NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase

Basic Research in Cardiology

Volumn 101, Issue 4, 2006, Pages 319-326

  Förster, Karina ^a   Paul, Ina ^a   Solenkova, Natalia ^b   Staudt, Alexander ^a   Cohen, Michael V ^b,c   Downey, James M ^b   Felix, Stephan B ^a   Krieg, Thomas ^a  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF SOUTH ALABAMA   (United States)

^c UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Adenosine; Cardioprotection; NECA; P70S6 kinase; Reperfusion

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); CYCLOSPORIN A; HYDROGEN PEROXIDE; RAPAMYCIN; S6 KINASE; TETRAMETHYLRHODAMINE ETHYL ESTER;

ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL MEMBRANE POTENTIAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FLUORESCENCE ANALYSIS; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; ISOLATED HEART; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NONHUMAN; RAT; SIGNAL TRANSDUCTION;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ANIMALS; GLYCOGEN SYNTHASE KINASE 3; HYDROGEN PEROXIDE; MEMBRANE POTENTIALS; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL MEMBRANES; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PHOSPHORYLATION; RABBITS; RATS; RATS, WISTAR; REPERFUSION INJURY; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; VASODILATOR AGENTS;

EID: 33745234137     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-006-0593-4     Document Type: Article

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