
    • (2002) Circ Res , vol.90 , pp. 377-379
    • Tong, H.1    Imahashi, K.2    Steenbergen, C.3    Murphy, E.4
  • 173
    • 0027366790 scopus 로고
    • Ischemic preconditioning fails to limit infarct size in reserpinized rabbit myocardium. Implication of norepinephrine release in the preconditioning effect
    • Toombs CF, Wiltse AL, Shebuski RJ, (1993). Ischemic preconditioning fails to limit infarct size in reserpinized rabbit myocardium. Implication of norepinephrine release in the preconditioning effect. Circulation 88: 2351-2358.
    • (1993) Circulation , vol.88 , pp. 2351-2358
    • Toombs, C.F.1    Wiltse, A.L.2    Shebuski, R.J.3
  • 174
    • 9744278196 scopus 로고    scopus 로고
    • Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells
    • Trincavelli ML, Marroni M, Tuscano D, Ceruti S, Mazzola A, Mitro N, et al. (2004). Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells. J Neurochem 91: 1180-1190.
    • (2004) J Neurochem , vol.91 , pp. 1180-1190
    • Trincavelli, M.L.1    Marroni, M.2    Tuscano, D.3    Ceruti, S.4    Mazzola, A.5    Mitro, N.6
  • 175
    • 0027199167 scopus 로고
    • Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy
    • Van de Werf F, Janssens L, Brzostek T, Mortelmans L, Wackers FJT, Willems GM, et al. (1993). Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in patients with acute myocardial infarction receiving thrombolytic therapy. J Am Coll Cardiol 22: 407-416.
    • (1993) J Am Coll Cardiol , vol.22 , pp. 407-416
    • Van De Werf, F.1    Janssens, L.2    Brzostek, T.3    Mortelmans, L.4    Wackers, F.J.T.5    Willems, G.M.6
  • 176
    • 0025743137 scopus 로고
    • The natural history of preconditioning: Cardioprotection depends on duration of transient ischemia and time to subsequent ischemia
    • Van Winkle DM, Thornton JD, Downey DM, Downey JM, (1991). The natural history of preconditioning: cardioprotection depends on duration of transient ischemia and time to subsequent ischemia. Coron Artery Dis 2: 613-619.
    • (1991) Coron Artery Dis , vol.2 , pp. 613-619
    • Van Winkle, D.M.1    Thornton, J.D.2    Downey, D.M.3    Downey, J.M.4
  • 177
    • 0029929116 scopus 로고    scopus 로고
    • Effect of adenosine therapy at reperfusion on myocardial infarct size in dogs
    • Vander Heide RS, Reimer KA, (1996). Effect of adenosine therapy at reperfusion on myocardial infarct size in dogs. Cardiovasc Res 31: 711-718.
    • (1996) Cardiovasc Res , vol.31 , pp. 711-718
    • Vander Heide, R.S.1    Reimer, K.A.2
  • 178
    • 0026801464 scopus 로고
    • Preconditioning of the ischaemic myocardium; Involvement of the L-arginine nitric oxide pathway
    • Vegh A, Szekeres L, Parratt J, (1992). Preconditioning of the ischaemic myocardium; involvement of the L-arginine nitric oxide pathway. Br J Pharmacol 107: 648-652.
    • (1992) Br J Pharmacol , vol.107 , pp. 648-652
    • Vegh, A.1    Szekeres, L.2    Parratt, J.3
  • 179
    • 0025934380 scopus 로고
    • Myocardial reperfusion injury in the canine model after 40 minutes of ischemia: Effect of intracoronary adenosine
    • Velasco CE, Turner M, Cobb MA, Virmani R, Forman MB, (1991). Myocardial reperfusion injury in the canine model after 40 minutes of ischemia: effect of intracoronary adenosine. Am Heart J 122: 1561-1570.
    • (1991) Am Heart J , vol.122 , pp. 1561-1570
    • Velasco, C.E.1    Turner, M.2    Cobb, M.A.3    Virmani, R.4    Forman, M.B.5
  • 180
    • 0028098838 scopus 로고
    • Role of bradykinin in myocardial preconditioning
    • Wall TM, Sheehy R, Hartman JC, (1994). Role of bradykinin in myocardial preconditioning. J Pharmacol Exp Ther 270: 681-689.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 681-689
    • Wall, T.M.1    Sheehy, R.2    Hartman, J.C.3
  • 184
    • 0028798004 scopus 로고
    • Inhibition of nitric oxide synthesis does not affect ischemic preconditioning in isolated perfused rat hearts
    • Weselcouch EO, Baird AJ, Sleph P, Grover GJ, (1995). Inhibition of nitric oxide synthesis does not affect ischemic preconditioning in isolated perfused rat hearts. Am J Physiol Heart Circ Physiol 268: H242-H249.
    • (1995) Am J Physiol Heart Circ Physiol , vol.268 , pp. H242-H249
    • Weselcouch, E.O.1    Baird, A.J.2    Sleph, P.3    Grover, G.J.4
  • 187
    • 0034509373 scopus 로고    scopus 로고
    • Limitation of infarct size in rabbit hearts by the novel adenosine receptor agonist AMP 579 administered at reperfusion
    • Xu Z, Yang X-M, Cohen MV, Neumann T, Heusch G, Downey JM, (2000). Limitation of infarct size in rabbit hearts by the novel adenosine receptor agonist AMP 579 administered at reperfusion. J Mol Cell Cardiol 32: 2339-2347.
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 2339-2347
    • Xu, Z.1    Yang, X.-M.2    Cohen, M.V.3    Neumann, T.4    Heusch, G.5    Downey, J.M.6
  • 188
    • 0036784838 scopus 로고    scopus 로고
    • Protection from AMP 579 can be added to that from either cariporide or ischemic preconditioning in ischemic rabbit heart
    • Xu Z, Jiao Z, Cohen MV, Downey JM, (2002). Protection from AMP 579 can be added to that from either cariporide or ischemic preconditioning in ischemic rabbit heart. J Cardiovasc Pharmacol 40: 510-518.
    • (2002) J Cardiovasc Pharmacol , vol.40 , pp. 510-518
    • Xu, Z.1    Jiao, Z.2    Cohen, M.V.3    Downey, J.M.4
  • 189
    • 0345636630 scopus 로고    scopus 로고
    • Timing and duration of administration are crucial for antiinfarct effect of AMP 579 infused at reperfusion in rabbit heart
    • Xu Z, Downey JM, Cohen MV, (2003). Timing and duration of administration are crucial for antiinfarct effect of AMP 579 infused at reperfusion in rabbit heart. Heart Dis 5: 368-371.
    • (2003) Heart Dis , vol.5 , pp. 368-371
    • Xu, Z.1    Downey, J.M.2    Cohen, M.V.3
  • 190
    • 1542358806 scopus 로고    scopus 로고
    • NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO
    • Yang X-M, Krieg T, Cui L, Downey JM, Cohen MV, (2004a). NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO. J Mol Cell Cardiol 36: 411-421.
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 411-421
    • Yang, X.-M.1    Krieg, T.2    Cui, L.3    Downey, J.M.4    Cohen, M.V.5
  • 191
    • 3242690160 scopus 로고    scopus 로고
    • Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways
    • Yang X-M, Proctor JB, Cui L, Krieg T, Downey JM, Cohen MV, (2004b). Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways. J Am Coll Cardiol 44: 1103-1110.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1103-1110
    • Yang, X.-M.1    Proctor, J.B.2    Cui, L.3    Krieg, T.4    Downey, J.M.5    Cohen, M.V.6
  • 192
    • 11244270630 scopus 로고    scopus 로고
    • Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation
    • Yang X-M, Philipp S, Downey JM, Cohen MV, (2005). Postconditioning's protection is not dependent on circulating blood factors or cells but involves adenosine receptors and requires PI3-kinase and guanylyl cyclase activation. Basic Res Cardiol 100: 57-63.
    • (2005) Basic Res Cardiol , vol.100 , pp. 57-63
    • Yang, X.-M.1    Philipp, S.2    Downey, J.M.3    Cohen, M.V.4
  • 193
    • 33745225625 scopus 로고    scopus 로고
    • Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts
    • Yang X-M, Philipp S, Downey JM, Cohen MV, (2006a). Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts. Basic Res Cardiol 101: 311-318.
    • (2006) Basic Res Cardiol , vol.101 , pp. 311-318
    • Yang, X.-M.1    Philipp, S.2    Downey, J.M.3    Cohen, M.V.4
  • 194
    • 72449123653 scopus 로고    scopus 로고
    • Attenuation of infarction in cynomolgus monkeys: Preconditioning and postconditioning
    • Yang X-M, Liu Y, Liu Y, Tandon N, Kambayashi J, Downey JM, et al. (2010). Attenuation of infarction in cynomolgus monkeys: preconditioning and postconditioning. Basic Res Cardiol 105: 119-128.
    • (2010) Basic Res Cardiol , vol.105 , pp. 119-128
    • Yang, X.-M.1    Liu, Y.2    Liu, Y.3    Tandon, N.4    Kambayashi, J.5    Downey, J.M.6
  • 195
    • 84885172325 scopus 로고    scopus 로고
    • Triple therapy greatly increases myocardial salvage during ischemia/reperfusion in the in situ rat heart
    • Yang X-M, Cui L, Alhammouri A, Downey JM, Cohen MV, (2013a). Triple therapy greatly increases myocardial salvage during ischemia/reperfusion in the in situ rat heart. Cardiovasc Drugs Ther 27: 403-412.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 403-412
    • Yang, X.-M.1    Cui, L.2    Alhammouri, A.3    Downey, J.M.4    Cohen, M.V.5
  • 196
    • 84878318590 scopus 로고    scopus 로고
    • Two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts
    • Yang X-M, Liu Y, Cui L, Yang X, Liu Y, Tandon N, et al. (2013b). Two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts. Cardiovasc Drugs Ther 27: 109-115.
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 109-115
    • Yang, X.-M.1    Liu, Y.2    Cui, L.3    Yang, X.4    Liu, Y.5    Tandon, N.6
  • 198
    • 33746456797 scopus 로고    scopus 로고
    • Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion
    • Yang Y-J, Zhao J-L, You S-J, Wu Y-J, Jing Z-C, Yang W-X, et al. (2006b). Different effects of tirofiban and aspirin plus clopidogrel on myocardial no-reflow in a mini-swine model of acute myocardial infarction and reperfusion. Heart 92: 1131-1137.
    • (2006) Heart , vol.92 , pp. 1131-1137
    • Yang, Y.-J.1    Zhao, J.-L.2    You, S.-J.3    Wu, Y.-J.4    Jing, Z.-C.5    Yang, W.-X.6
  • 200
    • 0028348870 scopus 로고
    • Preconditioning protects ischemic rabbit heart by protein kinase C activation
    • Ytrehus K, Liu Y, Downey JM, (1994). Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol Heart Circ Physiol 266: H1145-H1152.
    • (1994) Am J Physiol Heart Circ Physiol , vol.266 , pp. H1145-H1152
    • Ytrehus, K.1    Liu, Y.2    Downey, J.M.3
  • 201
    • 0035899289 scopus 로고    scopus 로고
    • Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK, (2001). Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 345: 494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 202
    • 0035890319 scopus 로고    scopus 로고
    • + exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the Evaluation of the Safety and Cardioprotective effects of eniporide in Acute Myocardial Infarction (ESCAMI) trial
    • + exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the Evaluation of the Safety and Cardioprotective effects of eniporide in Acute Myocardial Infarction (ESCAMI) trial. J Am Coll Cardiol 38: 1644-1650.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1644-1650
    • Zeymer, U.1    Suryapranata, H.2    Monassier, J.P.3    Opolski, G.4    Davies, J.5    Rasmanis, G.6
  • 203
    • 0037623908 scopus 로고    scopus 로고
    • Inhibition of myocardial injury by ischemic postconditioning during reperfusion: Comparison with ischemic preconditioning
    • Zhao Z-Q, Corvera JS, Halkos ME, Kerendi F, Wang N-P, Guyton RA, et al. (2003). Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol 285: H579-H588.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H579-H588
    • Zhao, Z.-Q.1    Corvera, J.S.2    Halkos, M.E.3    Kerendi, F.4    Wang, N.-P.5    Guyton, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.